JPS54160376A - Thiadiazole derivative*its manufacture and medical composition containing it and having antiisecretion activity - Google Patents

Thiadiazole derivative*its manufacture and medical composition containing it and having antiisecretion activity

Info

Publication number
JPS54160376A
JPS54160376A JP6330479A JP6330479A JPS54160376A JP S54160376 A JPS54160376 A JP S54160376A JP 6330479 A JP6330479 A JP 6330479A JP 6330479 A JP6330479 A JP 6330479A JP S54160376 A JPS54160376 A JP S54160376A
Authority
JP
Japan
Prior art keywords
sub
sup
alkyl
antiisecretion
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6330479A
Other languages
English (en)
Japanese (ja)
Inventor
Oregon Ierin Tobiasu
Maikuru Manto Deritsuku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Zeneca Inc
Original Assignee
Imperial Chemical Industries Ltd
ICI Americas Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd, ICI Americas Inc filed Critical Imperial Chemical Industries Ltd
Publication of JPS54160376A publication Critical patent/JPS54160376A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Dental Preparations (AREA)
JP6330479A 1978-05-24 1979-05-24 Thiadiazole derivative*its manufacture and medical composition containing it and having antiisecretion activity Pending JPS54160376A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2173778 1978-05-24

Publications (1)

Publication Number Publication Date
JPS54160376A true JPS54160376A (en) 1979-12-19

Family

ID=10167957

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6330479A Pending JPS54160376A (en) 1978-05-24 1979-05-24 Thiadiazole derivative*its manufacture and medical composition containing it and having antiisecretion activity

Country Status (22)

Country Link
US (2) US4242350A (https=)
EP (1) EP0006679B1 (https=)
JP (1) JPS54160376A (https=)
AT (1) ATE1353T1 (https=)
AU (1) AU529253B2 (https=)
CA (1) CA1124729A (https=)
CS (2) CS207790B2 (https=)
DD (1) DD143772A5 (https=)
DE (1) DE2963363D1 (https=)
DK (1) DK209079A (https=)
ES (3) ES480894A1 (https=)
FI (1) FI791656A7 (https=)
GR (1) GR73611B (https=)
HU (1) HU179492B (https=)
IE (1) IE48221B1 (https=)
IL (1) IL57388A0 (https=)
NO (1) NO791710L (https=)
NZ (1) NZ190448A (https=)
PL (1) PL118387B1 (https=)
PT (1) PT69651A (https=)
SU (1) SU1037839A3 (https=)
ZA (1) ZA792202B (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2963363D1 (en) * 1978-05-24 1982-09-09 Ici Plc Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them
EP0014057B1 (en) * 1979-01-18 1985-01-02 Imperial Chemical Industries Plc Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
GR71929B (https=) * 1979-11-13 1983-08-19 Ici Ltd
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine
EP0059597B1 (en) * 1981-02-27 1986-04-23 Imperial Chemical Industries Plc Guanidino-substituted heterocyclic derivatives having histamine h-2 antagonist activity
CA1209998A (en) * 1981-03-09 1986-08-19 David J. Gilman Amide derivatives as histamine h-2 receptor antagonists
CA1233818A (en) * 1981-03-09 1988-03-08 David J. Gilman Guanidine derivatives as histamine h-2 receptor antagonists
US4460584A (en) * 1981-03-13 1984-07-17 Imperial Chemical Industries Plc Nitrogen heterocycles
US4463005A (en) * 1981-03-18 1984-07-31 Imperial Chemical Industries Plc Bicyclic guanidines
IN158869B (https=) * 1981-03-18 1987-02-07 Ici Plc
US4451463A (en) * 1981-03-24 1984-05-29 Imperial Chemical Industries Plc Alcohol derivatives
EP0065823A1 (en) * 1981-05-13 1982-12-01 Imperial Chemical Industries Plc Heterocyclic guanidines as histamine H-2 antagonists
US4390701A (en) * 1981-05-18 1983-06-28 Bristol-Myers Company 1-Amino-2-[3-(3-piperidinomethylphenoxy)propylamino]cyclobutene-3,4-dione
US4539316A (en) * 1981-05-18 1985-09-03 Bristol-Myers Company Pyridine derivatives of 1,2-diaminocyclobutene-3,4-diones
US4546188A (en) * 1981-05-18 1985-10-08 Bristol-Myers Company Substituted 1,2-diaminocyclobutene-3,4-diones
US4607105A (en) * 1981-05-18 1986-08-19 Bristol-Myers Company 3-cyclobutene-1,2-dione intermediates
US4522943A (en) * 1981-05-18 1985-06-11 Bristol-Myers Company Chemical compounds
DE3267110D1 (de) * 1981-05-18 1985-12-05 Ici Plc Amidine derivatives
US4526973A (en) * 1981-05-18 1985-07-02 Bristol-Myers Company Chemical compounds
US4395553A (en) * 1981-05-18 1983-07-26 Bristol-Myers Company Chemical compounds
GB8419223D0 (en) * 1984-07-27 1984-08-30 Hoechst Uk Ltd Sulphamoylguanidine derivatives
JPS60255756A (ja) * 1984-06-01 1985-12-17 Ikeda Mohandou:Kk アミノアルキルフエノキシ誘導体
RU2348623C1 (ru) * 2007-05-21 2009-03-10 Государственное образовательное учреждение высшего профессионального образования "Ивановский государственный химико-технологический университет" (ИГХТУ) Способ получения 3,5-диамино-1,2,4-тиадиазола
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE842346C (de) * 1950-10-14 1952-06-26 Joachim Dipl-Chem Dr Goerdeler Verfahren zur Darstellung von 5-Amino-1, 2, 4-thiodiazolen
DE955684C (de) * 1953-10-14 1957-01-10 Bayer Ag Verfahren zur Herstellung von 5-Amino-1, 2, 4-thiodiazolen
NL266116A (https=) 1960-06-22
BE758146A (fr) 1969-10-29 1971-04-28 Smith Kline French Lab Derives de l'amidine
GB1305549A (https=) 1969-10-29 1973-02-07
GB1338169A (en) 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
GB1400319A (en) 1972-04-20 1975-07-16 Smith Kline French Lab Pharmaceutical compositions
GB1398426A (en) 1972-09-05 1975-06-18 Smith Kline French Lab Heterocyclic substituted guanidines
GB1397436A (en) 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
GB1421999A (en) 1973-02-08 1976-01-21 Smith Kline French Lab Heterocyclic containing sulphoxides
GB1419994A (en) 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
GB1421792A (en) 1973-05-17 1976-01-21 Smith Kline French Lab Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them
GB1497260A (en) 1974-06-28 1978-01-05 Smith Kline French Lab Guanidine derivatives
GB1533379A (en) 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted ureas
GB1531231A (en) 1974-09-02 1978-11-08 Smith Kline French Lab Process for the production of cyanoguanidine derivatives
GB1533380A (en) 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
GB1574214A (en) 1976-03-11 1980-09-03 Smith Kline French Lab Amidines
ZA782129B (en) * 1977-04-20 1979-03-28 Ici Ltd Hertocyclic derivatives
US4165378A (en) * 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
DE2963363D1 (en) * 1978-05-24 1982-09-09 Ici Plc Antisecretory thiadiazole derivatives, processes for their manufacture and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
CS207791B2 (en) 1981-08-31
GR73611B (https=) 1984-03-26
DD143772A5 (de) 1980-09-10
CA1124729A (en) 1982-06-01
ZA792202B (en) 1980-05-28
US4332949A (en) 1982-06-01
NZ190448A (en) 1980-12-19
US4242350A (en) 1980-12-30
PT69651A (en) 1979-06-01
ES484149A1 (es) 1980-04-16
AU4711479A (en) 1979-11-29
FI791656A7 (fi) 1981-01-01
ES480894A1 (es) 1980-02-01
EP0006679A1 (en) 1980-01-09
SU1037839A3 (ru) 1983-08-23
EP0006679B1 (en) 1982-07-21
ATE1353T1 (de) 1982-08-15
CS207790B2 (en) 1981-08-31
ES484150A1 (es) 1980-04-16
NO791710L (no) 1979-11-27
HU179492B (en) 1982-10-28
AU529253B2 (en) 1983-06-02
IE790902L (en) 1979-11-24
IL57388A0 (en) 1979-09-30
DK209079A (da) 1979-11-25
PL215764A1 (https=) 1980-06-16
PL118387B1 (en) 1981-09-30
DE2963363D1 (en) 1982-09-09
IE48221B1 (en) 1984-10-31

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