JPS54157558A - Novel carbazolyll*4**oxyypropanolamine derivative*its manufacture and drug containing it and having vasodilatation and*or betaaacceptor occlusion activity - Google Patents

Novel carbazolyll*4**oxyypropanolamine derivative*its manufacture and drug containing it and having vasodilatation and*or betaaacceptor occlusion activity

Info

Publication number
JPS54157558A
JPS54157558A JP4311979A JP4311979A JPS54157558A JP S54157558 A JPS54157558 A JP S54157558A JP 4311979 A JP4311979 A JP 4311979A JP 4311979 A JP4311979 A JP 4311979A JP S54157558 A JPS54157558 A JP S54157558A
Authority
JP
Japan
Prior art keywords
oxyypropanolamine
carbazolyll
betaaacceptor
vasodilatation
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4311979A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0123462B2 (en:Method
Inventor
Buiideman Furitsutsu
Kamupe Buorufugangu
Teiiru Matsukusu
Shiyupooneru Jisuberuto
Retsushiyu Egon
Deiitoman Kaaru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6036838&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS54157558(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of JPS54157558A publication Critical patent/JPS54157558A/ja
Publication of JPH0123462B2 publication Critical patent/JPH0123462B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP4311979A 1978-04-13 1979-04-11 Novel carbazolyll*4**oxyypropanolamine derivative*its manufacture and drug containing it and having vasodilatation and*or betaaacceptor occlusion activity Granted JPS54157558A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782815926 DE2815926A1 (de) 1978-04-13 1978-04-13 Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
JPS54157558A true JPS54157558A (en) 1979-12-12
JPH0123462B2 JPH0123462B2 (en:Method) 1989-05-02

Family

ID=6036838

Family Applications (2)

Application Number Title Priority Date Filing Date
JP4311979A Granted JPS54157558A (en) 1978-04-13 1979-04-11 Novel carbazolyll*4**oxyypropanolamine derivative*its manufacture and drug containing it and having vasodilatation and*or betaaacceptor occlusion activity
JP62076548A Pending JPS63258416A (ja) 1978-04-13 1987-03-31 カルバゾリル−（４）−オキシ−プロパノ−ルアミン誘導体を含有し血管拡張作用及び／又はβ−受容体閉塞作用を有する薬剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP62076548A Pending JPS63258416A (ja) 1978-04-13 1987-03-31 カルバゾリル−（４）−オキシ−プロパノ−ルアミン誘導体を含有し血管拡張作用及び／又はβ−受容体閉塞作用を有する薬剤

Country Status (23)

Country Link
US (1) US4503067A (en:Method)
EP (1) EP0004920B1 (en:Method)
JP (2) JPS54157558A (en:Method)
AT (1) AT375639B (en:Method)
AU (1) AU522975B2 (en:Method)
BG (1) BG61419B2 (en:Method)
CA (1) CA1129416A (en:Method)
CS (2) CS227007B2 (en:Method)
DD (1) DD143607A5 (en:Method)
DE (2) DE2815926A1 (en:Method)
DK (1) DK154555C (en:Method)
ES (1) ES479396A1 (en:Method)
FI (1) FI70406C (en:Method)
HK (1) HK2385A (en:Method)
HU (1) HU179433B (en:Method)
IL (1) IL57020A (en:Method)
LT (1) LT2628B (en:Method)
LU (1) LU88320I2 (en:Method)
MX (1) MX9203380A (en:Method)
NL (1) NL930110I2 (en:Method)
SG (1) SG52284G (en:Method)
SU (1) SU810079A3 (en:Method)
ZA (1) ZA791732B (en:Method)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004501191A (ja) * 2000-06-28 2004-01-15 テバ　ファーマシューティカル　インダストリーズ　リミティド カルベジロール
JP2008521805A (ja) * 2004-11-30 2008-06-26 アーテシアン セラピューティクス， インコーポレイテッド β−アドレナリン作用性受容体およびホスホジエステラーゼに対する阻害活性を有する強心性化合物
JP2008523025A (ja) * 2004-12-09 2008-07-03 ザック システム エス．ピー．エー． カルベジロール及びそのエナンチオマーの調製プロセス

Families Citing this family (115)

* Cited by examiner, † Cited by third party
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DE3300933A1 (de) * 1983-01-13 1984-07-19 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von d,l- und d-carazolol als antiglaukommittel sowie arzneimittel, die diese stoffe enthalten
DE3319027A1 (de) 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten
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US5393772A (en) * 1993-11-24 1995-02-28 Boehringer Mannheim Pharmaceuticals Corporation Use of, and method of treatment using, hydroxycarbazole compounds for inhibition of smooth muscle migration and proliferation
US5760069A (en) 1995-02-08 1998-06-02 Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 Method of treatment for decreasing mortality resulting from congestive heart failure
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JP2001522794A (ja) * 1997-11-12 2001-11-20 ベーリンガー・マンハイム・ファーマシューティカルズ・コーポレイション−スミスクライン・ベックマン・コーポレイション・リミテッド・パートナーシップ・ナンバー１ カルベジロールの新規経口剤形
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JP2004501191A (ja) * 2000-06-28 2004-01-15 テバ　ファーマシューティカル　インダストリーズ　リミティド カルベジロール
JP2008521805A (ja) * 2004-11-30 2008-06-26 アーテシアン セラピューティクス， インコーポレイテッド β−アドレナリン作用性受容体およびホスホジエステラーゼに対する阻害活性を有する強心性化合物
JP2008523025A (ja) * 2004-12-09 2008-07-03 ザック システム エス．ピー．エー． カルベジロール及びそのエナンチオマーの調製プロセス

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DE2815926A1 (de) 1979-10-18
ES479396A1 (es) 1980-04-16
MX9203380A (es) 1992-09-01
NL930110I1 (nl) 1993-10-18
JPH0123462B2 (en:Method) 1989-05-02
JPS63258416A (ja) 1988-10-25
AU522975B2 (en) 1982-07-08
CA1129416A (en) 1982-08-10
IL57020A (en) 1982-07-30
HU179433B (en) 1982-10-28
FI70406C (fi) 1986-09-19
CS420091A3 (en) 1992-04-15
FI70406B (fi) 1986-03-27
DD143607A5 (de) 1980-09-03
DK141979A (da) 1979-10-14
AU4582079A (en) 1979-10-18
CS227007B2 (en) 1984-04-16
LT2628B (lt) 1994-04-25
DK154555B (da) 1988-11-28
SU810079A3 (ru) 1981-02-28
FI791142A7 (fi) 1979-10-14
DK154555C (da) 1989-06-19
ZA791732B (en) 1980-05-28
SG52284G (en) 1985-03-29
NL930110I2 (nl) 1994-12-01
AT375639B (de) 1984-08-27
DE2960553D1 (en) 1981-11-05
BG61419B2 (bg) 1997-07-31
ATA276279A (de) 1984-01-15
US4503067A (en) 1985-03-05
EP0004920B1 (de) 1981-08-05
EP0004920A1 (de) 1979-10-31
LU88320I2 (de) 1994-05-04
HK2385A (en) 1985-01-18
IL57020A0 (en) 1979-07-25

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