JPS54151134A - Antitumorigenic agent - Google Patents
Antitumorigenic agentInfo
- Publication number
- JPS54151134A JPS54151134A JP5975978A JP5975978A JPS54151134A JP S54151134 A JPS54151134 A JP S54151134A JP 5975978 A JP5975978 A JP 5975978A JP 5975978 A JP5975978 A JP 5975978A JP S54151134 A JPS54151134 A JP S54151134A
- Authority
- JP
- Japan
- Prior art keywords
- antitumorigenic
- agent
- oxide
- antitumorigenic agent
- nitrofurylvinylthiazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002622 anti-tumorigenesis Effects 0.000 title abstract 6
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- NIUFVCWHFQCQJJ-UHFFFAOYSA-N 2-[2-(furan-2-yl)ethenyl]-4-nitro-3-oxido-1,3-thiazol-3-ium Chemical compound [O-][N+](=O)C1=CSC(C=CC=2OC=CC=2)=[N+]1[O-] NIUFVCWHFQCQJJ-UHFFFAOYSA-N 0.000 abstract 2
- VIBZLCFBPDDNON-UHFFFAOYSA-N 4,5-dimethyl-2-[2-(5-nitrofuran-2-yl)ethenyl]-3-oxido-1,3-thiazol-3-ium Chemical compound CC1=C(C)SC(C=CC=2OC(=CC=2)[N+]([O-])=O)=[N+]1[O-] VIBZLCFBPDDNON-UHFFFAOYSA-N 0.000 abstract 1
- 206010005003 Bladder cancer Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 201000001441 melanoma Diseases 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 201000005112 urinary bladder cancer Diseases 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5975978A JPS54151134A (en) | 1978-05-19 | 1978-05-19 | Antitumorigenic agent |
| IT22723/79A IT1114243B (it) | 1978-05-19 | 1979-05-16 | Agente antitumorale a base di derivati tiazolici |
| CH454979A CH640850A5 (de) | 1978-05-19 | 1979-05-16 | Nitrofurylvinylthiazol-n-oxid-verbindungen als antitumormittel. |
| FR7912549A FR2426052A1 (fr) | 1978-05-19 | 1979-05-17 | Composes nitrofuryl-vinyleniques, nouveaux medicaments antitumoraux |
| DE2920247A DE2920247C2 (de) | 1978-05-19 | 1979-05-18 | Verwendung einer Nitrofuryl-vinylen-thiazol-N-oxid-Verbindung zur Herstellung von Antitumormitteln |
| GB7917473A GB2021111B (en) | 1978-05-19 | 1979-05-18 | Nitro - furyl - vinylene - thiazole n-oxides as antitumour agents |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5975978A JPS54151134A (en) | 1978-05-19 | 1978-05-19 | Antitumorigenic agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS54151134A true JPS54151134A (en) | 1979-11-28 |
| JPS6136493B2 JPS6136493B2 (enrdf_load_stackoverflow) | 1986-08-19 |
Family
ID=13122504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5975978A Granted JPS54151134A (en) | 1978-05-19 | 1978-05-19 | Antitumorigenic agent |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS54151134A (enrdf_load_stackoverflow) |
| CH (1) | CH640850A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2920247C2 (enrdf_load_stackoverflow) |
| FR (1) | FR2426052A1 (enrdf_load_stackoverflow) |
| GB (1) | GB2021111B (enrdf_load_stackoverflow) |
| IT (1) | IT1114243B (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6894071B2 (en) | 2001-11-01 | 2005-05-17 | Spectrum Pharmaceuticals, Inc. | Medical compositions for intravesical treatment of bladder cancer |
| US8563592B2 (en) | 2001-11-01 | 2013-10-22 | Spectrum Pharmaceuticals, Inc. | Bladder cancer treatment and methods |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0413498U (enrdf_load_stackoverflow) * | 1990-05-24 | 1992-02-03 | ||
| ATE542531T1 (de) * | 2006-03-16 | 2012-02-15 | Women And Infants Hospital Of Rhode Island Inc | Nitrofuran-verbindungen zur behandlung von krebs und angiogenese |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1545606A1 (de) * | 1965-07-29 | 1969-08-07 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung neuer 5-Nitrofuran-Derivate |
| JPS5239033B1 (enrdf_load_stackoverflow) * | 1971-05-04 | 1977-10-03 | ||
| JPS5239033A (en) * | 1975-09-22 | 1977-03-26 | Meidensha Electric Mfg Co Ltd | An engine controlling device |
| GB2079568A (en) * | 1980-07-02 | 1982-01-20 | Hewlett Packard Co | Data compression apparatus and method |
| JPS5742662A (en) * | 1980-08-29 | 1982-03-10 | Chugai Pharmaceut Co Ltd | Benzoic acid amide derivative |
-
1978
- 1978-05-19 JP JP5975978A patent/JPS54151134A/ja active Granted
-
1979
- 1979-05-16 IT IT22723/79A patent/IT1114243B/it active
- 1979-05-16 CH CH454979A patent/CH640850A5/de not_active IP Right Cessation
- 1979-05-17 FR FR7912549A patent/FR2426052A1/fr active Granted
- 1979-05-18 GB GB7917473A patent/GB2021111B/en not_active Expired
- 1979-05-18 DE DE2920247A patent/DE2920247C2/de not_active Expired
Non-Patent Citations (1)
| Title |
|---|
| ARZNEIM.FORSCH=1967 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6894071B2 (en) | 2001-11-01 | 2005-05-17 | Spectrum Pharmaceuticals, Inc. | Medical compositions for intravesical treatment of bladder cancer |
| US7977369B2 (en) | 2001-11-01 | 2011-07-12 | Spectrum Pharmaceuticals, Inc. | Medical compositions for intravesical treatment of bladder cancer |
| US8563592B2 (en) | 2001-11-01 | 2013-10-22 | Spectrum Pharmaceuticals, Inc. | Bladder cancer treatment and methods |
| US8648108B2 (en) | 2001-11-01 | 2014-02-11 | Spectrum Pharmaceuticals, Inc. | Medical compositions for intravesical treatment of bladder cancer |
| US9295666B2 (en) | 2001-11-01 | 2016-03-29 | Spectrum Pharmaceuticals, Inc. | Bladder cancer treatment and methods |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2920247A1 (de) | 1979-11-22 |
| IT1114243B (it) | 1986-01-27 |
| IT7922723A0 (it) | 1979-05-16 |
| FR2426052A1 (fr) | 1979-12-14 |
| CH640850A5 (de) | 1984-01-31 |
| GB2021111A (en) | 1979-11-28 |
| GB2021111B (en) | 1982-11-03 |
| FR2426052B1 (enrdf_load_stackoverflow) | 1983-04-08 |
| JPS6136493B2 (enrdf_load_stackoverflow) | 1986-08-19 |
| DE2920247C2 (de) | 1985-09-19 |
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