JPS54119478A - Carbostyril derivative - Google Patents

Carbostyril derivative

Info

Publication number
JPS54119478A
JPS54119478A JP2580178A JP2580178A JPS54119478A JP S54119478 A JPS54119478 A JP S54119478A JP 2580178 A JP2580178 A JP 2580178A JP 2580178 A JP2580178 A JP 2580178A JP S54119478 A JPS54119478 A JP S54119478A
Authority
JP
Japan
Prior art keywords
formula
carbostyril
remedies
derivatives
carbon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2580178A
Other languages
Japanese (ja)
Other versions
JPS62144B2 (en
Inventor
Takao Nishi
Takashi Ueda
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP2580178A priority Critical patent/JPS54119478A/en
Publication of JPS54119478A publication Critical patent/JPS54119478A/en
Publication of JPS62144B2 publication Critical patent/JPS62144B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Carbostyril derivatives of formula I (R1 is H, lower alkyl; R2 is halogen, phenylalkoxy; n is 1W 4; n is 1 W 3; the carbon-carbon bond between the 3- and 4-positions in the carbostyril structure expresses single or double bond) and their salts.
EXAMPLE: 5-(Carboxymethoxy)-8-bromo-3,4-dihydrocarbostyril.
USE: Synthetic intermediates for amidealkoxycarbostyril derivatives that have activities inhibiting phosphodiesterase, blood platelet coagulation, and antiinflammatory activity. Further they are used as remedies and preventives for thrombosis, arteriosclerosis, hyperpiesia, asthma and so on and remedies for edema and hyperuricaciduria, anti-inflammatory agent and anti-ulcer.
PREPARATION: The reaction between a hydroxycarnostyril dderivative of formula II and a halogenofatty acid ester of formula III affords a compound of formula I.
COPYRIGHT: (C)1979,JPO&Japio
JP2580178A 1978-03-06 1978-03-06 Carbostyril derivative Granted JPS54119478A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2580178A JPS54119478A (en) 1978-03-06 1978-03-06 Carbostyril derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2580178A JPS54119478A (en) 1978-03-06 1978-03-06 Carbostyril derivative

Publications (2)

Publication Number Publication Date
JPS54119478A true JPS54119478A (en) 1979-09-17
JPS62144B2 JPS62144B2 (en) 1987-01-06

Family

ID=12175947

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2580178A Granted JPS54119478A (en) 1978-03-06 1978-03-06 Carbostyril derivative

Country Status (1)

Country Link
JP (1) JPS54119478A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4298739A (en) * 1977-06-10 1981-11-03 Otsuka Pharmaceutical Co., Ltd. Novel carbostyril derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6051472A (en) * 1983-08-31 1985-03-22 Toyo Electric Mfg Co Ltd Inverter device

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6051472A (en) * 1983-08-31 1985-03-22 Toyo Electric Mfg Co Ltd Inverter device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4298739A (en) * 1977-06-10 1981-11-03 Otsuka Pharmaceutical Co., Ltd. Novel carbostyril derivatives

Also Published As

Publication number Publication date
JPS62144B2 (en) 1987-01-06

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