JPS5315493A - Production of androstann177 one derivative - Google Patents
Production of androstann177 one derivativeInfo
- Publication number
- JPS5315493A JPS5315493A JP8493277A JP8493277A JPS5315493A JP S5315493 A JPS5315493 A JP S5315493A JP 8493277 A JP8493277 A JP 8493277A JP 8493277 A JP8493277 A JP 8493277A JP S5315493 A JPS5315493 A JP S5315493A
- Authority
- JP
- Japan
- Prior art keywords
- derivative
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/005—Degradation of the lateral chains at position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/863—Mycobacterium
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762632677 DE2632677A1 (de) | 1976-07-16 | 1976-07-16 | Verfahren zur herstellung von androstan-17-on-derivaten und deren verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5315493A true JPS5315493A (en) | 1978-02-13 |
| JPS6117477B2 JPS6117477B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1986-05-07 |
Family
ID=5983514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8493277A Granted JPS5315493A (en) | 1976-07-16 | 1977-07-15 | Production of androstann177 one derivative |
Country Status (18)
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55148083A (en) * | 1979-05-04 | 1980-11-18 | Mitsubishi Chem Ind Ltd | Microorganism |
| JPS55150893A (en) * | 1979-05-11 | 1980-11-25 | Mitsubishi Chem Ind Ltd | Novel microorganism |
| US5834576A (en) * | 1995-02-28 | 1998-11-10 | Nippon Shokubai Co., Ltd. | Acrylic acid derivatives, method for preparing the acrylic acid derivatives, and acrylic acid polymers |
| JP2013509401A (ja) * | 2009-10-29 | 2013-03-14 | インダストリー−アカデミック コーポレーション ファウンデーション，ヨンセイ ユニバーシティ | 新規血管漏出遮断剤 |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS578794A (en) * | 1980-06-17 | 1982-01-18 | Mitsubishi Chem Ind Ltd | Preparation of androstane-type steroid |
| US4444884A (en) * | 1982-05-25 | 1984-04-24 | Wisconsin Alumni Research Foundation | Process for preparing steroids |
| US4755463A (en) * | 1982-05-25 | 1988-07-05 | Wisconsin Alumni Research Foundation | Process for preparing steroids |
| NZ541374A (en) * | 2003-05-23 | 2008-09-26 | Nektar Therapeutics Al Corp | PEG derivatives having an amidocarbonate linkage |
| US9388210B2 (en) | 2011-02-25 | 2016-07-12 | Washington University | Neuroactive 17(20)-Z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same |
| PT2766380T (pt) | 2011-10-14 | 2019-07-29 | Sage Therapeutics Inc | Compostos de 19-nor pregnano 3,3-dissubstituídos, composições e seus usos |
| CN109970833B (zh) | 2012-12-18 | 2022-05-27 | 华盛顿大学 | 神经活性的甾族化合物、其前药以及利用所述化合物的治疗方法 |
| EP2956466A4 (en) | 2013-02-15 | 2016-11-02 | Univ Washington | NEUROACTIVE ENANTIOMERS 15, 16 AND 17 SUBSTITUTED STEROIDS AS MODULATORS FOR GABA-A RECEPTORS |
| US9512170B2 (en) | 2013-03-01 | 2016-12-06 | Washington University | Neuroactive 13, 17-substituted steroids as modulators for GABA type-A receptors |
| US9365502B2 (en) | 2013-03-11 | 2016-06-14 | Washington University | Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors |
| US9562026B2 (en) | 2013-03-14 | 2017-02-07 | Washington University | Neuroactive substituted cyclopent[a]anthracenes as modulators for GABA type-A receptors |
| HUE051403T2 (hu) | 2013-04-17 | 2021-03-01 | Sage Therapeutics Inc | Neuroaktív 19-nor-szteroidok kezelési eljárásokhoz |
| WO2014169831A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof |
| WO2014169836A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor neuroactive steroids and methods of use thereof |
| SMT201900066T1 (it) | 2013-04-17 | 2019-02-28 | Sage Therapeutics Inc | Steroidi di c21-n-pirazolile 19-nor c3,3-disostituiti e metodi d’uso degli stessi |
| PT3021852T (pt) | 2013-07-19 | 2021-04-21 | Sage Therapeutics Inc | Esteroides neuroativos, composições e utilizações das mesmas |
| WO2015027227A1 (en) | 2013-08-23 | 2015-02-26 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| US10246482B2 (en) | 2014-06-18 | 2019-04-02 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| US10577390B2 (en) | 2014-10-16 | 2020-03-03 | Sage Therapeutics, Inc. | Compositions and methods for treating CNS disorders |
| SMT202000414T1 (it) | 2014-10-16 | 2020-09-10 | Sage Therapeutics Inc | Composizioni e metodi per trattare disturbi del snc |
| EP3719029A1 (en) | 2014-11-27 | 2020-10-07 | Sage Therapeutics, Inc. | Compositions for inducing sedation |
| ES2857082T3 (es) | 2015-01-26 | 2021-09-28 | Sage Therapeutics Inc | Composiciones y métodos para el tratamiento de trastornos del SNC |
| JP6875996B2 (ja) | 2015-02-20 | 2021-05-26 | セージ セラピューティクス， インコーポレイテッド | 神経刺激性ステロイド、組成物、およびその使用 |
| JP7065825B2 (ja) | 2016-07-11 | 2022-05-12 | セージ セラピューティクス， インコーポレイテッド | Ｃ７、ｃ１２、およびｃ１６置換神経刺激性ステロイドおよびそれらの使用方法 |
| MA45599A (fr) | 2016-07-11 | 2019-05-15 | Sage Therapeutics Inc | Stéroïdes neuroactifs substitués en c17, c20 et c21 et leurs procédés d'utilisation |
| CA3139554A1 (en) | 2019-05-31 | 2020-12-03 | Sage Therapeutics, Inc. | Neuroactive steroids and compositions thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3451892A (en) * | 1965-10-19 | 1969-06-24 | Schering Corp | Process for the preparation of steroidal compounds |
| NL6705450A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1965-10-22 | 1968-10-21 | ||
| US3684657A (en) * | 1970-05-11 | 1972-08-15 | Searle & Co | Selective microbiological degradation of steroidal 17-alkyls |
| US3759791A (en) * | 1970-12-10 | 1973-09-18 | Searle & Co | Selective microbiological preparation of androst-4-ene-3,17-dione |
| US3738983A (en) * | 1971-08-06 | 1973-06-12 | Searle & Co | Process for the preparation of 3-(3beta,17beta-dihydroxyandrost-5-en-17alpha-yl) propionic acid gamma-lactone |
| DE2534911C2 (de) * | 1975-08-01 | 1985-04-18 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur Herstellung von 5-Androsten-17-on-Derivaten |
-
1976
- 1976-07-16 DE DE19762632677 patent/DE2632677A1/de active Granted
-
1977
- 1977-06-16 NL NL7706638A patent/NL7706638A/xx not_active Application Discontinuation
- 1977-07-01 YU YU01642/77A patent/YU164277A/xx unknown
- 1977-07-06 US US05/813,391 patent/US4179336A/en not_active Expired - Lifetime
- 1977-07-12 CH CH861377A patent/CH627190A5/de not_active IP Right Cessation
- 1977-07-13 IE IE1456/77A patent/IE45304B1/en unknown
- 1977-07-13 AT AT0504677A patent/AT363196B/de not_active IP Right Cessation
- 1977-07-13 CS CS774682A patent/CS200517B2/cs unknown
- 1977-07-14 DD DD77206207A patent/DD136142A5/xx unknown
- 1977-07-14 DD DD77206205A patent/DD136141A5/xx unknown
- 1977-07-14 DD DD77206210A patent/DD137235A5/xx unknown
- 1977-07-14 DD DD7700200065A patent/DD132439A5/xx not_active IP Right Cessation
- 1977-07-14 SE SE7708192A patent/SE440779B/xx not_active IP Right Cessation
- 1977-07-15 HU HU8019A patent/HU182790B/hu unknown
- 1977-07-15 BE BE179384A patent/BE856860A/xx not_active IP Right Cessation
- 1977-07-15 HU HU8018A patent/HU182789B/hu unknown
- 1977-07-15 SU SU772502698A patent/SU980628A3/ru active
- 1977-07-15 JP JP8493277A patent/JPS5315493A/ja active Granted
- 1977-07-15 HU HU8020A patent/HU182681B/hu unknown
- 1977-07-15 IT IT25807/77A patent/IT1077339B/it active
- 1977-07-15 GB GB29800/77A patent/GB1585786A/en not_active Expired
- 1977-07-15 HU HU77SCHE614A patent/HU179344B/hu not_active IP Right Cessation
- 1977-07-15 DK DK323677A patent/DK142372C/da not_active IP Right Cessation
- 1977-07-18 FR FR7721932A patent/FR2365588A1/fr active Granted
-
1978
- 1978-03-07 FR FR7806456A patent/FR2372174A1/fr active Pending
- 1978-03-07 FR FR7806457A patent/FR2372176A1/fr active Pending
- 1978-03-07 FR FR7806455A patent/FR2372175A1/fr active Pending
-
1981
- 1981-06-23 CH CH415281A patent/CH629222A5/de not_active IP Right Cessation
- 1981-06-23 CH CH415381A patent/CH629503A5/de not_active IP Right Cessation
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55148083A (en) * | 1979-05-04 | 1980-11-18 | Mitsubishi Chem Ind Ltd | Microorganism |
| JPS55150893A (en) * | 1979-05-11 | 1980-11-25 | Mitsubishi Chem Ind Ltd | Novel microorganism |
| US5834576A (en) * | 1995-02-28 | 1998-11-10 | Nippon Shokubai Co., Ltd. | Acrylic acid derivatives, method for preparing the acrylic acid derivatives, and acrylic acid polymers |
| JP2013509401A (ja) * | 2009-10-29 | 2013-03-14 | インダストリー−アカデミック コーポレーション ファウンデーション，ヨンセイ ユニバーシティ | 新規血管漏出遮断剤 |
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