JPH1160551A5 - - Google Patents

Info

Publication number
JPH1160551A5
JPH1160551A5 JP1998162706A JP16270698A JPH1160551A5 JP H1160551 A5 JPH1160551 A5 JP H1160551A5 JP 1998162706 A JP1998162706 A JP 1998162706A JP 16270698 A JP16270698 A JP 16270698A JP H1160551 A5 JPH1160551 A5 JP H1160551A5
Authority
JP
Japan
Prior art keywords
alkyl
phenyl
integer
substituted
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998162706A
Other languages
English (en)
Japanese (ja)
Other versions
JPH1160551A (ja
JP4177483B2 (ja
Filing date
Publication date
Priority claimed from DE19719621A external-priority patent/DE19719621A1/de
Application filed filed Critical
Publication of JPH1160551A publication Critical patent/JPH1160551A/ja
Publication of JPH1160551A5 publication Critical patent/JPH1160551A5/ja
Application granted granted Critical
Publication of JP4177483B2 publication Critical patent/JP4177483B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP16270698A 1997-05-09 1998-05-08 スルホニルアミノカルボン酸 Expired - Fee Related JP4177483B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19719621:7 1997-05-09
DE19719621A DE19719621A1 (de) 1997-05-09 1997-05-09 Sulfonylaminocarbonsäuren

Publications (3)

Publication Number Publication Date
JPH1160551A JPH1160551A (ja) 1999-03-02
JPH1160551A5 true JPH1160551A5 (enExample) 2005-09-29
JP4177483B2 JP4177483B2 (ja) 2008-11-05

Family

ID=7829102

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16270698A Expired - Fee Related JP4177483B2 (ja) 1997-05-09 1998-05-08 スルホニルアミノカルボン酸

Country Status (20)

Country Link
US (2) US6451824B1 (enExample)
EP (1) EP0877018B1 (enExample)
JP (1) JP4177483B2 (enExample)
KR (1) KR100572494B1 (enExample)
CN (1) CN1280267C (enExample)
AR (1) AR012674A1 (enExample)
AT (1) ATE238984T1 (enExample)
AU (1) AU732723B2 (enExample)
BR (1) BR9801606B1 (enExample)
CA (1) CA2237099C (enExample)
CZ (1) CZ295527B6 (enExample)
DE (2) DE19719621A1 (enExample)
DK (1) DK0877018T3 (enExample)
ES (1) ES2195220T3 (enExample)
HU (1) HU224959B1 (enExample)
ID (1) ID20807A (enExample)
PL (1) PL191876B1 (enExample)
PT (1) PT877018E (enExample)
RU (1) RU2193027C2 (enExample)
TR (1) TR199800815A2 (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1195735C (zh) * 1998-02-04 2005-04-06 诺瓦提斯公司 抑制使基质退化的金属蛋白酶的磺酰氨基衍生物
US6410580B1 (en) 1998-02-04 2002-06-25 Novartis Ag Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases
ATE227295T1 (de) * 1998-07-16 2002-11-15 Aventis Pharma Gmbh Phosphin- und phosphonsäurederivate als arzneimittel
DE19851184A1 (de) * 1998-11-06 2000-05-11 Aventis Pharma Gmbh N-Arylsulfonyl-aminosäure-omega-amide
US6677360B2 (en) 1998-12-16 2004-01-13 Bayer Aktiengesellschaft Biphenyl and biphenyl-analogous compounds as integrin antagonists
US6420396B1 (en) * 1998-12-16 2002-07-16 Beiersdorf Ag Biphenyl and biphenyl-analogous compounds as integrin antagonists
US6492394B1 (en) * 1998-12-22 2002-12-10 Syntex (U.S.A.) Llc Sulfonamide hydroxamates
EP1165530A2 (en) 1999-03-03 2002-01-02 The Procter & Gamble Company Dihetero-substituted metalloprotease inhibitors
WO2000058278A1 (fr) * 1999-03-26 2000-10-05 Shionogi & Co., Ltd. Derives d'acides amines $g(b)
GB9918684D0 (en) 1999-08-09 1999-10-13 Novartis Ag Organic compounds
EP1265863A1 (en) * 2000-03-21 2002-12-18 The Procter & Gamble Company Heterocyclic side chain containing metalloprotease inhibitors
HUP0300235A2 (hu) * 2000-03-21 2003-08-28 The Procter & Gamble Co. Heterociklikus oldalláncot tartalmazó, N-szubsztituált metalloproteáz inhibitorok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
EP1265865A2 (en) 2000-03-21 2002-12-18 The Procter & Gamble Company Difluorobutyric acid derivatives and their use as metalloprotease inhibitors
AU4888401A (en) * 2000-04-07 2001-10-23 Samsung Electronics Co., Ltd. Sulfonamide derivative as a matrix metalloproteinase inhibitor
GB0103303D0 (en) 2001-02-09 2001-03-28 Novartis Ag Organic compounds
PA8557501A1 (es) 2001-11-12 2003-06-30 Pfizer Prod Inc Benzamida, heteroarilamida y amidas inversas
WO2003042190A1 (en) 2001-11-12 2003-05-22 Pfizer Products Inc. N-alkyl-adamantyl derivatives as p2x7-receptor antagonists
PE20030701A1 (es) 2001-12-20 2003-08-21 Schering Corp Compuestos para el tratamiento de trastornos inflamatorios
US7071223B1 (en) 2002-12-31 2006-07-04 Pfizer, Inc. Benzamide inhibitors of the P2X7 receptor
PA8591801A1 (es) 2002-12-31 2004-07-26 Pfizer Prod Inc Inhibidores benzamidicos del receptor p2x7.
ATE355273T1 (de) * 2003-05-12 2006-03-15 Pfizer Prod Inc Benzamidinhibitoren des p2x7-rezeptors
EP1493740A1 (fr) * 2003-07-03 2005-01-05 Warner-Lambert Company LLC Dérivés de 5-fluoro-thiophene, leur procédé de preparation, les compositions pharmaceutiques les contenant et leur utilisation comme inhibiteurs de métalloprotéinases
US7618981B2 (en) * 2004-05-06 2009-11-17 Cytokinetics, Inc. Imidazopyridinyl-benzamide anti-cancer agents
GB0412553D0 (en) * 2004-06-04 2004-07-07 Univ Aberdeen Therapeutic agents for the treatment of bone conditions
RU2006146675A (ru) * 2004-06-29 2008-07-10 Пфайзер Продактс Инк. (Us) Способ получения производных 5-[4-(2-гидроксипропил)-3,5-диоксо-4,5-дигидро-3н-[1,2,4] триазин-2-ил] бензамида снятием защиты с промежуточных продуктов, содержащих защищенный гидроксил
BRPI0512651A (pt) * 2004-06-29 2008-03-25 Pfizer Prod Inc método para a preparação de derivados de 5-4-(2-hidroxietil)-3,5-dioxo-4,5 dihidro-3h-1,2,4-trizin-2-ila com atividade inibidora de p2x7 por reaçaõ do derivado não substituìdo na posição 4 da trizina com um oxirano na presença de um ácido de lewis
JP2008504363A (ja) * 2004-06-29 2008-02-14 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー Ｐ２ｘ７受容体のベンズアミド阻害剤を利用する併用療法
US7576222B2 (en) 2004-12-28 2009-08-18 Wyeth Alkynyl-containing tryptophan derivative inhibitors of TACE/matrix metalloproteinase
GB0705400D0 (en) 2007-03-21 2007-05-02 Univ Aberdeen Therapeutic compounds andm their use
SA08290668B1 (ar) * 2007-10-25 2012-02-12 شيونوجي آند كو.، ليمتد مشتقات أمين لها نشاط مضاد لمستقبل npy y5 واستخداماتها
GB0817208D0 (en) 2008-09-19 2008-10-29 Pimco 2664 Ltd Therapeutic apsap compounds and their use
GB0817207D0 (en) 2008-09-19 2008-10-29 Pimco 2664 Ltd therapeutic apsac compounds and their use
JP5710498B2 (ja) * 2008-12-23 2015-04-30 アクイラス ファーマシューティカルズ， インコーポレイテッド 疼痛および他の疾患の処置のための化合物および方法
GB201311361D0 (en) 2013-06-26 2013-08-14 Pimco 2664 Ltd Compounds and their therapeutic use
CA2970578C (en) 2014-12-17 2024-01-02 Pimco 2664 Limited N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2764262B2 (ja) * 1987-08-28 1998-06-11 持田製薬株式会社 ヒダントイン誘導体及びそれを有効成分とする医薬組成物
TW201303B (enExample) * 1990-07-05 1993-03-01 Hoffmann La Roche
GB9200210D0 (en) * 1992-01-07 1992-02-26 British Bio Technology Compounds
US5455258A (en) * 1993-01-06 1995-10-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
US5506242A (en) * 1993-01-06 1996-04-09 Ciba-Geigy Corporation Arylsufonamido-substituted hydroxamic acids
US6022898A (en) * 1994-06-22 2000-02-08 British Biotech Pharmaceuticals Limited Metalloproteinase inhibitors
US5863949A (en) * 1995-03-08 1999-01-26 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
DK0821671T3 (da) * 1995-04-20 2001-04-23 Pfizer Arylsulfonylhydroxamsyrederivater som MMP- og TNF-inhibitorer
KR980009238A (ko) * 1995-07-28 1998-04-30 우에노 도시오 설포닐아미노산 유도체
US5977141A (en) * 1995-11-17 1999-11-02 Warner-Lambert Company Sulfonamide inhibitors of matrix metalloproteinases
CA2242416C (en) * 1996-01-23 2006-03-21 Shionogi & Co., Ltd. Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same
JP3628335B2 (ja) * 1996-01-23 2005-03-09 塩野義製薬株式会社 スルホン化されたアミノ酸誘導体およびそれを含有するメタロプロティナーゼ阻害剤
SK282863B6 (sk) * 1996-05-17 2002-12-03 Warner-Lambert Company Bifenylsulfonamidy, ich použitie a farmaceutické prostriedky na ich báze
US5756545A (en) * 1997-04-21 1998-05-26 Warner-Lambert Company Biphenysulfonamide matrix metal alloproteinase inhibitors
EP0877019B1 (de) * 1997-05-09 2001-12-12 Hoechst Aktiengesellschaft Substituierte Diaminocarbonsäuren

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