JPH10316662A5 - - Google Patents

Info

Publication number
JPH10316662A5
JPH10316662A5 JP1998130752A JP13075298A JPH10316662A5 JP H10316662 A5 JPH10316662 A5 JP H10316662A5 JP 1998130752 A JP1998130752 A JP 1998130752A JP 13075298 A JP13075298 A JP 13075298A JP H10316662 A5 JPH10316662 A5 JP H10316662A5
Authority
JP
Japan
Prior art keywords
alkyl
phenyl
covalent bond
substituted
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998130752A
Other languages
English (en)
Japanese (ja)
Other versions
JP4384277B2 (ja
JPH10316662A (ja
Filing date
Publication date
Priority claimed from DE19719817A external-priority patent/DE19719817A1/de
Application filed filed Critical
Publication of JPH10316662A publication Critical patent/JPH10316662A/ja
Publication of JPH10316662A5 publication Critical patent/JPH10316662A5/ja
Application granted granted Critical
Publication of JP4384277B2 publication Critical patent/JP4384277B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP13075298A 1997-05-13 1998-05-13 置換された６−および７−アミノテトラヒドロイソキノリンカルボン酸 Expired - Fee Related JP4384277B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19719817A DE19719817A1 (de) 1997-05-13 1997-05-13 Substituierte 6- und 7-Aminotetrahydroisochinolincarbonsäuren
DE19719817:1 1997-05-13

Publications (3)

Publication Number Publication Date
JPH10316662A JPH10316662A (ja) 1998-12-02
JPH10316662A5 true JPH10316662A5 (enExample) 2005-09-29
JP4384277B2 JP4384277B2 (ja) 2009-12-16

Family

ID=7829213

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13075298A Expired - Fee Related JP4384277B2 (ja) 1997-05-13 1998-05-13 置換された６−および７−アミノテトラヒドロイソキノリンカルボン酸

Country Status (18)

Country Link
US (1) US5962471A (enExample)
EP (1) EP0878467B1 (enExample)
JP (1) JP4384277B2 (enExample)
KR (1) KR19980086989A (enExample)
CN (1) CN1199045A (enExample)
AR (1) AR012684A1 (enExample)
AT (1) ATE207903T1 (enExample)
AU (1) AU731079B2 (enExample)
BR (1) BR9803694A (enExample)
CA (1) CA2237382A1 (enExample)
CZ (1) CZ145298A3 (enExample)
DE (2) DE19719817A1 (enExample)
DK (1) DK0878467T3 (enExample)
ES (1) ES2166577T3 (enExample)
HU (1) HUP9801072A3 (enExample)
PT (1) PT878467E (enExample)
RU (1) RU2212405C2 (enExample)
TR (1) TR199800841A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG88737A1 (en) 1996-10-30 2002-05-21 Tanabe Seiyaku Co S type 2-substituted hydroxy-2-indolidinylbutyric ester compounds and process for preparation thereof
FR2795730B1 (fr) * 1999-07-01 2001-08-31 Adir Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2001049249A2 (en) * 1999-12-31 2001-07-12 Rutgers, The State University Pharmaceutical formulation for regulating the timed release of biologically active compounds based on a polymer matrix
US7521061B2 (en) * 1999-12-31 2009-04-21 Rutgers, The State University Of New Jersey Pharmaceutical formulation for regulating the timed release of biologically active compounds based on a polymer matrix
US6548667B2 (en) * 2000-04-07 2003-04-15 Samsung Electronics Co. Ltd. Sulfonamide derivative as a matrix metalloproteinase inhibitor
GB0011409D0 (en) * 2000-05-11 2000-06-28 Smithkline Beecham Plc Novel compounds
US6770647B2 (en) * 2001-08-17 2004-08-03 Bristol-Myers Squibb Pharma Company Bicyclic hydroxamates as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE)
US20020055637A1 (en) * 2001-12-21 2002-05-09 Song Liu Methods for synthesis of amino-tetrahydroisoquinoline-carboxylic acids
US6608193B2 (en) 2001-12-21 2003-08-19 The Procter & Gamble Company Methods for synthesis of amino-tetrahydroisoquinoline ring compounds
US6566524B2 (en) * 2001-12-21 2003-05-20 The Procter & Gamble Co. Methods for synthesis of amino-tetrahydroisoquinoline-sulfonamide hydroxamic acids
MXPA05001784A (es) * 2002-08-13 2005-04-25 Warner Lambert Co Derivados de isoquinolina como inhibidores de metaloproteinasa de matriz.
DE10344936A1 (de) * 2003-09-27 2005-04-21 Aventis Pharma Gmbh Bicyclische Iminosäurederivate als Inhibitoren von Matrix-Metalloproteinasen
US7576222B2 (en) 2004-12-28 2009-08-18 Wyeth Alkynyl-containing tryptophan derivative inhibitors of TACE/matrix metalloproteinase
DE102005015040A1 (de) * 2005-03-31 2006-10-05 Sanofi-Aventis Deutschland Gmbh Substituierte Tetrahydroisochinoline als MMP-Inhibitoren, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament
JP5098011B2 (ja) * 2006-11-20 2012-12-12 国立大学法人山口大学 創傷治癒促進剤
GB0706072D0 (en) * 2007-03-28 2007-05-09 Sterix Ltd Compound

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU575349A1 (ru) * 1975-12-29 1977-10-05 Донецкий государственный университет Способ получени арилсульфонамидных производных 1,2-дигидрохинолина
US4315935A (en) * 1980-04-14 1982-02-16 Smithkline Corporation N,N'-Bis[substituted-1,2,3,4-tetrahydroisoquinolinolyl]disulfonylimides and antiallergic compositions and method of use
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4681889A (en) * 1985-12-02 1987-07-21 Syntex (U.S.A.) Inc. Method for treating cardiovascular disease with calcium channel antagonists
US4613606A (en) * 1985-12-02 1986-09-23 Syntex (U.S.A.) Inc. Tetrahydroisoquinoline derivatives
JP2764262B2 (ja) * 1987-08-28 1998-06-11 持田製薬株式会社 ヒダントイン誘導体及びそれを有効成分とする医薬組成物
TW201303B (enExample) * 1990-07-05 1993-03-01 Hoffmann La Roche
US5455258A (en) * 1993-01-06 1995-10-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
US5506242A (en) * 1993-01-06 1996-04-09 Ciba-Geigy Corporation Arylsufonamido-substituted hydroxamic acids
US5552419A (en) * 1993-01-06 1996-09-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
FR2701480B1 (fr) * 1993-02-15 1995-05-24 Sanofi Elf Composés à groupe sulfamoyle et amidino, leur procédé de préparation et les compositions pharmaceutiques les contenant.
US5714497A (en) * 1993-02-15 1998-02-03 Sanofi Compounds bearing sulphamoyl and amidino radicals, their preparation process and pharmaceutical compositions containing them
WO1995029892A1 (en) * 1994-04-28 1995-11-09 The Du Pont Merck Pharmaceutical Company Hydroxamic acid and amino acid derivatives and their use as anti-arthritic agents
AU690703B2 (en) * 1994-06-22 1998-04-30 British Biotech Pharmaceuticals Limited Metalloproteinase inhibitors
US5863949A (en) * 1995-03-08 1999-01-26 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
CA2218503C (en) * 1995-04-20 2001-07-24 Pfizer Inc. Arylsulfonyl hydroxamic acid derivatives
TR199800849T2 (xx) * 1995-11-13 1998-07-21 Hoechst Aktiengesellschaft Siklikle heterosiklik N-ikame edilmi� alfa-iminohidroksamla karbon asitleri
GB9613547D0 (en) * 1996-06-27 1996-08-28 Pharmacia Spa Matrix metalloproteinase inhibitors

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