|
US7175847B1
(en)
*
|
1995-06-07 |
2007-02-13 |
Biogen Idec Inc. |
Treating intestinal inflammation with anti-CD80 antibodies that do not inhibit CD80 binding to CTLA-4
|
|
US6113898A
(en)
*
|
1995-06-07 |
2000-09-05 |
Idec Pharmaceuticals Corporation |
Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
|
|
US20030180290A1
(en)
*
|
1995-06-07 |
2003-09-25 |
Idec Pharmaceuticals Corporation |
Anti-CD80 antibody having ADCC activity for ADCC mediated killing of B cell lymphoma cells alone or in combination with other therapies
|
|
US7153508B2
(en)
*
|
1995-06-07 |
2006-12-26 |
Biogen Idec Inc. |
Treatment of B cell lymphoma using anti-CD80 antibodies that do not inhibit the binding of CD80 to CTLA-4
|
|
US6090382A
(en)
*
|
1996-02-09 |
2000-07-18 |
Basf Aktiengesellschaft |
Human antibodies that bind human TNFα
|
|
ATE239041T1
(de)
|
1996-02-09 |
2003-05-15 |
Basf Ag |
Humane antikörper welche an humanen tnfalpha binden
|
|
ATE219376T1
(de)
*
|
1996-03-20 |
2002-07-15 |
Bristol Myers Squibb Co |
Verfahren zur inhibierung der immunreaktion durch blockierung der gp39/cd40 und ctla4/cd28/b7 routen und zusammensetzung zu deren verwendung
|
|
BR9713498A
(pt)
*
|
1996-11-08 |
2000-02-29 |
Idec Pharma Corp |
Identificação de interações de ligação singulares entre alguns anticorpos e os antìgenos co-estimulatórios b7.1 e b7.2 humanos
|
|
EP0988321A2
(en)
*
|
1997-06-20 |
2000-03-29 |
Innogenetics N.V. |
B7-binding molecules for treating immune diseases
|
|
IT1293795B1
(it)
*
|
1997-07-28 |
1999-03-10 |
Angelini Ricerche Spa |
Farmaco attivo nel ridurre la produzione di proteina mcp-1
|
|
IL146005A0
(en)
|
1999-05-07 |
2002-07-25 |
Genentech Inc |
Treatment of autoimmune diseases with antagonists which bind to b cell surface markers
|
|
EP1216056A1
(en)
*
|
1999-07-12 |
2002-06-26 |
Genentech Inc. |
Blocking immune response to a foreign antigen using an antagonist which binds to cd20
|
|
US6451284B1
(en)
*
|
1999-08-11 |
2002-09-17 |
Idec Pharmaceuticals Corporation |
Clinical parameters for determining hematologic toxicity prior to radioimmunotheraphy
|
|
SE9903895D0
(sv)
*
|
1999-10-28 |
1999-10-28 |
Active Biotech Ab |
Novel compounds
|
|
US20020028178A1
(en)
*
|
2000-07-12 |
2002-03-07 |
Nabil Hanna |
Treatment of B cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications
|
|
US20010055593A1
(en)
*
|
2000-03-14 |
2001-12-27 |
Joseph Sypek |
Use of rapamycin and agents that inhibit B7 activity in immunomodulation
|
|
EP1283722A1
(en)
*
|
2000-03-31 |
2003-02-19 |
Idec Pharmaceuticals Corporation |
Combined use of anti-cytokine antibodies or antagonists and anti-cd20 for the treatment of b cell lymphoma
|
|
US6379900B1
(en)
|
2000-05-09 |
2002-04-30 |
Conceptual Mindworks, Inc. |
Compositions and methods of use of 8-nitroguanine
|
|
MXPA02012157A
(es)
*
|
2000-06-09 |
2003-06-06 |
Bristol Myers Squibb Co |
Metodos para regular una respuesta inmune mediada por celulas al bloquear se°ales linfociticas y al bloquear la adhesion mediada por el antigeno 1 asociado con la funcion de linfocitos.
|
|
AU6836301A
(en)
*
|
2000-06-20 |
2002-01-02 |
Idec Pharma Corp |
Treatment of b-cell associated diseases such as malignancies and autoimmune diseases using a cold anti-cd20 antibody/radiolabeled anti-cd22 antibody combination
|
|
CA2630062C
(en)
|
2000-07-03 |
2014-10-14 |
Bristol-Myers Squibb Company |
Methods for treating graft versus host disease and immune disorders associated with rejection using a soluble ctla4 molecule
|
|
US20040022787A1
(en)
|
2000-07-03 |
2004-02-05 |
Robert Cohen |
Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID
|
|
US8568766B2
(en)
|
2000-08-24 |
2013-10-29 |
Gattadahalli M. Anantharamaiah |
Peptides and peptide mimetics to treat pathologies associated with eye disease
|
|
WO2002022212A2
(en)
*
|
2000-09-18 |
2002-03-21 |
Idec Pharmaceuticals Corporation |
Combination therapy for treatment of autoimmune diseases using b cell depleting/immunoregulatory antibody combination
|
|
MXPA03006699A
(es)
*
|
2001-01-26 |
2004-05-31 |
Univ Emory |
Metodos de induccion de tolerancia al trasplante de organos y correccion de hemoglobinopatias.
|
|
US20070065436A1
(en)
*
|
2001-01-31 |
2007-03-22 |
Biogen Idec Inc. |
Anti-cd80 antibody having adcc activity for adcc mediated killing of b cell lymphoma cells alone or in combination with other therapies
|
|
US20030103971A1
(en)
*
|
2001-11-09 |
2003-06-05 |
Kandasamy Hariharan |
Immunoregulatory antibodies and uses thereof
|
|
US20020159996A1
(en)
*
|
2001-01-31 |
2002-10-31 |
Kandasamy Hariharan |
Use of CD23 antagonists for the treatment of neoplastic disorders
|
|
US20030211107A1
(en)
*
|
2002-01-31 |
2003-11-13 |
Kandasamy Hariharan |
Use of CD23 antagonists for the treatment of neoplastic disorders
|
|
WO2002102303A2
(en)
*
|
2001-05-01 |
2002-12-27 |
Medimmune, Inc. |
Crystals and structure of synagis fab
|
|
ATE390931T1
(de)
*
|
2001-05-23 |
2008-04-15 |
Bristol Myers Squibb Co |
Verfahren zum schützen eines allogenen inseltransplantats mit löslichen ctla4- mutationsmolekülen
|
|
ATE420964T1
(de)
|
2001-11-16 |
2009-01-15 |
Biogen Idec Inc |
Polycistronische expression von antikörpern in cho zellen
|
|
KR20040105740A
(ko)
|
2002-02-25 |
2004-12-16 |
엘란 파마슈티칼스, 인크. |
염증 치료제의 투여 방법
|
|
US20030180292A1
(en)
*
|
2002-03-14 |
2003-09-25 |
Idec Pharmaceuticals |
Treatment of B cell malignancies using anti-CD40L antibodies in combination with anti-CD20 antibodies and/or chemotherapeutics and radiotherapy
|
|
EP3254673A1
(en)
|
2002-11-13 |
2017-12-13 |
The UAB Research Foundation |
Synthetic single domain polypeptides mimicking apolipoprotein e and methods of use
|
|
NZ545314A
(en)
*
|
2003-08-04 |
2009-03-31 |
Bristol Myers Squibb Co |
Methods for treating cardiovascular disease using a soluble CTLA4 molecule
|
|
CA2541523A1
(en)
*
|
2003-10-21 |
2005-05-06 |
Applied Research Systems Ars Holding N.V. |
Minimal dna sequence acting as a chromatin insulator and its use in protein expression
|
|
JP2007534305A
(ja)
*
|
2003-11-07 |
2007-11-29 |
アムジェン インコーポレイテッド |
サル免疫グロブリン配列
|
|
US8029783B2
(en)
*
|
2005-02-02 |
2011-10-04 |
Genentech, Inc. |
DR5 antibodies and articles of manufacture containing same
|
|
CN100369931C
(zh)
*
|
2005-04-07 |
2008-02-20 |
苏州大学 |
抗人b7-1分子单克隆抗体及其应用
|
|
WO2008118324A2
(en)
|
2007-03-26 |
2008-10-02 |
Macrogenics, Inc. |
Composition and method of treating cancer with an anti-uroplakin ib antibody
|
|
AU2008296487A1
(en)
|
2007-08-28 |
2009-03-12 |
The Uab Research Foundation |
Synthetic apolipoprotein E mimicking polypeptides and methods of use
|
|
JP2010538005A
(ja)
|
2007-08-28 |
2010-12-09 |
ユーエービー リサーチ ファウンデーション |
合成アポリポ蛋白質e模倣ポリペプチドおよび使用方法
|
|
SI2769729T1
(sl)
|
2007-09-04 |
2019-06-28 |
Compugen Ltd. |
Polipeptidin in polinukleotidi in njihove uporabe kot tarča zdravila za izdelavo zdravil in bioloških zdravil
|
|
EP3062106B1
(en)
|
2008-04-16 |
2020-11-11 |
The Johns Hopkins University |
Method for determining androgen receptor variants in prostate cancer
|
|
EP2483304B1
(en)
|
2009-09-29 |
2016-05-04 |
F.Hoffmann-La Roche Ag |
Pre-filtration adjustment of buffer solutes for high concentration immunoglobulin preparation
|
|
US9540426B2
(en)
|
2009-10-06 |
2017-01-10 |
Bristol-Myers Squibb Company |
Mammalian cell culture processes for protein production
|
|
EP2322149A1
(en)
|
2009-11-03 |
2011-05-18 |
Universidad del Pais Vasco |
Methods and compositions for the treatment of ischemia
|
|
EP2338492A1
(en)
|
2009-12-24 |
2011-06-29 |
Universidad del Pais Vasco |
Methods and compositions for the treatment of alzheimer
|
|
WO2011103389A1
(en)
|
2010-02-19 |
2011-08-25 |
Cornell University |
Method to treat autoimmune demyelinating diseases and other autoimmune or inflammatory diseases
|
|
DK2542256T3
(da)
|
2010-03-04 |
2019-08-26 |
Macrogenics Inc |
Antistoffer reagerende med b7-h3, immunologisk aktive fragmenter deraf og anvendelser deraf
|
|
PH12012501751A1
(en)
|
2010-03-04 |
2012-11-12 |
Macrogenics Inc |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
|
MX380504B
(es)
|
2010-06-03 |
2025-03-12 |
Pharmacyclics Llc |
El uso de inhibidores de la tirosina quinasa de bruton (btk).
|
|
CN103201290B
(zh)
|
2010-06-14 |
2016-09-28 |
莱克拉生物医学股份公司 |
S100a4抗体及其治疗用途
|
|
JP5972871B2
(ja)
|
2010-07-20 |
2016-08-17 |
テバ・ファーマシューティカルズ・オーストラリア・ピーティワイ・リミテッド |
抗il−23ヘテロ二量体特異的抗体
|
|
EP3722808B1
(en)
|
2010-10-25 |
2024-09-11 |
Biogen MA Inc. |
Methods for determining differences in alpha-4 integrin activity by correlating differences in svcam and/or smadcam levels
|
|
EP2638060A2
(en)
|
2010-11-10 |
2013-09-18 |
Laboratorios Del Dr. Esteve, S.A. |
Highly immunogenic hiv p24 sequences
|
|
EP2665746B1
(en)
|
2011-01-17 |
2020-10-28 |
Lykera Biomed S.A. |
Antibodies against the s100p protein for the treatment and diagnosis of cancer
|
|
WO2012100835A1
(en)
|
2011-01-28 |
2012-08-02 |
Laboratorios Del Dr. Esteve, S.A. |
Methods and compositions for the treatment of aids
|
|
WO2012149197A2
(en)
|
2011-04-27 |
2012-11-01 |
Abbott Laboratories |
Methods for controlling the galactosylation profile of recombinantly-expressed proteins
|
|
WO2012170071A1
(en)
|
2011-06-06 |
2012-12-13 |
Elan Pharmaceuticas, Inc |
Mcam antagonists and methods of treatment
|
|
EP2726503B1
(en)
|
2011-06-30 |
2019-09-04 |
Compugen Ltd. |
Polypeptides and uses thereof for treatment of autoimmune disorders and infection
|
|
EP3495389A1
(en)
|
2011-09-30 |
2019-06-12 |
Teva Pharmaceuticals Australia Pty Ltd |
Antibodies against tl1a and uses thereof
|
|
JP2015504413A
(ja)
|
2011-10-28 |
2015-02-12 |
パトリス リミテッド |
Pat−lm1エピトープおよびそれを使用するための方法
|
|
AU2013216320A1
(en)
|
2012-02-01 |
2014-04-03 |
Compugen Ltd. |
C10RF32 antibodies, and uses thereof for treatment of cancer
|
|
US9067990B2
(en)
|
2013-03-14 |
2015-06-30 |
Abbvie, Inc. |
Protein purification using displacement chromatography
|
|
US9150645B2
(en)
|
2012-04-20 |
2015-10-06 |
Abbvie, Inc. |
Cell culture methods to reduce acidic species
|
|
US9181572B2
(en)
|
2012-04-20 |
2015-11-10 |
Abbvie, Inc. |
Methods to modulate lysine variant distribution
|
|
US9249182B2
(en)
|
2012-05-24 |
2016-02-02 |
Abbvie, Inc. |
Purification of antibodies using hydrophobic interaction chromatography
|
|
HK1206073A1
(en)
|
2012-07-24 |
2015-12-31 |
药品循环有限责任公司 |
Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk)
|
|
HK1211981A1
(en)
|
2012-09-02 |
2016-06-03 |
Abbvie Inc. |
Methods to control protein heterogeneity
|
|
US9512214B2
(en)
|
2012-09-02 |
2016-12-06 |
Abbvie, Inc. |
Methods to control protein heterogeneity
|
|
TWI595007B
(zh)
|
2012-09-10 |
2017-08-11 |
Neotope Biosciences Ltd |
抗mcam抗體及相關使用方法
|
|
AU2014213009B2
(en)
|
2013-02-01 |
2019-01-03 |
Kira Biotech Pty Limited |
Anti-CD83 antibodies and use thereof
|
|
PT2953971T
(pt)
|
2013-02-07 |
2023-05-02 |
Csl Ltd |
Proteínas de ligação à il-11r e suas utilizações
|
|
US9487587B2
(en)
|
2013-03-05 |
2016-11-08 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
|
|
SG11201507230PA
(en)
|
2013-03-12 |
2015-10-29 |
Abbvie Inc |
Human antibodies that bind human tnf-alpha and methods of preparing the same
|
|
US9017687B1
(en)
|
2013-10-18 |
2015-04-28 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same using displacement chromatography
|
|
CA2904170A1
(en)
|
2013-03-14 |
2014-09-25 |
University Of Maryland, Baltimore |
Androgen receptor down-regulating agents and uses thereof
|
|
WO2014151878A2
(en)
|
2013-03-14 |
2014-09-25 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
|
|
WO2014159579A1
(en)
|
2013-03-14 |
2014-10-02 |
Abbvie Inc. |
MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
|
|
ES2639227T3
(es)
|
2013-04-09 |
2017-10-25 |
Lykera Biomed S.A. |
Anticuerpos anti S100A7 para el tratamiento y diagnóstico de cáncer
|
|
KR20160058774A
(ko)
|
2013-08-12 |
2016-05-25 |
토카이 파마슈티컬, 아이엔씨. |
안드로겐-표적 치료제를 이용하는 종양 질환 치료를 위한 바이오마커
|
|
US9598667B2
(en)
|
2013-10-04 |
2017-03-21 |
Abbvie Inc. |
Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
|
|
US9085618B2
(en)
|
2013-10-18 |
2015-07-21 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same
|
|
US8946395B1
(en)
|
2013-10-18 |
2015-02-03 |
Abbvie Inc. |
Purification of proteins using hydrophobic interaction chromatography
|
|
US9181337B2
(en)
|
2013-10-18 |
2015-11-10 |
Abbvie, Inc. |
Modulated lysine variant species compositions and methods for producing and using the same
|
|
US20150139988A1
(en)
|
2013-11-15 |
2015-05-21 |
Abbvie, Inc. |
Glycoengineered binding protein compositions
|
|
EP2876114A1
(en)
|
2013-11-25 |
2015-05-27 |
Consejo Superior De Investigaciones Científicas |
Antibodies against CCR9 and applications thereof
|
|
TR201900665T4
(tr)
|
2013-11-28 |
2019-02-21 |
B Creative Sweden Ab |
Diyabetik nefropatinin tedavi yöntemi.
|
|
EP2883883A1
(en)
|
2013-12-16 |
2015-06-17 |
Cardio3 Biosciences S.A. |
Therapeutic targets and agents useful in treating ischemia reperfusion injury
|
|
CN105979965B
(zh)
|
2013-12-18 |
2021-07-09 |
杰特有限公司 |
治疗伤口的方法
|
|
US9885086B2
(en)
|
2014-03-20 |
2018-02-06 |
Pharmacyclics Llc |
Phospholipase C gamma 2 and resistance associated mutations
|
|
WO2015179404A1
(en)
|
2014-05-19 |
2015-11-26 |
The Johns Hopkins University |
Methods for identifying androgen receptor splice variants in subjects having castration resistant prostate cancer
|
|
JP7081923B2
(ja)
|
2014-07-31 |
2022-06-07 |
ユーエイビー リサーチ ファンデーション |
アポe模倣ペプチド及び血漿コレステロールを取り除くためのより高い効果
|
|
MX2017001656A
(es)
*
|
2014-08-08 |
2017-07-24 |
Pharmacyclics Llc |
Combinaciones de inhibidor de tirosina cinasa de bruton y usos de estas.
|
|
WO2016033114A1
(en)
|
2014-08-25 |
2016-03-03 |
The Johns Hopkins University |
Methods and compositions related to prostate cancer therapeutics
|
|
AU2015336931B2
(en)
|
2014-10-23 |
2021-04-29 |
Kira Biotech Pty Limited |
CD83 binding proteins and uses thereof
|
|
EP3233120A4
(en)
|
2014-12-19 |
2018-05-30 |
Monash University |
Il-21 antibodies
|
|
AU2016361462B2
(en)
|
2015-11-27 |
2023-09-21 |
Csl Limited |
CD131 binding proteins and uses thereof
|
|
CN105628935A
(zh)
*
|
2016-03-01 |
2016-06-01 |
广东医学院附属医院 |
一种检测人尿中cd80的试剂盒
|
|
CN109069633A
(zh)
|
2016-04-15 |
2018-12-21 |
宏观基因有限公司 |
新颖的b7-h3-结合分子、其抗体药物缀合物及其使用方法
|
|
CA3034105A1
(en)
|
2016-09-23 |
2018-03-29 |
Csl Limited |
Coagulation factor binding proteins and uses thereof
|
|
KR101926834B1
(ko)
|
2017-03-21 |
2018-12-07 |
동아에스티 주식회사 |
항-dr5 항체 및 그의 용도
|
|
CA3058290A1
(en)
|
2017-04-18 |
2018-10-25 |
Universite Libre De Bruxelles |
Biomarkers and targets for proliferative diseases
|
|
KR102755742B1
(ko)
|
2017-09-11 |
2025-01-15 |
모나쉬 유니버시티 |
인간 트롬빈 수용체 par4 결합 단백질
|
|
KR102715492B1
(ko)
|
2017-10-18 |
2024-10-11 |
씨에스엘 리미티드 |
인간 혈청 알부민 변이체 및 이의 용도
|
|
JP7390729B2
(ja)
|
2018-03-23 |
2023-12-04 |
ユニヴェルシテ リブル ドゥ ブリュッセル |
Wntシグナル伝達アゴニスト分子
|
|
CN112118859A
(zh)
|
2018-05-16 |
2020-12-22 |
杰特有限公司 |
1型可溶性补体受体变体及其用途
|
|
US12139537B2
(en)
*
|
2018-06-22 |
2024-11-12 |
Junten Bio Co., Ltd. |
Antibody inducing immune tolerance, induced lymphocyte, and cell therapy agent therapeutic method using induced lymphocyte
|
|
EP3892299A4
(en)
*
|
2018-12-07 |
2022-11-30 |
ONO Pharmaceutical Co., Ltd. |
IMMUNOSUPPRESSANT
|
|
JP7807372B2
(ja)
|
2019-12-20 |
2026-01-27 |
ハドソン インスティチュート オブ メディカル リサーチ |
Cxcl10結合タンパク質及びその使用
|
|
WO2022013613A2
(en)
|
2020-07-17 |
2022-01-20 |
Onena Medicines S.L. |
Antibodies against lefty proteins
|
|
EP4433084A1
(en)
|
2021-11-19 |
2024-09-25 |
Lykera Biomed, S.A. |
Treatment and diagnosis of diseases associated to pathogenic fibrosis
|
|
WO2025149667A1
(en)
|
2024-01-12 |
2025-07-17 |
Pheon Therapeutics Ltd |
Antibody drug conjugates and uses thereof
|
|
WO2025171411A1
(en)
|
2024-02-09 |
2025-08-14 |
Herophilus, Inc. |
Compositions and methods related to modulating macrophage migration inhibitory factor (mif)-cd74 signaling and related treatments for neuroinflammatory conditions
|
|
EP4703381A1
(en)
|
2024-09-03 |
2026-03-04 |
Institució Catalana de Recerca i Estudis Avançats |
Antibodies against icam-1 and applications thereof
|
|
WO2026068859A1
(en)
|
2024-09-30 |
2026-04-02 |
Université Libre de Bruxelles |
Wnt signaling agonist molecules in the treatment of a bone-related disease or disorder
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