JPH11505528A - 胃腸治療剤としての表皮成長因子の使用 - Google Patents
胃腸治療剤としての表皮成長因子の使用Info
- Publication number
- JPH11505528A JPH11505528A JP8533624A JP53362496A JPH11505528A JP H11505528 A JPH11505528 A JP H11505528A JP 8533624 A JP8533624 A JP 8533624A JP 53362496 A JP53362496 A JP 53362496A JP H11505528 A JPH11505528 A JP H11505528A
- Authority
- JP
- Japan
- Prior art keywords
- egf
- growth factor
- animals
- epidermal growth
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/168—Steroids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/184—Hormones
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Birds (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Child & Adolescent Psychology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fodder In General (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.動物における病原体の腸コロニー形成の予防または処置のためのEGFの 使用。 2.動物における病原体による腸感染の予防または処置のための請求項1の使 用。 3.病原体が細菌である、請求項1記載の使用。 4.細菌がE.coliである、請求項3記載の使用。 5.細菌がSalmonella typhimuriumである、請求項3記載の使用。 6.細菌がHelicobacter pyloriである、請求項3記載の使用。 7.動物の体重増加促進のための表皮成長因子の使用。 8.動物の腸における免疫グロブリン吸収の増加のための表皮成長因子の使用 。 9.表皮成長因子が、動物の餌に存在する、請求項1、7または8のいずれか に記載の使用。 10.表皮成長因子を経口投与する、請求項1、7または8のいずれかに記載 の使用。 11.動物の体重増加を減少するための表皮成長因子の活性を阻害する薬剤の 使用。 12.動物の腸への物質の吸収を減少するための表皮成長因子の活性を阻害す る薬剤の使用。 13.薬剤がチロシンキナーゼ阻害剤である、請求項11または12記載の使 用。 14.チロシンキナーゼ阻害剤がチロホスチン51である、請求項11または 12記載の使用。 15.薬剤がEGFレセプターの遮断剤であるか、またはEGFシグナルカス ケードの阻害剤である、請求項11または12記載の使用。 16.物質が栄養物である、請求項12記載の使用。 17.物質が毒性物質である、請求項12記載の使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/438,901 US5753622A (en) | 1995-05-10 | 1995-05-10 | Use of epidermal growth factor as a gastrointestinal therapeutic agent |
US08/438,901 | 1995-05-10 | ||
PCT/CA1996/000291 WO1996035445A1 (en) | 1995-05-10 | 1996-05-09 | The use of epidermal growth factor as a gastrointestinal therapeutic agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH11505528A true JPH11505528A (ja) | 1999-05-21 |
JP3549541B2 JP3549541B2 (ja) | 2004-08-04 |
Family
ID=23742496
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP53362496A Expired - Fee Related JP3549541B2 (ja) | 1995-05-10 | 1996-05-09 | 胃腸治療剤としての表皮成長因子の使用 |
Country Status (13)
Country | Link |
---|---|
US (2) | US5753622A (ja) |
EP (3) | EP1479394B1 (ja) |
JP (1) | JP3549541B2 (ja) |
AT (3) | ATE278415T1 (ja) |
AU (1) | AU704675B2 (ja) |
CA (2) | CA2220434C (ja) |
DE (3) | DE69637002T2 (ja) |
DK (3) | DK1092437T3 (ja) |
ES (2) | ES2226681T3 (ja) |
HK (1) | HK1072894A1 (ja) |
NZ (2) | NZ307134A (ja) |
PT (1) | PT1479394E (ja) |
WO (1) | WO1996035445A1 (ja) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5753622A (en) * | 1995-05-10 | 1998-05-19 | University Technologies International, Inc. | Use of epidermal growth factor as a gastrointestinal therapeutic agent |
US5929051A (en) * | 1998-05-13 | 1999-07-27 | Carrington Laboratories, Inc. | Aloe pectins |
US7022683B1 (en) * | 1998-05-13 | 2006-04-04 | Carrington Laboratories, Inc. | Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation |
US6313103B1 (en) | 1998-05-13 | 2001-11-06 | Carrington Laboratories, Inc. | Pectic substance as a growth factor stabilizer |
US20060014684A1 (en) * | 2000-03-03 | 2006-01-19 | University Technologies International Inc. | Novel uses of EGF |
US7494669B2 (en) | 2001-02-28 | 2009-02-24 | Carrington Laboratories, Inc. | Delivery of physiological agents with in-situ gels comprising anionic polysaccharides |
US6967090B2 (en) * | 2001-05-18 | 2005-11-22 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food | Nucleic acid and protein sequences of bovine epidermal growth factor |
EP1441754A1 (en) * | 2001-10-26 | 2004-08-04 | University Technologies International Inc. | Use of egf to inhibit pathogenic infections of the urogenital tract |
CA2427190A1 (en) * | 2002-04-30 | 2003-10-30 | Alberta Research Council Inc. | Production of recombinant epidermal growth factor in plants |
DE60319822T2 (de) | 2002-06-19 | 2009-06-04 | Actogenix Nv | Verfahren und mittel zur erhöhung der darmabsorption |
JP2008514651A (ja) * | 2004-09-30 | 2008-05-08 | ユニバーシティー・テクノロジーズ・インターナショナル・インコーポレイテッド | 上皮増殖因子(egf)を含んで成る再水和組成物 |
US8703769B2 (en) * | 2005-07-15 | 2014-04-22 | The University Of North Carolina At Chapel Hill | Use of EGFR inhibitors to prevent or treat obesity |
EP3097924B1 (en) | 2005-11-29 | 2020-01-08 | Intrexon Actobiotics NV | Induction of mucosal tolerance to gliadin |
DK3351268T3 (da) * | 2007-01-25 | 2020-11-02 | Intrexon Actobiotics Nv | Behandling af immunsygdom ved mukosal indgivelse af antigener |
WO2010042821A1 (en) * | 2008-10-10 | 2010-04-15 | Nationwide Children's Hospital | Method of treating necrotizing enterocolitis using heparin binding epidermal growth factor |
CN102696887B (zh) * | 2012-06-20 | 2013-07-31 | 湖南海谷生物技术有限公司 | 一种具有营养保健促生长功能的饲料活性蛋粉及其生产方法 |
US11241480B2 (en) * | 2017-01-26 | 2022-02-08 | Washington University | Methods for modulation of dietary and microbial exposure with compositions comprising an EGFR ligand |
CN113813369B (zh) * | 2021-11-09 | 2023-09-22 | 浙江省农业科学院 | 用于预防/治疗仔猪肠道损伤的egf/mmt复合物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8409960D0 (en) * | 1984-04-17 | 1984-05-31 | Searle & Co | Therapeutic method |
ATE80307T1 (de) * | 1986-12-11 | 1992-09-15 | British Tech Group | Verbesserungen im gebrauch oder in bezug auf den gebrauch von egf. |
DE69223615T2 (de) * | 1992-07-06 | 1998-04-09 | Nestle Sa | Lactobacillus Acidophilus enthaltende Antigastritis-Mittel |
US5753622A (en) * | 1995-05-10 | 1998-05-19 | University Technologies International, Inc. | Use of epidermal growth factor as a gastrointestinal therapeutic agent |
-
1995
- 1995-05-10 US US08/438,901 patent/US5753622A/en not_active Expired - Lifetime
-
1996
- 1996-05-09 CA CA002220434A patent/CA2220434C/en not_active Expired - Fee Related
- 1996-05-09 PT PT04019831T patent/PT1479394E/pt unknown
- 1996-05-09 NZ NZ307134A patent/NZ307134A/en not_active IP Right Cessation
- 1996-05-09 NZ NZ501482A patent/NZ501482A/xx not_active IP Right Cessation
- 1996-05-09 DE DE69637002T patent/DE69637002T2/de not_active Expired - Fee Related
- 1996-05-09 DE DE69614377T patent/DE69614377T2/de not_active Expired - Fee Related
- 1996-05-09 ES ES00123426T patent/ES2226681T3/es not_active Expired - Lifetime
- 1996-05-09 EP EP04019831A patent/EP1479394B1/en not_active Expired - Lifetime
- 1996-05-09 AT AT00123426T patent/ATE278415T1/de not_active IP Right Cessation
- 1996-05-09 WO PCT/CA1996/000291 patent/WO1996035445A1/en active IP Right Grant
- 1996-05-09 DK DK00123426T patent/DK1092437T3/da active
- 1996-05-09 EP EP96913397A patent/EP0824357B1/en not_active Expired - Lifetime
- 1996-05-09 ES ES04019831T patent/ES2285320T3/es not_active Expired - Lifetime
- 1996-05-09 DK DK04019831T patent/DK1479394T3/da active
- 1996-05-09 JP JP53362496A patent/JP3549541B2/ja not_active Expired - Fee Related
- 1996-05-09 EP EP00123426A patent/EP1092437B1/en not_active Expired - Lifetime
- 1996-05-09 DK DK96913397T patent/DK0824357T3/da active
- 1996-05-09 CA CA2492724A patent/CA2492724C/en not_active Expired - Fee Related
- 1996-05-09 AT AT96913397T patent/ATE203912T1/de not_active IP Right Cessation
- 1996-05-09 AT AT04019831T patent/ATE357927T1/de not_active IP Right Cessation
- 1996-05-09 AU AU56411/96A patent/AU704675B2/en not_active Ceased
- 1996-05-09 DE DE69633583T patent/DE69633583T2/de not_active Expired - Fee Related
-
2000
- 2000-03-03 US US09/518,135 patent/US6656907B1/en not_active Expired - Fee Related
-
2005
- 2005-05-24 HK HK05104375A patent/HK1072894A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69637002T2 (de) | 2007-08-16 |
PT1479394E (pt) | 2007-04-30 |
US6656907B1 (en) | 2003-12-02 |
CA2492724A1 (en) | 1996-11-14 |
CA2220434C (en) | 2005-02-22 |
AU5641196A (en) | 1996-11-29 |
EP1479394B1 (en) | 2007-03-28 |
EP1479394A1 (en) | 2004-11-24 |
DE69614377D1 (de) | 2001-09-13 |
ATE278415T1 (de) | 2004-10-15 |
DK1479394T3 (da) | 2007-06-11 |
ES2226681T3 (es) | 2005-04-01 |
WO1996035445A1 (en) | 1996-11-14 |
DK1092437T3 (da) | 2005-01-31 |
NZ501482A (en) | 2004-12-24 |
US5753622A (en) | 1998-05-19 |
DK0824357T3 (da) | 2001-10-08 |
ES2285320T3 (es) | 2007-11-16 |
CA2492724C (en) | 2010-08-03 |
AU704675B2 (en) | 1999-04-29 |
ATE203912T1 (de) | 2001-08-15 |
DE69614377T2 (de) | 2002-05-23 |
EP1092437B1 (en) | 2004-10-06 |
CA2220434A1 (en) | 1996-11-14 |
JP3549541B2 (ja) | 2004-08-04 |
NZ307134A (en) | 2000-02-28 |
HK1072894A1 (en) | 2005-09-16 |
DE69637002D1 (de) | 2007-05-10 |
DE69633583T2 (de) | 2006-02-23 |
EP0824357B1 (en) | 2001-08-08 |
EP0824357A1 (en) | 1998-02-25 |
EP1092437A1 (en) | 2001-04-18 |
DE69633583D1 (de) | 2004-11-11 |
ATE357927T1 (de) | 2007-04-15 |
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