JPH11133015A - クロマトグラフピークの識別方法 - Google Patents
クロマトグラフピークの識別方法Info
- Publication number
- JPH11133015A JPH11133015A JP10207473A JP20747398A JPH11133015A JP H11133015 A JPH11133015 A JP H11133015A JP 10207473 A JP10207473 A JP 10207473A JP 20747398 A JP20747398 A JP 20747398A JP H11133015 A JPH11133015 A JP H11133015A
- Authority
- JP
- Japan
- Prior art keywords
- peak
- sample
- retention time
- standard
- peaks
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims abstract description 73
- 230000014759 maintenance of location Effects 0.000 claims abstract description 181
- 230000008569 process Effects 0.000 abstract description 9
- 238000004364 calculation method Methods 0.000 abstract description 7
- 238000002347 injection Methods 0.000 abstract description 7
- 239000007924 injection Substances 0.000 abstract description 7
- 239000000243 solution Substances 0.000 abstract 1
- 239000000523 sample Substances 0.000 description 251
- 150000001875 compounds Chemical class 0.000 description 21
- 239000007789 gas Substances 0.000 description 14
- 238000004587 chromatography analysis Methods 0.000 description 10
- 239000012159 carrier gas Substances 0.000 description 9
- 238000010586 diagram Methods 0.000 description 9
- 239000012530 fluid Substances 0.000 description 9
- 239000000203 mixture Substances 0.000 description 9
- 238000004458 analytical method Methods 0.000 description 8
- 238000004817 gas chromatography Methods 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- 238000004811 liquid chromatography Methods 0.000 description 5
- 238000000926 separation method Methods 0.000 description 5
- 238000013459 approach Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 238000013375 chromatographic separation Methods 0.000 description 4
- 230000005526 G1 to G0 transition Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 238000013519 translation Methods 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000010339 dilation Effects 0.000 description 2
- 238000000148 multi-dimensional chromatography Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- YUWBVKYVJWNVLE-UHFFFAOYSA-N [N].[P] Chemical compound [N].[P] YUWBVKYVJWNVLE-UHFFFAOYSA-N 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 239000000538 analytical sample Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000011210 chromatographic step Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 230000005264 electron capture Effects 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- KSNNEUZOAFRTDS-UHFFFAOYSA-N fominoben Chemical compound ClC=1C=CC=C(NC(=O)C=2C=CC=CC=2)C=1CN(C)CC(=O)N1CCOCC1 KSNNEUZOAFRTDS-UHFFFAOYSA-N 0.000 description 1
- 229960004594 fominoben Drugs 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 238000002329 infrared spectrum Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000001819 mass spectrum Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 238000004451 qualitative analysis Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8624—Detection of slopes or peaks; baseline correction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N2030/621—Detectors specially adapted therefor signal-to-noise ratio
- G01N2030/625—Detectors specially adapted therefor signal-to-noise ratio by measuring reference material, e.g. carrier without sample
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8624—Detection of slopes or peaks; baseline correction
- G01N30/8631—Peaks
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/899,420 US5905192A (en) | 1997-07-23 | 1997-07-23 | Method for identification of chromatographic peaks |
| US899,420 | 1997-07-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11133015A true JPH11133015A (ja) | 1999-05-21 |
| JPH11133015A5 JPH11133015A5 (OSRAM) | 2005-10-27 |
Family
ID=25410937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10207473A Pending JPH11133015A (ja) | 1997-07-23 | 1998-07-23 | クロマトグラフピークの識別方法 |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US5905192A (OSRAM) |
| JP (1) | JPH11133015A (OSRAM) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103439440A (zh) * | 2013-07-11 | 2013-12-11 | 中国食品药品检定研究院 | 一种高效液相色谱峰保留时间预测方法 |
| JP2019056620A (ja) * | 2017-09-21 | 2019-04-11 | 株式会社日立ハイテクサイエンス | クロマトグラフのデータ処理装置 |
| WO2020084738A1 (ja) * | 2018-10-25 | 2020-04-30 | 株式会社島津製作所 | 質量分析装置およびプログラム |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6415232B1 (en) * | 1998-09-10 | 2002-07-02 | Tosoh Corporation | Chromatogram analyzer |
| US6438499B1 (en) * | 1998-09-10 | 2002-08-20 | Tosoh Corporation | Chromatogram analyzer |
| JP3807306B2 (ja) * | 1999-09-27 | 2006-08-09 | 株式会社日立製作所 | クロマトデータ処理装置、クロマトデータ処理方法、及びクロマトグラフ分析装置 |
| US20030170734A1 (en) * | 2000-04-28 | 2003-09-11 | Stephen Williams | Multiplexed assays using electrophoretically separated molecular tags |
| EP1202049A1 (en) * | 2000-10-31 | 2002-05-02 | Genome Express | Method and apparatus for analyzing data files derived from emission spectra from fluorophore tagged nucleotides |
| US6816789B2 (en) * | 2001-04-19 | 2004-11-09 | Varian, Inc. | Method and system for analyzing chromatograms |
| AU2003226195A1 (en) * | 2002-04-02 | 2003-10-20 | Monogram Biosciences, Inc. | Multiplexed assays using electrophoretically separated molecular tags |
| US20050115837A1 (en) * | 2003-12-01 | 2005-06-02 | Dean Burgi | Analyte identification in transformed electropherograms |
| FI20055253L (fi) * | 2005-05-26 | 2006-11-27 | Valtion Teknillinen | Analyysitekniikoita nestekromatografiaa/massaspektrometriaa varten |
| FI20055254A7 (fi) * | 2005-05-26 | 2006-11-27 | Valtion Teknillinen Tutkimuskeskus | Analyysitekniikoita nestekromatografiaa/massaspektrometriaa varten |
| FI20055252A7 (fi) * | 2005-05-26 | 2006-11-27 | Valtion Teknillinen Tutkimuskeskus | Analyysitekniikoita nestekromatografiaa/massaspektrometriaa varten |
| US7475050B2 (en) * | 2005-06-02 | 2009-01-06 | Agilent Technologies, Inc. | Systems for developing analytical device methods |
| US7983852B2 (en) | 2008-10-21 | 2011-07-19 | Thermo Finnigan Llc | Methods of automated spectral peak detection and quantification without user input |
| EP2322922B1 (en) | 2009-08-26 | 2015-02-25 | Thermo Fisher Scientific (Bremen) GmbH | Method of improving the resolution of compounds eluted from a chromatography device |
| US8428889B2 (en) | 2010-10-07 | 2013-04-23 | Thermo Finnigan Llc | Methods of automated spectral peak detection and quantification having learning mode |
| US10527595B2 (en) * | 2011-06-01 | 2020-01-07 | Tsumura & Co. | Method of and apparatus for formulating multicomponent drug |
| CN102507817B (zh) * | 2011-11-23 | 2013-11-13 | 天津大学 | 预测多阶程序升温条件下伸舌色谱峰形的方法 |
| US10802000B2 (en) | 2013-03-15 | 2020-10-13 | Dionex Corporation | Method of calibrating a chromatography system |
| JP2016532881A (ja) * | 2013-10-09 | 2016-10-20 | スペクトロセンス リミテッド | 改変されたガスクロマトグラフィーのデータ分析のための方法およびシステム |
| US9804136B2 (en) | 2014-09-18 | 2017-10-31 | Dionex Corporation | Automated method of calibrating a chromatography system and analysis of a sample |
| CN108061776B (zh) * | 2016-11-08 | 2020-08-28 | 中国科学院大连化学物理研究所 | 一种用于液相色谱-质谱的代谢组学数据峰匹配方法 |
| US11244818B2 (en) | 2018-02-19 | 2022-02-08 | Agilent Technologies, Inc. | Method for finding species peaks in mass spectrometry |
| CN112630327B (zh) * | 2020-12-03 | 2023-04-07 | 武汉职业技术学院 | 一种肉苁蓉活性成分的快速检测方法 |
| CN113237985B (zh) * | 2021-03-24 | 2023-10-20 | 迈克医疗电子有限公司 | 血红蛋白中组分类型的确定方法、装置和计算机设备 |
| CN115950988B (zh) * | 2023-01-06 | 2026-01-09 | 杭州谱育科技发展有限公司 | 基于寻峰技术的色谱分析方法 |
| GB202405275D0 (en) * | 2024-04-12 | 2024-05-29 | Micromass Ltd | Correction of mass spectral data |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2245815A1 (de) * | 1972-09-19 | 1974-03-28 | Bodenseewerk Perkin Elmer Co | Verfahren und vorrichtung zur identifizierung und auswertung von peaks in chromatogrammen |
| US4468742A (en) * | 1981-03-17 | 1984-08-28 | The Regents Of University Of California | Microprocessor system for quantitative chromatographic data analysis |
| US4802102A (en) * | 1987-07-15 | 1989-01-31 | Hewlett-Packard Company | Baseline correction for chromatography |
| US4941101A (en) * | 1987-09-01 | 1990-07-10 | Hewlett-Packard Company | Method for analyzing chromatograms |
| US5121443A (en) * | 1989-04-25 | 1992-06-09 | Spectra-Physics, Inc. | Neural net system for analyzing chromatographic peaks |
| US5119315A (en) * | 1989-04-28 | 1992-06-02 | Amoco Corporation | Method of correlating a record of sample data with a record of reference data |
| JP2602366B2 (ja) * | 1991-02-18 | 1997-04-23 | 株式会社日立製作所 | クロマトグラフ装置 |
| US5347475A (en) * | 1991-09-20 | 1994-09-13 | Amoco Corporation | Method for transferring spectral information among spectrometers |
| JP2957802B2 (ja) * | 1992-05-19 | 1999-10-06 | 株式会社日立製作所 | クロマトグラフ装置 |
| US5699270A (en) * | 1995-06-23 | 1997-12-16 | Exxon Research And Engineering Company | Method for preparing lubrication oils (LAW232) |
-
1997
- 1997-07-23 US US08/899,420 patent/US5905192A/en not_active Expired - Lifetime
-
1998
- 1998-07-23 JP JP10207473A patent/JPH11133015A/ja active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103439440A (zh) * | 2013-07-11 | 2013-12-11 | 中国食品药品检定研究院 | 一种高效液相色谱峰保留时间预测方法 |
| JP2019056620A (ja) * | 2017-09-21 | 2019-04-11 | 株式会社日立ハイテクサイエンス | クロマトグラフのデータ処理装置 |
| WO2020084738A1 (ja) * | 2018-10-25 | 2020-04-30 | 株式会社島津製作所 | 質量分析装置およびプログラム |
| JPWO2020084738A1 (ja) * | 2018-10-25 | 2021-09-30 | 株式会社島津製作所 | 質量分析装置およびプログラム |
Also Published As
| Publication number | Publication date |
|---|---|
| US5905192A (en) | 1999-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
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| A621 | Written request for application examination |
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| A131 | Notification of reasons for refusal |
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| A602 | Written permission of extension of time |
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| A131 | Notification of reasons for refusal |
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| A02 | Decision of refusal |
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