JPH08502280A - 新規タキサン誘導体、それらの製造法及びそれらを含む製薬学的組成物 - Google Patents

新規タキサン誘導体、それらの製造法及びそれらを含む製薬学的組成物

Info

Publication number
JPH08502280A
JPH08502280A JP6509706A JP50970694A JPH08502280A JP H08502280 A JPH08502280 A JP H08502280A JP 6509706 A JP6509706 A JP 6509706A JP 50970694 A JP50970694 A JP 50970694A JP H08502280 A JPH08502280 A JP H08502280A
Authority
JP
Japan
Prior art keywords
group
carbon atoms
alkyl
general formula
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6509706A
Other languages
English (en)
Japanese (ja)
Inventor
ブルザ，ジヤン−ドミニク
コメルソン，アラン
ドプレ，ドミニク
ピユリカニ，ジヤン−ピエール
Original Assignee
ローン−プーラン・ロレ・ソシエテ・アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ローン−プーラン・ロレ・ソシエテ・アノニム filed Critical ローン−プーラン・ロレ・ソシエテ・アノニム
Publication of JPH08502280A publication Critical patent/JPH08502280A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/25—Reduction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
JP6509706A 1992-10-15 1993-10-13 新規タキサン誘導体、それらの製造法及びそれらを含む製薬学的組成物 Pending JPH08502280A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9212331A FR2697019B1 (fr) 1992-10-15 1992-10-15 Nouveaux dérivés du taxane, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR92/12331 1992-10-15
PCT/FR1993/001013 WO1994008984A1 (fr) 1992-10-15 1993-10-13 Nouveaux derives du taxane, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
JPH08502280A true JPH08502280A (ja) 1996-03-12

Family

ID=9434565

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6509706A Pending JPH08502280A (ja) 1992-10-15 1993-10-13 新規タキサン誘導体、それらの製造法及びそれらを含む製薬学的組成物

Country Status (15)

Country Link
EP (1) EP0664800A1 (enrdf_load_stackoverflow)
JP (1) JPH08502280A (enrdf_load_stackoverflow)
KR (1) KR950703551A (enrdf_load_stackoverflow)
AU (1) AU5339594A (enrdf_load_stackoverflow)
CA (1) CA2146765A1 (enrdf_load_stackoverflow)
CZ (1) CZ95895A3 (enrdf_load_stackoverflow)
FI (1) FI951789L (enrdf_load_stackoverflow)
FR (1) FR2697019B1 (enrdf_load_stackoverflow)
MX (1) MX9306227A (enrdf_load_stackoverflow)
NO (1) NO951283D0 (enrdf_load_stackoverflow)
PL (1) PL308361A1 (enrdf_load_stackoverflow)
SK (1) SK49995A3 (enrdf_load_stackoverflow)
TW (1) TW250480B (enrdf_load_stackoverflow)
WO (1) WO1994008984A1 (enrdf_load_stackoverflow)
ZA (1) ZA937558B (enrdf_load_stackoverflow)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US6011056A (en) * 1991-09-23 2000-01-04 Florida State University C9 taxane derivatives and pharmaceutical compositions containing them
US6495704B1 (en) 1991-09-23 2002-12-17 Florida State University 9-desoxotaxanes and process for the preparation of 9-desoxotaxanes
DK0687260T3 (da) * 1993-03-05 2003-06-10 Univ Florida State Fremgangsmåde til fremstillingen af 9-desoxotaxaner
US6710191B2 (en) 1993-03-05 2004-03-23 Florida State University 9β-hydroxytetracyclic taxanes
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
US5635531A (en) * 1996-07-08 1997-06-03 Bristol-Myers Squibb Company 3'-aminocarbonyloxy paclitaxels
US5773464A (en) * 1996-09-30 1998-06-30 Bristol-Myers Squibb Company C-10 epoxy taxanes
US5977386A (en) * 1996-12-24 1999-11-02 Bristol-Myers Squibb Company 6-thio-substituted paclitaxels
US5902822A (en) * 1997-02-28 1999-05-11 Bristol-Myers Squibb Company 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US6017935A (en) * 1997-04-24 2000-01-25 Bristol-Myers Squibb Company 7-sulfur substituted paclitaxels
CN1886400A (zh) * 2003-09-25 2006-12-27 泰普斯特医药公司 9,10－α,α－OH紫杉烷类似物及其制备方法
SI1664033T1 (sl) * 2003-09-25 2008-04-30 Tapestry Pharmaceuticals Inc Analogi 9,10-alfa,alfa-oh-taksana in postopki za proizvodnjo le-teh
US11786504B2 (en) 2006-09-28 2023-10-17 Tapestry Pharmaceuticals, Inc. Taxane analogs for the treatment of brain cancer
WO2008106621A1 (en) 2007-02-28 2008-09-04 Tapestry Pharmaceuticals, Inc Taxane analogs for the treatment of brain cancer
WO2008121476A1 (en) 2007-03-28 2008-10-09 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
US11873308B2 (en) 2006-11-06 2024-01-16 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
CN108158991A (zh) 2012-07-19 2018-06-15 富士胶片株式会社 含紫杉烷系活性成分的液体组合物、其制造方法及液体制剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene

Also Published As

Publication number Publication date
FI951789A0 (fi) 1995-04-13
EP0664800A1 (fr) 1995-08-02
FI951789A7 (fi) 1995-04-13
CA2146765A1 (fr) 1994-04-28
SK49995A3 (en) 1995-09-13
WO1994008984A1 (fr) 1994-04-28
FI951789L (fi) 1995-04-13
TW250480B (enrdf_load_stackoverflow) 1995-07-01
NO951283L (no) 1995-04-03
FR2697019B1 (fr) 1994-11-25
ZA937558B (en) 1994-05-04
PL308361A1 (en) 1995-07-24
NO951283D0 (no) 1995-04-03
AU5339594A (en) 1994-05-09
FR2697019A1 (fr) 1994-04-22
CZ95895A3 (en) 1995-09-13
MX9306227A (es) 1994-05-31
KR950703551A (ko) 1995-09-20

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