JPH0820545A - 改良された性質を有する抗体コンジュゲート - Google Patents

改良された性質を有する抗体コンジュゲート

Info

Publication number
JPH0820545A
JPH0820545A JP7059022A JP5902295A JPH0820545A JP H0820545 A JPH0820545 A JP H0820545A JP 7059022 A JP7059022 A JP 7059022A JP 5902295 A JP5902295 A JP 5902295A JP H0820545 A JPH0820545 A JP H0820545A
Authority
JP
Japan
Prior art keywords
antibody
carrier protein
conjugate
conjugate according
conjugates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7059022A
Other languages
English (en)
Japanese (ja)
Inventor
Brendan Murray
ムーライ ブレンダン
Reilly Terence O
オライリー テレンス
Gerd Pluschke
プルシュケ ゲルト
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPH0820545A publication Critical patent/JPH0820545A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6415—Toxins or lectins, e.g. clostridial toxins or Pseudomonas exotoxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
JP7059022A 1994-03-21 1995-03-17 改良された性質を有する抗体コンジュゲート Pending JPH0820545A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE94810173:8 1994-03-21
EP94810173 1994-03-21

Publications (1)

Publication Number Publication Date
JPH0820545A true JPH0820545A (ja) 1996-01-23

Family

ID=8218230

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7059022A Pending JPH0820545A (ja) 1994-03-21 1995-03-17 改良された性質を有する抗体コンジュゲート

Country Status (11)

Country Link
JP (1) JPH0820545A (hu)
KR (1) KR950031111A (hu)
AU (1) AU1481795A (hu)
CA (1) CA2144936A1 (hu)
FI (1) FI951276A (hu)
HU (1) HUT71776A (hu)
IL (1) IL113022A (hu)
NO (1) NO951061L (hu)
NZ (1) NZ270734A (hu)
RU (1) RU95104325A (hu)
ZA (1) ZA952269B (hu)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007520612A (ja) * 2004-02-03 2007-07-26 アンタイス エス．エイ． 生体適合性架橋ゲル

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007520612A (ja) * 2004-02-03 2007-07-26 アンタイス エス．エイ． 生体適合性架橋ゲル

Also Published As

Publication number Publication date
RU95104325A (ru) 1996-12-27
KR950031111A (ko) 1995-12-18
FI951276A (fi) 1995-09-22
IL113022A0 (en) 1995-06-29
IL113022A (en) 2000-02-29
CA2144936A1 (en) 1995-09-22
AU1481795A (en) 1995-09-28
NO951061D0 (no) 1995-03-20
FI951276A0 (fi) 1995-03-17
HU9500586D0 (en) 1995-04-28
ZA952269B (en) 1995-09-21
HUT71776A (en) 1996-01-29
NO951061L (no) 1995-09-22
NZ270734A (en) 1997-05-26

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