JPH07508646A - 網膜の色素沈着された上皮由来の神経栄養性因子 - Google Patents
網膜の色素沈着された上皮由来の神経栄養性因子Info
- Publication number
- JPH07508646A JPH07508646A JP6500883A JP50088394A JPH07508646A JP H07508646 A JPH07508646 A JP H07508646A JP 6500883 A JP6500883 A JP 6500883A JP 50088394 A JP50088394 A JP 50088394A JP H07508646 A JPH07508646 A JP H07508646A
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- Prior art keywords
- pednf
- ammonium sulfate
- protein
- cells
- medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89421592A | 1992-06-04 | 1992-06-04 | |
| US894,215 | 1992-06-04 | ||
| PCT/US1993/005358 WO1993024529A1 (en) | 1992-06-04 | 1993-06-04 | Retinal pigmented epithelium derived neurotrophic factor |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004171939A Division JP2004262947A (ja) | 1992-06-04 | 2004-06-09 | 網膜の色素沈着された上皮由来の神経栄養性因子 |
| JP2005005788A Division JP2005112863A (ja) | 1992-06-04 | 2005-01-12 | 網膜の色素沈着された上皮由来の神経栄養性因子 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH07508646A true JPH07508646A (ja) | 1995-09-28 |
Family
ID=25402767
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6500883A Withdrawn JPH07508646A (ja) | 1992-06-04 | 1993-06-04 | 網膜の色素沈着された上皮由来の神経栄養性因子 |
| JP2004171939A Pending JP2004262947A (ja) | 1992-06-04 | 2004-06-09 | 網膜の色素沈着された上皮由来の神経栄養性因子 |
| JP2005005788A Withdrawn JP2005112863A (ja) | 1992-06-04 | 2005-01-12 | 網膜の色素沈着された上皮由来の神経栄養性因子 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004171939A Pending JP2004262947A (ja) | 1992-06-04 | 2004-06-09 | 網膜の色素沈着された上皮由来の神経栄養性因子 |
| JP2005005788A Withdrawn JP2005112863A (ja) | 1992-06-04 | 2005-01-12 | 網膜の色素沈着された上皮由来の神経栄養性因子 |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP1415994A1 (enExample) |
| JP (3) | JPH07508646A (enExample) |
| AU (1) | AU4406993A (enExample) |
| CA (1) | CA2137377C (enExample) |
| DE (1) | DE69333229T2 (enExample) |
| WO (1) | WO1993024529A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006046584A1 (ja) * | 2004-10-26 | 2006-05-04 | Santen Pharmaceutical Co., Ltd. | 視細胞障害治療剤 |
| JP2022524094A (ja) * | 2019-03-04 | 2022-04-27 | キュアビオテック・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 色素上皮由来因子（ｐｅｄｆ）を使用する疾患の処置のための方法 |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5840686A (en) * | 1992-09-24 | 1998-11-24 | The United States Of America As Represented By The Department Of Health And Human Services | Pigment epithelium-derived factor: characterization of its novel biological activity and sequences encoding and expressing the protein and methods of use |
| US6451763B1 (en) | 1992-06-04 | 2002-09-17 | The United States Of America As Represented By The Department Of Health And Human Services | Retinal pigmented epithelium derived neurotrophic factor and methods of use |
| US6319687B1 (en) * | 1992-09-24 | 2001-11-20 | The United States Of America As Represented By The Department Of Health And Human Services | Pigment epithelium-derived factor: characterization, genomic organization and sequence of PEDF gene |
| US6472585B1 (en) | 1994-04-25 | 2002-10-29 | Genentech, Inc. | Cardiotrophin-1 defective mouse |
| US7258983B2 (en) | 1994-04-25 | 2007-08-21 | Genentech, Inc. | Cardiotrophin-1 compositions and methods for the treatment of tumor |
| EP0755446B1 (en) * | 1994-04-25 | 2006-09-13 | Genentech, Inc. | Cardiotrophin and uses therefor |
| US5534615A (en) * | 1994-04-25 | 1996-07-09 | Genentech, Inc. | Cardiac hypertrophy factor and uses therefor |
| US5804376A (en) * | 1995-05-02 | 1998-09-08 | Incyte Pharmaceuticals, Inc. | Pancreas-derived serpin |
| US7105496B2 (en) | 1998-07-23 | 2006-09-12 | Northwestern University | Methods and compositions for inhibiting angiogenesis |
| US6797691B1 (en) | 1997-07-23 | 2004-09-28 | Northwestern University | Methods and compositions for inhibiting angiogenesis |
| JP2001510804A (ja) | 1997-07-23 | 2001-08-07 | ノースウエスタン・ユニバーシテイ | 血管新生を阻害するための方法及び組成物 |
| US6821775B1 (en) | 2000-02-11 | 2004-11-23 | Genvec, Inc. | Viral vector encoding pigment epithelium-derived factor |
| JP2004516001A (ja) * | 2000-02-23 | 2004-06-03 | ノースウエスタン・ユニバーシテイ | 新脈管形成を阻害するための方法および組成物 |
| US20030158112A1 (en) | 2002-02-15 | 2003-08-21 | Johns Hopkins University School Of Medicine | Selective induction of apoptosis to treat ocular disease |
| US20040166091A1 (en) | 2003-02-24 | 2004-08-26 | Genvec, Inc. | Materials and methods for treating disorders of the ear |
| US8173591B2 (en) | 2004-11-16 | 2012-05-08 | Yeda Research And Development Co. | Variants of pigment epithelium derived factor and uses thereof |
| WO2006064512A1 (en) * | 2004-12-13 | 2006-06-22 | Unichem Laboratories Limited | A process of fractionating and storing proteins |
| CA2629519A1 (en) | 2005-11-14 | 2007-05-18 | Yeda Research & Development Co. Ltd. At The Weizmann Institute Of Scienc E | Improved variants of pigment epithelium derived factor and uses thereof |
| JP2015529669A (ja) * | 2012-09-17 | 2015-10-08 | マクカイ メモリアル ホスピタル | 脱毛症及び／又は毛髪色素脱失を治療するためのｐｅｄｆ由来のポリペプチドの使用 |
| TWI710635B (zh) | 2014-10-09 | 2020-11-21 | 美商珍維克公司 | 編碼人類無調同源物-1(hath1)之腺病毒載體 |
| JP6522063B2 (ja) * | 2017-08-10 | 2019-05-29 | マクカイ メモリアル ホスピタル | 脱毛症及び／又は毛髪色素脱失を治療するためのｐｅｄｆ由来のポリペプチドの使用 |
| TWI840415B (zh) * | 2018-09-27 | 2024-05-01 | 加州大學董事會 | 用於基於細胞之療法或治療的檢定 |
| WO2021118924A2 (en) | 2019-12-12 | 2021-06-17 | Ting Therapeutics Llc | Compositions and methods for the prevention and treatment of hearing loss |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5229500A (en) * | 1989-08-30 | 1993-07-20 | Regeneron Pharmaceuticals, Inc. | Brain derived neurotrophic factor |
-
1993
- 1993-06-04 WO PCT/US1993/005358 patent/WO1993024529A1/en not_active Ceased
- 1993-06-04 AU AU44069/93A patent/AU4406993A/en not_active Abandoned
- 1993-06-04 DE DE69333229T patent/DE69333229T2/de not_active Expired - Lifetime
- 1993-06-04 JP JP6500883A patent/JPH07508646A/ja not_active Withdrawn
- 1993-06-04 CA CA2137377A patent/CA2137377C/en not_active Expired - Lifetime
- 1993-06-04 EP EP20030022103 patent/EP1415994A1/en not_active Ceased
- 1993-06-04 EP EP93914393A patent/EP0662087B1/en not_active Expired - Lifetime
-
2004
- 2004-06-09 JP JP2004171939A patent/JP2004262947A/ja active Pending
-
2005
- 2005-01-12 JP JP2005005788A patent/JP2005112863A/ja not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006046584A1 (ja) * | 2004-10-26 | 2006-05-04 | Santen Pharmaceutical Co., Ltd. | 視細胞障害治療剤 |
| JP2022524094A (ja) * | 2019-03-04 | 2022-04-27 | キュアビオテック・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 色素上皮由来因子（ｐｅｄｆ）を使用する疾患の処置のための方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2137377C (en) | 2011-03-08 |
| CA2137377A1 (en) | 1993-12-09 |
| EP1415994A1 (en) | 2004-05-06 |
| DE69333229D1 (de) | 2003-11-06 |
| EP0662087A1 (en) | 1995-07-12 |
| JP2004262947A (ja) | 2004-09-24 |
| WO1993024529A1 (en) | 1993-12-09 |
| EP0662087A4 (en) | 1997-01-29 |
| JP2005112863A (ja) | 2005-04-28 |
| AU4406993A (en) | 1993-12-30 |
| DE69333229T2 (de) | 2004-08-12 |
| EP0662087B1 (en) | 2003-10-01 |
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