JPH07503462A - カルシウムチャンネル拮抗薬としてのアザビシクロ化合物 - Google Patents
カルシウムチャンネル拮抗薬としてのアザビシクロ化合物Info
- Publication number
- JPH07503462A JPH07503462A JP5513048A JP51304893A JPH07503462A JP H07503462 A JPH07503462 A JP H07503462A JP 5513048 A JP5513048 A JP 5513048A JP 51304893 A JP51304893 A JP 51304893A JP H07503462 A JPH07503462 A JP H07503462A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- azabicyclo
- heptane
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929201751A GB9201751D0 (en) | 1992-01-28 | 1992-01-28 | Compounds |
GB9201751.6 | 1992-01-28 | ||
PCT/GB1993/000174 WO1993015080A1 (en) | 1992-01-28 | 1993-01-27 | Azabicyclo compounds as calcium channel antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH07503462A true JPH07503462A (ja) | 1995-04-13 |
Family
ID=10709351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5513048A Pending JPH07503462A (ja) | 1992-01-28 | 1993-01-27 | カルシウムチャンネル拮抗薬としてのアザビシクロ化合物 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0625981A1 (de) |
JP (1) | JPH07503462A (de) |
KR (1) | KR950700305A (de) |
AU (1) | AU3364593A (de) |
CA (1) | CA2128536A1 (de) |
GB (1) | GB9201751D0 (de) |
MX (1) | MX9300406A (de) |
WO (1) | WO1993015080A1 (de) |
ZA (1) | ZA93549B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9314973D0 (en) * | 1993-07-20 | 1993-09-01 | Smithkline Beecham Plc | Medicaments |
UY25225A1 (es) | 1997-10-29 | 2000-12-29 | Smithkline Beecham Plc | Derivados de pleuromutilina utiles como agentes antimicrobianos |
AU1600599A (en) | 1998-02-27 | 1999-09-15 | Warner-Lambert Company | Heterocyclic substituted aniline calcium channel blockers |
US6166052A (en) * | 1998-03-11 | 2000-12-26 | Warner-Lambert Company | Heteroaryl alkyl alpha substituted peptidylamine calcium channel blockers |
CA2441896A1 (en) | 2000-12-22 | 2002-07-04 | Almirall Prodesfarma Ag | Quinuclidine carbamate derivatives and their use as m3 antagonists |
ES2203327B1 (es) | 2002-06-21 | 2005-06-16 | Almirall Prodesfarma, S.A. | Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen. |
ES2204295B1 (es) | 2002-07-02 | 2005-08-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de quinuclidina-amida. |
WO2009046025A1 (en) | 2007-10-01 | 2009-04-09 | Comentis, Inc. | Quinuclidin-4-ylmethyl 1h-indole-3-carboxylate derivatives as alpha 7 nicotinic acetylcholine receptor ligands for the treatment of alzheimer's disease |
WO2016007630A1 (en) | 2014-07-11 | 2016-01-14 | Alpharmagen, Llc | Quinuclidine compounds for modulating alpha7 -nicotinic acetylcholine receptor activity |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1250534A (de) * | 1969-03-03 | 1971-10-20 | ||
GB9005737D0 (en) * | 1990-03-14 | 1990-05-09 | Beecham Group Plc | Novel compounds |
-
1992
- 1992-01-28 GB GB929201751A patent/GB9201751D0/en active Pending
-
1993
- 1993-01-26 MX MX9300406A patent/MX9300406A/es unknown
- 1993-01-26 ZA ZA93549A patent/ZA93549B/xx unknown
- 1993-01-27 CA CA002128536A patent/CA2128536A1/en not_active Abandoned
- 1993-01-27 WO PCT/GB1993/000174 patent/WO1993015080A1/en not_active Application Discontinuation
- 1993-01-27 AU AU33645/93A patent/AU3364593A/en not_active Abandoned
- 1993-01-27 EP EP93902470A patent/EP0625981A1/de not_active Withdrawn
- 1993-01-27 JP JP5513048A patent/JPH07503462A/ja active Pending
-
1994
- 1994-07-27 KR KR1019940702589A patent/KR950700305A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR950700305A (ko) | 1995-01-16 |
CA2128536A1 (en) | 1993-08-05 |
AU3364593A (en) | 1993-09-01 |
WO1993015080A1 (en) | 1993-08-05 |
EP0625981A1 (de) | 1994-11-30 |
ZA93549B (en) | 1994-09-22 |
GB9201751D0 (en) | 1992-03-11 |
MX9300406A (es) | 1994-07-29 |
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