JPH0749430B2 - ヘテロ環置換ナフチリジノン並びにそれらの使用方法および組成物 - Google Patents

ヘテロ環置換ナフチリジノン並びにそれらの使用方法および組成物

Info

Publication number
JPH0749430B2
JPH0749430B2 JP3501526A JP50152691A JPH0749430B2 JP H0749430 B2 JPH0749430 B2 JP H0749430B2 JP 3501526 A JP3501526 A JP 3501526A JP 50152691 A JP50152691 A JP 50152691A JP H0749430 B2 JPH0749430 B2 JP H0749430B2
Authority
JP
Japan
Prior art keywords
compounds
formula
compound
reaction
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP3501526A
Other languages
English (en)
Japanese (ja)
Other versions
JPH04506357A (ja
Inventor
ブリシン,デービッド・ジェイ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of JPH04506357A publication Critical patent/JPH04506357A/ja
Publication of JPH0749430B2 publication Critical patent/JPH0749430B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP3501526A 1989-12-04 1990-11-30 ヘテロ環置換ナフチリジノン並びにそれらの使用方法および組成物 Expired - Lifetime JPH0749430B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44558789A 1989-12-04 1989-12-04
US445,587 1989-12-04
PCT/US1990/006873 WO1991008208A1 (fr) 1989-12-04 1990-11-30 Naphtyridinones substituees heterocycliques, procedes et compositions les employant

Publications (2)

Publication Number Publication Date
JPH04506357A JPH04506357A (ja) 1992-11-05
JPH0749430B2 true JPH0749430B2 (ja) 1995-05-31

Family

ID=23769494

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3501526A Expired - Lifetime JPH0749430B2 (ja) 1989-12-04 1990-11-30 ヘテロ環置換ナフチリジノン並びにそれらの使用方法および組成物

Country Status (5)

Country Link
EP (1) EP0505434A1 (fr)
JP (1) JPH0749430B2 (fr)
AU (1) AU6960391A (fr)
CA (1) CA2070400A1 (fr)
WO (1) WO1991008208A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2654104B1 (fr) * 1989-11-07 1992-01-03 Adir Nouveaux derives du 1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5663781A (en) * 1979-10-12 1981-05-30 Eriksson Lars Clamp for connecting cable to battery terminal
JPS6231946A (ja) * 1985-07-02 1987-02-10 ガ−ニツク マジスヤン クランプ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ218774A (en) * 1986-01-06 1990-06-26 Carpibem 3-substituted phenylnaphthyridines and pharmaceutical compositions
JPH07116187B2 (ja) * 1987-07-22 1995-12-13 シェリング・コーポレーション 二環式化合物、それらを薬剤として使用すること、それらの製法、およびそれらの製造に有用な中間体

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5663781A (en) * 1979-10-12 1981-05-30 Eriksson Lars Clamp for connecting cable to battery terminal
JPS6231946A (ja) * 1985-07-02 1987-02-10 ガ−ニツク マジスヤン クランプ

Also Published As

Publication number Publication date
JPH04506357A (ja) 1992-11-05
EP0505434A1 (fr) 1992-09-30
CA2070400A1 (fr) 1991-06-05
WO1991008208A1 (fr) 1991-06-13
AU6960391A (en) 1991-06-26

Similar Documents

Publication Publication Date Title
US4492702A (en) 1-Phenyl-1,8-naphthridin-2(1H)-ones
EP0268989B1 (fr) Composés d'imidazopyridine et leurs procédés de préparation
US4902693A (en) Anti-allergic esters, acetal ethers, thioethers and nitrogen substituted derivatives of bicyclic compounds
JPS63246372A (ja) 3−ヘテロ置換−n−ベンジル−インドール
JPH0276855A (ja) キノリンエーテルアルカン酸
JPH0415786B2 (fr)
JP3004566B2 (ja) 新規な(チア)シクロアルキル〔b〕インドール類、それらの製造法及びそれらを含む医薬組成物
EP0318084A2 (fr) Benzohétérazoles
JPH0568476B2 (fr)
PL119501B1 (en) Process for manufacturing novel,condensed pyrimidine derivatives pirimidina
EP0318083A2 (fr) Acides pyridyl-dialkanoides et leur utilisation comme médicaments
JPH072770A (ja) 新規な置換インドール類、その製造法及びそのインドール類を含有する製剤組成物
PT92180B (pt) Processo para a preparacao de novas mevalonolactonas do tipo tienopiridina e de composicoes farmaceuticas que as contem
KR900006118B1 (ko) 4-퀴놀론 유도체의 제법
US4628055A (en) Method for treating allergic reactions and compositions therefore
JPH06199866A (ja) ジアゼピン誘導体
JPH07278148A (ja) イミダゾピラゾール誘導体
HUT71352A (en) Heterocyclic derivatives
JPH0749430B2 (ja) ヘテロ環置換ナフチリジノン並びにそれらの使用方法および組成物
AU632461B2 (en) Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
EP0198633A2 (fr) Dérivés de pyridine
US5760034A (en) Heterocyclic substituted naphthyridinones and methods and compositions employing them
JPS63159382A (ja) 1−置換ナフチリジンおよびピリドピラジン誘導体
JPS604170A (ja) キノロン誘導体
JPH02111759A (ja) ヘテラゾールジアルカン酸類

Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20071127

Year of fee payment: 9

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20071127

Year of fee payment: 9

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20071127

Year of fee payment: 9

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20081127

Year of fee payment: 10

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20081127

Year of fee payment: 10

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20091127

Year of fee payment: 11

EXPY Cancellation because of completion of term