NZ218774A - 3-substituted phenylnaphthyridines and pharmaceutical compositions - Google Patents
3-substituted phenylnaphthyridines and pharmaceutical compositionsInfo
- Publication number
- NZ218774A NZ218774A NZ218774A NZ21877486A NZ218774A NZ 218774 A NZ218774 A NZ 218774A NZ 218774 A NZ218774 A NZ 218774A NZ 21877486 A NZ21877486 A NZ 21877486A NZ 218774 A NZ218774 A NZ 218774A
- Authority
- NZ
- New Zealand
- Prior art keywords
- functional group
- phenylnaphthyridines
- substituted
- esterified
- meta
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Abstract
Phenylnaphthyridines functionalised in position 3, of formula: <IMAGE> in which: X and Y denote the hydrogen atom, a halogen, a lower alkyl group containing 1 to 5 carbon atoms, trifluoromethyl, an alkoxy, methylthio, nitro or cyano and may be in an ortho, meta or para position in the aromatic ring, preferably in a meta or para position Z is a functional group which may contain: - an unsaturation - an alkylthio functional group substituted or otherwise by guanidine, urea or nitrodiaminoethene derivatives - an alkylsulphinyl functional group - an ether functional group - an alcohol functional group, esterified or otherwise - a ketone functional group - an acidic functional group, esterified or otherwise - a halogen - a cyano functional group - an amine functional group - an aminoacid or amidoacid functional group - a phosphorylated functional group - an aromatic or heteroaromatic nucleus and medications containing one of these derivatives or optionally one of their nontoxic addition salts with acids.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8600102A FR2592649B1 (en) | 1986-01-06 | 1986-01-06 | CYANO AND AMIDO PHENYL-NAPHTYRIDINES, THEIR PREPARATION PROCESS, MEDICAMENTS CONTAINING THEM, IN PARTICULAR ANTI-ULCERS. |
FR8600105A FR2592652B1 (en) | 1986-01-06 | 1986-01-06 | NOVEL PHENYL-NAPHTYRIDINES, THEIR PREPARATION PROCESS AND THE MEDICINAL PRODUCTS CONTAINING THEM. |
FR8600103A FR2592650B1 (en) | 1986-01-06 | 1986-01-06 | NOVEL PHENYL-NAPHTYRIDINES FUNCTIONALIZED IN POSITION-3, THEIR PREPARATION PROCESS, MEDICAMENTS CONTAINING THEM, IN PARTICULAR ANTI-ULCERS. |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ218774A true NZ218774A (en) | 1990-06-26 |
Family
ID=27251327
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ218774A NZ218774A (en) | 1986-01-06 | 1986-12-23 | 3-substituted phenylnaphthyridines and pharmaceutical compositions |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0231709B1 (en) |
KR (1) | KR900004830B1 (en) |
AT (1) | ATE78478T1 (en) |
AU (1) | AU592396B2 (en) |
DE (1) | DE3686149T2 (en) |
DK (1) | DK2787A (en) |
ES (1) | ES2042506T3 (en) |
GR (1) | GR3005730T3 (en) |
NZ (1) | NZ218774A (en) |
PH (1) | PH24700A (en) |
PT (1) | PT84049B (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ218773A (en) * | 1986-01-06 | 1990-05-28 | Carpibem | 3-methyl-2-oxo-1-(substituted phenyl)-naphthyridines and pharmaceutical compositions |
US4916131A (en) * | 1986-10-15 | 1990-04-10 | Schering Corporation | Naphthyridine derivatives and method for treating allergic reactions |
US5037826A (en) * | 1986-10-15 | 1991-08-06 | Schering Corporation | 1-substituted naphthyridine and pyridopyrazine derivatives |
EP0267691A3 (en) * | 1986-10-15 | 1989-08-23 | Schering Corporation | Use of 1-substituted naphthyridine and pyridopyrazine derivatives for the preparation of medicaments with immunosuppressor activity. |
US4775686A (en) * | 1986-10-15 | 1988-10-04 | Schering Corporation | Naphthyridine derivatives and method for treating allergic reactions |
JPH07116187B2 (en) * | 1987-07-22 | 1995-12-13 | シェリング・コーポレーション | Bicyclic compounds, their use as pharmaceuticals, processes for their preparation, and intermediates useful in their manufacture |
WO1991008208A1 (en) * | 1989-12-04 | 1991-06-13 | Schering Corporation | Heterocyclic substituted naphthyridinones and methods and compositions employing them |
US5760034A (en) * | 1990-11-30 | 1998-06-02 | Schering Corporation | Heterocyclic substituted naphthyridinones and methods and compositions employing them |
JPH1171351A (en) * | 1997-08-29 | 1999-03-16 | Ss Pharmaceut Co Ltd | Substituted quinolone derivative and medicine containing the same |
US7115623B2 (en) * | 2001-06-12 | 2006-10-03 | Aska Pharmaceuticals Co., Ltd. | PDE IV inhibitors |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4133885A (en) * | 1977-07-18 | 1979-01-09 | Merck & Co., Inc. | Substituted naphthyridinones |
US4324893A (en) * | 1979-04-18 | 1982-04-13 | American Home Products Corporation | 4-Amino-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives |
US4215123A (en) * | 1979-05-07 | 1980-07-29 | American Home Products Corporation | Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives |
FR2567520B1 (en) * | 1984-07-11 | 1987-01-02 | Carpibem | NOVEL PHENYL-NAPHTHYRIDINES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, IN PARTICULAR ANTI-ULCERS |
NZ218773A (en) * | 1986-01-06 | 1990-05-28 | Carpibem | 3-methyl-2-oxo-1-(substituted phenyl)-naphthyridines and pharmaceutical compositions |
-
1986
- 1986-12-23 NZ NZ218774A patent/NZ218774A/en unknown
- 1986-12-24 AU AU67023/86A patent/AU592396B2/en not_active Ceased
- 1986-12-29 ES ES86402949T patent/ES2042506T3/en not_active Expired - Lifetime
- 1986-12-29 EP EP86402949A patent/EP0231709B1/en not_active Expired - Lifetime
- 1986-12-29 DE DE8686402949T patent/DE3686149T2/en not_active Expired - Fee Related
- 1986-12-29 AT AT86402949T patent/ATE78478T1/en not_active IP Right Cessation
- 1986-12-30 KR KR1019860011598A patent/KR900004830B1/en not_active IP Right Cessation
-
1987
- 1987-01-02 PT PT84049A patent/PT84049B/en not_active IP Right Cessation
- 1987-01-05 DK DK002787A patent/DK2787A/en not_active Application Discontinuation
- 1987-01-06 PH PH34691A patent/PH24700A/en unknown
-
1992
- 1992-09-17 GR GR920402053T patent/GR3005730T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0231709B1 (en) | 1992-07-22 |
KR870007167A (en) | 1987-08-17 |
ES2042506T3 (en) | 1993-12-16 |
DK2787A (en) | 1987-07-07 |
DE3686149T2 (en) | 1993-02-18 |
AU592396B2 (en) | 1990-01-11 |
ATE78478T1 (en) | 1992-08-15 |
DE3686149D1 (en) | 1992-08-27 |
EP0231709A2 (en) | 1987-08-12 |
EP0231709A3 (en) | 1988-11-02 |
PT84049A (en) | 1987-02-01 |
PT84049B (en) | 1989-02-28 |
GR3005730T3 (en) | 1993-06-07 |
PH24700A (en) | 1990-10-01 |
DK2787D0 (en) | 1987-01-05 |
AU6702386A (en) | 1987-07-09 |
KR900004830B1 (en) | 1990-07-07 |
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