JPH07101832A - Hair-tonic cosmetic - Google Patents

Abstract

PURPOSE:To provide a hair-tonic cosmetic having excellent hairtonic, hair- growing, falling-off preventing and dandruffpreventing effects, etc. CONSTITUTION:This cosmetic is produced by compounding at least one kind of gamma-amino-beta-hydroxybutyric acid and its salt and at least one kind of swertia extract or dihydric alcohol.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a hair nourishing cosmetic composition which activates hair mother cells, and has excellent hair-growth and hair-growth effects, hair loss prevention, and dandruff prevention.

[0002]

BACKGROUND OF THE INVENTION Conventionally, hair nourishing cosmetics containing scalp blood circulation promoting substances such as capsicum tincture, nicotinic acid, methyl nicotinate, cembly extract and Korean carrot extract have been known. Has been.
However, these blood circulation-promoting substances have strong skin irritation and the amount of the mixture is limited, or the blood circulation-promoting action is reduced in a short time or the blood circulation-promoting action is weak. The effects of hair growth, hair loss prevention, dandruff prevention, etc. have not been fully achieved. An object of the present invention is to provide a hair nourishing cosmetic that continuously promotes blood circulation in the scalp and is excellent in effects such as hair growth, hair loss prevention and dandruff prevention.

[0003]

The inventors of the present invention have conducted extensive studies to achieve the above object, and as a result, γ-
A hair nourishing cosmetic composition comprising at least one kind of amino-β-hydroxybutyric acid and a salt thereof, a combination extract and at least one kind of dihydric alcohol, is further used for the effects of hair nourishment, hair loss prevention, dandruff prevention, etc. They have found that they are excellent and have completed the present invention.

It is known that γ-amino-β-hydroxybutyric acid and salts thereof incorporated in the present invention have a hair mother cell activating effect. In addition, the assembly extract is a known substance, and is known to have a blood circulation promoting action. The dihydric alcohol used in the present invention is a compound having two hydroxyl groups in the molecule, such as ethylene glycol, triethylene glycol, propylene glycol, 1,3-butylene glycol, dipropylene glycol, polyethylene glycol, and polypropylene glycol. Etc. Conventionally, the above dihydric alcohol has been used in cosmetics as a moisturizer, a softener, and a thickener. However, in the present invention, the above-mentioned γ-amino-β-hydroxybutyric acid and a salt thereof, assembly extract, and dihydric alcohol are used in combination to synergistically exhibit the hair-restoration and hair loss prevention effects aimed at by the present invention, and Found that the scalp metabolic function is normalized to enhance the dandruff prevention effect, and completed the present invention.

The inventor of the present invention has investigated the blending ratio that maximizes the synergistic effect of the above-mentioned constituents to be blended in the hair nourishing cosmetic, and as a result, (1) γ-amino-β-hydroxybutyric acid and its salt, The ratio (weight ratio) of the blending amounts of (2) assembly extract and (3) dihydric alcohol is (1) +
The case (2) :( 3) = 1: 1 to 1:10 is preferable, and the excellent effect aimed at by the present invention was recognized. Further, the blending amount in the hair nourishing cosmetic of (1) is
0.01 to 1.0% by weight (hereinafter, w
(abbreviated as t%) and (2) are preferably 1.0 to 5.0 wt%. If the amount is less than the lower limit of each compounding amount and other than the compounding ratio, the effect aimed at by the present invention is not sufficient, while if it exceeds the upper limit, the improvement of the effect commensurate with the increased amount cannot be expected.

Although the method for producing assembly extract is not specified, in the present invention, the assembly extract produced as described below was applied. [Method for producing assembly extract] Assembly (Swertia
This is an extract obtained by digesting a dry pulverized product of whole flowering plants of (Japana Makino) in ethanol or hydrous ethanol and filtering. The extract obtained by the following method was applied to Examples and Comparative Examples described below.

50 g of the ground product of Assemblies were digested with 250 ml of water-containing ethanol (90 wt% of ethanol) at 40 to 50 ° C. for filtration, and the residue was digested again in the same manner several times to obtain 1.5 l of the extract. Obtained. 100 ml of purified water was added to the residue obtained by concentration under reduced pressure, the mixture was aged for 1 week, the insoluble portion was filtered off, and the obtained extract was concentrated under reduced pressure. Then, ethanol was added to the extract to obtain an ethanol content of 4 wt.
% To obtain 1000 ml of Aspergillus flavus (100 g of this extract was concentrated under reduced pressure and then extracted with 200 ml of ethyl acetate (40 ml × 5 times), and then ethyl acetate was extracted from this extract. The residue distilled off under reduced pressure was 0.95 to 1.05 g).

The hair nourishing cosmetic composition of the present invention can be made into a dosage form such as a hairnic, a hair lotion, a hair cream, a hair conditioner, a shampoo, a rinse, a hair gel, a hair mist and a hair foam according to a conventional method. is there. Further, the hair nourishing cosmetic of the present invention may be appropriately blended with a dye, a fragrance, a bactericide, an antiseptic, a keratolytic agent, an antiandrogen, an antioxidant, etc. within a range that achieves the object of the present invention. it can.

The present invention will be described in detail below based on Examples and Comparative Examples.

The mouse hair growth promoting effect test method, human hair hair growth promoting effect test method and practical test method described in Examples are shown below.

(1) Test method for mouse hair growth promoting effect C3H mice (male, 8 weeks old, average weight 35 g) were shaved at the center of the back with electric clippers and then completely shaved by a shaver. From the next day, 0.2 ml per animal of each sample of Example and Comparative Example was applied once daily to the skin of the test site. For each sample, 10 animals were used per group. still,
The base alone was applied as a control group. On the 15th day after the start of the experiment, the animals were sacrificed and the skin of the test area was photographed. Next, the photograph was taken into the image analysis device, the area (A) where the hair was first shaved and the hair-growth area (B) were obtained, and the hair-growth rate (%) = (B) / (A) × 100 was individually calculated. Was calculated for each animal. Finally, a value obtained by dividing the average value of each group of Examples or Comparative Examples by the average value of the control group was used as the hair growth promoting effect for determination.

(2) Human hair growth promoting effect test method Male subject 1 in the thirties and forties with a decline in hair growth 1
The hair of the 0 head of the head was shaved into a circular shape having a diameter of about 7 mm.
Furthermore, the method of Hayashi et al. (British Journal of Dermatology, 125
Vol. 123, 1991), the hair growth rate was determined for the hair (about 30-40 hairs) at the target site, and the average value was calculated (A). Next, each subject was applied with about 3 ml of the sample of the Example or Comparative Example twice daily in the morning and evening, focusing on the test site, and massaged well. The hair growth rate at the same site was measured in the same manner 3 months after the start of the test, and the average value (B) was calculated. The effect was determined by comparing the ratio (B) / (A) before and after the use of each hair nourishing cosmetic.

(3) Practical test method Male subject 2 in the thirties and forties with a decline in hair growth 2
The effect was evaluated after applying the sample to the heads of 0 people twice a day every morning and evening for 5 consecutive months. The test results responded that "hairy hair became bristle or increased hair loss", "less hair loss", "less dandruff" for each item of hair growth effect and hair loss prevention effect The number of people

Examples 1 to 6 and Comparative Examples 1 to 5 [Heartonic] In the raw material composition of Table 1 below, Table 2
Γ-amino-humanroxybutyric acid (hereinafter referred to as G
Abbreviated as ABOB), GABOB sodium salt (GA
BOB-Na), GABOB potassium salt (GABOB-
K), assembly extract, and dihydric alcohol, propylene glycol (PG), 1,3-butylene glycol (BG), and polyethylene glycol (PEG) having a molecular weight of 300 are blended in predetermined amounts to prepare respective hairnics, The above tests were carried out.

[0015]

[Table 1]

(2) Preparation method Components (C), (D), and (E) are uniformly mixed and dissolved in the component (B), and the component (A) is uniformly mixed and dispersed in this solution with stirring. Fill the container. When using these hair tonics, the contents are uniformly dispersed by shaking.

(3) Characteristics Table 2 below shows the results of various tests carried out by each Heartonic. In comparison with the hair artics of Comparative Examples 1 to 5 in which GABOB and at least one of its salts, assembly extract and dihydric alcohol are not used in combination, the hair artics of Examples 1 to 6 of the present invention are clear in various tests. A good effect was recognized.

[0018]

[Table 2]

[0019]

EFFECTS OF THE INVENTION As described above, it is apparent that the present invention provides a useful hair nourishing cosmetic composition which is excellent in hair growth effect, hair nourishing effect, hair loss prevention, dandruff prevention and the like.

Claims (1)

[Claims] 1. A hair nourishing cosmetic composition containing at least one of γ-amino-β-hydroxybutyric acid and a salt thereof, an assembly extract, and at least one of a dihydric alcohol.