JPH0667973B2 - イオノゲン基又は反応基を持つ両親媒性化合物を表面に植込んで含有する重合体粒子又はこの粒子よりなるラテックスの製造方法 - Google Patents
イオノゲン基又は反応基を持つ両親媒性化合物を表面に植込んで含有する重合体粒子又はこの粒子よりなるラテックスの製造方法Info
- Publication number
- JPH0667973B2 JPH0667973B2 JP63112682A JP11268288A JPH0667973B2 JP H0667973 B2 JPH0667973 B2 JP H0667973B2 JP 63112682 A JP63112682 A JP 63112682A JP 11268288 A JP11268288 A JP 11268288A JP H0667973 B2 JPH0667973 B2 JP H0667973B2
- Authority
- JP
- Japan
- Prior art keywords
- particles
- polymerization initiator
- seed
- aqueous dispersion
- monomer composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 title claims abstract description 55
- 150000001875 compounds Chemical class 0.000 title claims abstract description 39
- 229920000642 polymer Polymers 0.000 title claims abstract description 29
- 238000004519 manufacturing process Methods 0.000 title claims description 3
- 239000004816 latex Substances 0.000 title description 14
- 229920000126 latex Polymers 0.000 title description 14
- 239000000178 monomer Substances 0.000 claims abstract description 29
- 239000006185 dispersion Substances 0.000 claims abstract description 24
- 238000000034 method Methods 0.000 claims abstract description 15
- 238000000354 decomposition reaction Methods 0.000 claims abstract description 10
- 230000008961 swelling Effects 0.000 claims abstract description 3
- 239000000203 mixture Substances 0.000 claims description 21
- 239000003505 polymerization initiator Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 239000003995 emulsifying agent Substances 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 5
- 125000005702 oxyalkylene group Chemical group 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical group C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 claims description 3
- 125000000217 alkyl group Chemical group 0.000 claims description 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 3
- SRSFOMHQIATOFV-UHFFFAOYSA-N octanoyl octaneperoxoate Chemical group CCCCCCCC(=O)OOC(=O)CCCCCCC SRSFOMHQIATOFV-UHFFFAOYSA-N 0.000 claims description 3
- OEPOKWHJYJXUGD-UHFFFAOYSA-N 2-(3-phenylmethoxyphenyl)-1,3-thiazole-4-carbaldehyde Chemical compound O=CC1=CSC(C=2C=C(OCC=3C=CC=CC=3)C=CC=2)=N1 OEPOKWHJYJXUGD-UHFFFAOYSA-N 0.000 claims description 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims description 2
- 239000005977 Ethylene Substances 0.000 claims description 2
- BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 claims description 2
- 125000005907 alkyl ester group Chemical group 0.000 claims description 2
- XJOBOFWTZOKMOH-UHFFFAOYSA-N decanoyl decaneperoxoate Chemical compound CCCCCCCCCC(=O)OOC(=O)CCCCCCCCC XJOBOFWTZOKMOH-UHFFFAOYSA-N 0.000 claims description 2
- MYHUVPFQXXOTBI-UHFFFAOYSA-N decoxycarbonyloxy decyl carbonate Chemical compound CCCCCCCCCCOC(=O)OOC(=O)OCCCCCCCCCC MYHUVPFQXXOTBI-UHFFFAOYSA-N 0.000 claims description 2
- 150000001993 dienes Chemical class 0.000 claims description 2
- DHRQKFYLKJURNK-UHFFFAOYSA-N dodecoxycarbonyloxy dodecyl carbonate Chemical compound CCCCCCCCCCCCOC(=O)OOC(=O)OCCCCCCCCCCCC DHRQKFYLKJURNK-UHFFFAOYSA-N 0.000 claims description 2
- 230000009477 glass transition Effects 0.000 claims description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical group OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 1
- 239000004952 Polyamide Substances 0.000 claims 1
- 125000003262 carboxylic acid ester group Chemical class [H]C([H])([*:2])OC(=O)C([H])([H])[*:1] 0.000 claims 1
- 150000002433 hydrophilic molecules Chemical class 0.000 claims 1
- 150000002825 nitriles Chemical group 0.000 claims 1
- ZTFMJDHQENZIHJ-UHFFFAOYSA-N octanoyloxycarbonylperoxycarbonyl octanoate Chemical compound CCCCCCCC(=O)OC(=O)OOC(=O)OC(=O)CCCCCCC ZTFMJDHQENZIHJ-UHFFFAOYSA-N 0.000 claims 1
- 229920002647 polyamide Polymers 0.000 claims 1
- 229920002721 polycyanoacrylate Polymers 0.000 claims 1
- 230000000379 polymerizing effect Effects 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
- 239000003999 initiator Substances 0.000 abstract description 7
- 238000009792 diffusion process Methods 0.000 abstract description 4
- 239000000470 constituent Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 16
- -1 etc.) Chemical compound 0.000 description 10
- 239000004793 Polystyrene Substances 0.000 description 8
- 238000002513 implantation Methods 0.000 description 7
- 229920002223 polystyrene Polymers 0.000 description 7
- 150000002148 esters Chemical class 0.000 description 6
- BDJRBEYXGGNYIS-UHFFFAOYSA-N nonanedioic acid Chemical compound OC(=O)CCCCCCCC(O)=O BDJRBEYXGGNYIS-UHFFFAOYSA-N 0.000 description 6
- 239000000284 extract Substances 0.000 description 5
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 description 5
- 125000000524 functional group Chemical group 0.000 description 4
- 239000012762 magnetic filler Substances 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 3
- 125000004432 carbon atom Chemical group C* 0.000 description 3
- 230000002209 hydrophobic effect Effects 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 238000006116 polymerization reaction Methods 0.000 description 3
- 238000000108 ultra-filtration Methods 0.000 description 3
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 2
- KAKZBPTYRLMSJV-UHFFFAOYSA-N Butadiene Chemical compound C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 description 2
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 2
- 150000001408 amides Chemical class 0.000 description 2
- QVQLCTNNEUAWMS-UHFFFAOYSA-N barium oxide Chemical compound [Ba]=O QVQLCTNNEUAWMS-UHFFFAOYSA-N 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- AMWRITDGCCNYAT-UHFFFAOYSA-L hydroxy(oxo)manganese;manganese Chemical compound [Mn].O[Mn]=O.O[Mn]=O AMWRITDGCCNYAT-UHFFFAOYSA-L 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- DUIOPKIIICUYRZ-UHFFFAOYSA-N semicarbazide group Chemical group NNC(=O)N DUIOPKIIICUYRZ-UHFFFAOYSA-N 0.000 description 2
- 150000003573 thiols Chemical group 0.000 description 2
- NWZSZGALRFJKBT-KNIFDHDWSA-N (2s)-2,6-diaminohexanoic acid;(2s)-2-hydroxybutanedioic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O.NCCCC[C@H](N)C(O)=O NWZSZGALRFJKBT-KNIFDHDWSA-N 0.000 description 1
- XVMSFILGAMDHEY-UHFFFAOYSA-N 6-(4-aminophenyl)sulfonylpyridin-3-amine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)C1=CC=C(N)C=N1 XVMSFILGAMDHEY-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- UQBOJOOOTLPNST-UHFFFAOYSA-N Dehydroalanine Chemical group NC(=C)C(O)=O UQBOJOOOTLPNST-UHFFFAOYSA-N 0.000 description 1
- QOSSAOTZNIDXMA-UHFFFAOYSA-N Dicylcohexylcarbodiimide Chemical compound C1CCCCC1N=C=NC1CCCCC1 QOSSAOTZNIDXMA-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 description 1
- 229910000519 Ferrosilicon Inorganic materials 0.000 description 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
- 229920007962 Styrene Methyl Methacrylate Polymers 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004520 agglutination Effects 0.000 description 1
- 125000003158 alcohol group Chemical group 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 229910001566 austenite Inorganic materials 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 150000001718 carbodiimides Chemical class 0.000 description 1
- 150000001733 carboxylic acid esters Chemical class 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 229940090961 chromium dioxide Drugs 0.000 description 1
- AYTAKQFHWFYBMA-UHFFFAOYSA-N chromium(IV) oxide Inorganic materials O=[Cr]=O AYTAKQFHWFYBMA-UHFFFAOYSA-N 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 229910000428 cobalt oxide Inorganic materials 0.000 description 1
- IVMYJDGYRUAWML-UHFFFAOYSA-N cobalt(ii) oxide Chemical compound [Co]=O IVMYJDGYRUAWML-UHFFFAOYSA-N 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 239000007822 coupling agent Substances 0.000 description 1
- ATDGTVJJHBUTRL-UHFFFAOYSA-N cyanogen bromide Chemical compound BrC#N ATDGTVJJHBUTRL-UHFFFAOYSA-N 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000006193 diazotization reaction Methods 0.000 description 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 230000032050 esterification Effects 0.000 description 1
- 238000005886 esterification reaction Methods 0.000 description 1
- SUPCQIBBMFXVTL-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate Chemical compound CCOC(=O)C(C)=C SUPCQIBBMFXVTL-UHFFFAOYSA-N 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 238000007306 functionalization reaction Methods 0.000 description 1
- IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 239000003317 industrial substance Substances 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 230000002262 irrigation Effects 0.000 description 1
- 238000003973 irrigation Methods 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- ADFPJHOAARPYLP-UHFFFAOYSA-N methyl 2-methylprop-2-enoate;styrene Chemical compound COC(=O)C(C)=C.C=CC1=CC=CC=C1 ADFPJHOAARPYLP-UHFFFAOYSA-N 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 239000011733 molybdenum Substances 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 125000002560 nitrile group Chemical group 0.000 description 1
- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- AMEVLYGGLRIBIO-UHFFFAOYSA-N octoxycarbonyloxy octyl carbonate Chemical compound CCCCCCCCOC(=O)OOC(=O)OCCCCCCCC AMEVLYGGLRIBIO-UHFFFAOYSA-N 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 125000000962 organic group Chemical group 0.000 description 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- HJWLCRVIBGQPNF-UHFFFAOYSA-N prop-2-enylbenzene Chemical compound C=CCC1=CC=CC=C1 HJWLCRVIBGQPNF-UHFFFAOYSA-N 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 229910001404 rare earth metal oxide Inorganic materials 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- DVKJHBMWWAPEIU-UHFFFAOYSA-N toluene 2,4-diisocyanate Chemical compound CC1=CC=C(N=C=O)C=C1N=C=O DVKJHBMWWAPEIU-UHFFFAOYSA-N 0.000 description 1
- 229910052720 vanadium Inorganic materials 0.000 description 1
- GPPXJZIENCGNKB-UHFFFAOYSA-N vanadium Chemical compound [V]#[V] GPPXJZIENCGNKB-UHFFFAOYSA-N 0.000 description 1
- 239000003039 volatile agent Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Dispersion Chemistry (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Polymerisation Methods In General (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Graft Or Block Polymers (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Materials For Medical Uses (AREA)
- Peptides Or Proteins (AREA)
- Polyethers (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8706550A FR2615192B1 (fr) | 1987-05-11 | 1987-05-11 | Procede de preparation de particules de polymere ou de latex constitues de particules de polymere comportant, implantees a leur surface, des molecules amphiphiles portant des groupes ionogenes ou reactifs |
| FR87/06550 | 1987-05-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6465102A JPS6465102A (en) | 1989-03-10 |
| JPH0667973B2 true JPH0667973B2 (ja) | 1994-08-31 |
Family
ID=9350946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63112682A Expired - Lifetime JPH0667973B2 (ja) | 1987-05-11 | 1988-05-11 | イオノゲン基又は反応基を持つ両親媒性化合物を表面に植込んで含有する重合体粒子又はこの粒子よりなるラテックスの製造方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4929662A (enExample) |
| EP (1) | EP0291390B1 (enExample) |
| JP (1) | JPH0667973B2 (enExample) |
| KR (1) | KR910009291B1 (enExample) |
| CN (1) | CN1031539A (enExample) |
| AT (1) | ATE72049T1 (enExample) |
| AU (1) | AU605292B2 (enExample) |
| BR (1) | BR8802279A (enExample) |
| DE (1) | DE3867900D1 (enExample) |
| DK (1) | DK256188A (enExample) |
| ES (1) | ES2028321T3 (enExample) |
| FR (1) | FR2615192B1 (enExample) |
| GR (1) | GR3003741T3 (enExample) |
| IL (1) | IL86323A (enExample) |
| PT (1) | PT87448B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5166000A (en) * | 1991-10-10 | 1992-11-24 | Nanofilm Corporation | Method of applying thin films of amphiphilic molecules to substrates |
| FR2735778B1 (fr) * | 1995-06-22 | 1997-08-22 | Prolabo Sa | Nouveau latex de microspheres magnetisables monodisperses calibrees, procede de preparation et utilisation dudit latex en chimie ou en biologie |
| US5981296A (en) * | 1997-02-18 | 1999-11-09 | Dade Behring Inc. | Stabilization of particle reagents |
| EP3190417A4 (en) * | 2014-09-02 | 2018-04-18 | LSI Medience Corporation | Polymer microparticle for carrying physiologically active substance and method for preparing same |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2461920A (en) * | 1944-01-25 | 1949-02-15 | Du Pont | Polyhydric alcohol mixed esters |
| FR1537741A (fr) * | 1967-06-09 | 1968-08-30 | Wolfen Filmfab Veb | Procédé de préparation de résines vinyliques échangeuses d'ions |
| JPS5443572B2 (enExample) * | 1974-07-08 | 1979-12-20 | ||
| US4157323A (en) * | 1976-06-09 | 1979-06-05 | California Institute Of Technology | Metal containing polymeric functional microspheres |
| US4217344A (en) * | 1976-06-23 | 1980-08-12 | L'oreal | Compositions containing aqueous dispersions of lipid spheres |
| FR2450263A1 (fr) * | 1979-02-28 | 1980-09-26 | Dow Chemical Co | Procede pour coupler une proteine sur un latex portant des groupes epoxyde et produits obtenus par ce procede |
| FR2480764B1 (fr) * | 1980-04-18 | 1985-10-04 | Rhone Poulenc Spec Chim | Latex de polymeres magnetiques et procede de preparation |
| US4333969A (en) * | 1980-12-23 | 1982-06-08 | Atlantic Richfield Company | Process for producing styrenic polymer beads of preferred bead size |
| FI842992A0 (fi) * | 1984-07-26 | 1984-07-26 | Labsystems Oy | Immunologiskt definitionsfoerfarande. |
| DE3523319A1 (de) * | 1985-06-29 | 1987-01-08 | Basf Ag | Bindemittel fuer waessrige, physikalisch trocknende korrosionsschutzanstriche auf basis einer phosphorsaeuremonoalkylester enthaltenden polymer-dispersion |
| US4855127A (en) * | 1986-07-07 | 1989-08-08 | Dow Corning Corporation | Lattice-entrapped composition |
-
1987
- 1987-05-11 FR FR8706550A patent/FR2615192B1/fr not_active Expired
-
1988
- 1988-05-04 AT AT88401079T patent/ATE72049T1/de not_active IP Right Cessation
- 1988-05-04 ES ES198888401079T patent/ES2028321T3/es not_active Expired - Lifetime
- 1988-05-04 DE DE8888401079T patent/DE3867900D1/de not_active Expired - Lifetime
- 1988-05-04 EP EP88401079A patent/EP0291390B1/fr not_active Expired - Lifetime
- 1988-05-06 US US07/191,176 patent/US4929662A/en not_active Expired - Lifetime
- 1988-05-09 AU AU15833/88A patent/AU605292B2/en not_active Ceased
- 1988-05-09 IL IL86323A patent/IL86323A/xx unknown
- 1988-05-10 BR BR8802279A patent/BR8802279A/pt unknown
- 1988-05-10 PT PT87448A patent/PT87448B/pt not_active IP Right Cessation
- 1988-05-10 DK DK256188A patent/DK256188A/da not_active Application Discontinuation
- 1988-05-10 CN CN88102645A patent/CN1031539A/zh active Pending
- 1988-05-11 KR KR1019880005485A patent/KR910009291B1/ko not_active Expired
- 1988-05-11 JP JP63112682A patent/JPH0667973B2/ja not_active Expired - Lifetime
-
1992
- 1992-02-07 GR GR920400164T patent/GR3003741T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL86323A (en) | 1991-12-15 |
| EP0291390A1 (fr) | 1988-11-17 |
| PT87448A (pt) | 1989-05-31 |
| PT87448B (pt) | 1992-08-31 |
| DK256188A (da) | 1989-01-19 |
| FR2615192B1 (fr) | 1989-12-01 |
| CN1031539A (zh) | 1989-03-08 |
| FR2615192A1 (fr) | 1988-11-18 |
| BR8802279A (pt) | 1988-12-13 |
| JPS6465102A (en) | 1989-03-10 |
| AU1583388A (en) | 1988-11-17 |
| IL86323A0 (en) | 1988-11-15 |
| AU605292B2 (en) | 1991-01-10 |
| KR910009291B1 (ko) | 1991-11-09 |
| ES2028321T3 (es) | 1992-07-01 |
| ATE72049T1 (de) | 1992-02-15 |
| GR3003741T3 (enExample) | 1993-03-16 |
| KR880014014A (ko) | 1988-12-22 |
| EP0291390B1 (fr) | 1992-01-22 |
| US4929662A (en) | 1990-05-29 |
| DE3867900D1 (de) | 1992-03-05 |
| DK256188D0 (da) | 1988-05-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0065069B1 (de) | Latex zur Immobilisierung von biologisch wirksamen Substanzen | |
| JPH02286729A (ja) | 疎水性架橋ポリマーの磁化可能複合微小球、その製造方法およびその生物学における応用 | |
| US6573313B2 (en) | Amphiphilic core-shell latexes | |
| DK175890B1 (da) | Fremgangsmåde til fremstilling af bionedbrydelige mikrokugler | |
| JPH0667972B2 (ja) | イオノゲン基又は反応基を持つ両親媒性分子を表面に植込んで含有する重合体粒子、その製造方法及び生物学への使用 | |
| AU667003B2 (en) | Vaccine preparations | |
| MXPA04011846A (es) | Metodos para hacer polimeros biodegradables funcionales. | |
| WO1987006007A1 (en) | Immobilized physiologically active material | |
| JPH1072427A (ja) | Ｎ，ｏ−ジメタクリロイルヒドロキシルアミン | |
| EP0129719A2 (de) | Makroporöse Perlpolymerisate, Verfahren zu ihrer Herstellung und ihre Anwendung | |
| WO1997024382A1 (en) | Foldable intraocular lens materials | |
| KR19990037951A (ko) | 폴리(2-하이드록시에틸(메타)아크릴레이트)세그멘트를분자중에함유하고있는개질폴리머 | |
| JPH0667973B2 (ja) | イオノゲン基又は反応基を持つ両親媒性化合物を表面に植込んで含有する重合体粒子又はこの粒子よりなるラテックスの製造方法 | |
| JP3215455B2 (ja) | ポリオキシアルキレン側鎖含有共重合体 | |
| EP1125590A2 (en) | Bioadhesive composition | |
| GB2240547A (en) | New compositions | |
| JP2010065067A (ja) | 粒子およびその製造方法、ならびにゲル | |
| Kálal | Interaction of synthetic polymers with components of the living materials | |
| WO1996034626A1 (en) | Composition of tyrosine and polymerised allergen | |
| JP2683715B2 (ja) | カチオン高分子電解質共重合体ラテックス | |
| JPH10234846A (ja) | 抗血栓性材料 | |
| Gökay et al. | Synthesis of diagnostic test kits for syphilis with polymeric particles | |
| JPS63112603A (ja) | 活性化粒子担体 | |
| JPS61199864A (ja) | エンドトキシンの固定化方法 | |
| JPS58116683A (ja) | 固定化菌体又は固定化酵素及びその製造法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20080831 Year of fee payment: 14 |
|
| EXPY | Cancellation because of completion of term | ||
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20080831 Year of fee payment: 14 |