JPH0660131B2 - ｇｅｍ−ジハロ及びテトラハロ−１，１２−ジアミノ−４，９−ジアザドデカン類 - Google Patents
ｇｅｍ−ジハロ及びテトラハロ−１，１２−ジアミノ−４，９−ジアザドデカン類Info
- Publication number
- JPH0660131B2 JPH0660131B2 JP61192211A JP19221186A JPH0660131B2 JP H0660131 B2 JPH0660131 B2 JP H0660131B2 JP 61192211 A JP61192211 A JP 61192211A JP 19221186 A JP19221186 A JP 19221186A JP H0660131 B2 JPH0660131 B2 JP H0660131B2
- Authority
- JP
- Japan
- Prior art keywords
- dihalo
- diazadodecane
- toluenesulfonyl
- diamino
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76793485A | 1985-08-21 | 1985-08-21 | |
| US767934 | 1985-08-21 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6035234A Division JPH0798777B2 (ja) | 1985-08-21 | 1994-02-09 | ２，２−ジハロ−１，４−ジアミノブタン化合物及び製薬上受入れられるその塩 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6245565A JPS6245565A (ja) | 1987-02-27 |
| JPH0660131B2 true JPH0660131B2 (ja) | 1994-08-10 |
Family
ID=25081013
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61192211A Expired - Lifetime JPH0660131B2 (ja) | 1985-08-21 | 1986-08-19 | ｇｅｍ−ジハロ及びテトラハロ−１，１２−ジアミノ−４，９−ジアザドデカン類 |
| JP6035234A Expired - Lifetime JPH0798777B2 (ja) | 1985-08-21 | 1994-02-09 | ２，２−ジハロ−１，４−ジアミノブタン化合物及び製薬上受入れられるその塩 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6035234A Expired - Lifetime JPH0798777B2 (ja) | 1985-08-21 | 1994-02-09 | ２，２−ジハロ−１，４−ジアミノブタン化合物及び製薬上受入れられるその塩 |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0220409B1 (da) |
| JP (2) | JPH0660131B2 (da) |
| KR (1) | KR900006124B1 (da) |
| CN (1) | CN1012815B (da) |
| AR (1) | AR242554A1 (da) |
| AT (1) | ATE69801T1 (da) |
| AU (1) | AU585052B2 (da) |
| CA (1) | CA1274547A (da) |
| DE (1) | DE3682652D1 (da) |
| DK (1) | DK396786A (da) |
| ES (1) | ES2001247A6 (da) |
| FI (1) | FI84817C (da) |
| GR (1) | GR862148B (da) |
| HU (1) | HUT44754A (da) |
| IL (1) | IL79753A0 (da) |
| NO (1) | NO164973C (da) |
| NZ (1) | NZ217247A (da) |
| PT (1) | PT83232B (da) |
| ZA (1) | ZA866180B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4695654A (en) * | 1985-08-21 | 1987-09-22 | Merrell Dow Pharmaceuticals Inc. | Gem-dihalo-1,8-diamino-4-aza-octanes |
| JPH06181890A (ja) * | 1992-10-06 | 1994-07-05 | Terumo Corp | Ｍｒｉ造影剤 |
| KR101286158B1 (ko) * | 2011-08-24 | 2013-07-15 | 씨제이제일제당 (주) | 발효액에서 1,4-디아미노부탄의 분리 및 정제하는 방법 |
| CN109456198A (zh) * | 2018-11-14 | 2019-03-12 | 上海阿拉丁生化科技股份有限公司 | 一种2,2`-二氨基-n-甲基二乙胺的合成方法 |
| CN116162029A (zh) * | 2022-12-12 | 2023-05-26 | 苏州永健生物医药有限公司 | 一种精胺的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4004996A (en) * | 1974-12-23 | 1977-01-25 | Merck & Co., Inc. | Fluorination of organic compounds |
| GB2082579B (en) * | 1980-08-23 | 1984-02-08 | Merrell Toraude & Co | Fluorinated diaminobutane derivatives |
| US4695654A (en) * | 1985-08-21 | 1987-09-22 | Merrell Dow Pharmaceuticals Inc. | Gem-dihalo-1,8-diamino-4-aza-octanes |
-
1986
- 1986-08-15 CA CA000615543A patent/CA1274547A/en not_active Expired - Lifetime
- 1986-08-15 ZA ZA866180A patent/ZA866180B/xx unknown
- 1986-08-18 AU AU61557/86A patent/AU585052B2/en not_active Ceased
- 1986-08-18 NZ NZ217247A patent/NZ217247A/xx unknown
- 1986-08-18 IL IL79753A patent/IL79753A0/xx not_active IP Right Cessation
- 1986-08-18 HU HU863620A patent/HUT44754A/hu unknown
- 1986-08-18 GR GR862148A patent/GR862148B/el unknown
- 1986-08-19 AR AR86304959A patent/AR242554A1/es active
- 1986-08-19 JP JP61192211A patent/JPH0660131B2/ja not_active Expired - Lifetime
- 1986-08-19 FI FI863353A patent/FI84817C/fi not_active IP Right Cessation
- 1986-08-20 PT PT83232A patent/PT83232B/pt not_active IP Right Cessation
- 1986-08-20 AT AT86111504T patent/ATE69801T1/de not_active IP Right Cessation
- 1986-08-20 EP EP86111504A patent/EP0220409B1/en not_active Expired - Lifetime
- 1986-08-20 CN CN86105088A patent/CN1012815B/zh not_active Expired
- 1986-08-20 NO NO863344A patent/NO164973C/no unknown
- 1986-08-20 DK DK396786A patent/DK396786A/da not_active Application Discontinuation
- 1986-08-20 ES ES8601228A patent/ES2001247A6/es not_active Expired
- 1986-08-20 DE DE8686111504T patent/DE3682652D1/de not_active Expired - Fee Related
- 1986-08-21 KR KR1019860006896A patent/KR900006124B1/ko not_active IP Right Cessation
-
1994
- 1994-02-09 JP JP6035234A patent/JPH0798777B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK396786D0 (da) | 1986-08-20 |
| DK396786A (da) | 1987-02-22 |
| CN86105088A (zh) | 1987-04-29 |
| FI863353A0 (fi) | 1986-08-19 |
| EP0220409A2 (en) | 1987-05-06 |
| ZA866180B (en) | 1987-04-29 |
| ATE69801T1 (de) | 1991-12-15 |
| EP0220409B1 (en) | 1991-11-27 |
| GR862148B (en) | 1986-12-23 |
| IL79753A0 (en) | 1986-11-30 |
| FI84817B (fi) | 1991-10-15 |
| PT83232B (pt) | 1988-07-01 |
| JPS6245565A (ja) | 1987-02-27 |
| AU585052B2 (en) | 1989-06-08 |
| NO863344D0 (no) | 1986-08-20 |
| CA1274547C (en) | 1990-09-25 |
| EP0220409A3 (en) | 1988-12-14 |
| DE3682652D1 (de) | 1992-01-09 |
| NO863344L (no) | 1987-02-23 |
| CN1012815B (zh) | 1991-06-12 |
| CA1274547A (en) | 1990-09-25 |
| HUT44754A (en) | 1988-04-28 |
| JPH0798777B2 (ja) | 1995-10-25 |
| FI84817C (fi) | 1992-01-27 |
| NZ217247A (en) | 1989-10-27 |
| PT83232A (en) | 1986-09-01 |
| FI863353A (fi) | 1987-02-22 |
| JPH072741A (ja) | 1995-01-06 |
| AR242554A1 (es) | 1993-04-30 |
| NO164973B (no) | 1990-08-27 |
| ES2001247A6 (es) | 1988-05-01 |
| NO164973C (no) | 1990-12-05 |
| KR900006124B1 (ko) | 1990-08-24 |
| AU6155786A (en) | 1987-02-26 |
| KR870002046A (ko) | 1987-03-28 |
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