JPH0656841A - オキサビシクロヘプチル置換オキサゾールアミド類の製造法 - Google Patents

オキサビシクロヘプチル置換オキサゾールアミド類の製造法

Info

Publication number
JPH0656841A
JPH0656841A JP5147351A JP14735193A JPH0656841A JP H0656841 A JPH0656841 A JP H0656841A JP 5147351 A JP5147351 A JP 5147351A JP 14735193 A JP14735193 A JP 14735193A JP H0656841 A JPH0656841 A JP H0656841A
Authority
JP
Japan
Prior art keywords
oxazoline
dbu
amine
formula
hydride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP5147351A
Other languages
English (en)
Japanese (ja)
Inventor
Richard H Mueller
リチャード・エイチ・ミューラー
Janak Singh
ジャナック・シン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
ER Squibb and Sons LLC
Original Assignee
Bristol Myers Squibb Co
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co, ER Squibb and Sons LLC filed Critical Bristol Myers Squibb Co
Publication of JPH0656841A publication Critical patent/JPH0656841A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP5147351A 1992-06-18 1993-06-18 オキサビシクロヘプチル置換オキサゾールアミド類の製造法 Withdrawn JPH0656841A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US900384 1978-04-26
US90038492A 1992-06-18 1992-06-18

Publications (1)

Publication Number Publication Date
JPH0656841A true JPH0656841A (ja) 1994-03-01

Family

ID=25412426

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5147351A Withdrawn JPH0656841A (ja) 1992-06-18 1993-06-18 オキサビシクロヘプチル置換オキサゾールアミド類の製造法

Country Status (11)

Country Link
US (1) US5281716A (enExample)
EP (1) EP0575069A1 (enExample)
JP (1) JPH0656841A (enExample)
KR (1) KR940000463A (enExample)
CN (1) CN1082043A (enExample)
CA (1) CA2096667A1 (enExample)
FI (1) FI932770A7 (enExample)
HU (1) HUT68401A (enExample)
IL (1) IL105779A0 (enExample)
MX (1) MX9303573A (enExample)
TW (1) TW232692B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101633747B1 (ko) * 2015-08-10 2016-06-27 현대위아 주식회사 별치형 공구교환 장치

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5539126A (en) * 1994-04-20 1996-07-23 Bristol-Myers Squibb Company Method for preparing homochiral maleimide intermediates, via silylation techniques
US6407250B1 (en) * 2000-09-14 2002-06-18 Allergan Sales, Inc. Interphenylene 7-oxabicyclic [2.2.1] heptane oxazoles as prostaglandin F2a antagonists
AU2018375378A1 (en) * 2017-11-29 2020-05-28 Vanderbilt University Methods of inhibiting tumor metastasis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100889A (en) * 1989-04-03 1992-03-31 E. R. Squibb & Sons, Inc. 7-oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease
NZ232897A (en) * 1989-04-03 1992-12-23 Squibb & Sons Inc Interphenylene 7-oxabicycloheptyl substituted heterocyclic amide prostaglandin analogues, preparation and pharmaceutical compositions thereof
US5290799A (en) * 1990-09-19 1994-03-01 E. R. Squibb & Sons, Inc. 7-oxabicycloheptyl substituted heterocyclic thioamide prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101633747B1 (ko) * 2015-08-10 2016-06-27 현대위아 주식회사 별치형 공구교환 장치

Also Published As

Publication number Publication date
FI932770A7 (fi) 1993-12-19
EP0575069A1 (fr) 1993-12-22
TW232692B (enExample) 1994-10-21
HUT68401A (en) 1995-06-28
US5281716A (en) 1994-01-25
IL105779A0 (en) 1993-09-22
MX9303573A (es) 1994-01-31
HU9301796D0 (en) 1993-09-28
FI932770A0 (fi) 1993-06-16
KR940000463A (ko) 1994-01-03
CN1082043A (zh) 1994-02-16
CA2096667A1 (en) 1993-12-19

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Legal Events

Date Code Title Description
A300 Application deemed to be withdrawn because no request for examination was validly filed

Free format text: JAPANESE INTERMEDIATE CODE: A300

Effective date: 20000905