JPH06506206A - コラゲナーゼ阻害剤としてのチオールカルボン酸誘導体 - Google Patents
コラゲナーゼ阻害剤としてのチオールカルボン酸誘導体Info
- Publication number
- JPH06506206A JPH06506206A JP4507179A JP50717992A JPH06506206A JP H06506206 A JPH06506206 A JP H06506206A JP 4507179 A JP4507179 A JP 4507179A JP 50717992 A JP50717992 A JP 50717992A JP H06506206 A JPH06506206 A JP H06506206A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- hydrogen
- compound
- alkyl
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9107367.6 | 1991-04-08 | ||
GB919107367A GB9107367D0 (en) | 1991-04-08 | 1991-04-08 | Novel compounds |
PCT/GB1992/000612 WO1992017444A1 (fr) | 1991-04-08 | 1992-04-06 | Derives d'acide thiol-carboxylique a titre d'inhibiteurs de collagenase |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH06506206A true JPH06506206A (ja) | 1994-07-14 |
Family
ID=10692842
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4507179A Pending JPH06506206A (ja) | 1991-04-08 | 1992-04-06 | コラゲナーゼ阻害剤としてのチオールカルボン酸誘導体 |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0579648A1 (fr) |
JP (1) | JPH06506206A (fr) |
AU (1) | AU1456792A (fr) |
CA (1) | CA2107334A1 (fr) |
GB (1) | GB9107367D0 (fr) |
IE (1) | IE921100A1 (fr) |
MX (1) | MX9201575A (fr) |
NZ (1) | NZ242240A (fr) |
PT (1) | PT100353A (fr) |
TW (1) | TW210333B (fr) |
WO (1) | WO1992017444A1 (fr) |
ZA (1) | ZA922501B (fr) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4937243A (en) * | 1986-12-24 | 1990-06-26 | Beecham Group P.L.C. | Thiol carboxylic acid derivatives and their use as colagenase inhibitors |
GB8729804D0 (en) * | 1987-12-22 | 1988-02-03 | Beecham Group Plc | Novel compounds |
-
1991
- 1991-04-08 GB GB919107367A patent/GB9107367D0/en active Pending
-
1992
- 1992-04-06 CA CA002107334A patent/CA2107334A1/fr not_active Abandoned
- 1992-04-06 NZ NZ242240A patent/NZ242240A/xx unknown
- 1992-04-06 EP EP92907683A patent/EP0579648A1/fr not_active Ceased
- 1992-04-06 WO PCT/GB1992/000612 patent/WO1992017444A1/fr not_active Application Discontinuation
- 1992-04-06 AU AU14567/92A patent/AU1456792A/en not_active Abandoned
- 1992-04-06 MX MX9201575A patent/MX9201575A/es unknown
- 1992-04-06 JP JP4507179A patent/JPH06506206A/ja active Pending
- 1992-04-07 IE IE110092A patent/IE921100A1/en unknown
- 1992-04-07 TW TW081102615A patent/TW210333B/zh active
- 1992-04-07 ZA ZA922501A patent/ZA922501B/xx unknown
- 1992-04-07 PT PT100353A patent/PT100353A/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
GB9107367D0 (en) | 1991-05-22 |
IE921100A1 (en) | 1992-10-21 |
MX9201575A (es) | 1993-08-01 |
ZA922501B (en) | 1993-10-07 |
AU1456792A (en) | 1992-11-02 |
PT100353A (pt) | 1993-06-30 |
CA2107334A1 (fr) | 1992-10-09 |
WO1992017444A1 (fr) | 1992-10-15 |
NZ242240A (en) | 1993-11-25 |
EP0579648A1 (fr) | 1994-01-26 |
TW210333B (fr) | 1993-08-01 |
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