JPH06501624A - 腸定着ラクトバシラス - Google Patents
腸定着ラクトバシラスInfo
- Publication number
- JPH06501624A JPH06501624A JP5502759A JP50275993A JPH06501624A JP H06501624 A JPH06501624 A JP H06501624A JP 5502759 A JP5502759 A JP 5502759A JP 50275993 A JP50275993 A JP 50275993A JP H06501624 A JPH06501624 A JP H06501624A
- Authority
- JP
- Japan
- Prior art keywords
- lactobacillus
- strain
- ability
- intestinal mucosa
- strains
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
- C12R2001/245—Lactobacillus casei
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
- C12R2001/25—Lactobacillus plantarum
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/853—Lactobacillus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/853—Lactobacillus
- Y10S435/856—Lactobacillus casei
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/853—Lactobacillus
- Y10S435/857—Lactobacillus plantarum
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Surgical Instruments (AREA)
- Jellies, Jams, And Syrups (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (10)
- 1.インビボでヒトの腸粘膜にコロナイズ(colonize)し定着(est ablished)するようになる能力を有するラクトバシラスの菌株を単離す る方法であって、ラクトバシラスがヒト腸粘膜から単離され、適当な栄養培地中 で純粋培養(pure cultured)され、腸内でコロナイズし定着する ようになる能力について選択されることを特徴とする方法。
- 2.コロナイズし定着するようになる該能力が、経口投与、及び投与完了後少な くとも10日で腸粘膜上への出現の確認によって、試験されることを特徴とする 請求項1に記載の方法。
- 3.選択が、胆汁耐性、pH耐性、オートミールの発酵能力及び香味を産生する 能力の評価によって行われることを特徴とする請求項1又は2に記載の方法。
- 4.請求項1から3のいずれかに従って得られることを特徴とする、インビボで ヒト腸粘膜にコロナイズする能力を有するラクトバシラス菌株。
- 5.ラクトバシラス プランタラム(Lactobacillsplantar um)299 DS16595、ラクトバシラス カセイ エスエスピ ー.ラムノサス(Lactobacillus casei ssp.rham nosus)271DSM6594、 又は本質的に対応するREA−パターンを有するその変異体であることを特徴と する、インビボでヒト腸粘膜にコロナイズする能力を有するラクトバシラス菌株 。
- 6.胃腸管中の感染の予防または治療のための組成物であって、請求項1から3 のいずれかに従って得られた、インビボでヒトの腸粘膜にコロナイズし定着する ようになる能力を有するラクトバシラスの菌株と、慣用されている担体とを組合 わせて含むことを特徴とする組成物。
- 7.菌株 ラクトバシラス プランタラム(Lactobacillusplantaru m)299 DSH6595、ラクトバシラス カセイ エスエスピ ー.ラムノサス(Lactobacillus casei ssp.rham nosus)271DSM6594、 又は本質的に対応するREA−パターンを有するその変異体を含有することを特 徴とする、請求項6に記載の組成物。
- 8.ラクトバシラス菌株によって発酵された栄養溶液をベースとするオートミー ルであることを特徴とする、経口、小腸(enteral)又は直腸(rect al)投与のための請求項6又は7に記載の組成物。
- 9.外科手術に関するバクテリア感染の予防又は治療のための、抗生物質に代る 、請求項4に記載のラクトバシラス菌株によって発酵された栄養組成物の使用。
- 10.該菌株が、 ラクトバシラス プランタラム(Lactobacillusplantaru m)299 DSM6595、ラクトバシラス カセイ エスエスピー.ラムノ サス(Lactobacillus casei ssp.rhamnosus )271DSM6594、 又は本質的に対応するREA−パターンを有するその変異体であることを特徴と する、請求項9に記載の使用。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9102238A SE469875C (sv) | 1991-07-25 | 1991-07-25 | Stam av tarmkoloniserande Lactobacillus samt komposition för profylax eller behandling av infektioner i magtarmkanalen |
SE9102238 | 1991-07-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH06501624A true JPH06501624A (ja) | 1994-02-24 |
JP2742962B2 JP2742962B2 (ja) | 1998-04-22 |
Family
ID=20383375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5502759A Expired - Lifetime JP2742962B2 (ja) | 1991-07-25 | 1992-07-24 | 腸定着ラクトバシラス |
Country Status (13)
Country | Link |
---|---|
US (3) | US5474932A (ja) |
EP (1) | EP0554418B1 (ja) |
JP (1) | JP2742962B2 (ja) |
AT (1) | ATE164073T1 (ja) |
AU (1) | AU659669B2 (ja) |
CA (1) | CA2091557C (ja) |
DE (1) | DE69224814T2 (ja) |
DK (1) | DK0554418T3 (ja) |
ES (1) | ES2114565T3 (ja) |
FI (2) | FI109357B (ja) |
NO (1) | NO306699B1 (ja) |
SE (1) | SE469875C (ja) |
WO (1) | WO1993001823A1 (ja) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999064023A1 (fr) * | 1998-06-05 | 1999-12-16 | Wakamoto Pharmaceutical Co., Ltd. | Compositions contenant des bacteries lactiques, medicaments et aliments |
JP2002335953A (ja) * | 2001-05-15 | 2002-11-26 | Snow Brand Milk Prod Co Ltd | 新規乳酸菌株 |
JP2004525106A (ja) * | 2000-12-18 | 2004-08-19 | プロバイオヘルス・エルエルシー | ラクトバシラス−カゼイke01株から得られたプロバイオティック化合物 |
WO2005019438A1 (ja) * | 2003-08-21 | 2005-03-03 | Otsuka Pharmaceutical Co., Ltd. | 粘膜免疫賦活作用を有する乳酸菌 |
JP2007537998A (ja) * | 2003-12-19 | 2007-12-27 | ザ・アイムス・カンパニー | コンパニオンアニマルのためのプロバイオティク乳酸桿菌の使用方法 |
JP2012526551A (ja) * | 2009-05-14 | 2012-11-01 | プロビ アクチエボラグ | プロバイオティックジュース飲料 |
JP2013515051A (ja) * | 2009-12-22 | 2013-05-02 | プロビ アクティエボラーグ | 穀物ベースフラクション及びプロバイオティックを含む非発酵組成物、並びにそれらの使用 |
JP2015163643A (ja) * | 2005-09-28 | 2015-09-10 | ノルディスク リバランス アクティーゼルスカブ | 治療エフェクターとしてプロバイオティック細菌と発酵穀物を用いるibd及びibsの治療 |
WO2020246585A1 (ja) | 2019-06-05 | 2020-12-10 | 森永乳業株式会社 | 栄養組成物 |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5716615A (en) * | 1992-02-10 | 1998-02-10 | Renata Maria Anna Cavaliere Vesely | Dietary and pharmaceutical compositions containing lyophilized lactic bacteria, their preparation and use |
JP2789554B2 (ja) * | 1994-09-26 | 1998-08-20 | 全国農業協同組合連合会 | 免疫活性を有するアルカリ処理ヨーグルト粉末の製造法 |
US5733540A (en) * | 1995-03-08 | 1998-03-31 | Lee; Peter Poon-Hang | Protection from viral infection via colonization of mucosal membranes with genetically modified bacteria |
SE9501056D0 (sv) * | 1995-03-23 | 1995-03-23 | Probi Ab | Epithelial adherent lactobacilli |
KR100376954B1 (ko) * | 1995-07-31 | 2003-07-18 | 프로비 에이비 | 장에서집락화하는유산간균 |
AUPN907296A0 (en) * | 1996-04-02 | 1996-04-26 | Commonwealth Scientific And Industrial Research Organisation | Biocontrol agents for use in treatment of opportunistic infections |
ATE298363T1 (de) * | 1996-07-09 | 2005-07-15 | Nestle Sa | Verfahren zur sprühtrocknung |
GB9623068D0 (en) * | 1996-11-06 | 1997-01-08 | Cultech Limited | Microflora |
SE511524C2 (sv) * | 1997-06-02 | 1999-10-11 | Essum Ab | Lactobacillus casei rhamnosus-stam samt farmaceutisk beredning för bekämpning av patogena tarmbakterier |
SE510753C2 (sv) * | 1997-08-05 | 1999-06-21 | Probi Ab | Användning av en stam av Lactobacillus för tillverkning av ett läkemedel för reduktion av fibrinogenhalten i blod |
RO112995B1 (ro) * | 1997-08-05 | 1998-03-30 | Rodica Teodorescu | Produs medicamentos pentru terapia colonului |
SE511025C2 (sv) * | 1997-10-03 | 1999-07-26 | Probi Ab | Foderprodukt för häst omfattande Lactobacillus plantarum JI:1 samt Lactobacillus plantarum JI:1 och användning därav |
ES2279534T3 (es) * | 1997-12-12 | 2007-08-16 | KARL MULLER GMBH & CO. | Composicion para curado de salchichas crudas. |
PL347029A1 (en) * | 1998-10-01 | 2002-03-11 | Probi Ab | Reduction of oxidative stress factors |
FR2785809B1 (fr) | 1998-11-18 | 2001-01-12 | Gervais Danone Sa | Selection et utilisations de souches de bacteries lactiques modulatrices de l'immunite non-specifique |
PL348973A1 (en) | 1998-12-11 | 2002-06-17 | Urex Biotech Inc | Oral administration of lactobacillus for the treatment and prevention of urogenital infection |
US6696057B1 (en) | 1999-09-22 | 2004-02-24 | Lacpro Industries, Inc. | Composition and method for treatment of gastrointestinal disorders and hyperlipidemia |
TW588109B (en) * | 2000-07-29 | 2004-05-21 | Tcell Biotechnology Food Co Lt | Lactobacillus rhamnosus strain and uses thereof |
GB2369777B (en) * | 2000-10-05 | 2004-10-27 | St Ivel Ltd | Food products with antimicrobial lactic acid bacteria |
US7214370B2 (en) | 2000-12-18 | 2007-05-08 | Probiohealth, Llc | Prebiotic and preservative uses of oil-emulsified probiotic encapsulations |
CA2457092A1 (en) * | 2001-09-05 | 2003-03-20 | Vsl Pharmaceuticals, Inc. | Lactic acid bacteria comprising unmethylated cytosine-guanine dinucleotides for use in therapy |
GB0124580D0 (en) * | 2001-10-12 | 2001-12-05 | Univ Reading | New composition |
SE0103695D0 (sv) * | 2001-11-07 | 2001-11-07 | Thomas Boren | A novel non-antibiotic strategy against OGIP infections based on a cereal product |
AU2003285937A1 (en) * | 2002-10-22 | 2004-05-13 | University Of Vermont And State Agriculture College | Symbiotic food products comprising oats and methods for manufacturing the same |
SE527555C2 (sv) | 2003-04-04 | 2006-04-11 | Probi Ab | Anti-inflammatorisk komposition innehållande tannasproducerande Lactobacillusstammar |
CN1207382C (zh) * | 2003-04-11 | 2005-06-22 | 上海光明乳业股份有限公司 | 植物乳杆菌st-iii菌株及其在调节血脂方面的应用 |
US20050158294A1 (en) | 2003-12-19 | 2005-07-21 | The Procter & Gamble Company | Canine probiotic Bifidobacteria pseudolongum |
US8894991B2 (en) * | 2003-12-19 | 2014-11-25 | The Iams Company | Canine probiotic Lactobacilli |
US8877178B2 (en) | 2003-12-19 | 2014-11-04 | The Iams Company | Methods of use of probiotic bifidobacteria for companion animals |
US7125963B2 (en) | 2004-03-03 | 2006-10-24 | En N Tech Inc | Treatments for contaminant reduction in lactoferrin preparations and lactoferrin containing compositions |
WO2006046871A2 (en) * | 2004-10-29 | 2006-05-04 | N.V. Nutricia | Peri-operative composition comprising lactobacillus rhamnosus |
AR053805A1 (es) | 2005-05-31 | 2007-05-23 | Iams Company | Bifidobacterias probioticas para felinos |
CA2609617C (en) | 2005-05-31 | 2014-07-08 | The Iams Company | Feline probiotic lactobacilli |
SE529199C2 (sv) * | 2005-07-05 | 2007-05-29 | Probi Ab | Förstärkt absorption |
EP1769801A1 (en) * | 2005-09-28 | 2007-04-04 | Hans Israelsen | Use of a fermented cereal composition for the treatment of IBD and IBS |
EP1971231A4 (en) | 2005-11-17 | 2010-09-01 | Celac Sweden Ab | PROBIOTIC BREAD AND METHOD FOR THE PRODUCTION THEREOF |
PT1965809E (pt) | 2005-11-21 | 2009-12-15 | Bioatlantis Ltd | Composições para melhorar a saúde do intestino e o rendimento animal compreendendo beta-glucanos e alfa-fucanos |
FR2909526B1 (fr) * | 2006-12-08 | 2011-04-01 | Gervais Danone Sa | Produit alimentaire comprenant des probiotiques et un monoacide faible protone |
CA2673465A1 (en) | 2007-02-01 | 2008-08-07 | The Iams Company | Method for decreasing inflammation and stress in a mammal |
NZ579330A (en) * | 2007-03-01 | 2012-02-24 | Probi Ab | Use of lactobacillus plantarum for increasing bacterial diversity |
US9771199B2 (en) | 2008-07-07 | 2017-09-26 | Mars, Incorporated | Probiotic supplement, process for making, and packaging |
US10104903B2 (en) | 2009-07-31 | 2018-10-23 | Mars, Incorporated | Animal food and its appearance |
AU2011209407B2 (en) | 2010-01-28 | 2014-02-27 | Ab-Biotics S.A. | Probiotic composition for use in the treatment of bowel inflammation |
ITMI20110793A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri probiotici e composizione sinbiotica contenente gli stessi destinata alla alimentazione dei neonati. |
SI24570A (sl) | 2013-12-23 | 2015-06-30 | Medis D.O.O. | Novi sevi rodu Lactobacillus in njihova uporaba |
DE102013022189A1 (de) | 2013-12-31 | 2015-07-02 | Carlo Schmelzer | Funktionelles Getränk und Verfahren zu dessen Herstellung |
WO2019103198A1 (ko) | 2017-11-24 | 2019-05-31 | 주식회사 고바이오랩 | 락토바실러스 퍼멘텀 kbl 375 균주 및 그 용도 |
WO2019216662A1 (ko) | 2018-05-09 | 2019-11-14 | 주식회사 고바이오랩 | 락토바실러스 파라카제이 균주 및 그 용도 |
EP3798298A4 (en) | 2018-05-23 | 2022-05-11 | Kobiolabs, Inc. | LACTOBACILLUS GASSERI KBL697 STRAIN AND ITS USE |
WO2023002252A1 (en) | 2021-07-21 | 2023-01-26 | Bioatlantis Limited | Composition comprising beta-glucans and alpha-fucans for improving gut health and animal performance and methods of making the same |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4839281A (en) * | 1985-04-17 | 1989-06-13 | New England Medical Center Hospitals, Inc. | Lactobacillus strains and methods of selection |
AU624067B2 (en) * | 1986-12-12 | 1992-06-04 | Biorem C.C. | Preparation suitable for use in the treatment of enteric disorders |
DK686187D0 (da) * | 1987-12-23 | 1987-12-23 | Hansens Chr Bio Syst | Veterinaert praeparat |
SE463796B (sv) * | 1988-03-09 | 1991-01-28 | Carl Erik Albertsson | Foerfarande foer framstaellning av en naeringskomposition och daervid framstaelld naeringskomposition |
WO1991005851A1 (en) * | 1989-10-10 | 1991-05-02 | Tartusky Gosudarstvenny Universitet | Bacterium strain lactobacillus casei subsp. casei 37 for production of a bacterial biological preparation |
WO1991005850A1 (en) * | 1989-10-10 | 1991-05-02 | Tartusky Gosudarstvenny Universitet | Bacterium strain lactobacillus plantarum 38 for production of a bacterial biological preparation |
DK0768375T4 (da) * | 1992-07-06 | 2002-09-16 | Nestle Sa | Mælkesyrebakterier |
-
1991
- 1991-07-25 SE SE9102238A patent/SE469875C/sv not_active IP Right Cessation
-
1992
- 1992-07-24 CA CA002091557A patent/CA2091557C/en not_active Expired - Lifetime
- 1992-07-24 WO PCT/SE1992/000528 patent/WO1993001823A1/en active IP Right Grant
- 1992-07-24 JP JP5502759A patent/JP2742962B2/ja not_active Expired - Lifetime
- 1992-07-24 ES ES92916294T patent/ES2114565T3/es not_active Expired - Lifetime
- 1992-07-24 DE DE69224814T patent/DE69224814T2/de not_active Expired - Lifetime
- 1992-07-24 AU AU23709/92A patent/AU659669B2/en not_active Expired
- 1992-07-24 DK DK92916294T patent/DK0554418T3/da active
- 1992-07-24 AT AT92916294T patent/ATE164073T1/de active
- 1992-07-24 US US07/989,030 patent/US5474932A/en not_active Expired - Lifetime
- 1992-07-24 EP EP92916294A patent/EP0554418B1/en not_active Expired - Lifetime
-
1993
- 1993-03-22 FI FI931260A patent/FI109357B/fi not_active IP Right Cessation
- 1993-03-24 NO NO931085A patent/NO306699B1/no not_active IP Right Cessation
-
1995
- 1995-04-06 US US08/417,770 patent/US5587314A/en not_active Expired - Lifetime
- 1995-06-06 US US08/470,483 patent/US5591428A/en not_active Expired - Lifetime
-
2001
- 2001-12-19 FI FI20012509A patent/FI110611B/fi not_active IP Right Cessation
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999064023A1 (fr) * | 1998-06-05 | 1999-12-16 | Wakamoto Pharmaceutical Co., Ltd. | Compositions contenant des bacteries lactiques, medicaments et aliments |
JP2010195778A (ja) * | 2000-12-18 | 2010-09-09 | Probiohealth Llc | ラクトバシラス−カゼイke01株から得られたプロバイオティック化合物 |
JP2004525106A (ja) * | 2000-12-18 | 2004-08-19 | プロバイオヘルス・エルエルシー | ラクトバシラス−カゼイke01株から得られたプロバイオティック化合物 |
JP2002335953A (ja) * | 2001-05-15 | 2002-11-26 | Snow Brand Milk Prod Co Ltd | 新規乳酸菌株 |
JP4671384B2 (ja) * | 2001-05-15 | 2011-04-13 | 雪印乳業株式会社 | 新規乳酸菌株 |
US7842495B2 (en) | 2003-08-21 | 2010-11-30 | Otsuka Pharmaceutical Co., Ltd. | Lactic acid bacteria capable of stimulating mucosal immunity |
WO2005019438A1 (ja) * | 2003-08-21 | 2005-03-03 | Otsuka Pharmaceutical Co., Ltd. | 粘膜免疫賦活作用を有する乳酸菌 |
JP2007537998A (ja) * | 2003-12-19 | 2007-12-27 | ザ・アイムス・カンパニー | コンパニオンアニマルのためのプロバイオティク乳酸桿菌の使用方法 |
JP2015163643A (ja) * | 2005-09-28 | 2015-09-10 | ノルディスク リバランス アクティーゼルスカブ | 治療エフェクターとしてプロバイオティック細菌と発酵穀物を用いるibd及びibsの治療 |
JP2012526551A (ja) * | 2009-05-14 | 2012-11-01 | プロビ アクチエボラグ | プロバイオティックジュース飲料 |
US8679558B2 (en) | 2009-05-14 | 2014-03-25 | Probi Ab | Probiotic juice drink |
JP2013515051A (ja) * | 2009-12-22 | 2013-05-02 | プロビ アクティエボラーグ | 穀物ベースフラクション及びプロバイオティックを含む非発酵組成物、並びにそれらの使用 |
US11318181B2 (en) | 2009-12-22 | 2022-05-03 | Probi Ab | Non-fermented compositions comprising a cereal based fraction and a probiotic and uses thereof |
WO2020246585A1 (ja) | 2019-06-05 | 2020-12-10 | 森永乳業株式会社 | 栄養組成物 |
Also Published As
Publication number | Publication date |
---|---|
DE69224814T2 (de) | 1998-09-03 |
CA2091557A1 (en) | 1993-01-26 |
FI20012509A (fi) | 2001-12-19 |
DE69224814D1 (de) | 1998-04-23 |
EP0554418B1 (en) | 1998-03-18 |
ATE164073T1 (de) | 1998-04-15 |
FI931260A (fi) | 1993-03-22 |
US5591428A (en) | 1997-01-07 |
US5474932A (en) | 1995-12-12 |
NO306699B1 (no) | 1999-12-13 |
NO931085L (no) | 1993-03-24 |
JP2742962B2 (ja) | 1998-04-22 |
NO931085D0 (no) | 1993-03-24 |
SE9102238D0 (sv) | 1991-07-25 |
US5587314A (en) | 1996-12-24 |
DK0554418T3 (da) | 1999-01-11 |
SE469875C (sv) | 1997-02-05 |
FI931260A0 (fi) | 1993-03-22 |
CA2091557C (en) | 1999-12-21 |
FI110611B (fi) | 2003-02-28 |
FI109357B (fi) | 2002-07-15 |
EP0554418A1 (en) | 1993-08-11 |
SE469875B (sv) | 1993-10-04 |
ES2114565T3 (es) | 1998-06-01 |
AU2370992A (en) | 1993-02-23 |
AU659669B2 (en) | 1995-05-25 |
SE9102238L (sv) | 1993-01-26 |
WO1993001823A1 (en) | 1993-02-04 |
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