JPH0649649B2 - 腎臓障害の阻止治療薬 - Google Patents
腎臓障害の阻止治療薬Info
- Publication number
- JPH0649649B2 JPH0649649B2 JP60503369A JP50336985A JPH0649649B2 JP H0649649 B2 JPH0649649 B2 JP H0649649B2 JP 60503369 A JP60503369 A JP 60503369A JP 50336985 A JP50336985 A JP 50336985A JP H0649649 B2 JPH0649649 B2 JP H0649649B2
- Authority
- JP
- Japan
- Prior art keywords
- iloprost
- ccl
- medium
- cells
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 230000002792 vascular Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3427797.8 | 1984-07-25 | ||
| DE19843427797 DE3427797A1 (de) | 1984-07-25 | 1984-07-25 | Zytoprotektive wirkung von prostacyclin-derivaten an leber, bauchspeicheldruese und niere |
| PCT/DE1985/000245 WO1986000808A1 (fr) | 1984-07-25 | 1985-07-18 | Derives de prostacycline a action cytoprotectrice sur le foie, le pancreas et les reins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61502819A JPS61502819A (ja) | 1986-12-04 |
| JPH0649649B2 true JPH0649649B2 (ja) | 1994-06-29 |
Family
ID=6241773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60503369A Expired - Lifetime JPH0649649B2 (ja) | 1984-07-25 | 1985-07-18 | 腎臓障害の阻止治療薬 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5049582A (OSRAM) |
| EP (1) | EP0191792B1 (OSRAM) |
| JP (1) | JPH0649649B2 (OSRAM) |
| DE (3) | DE3448257C2 (OSRAM) |
| WO (1) | WO1986000808A1 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3631169A1 (de) * | 1986-09-11 | 1988-03-24 | Schering Ag | Prostacyclinderivate enthaltende mittel fuer die topische anwendung |
| DE3740838A1 (de) * | 1987-11-27 | 1989-06-08 | Schering Ag | Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel |
| ATE150311T1 (de) * | 1988-12-23 | 1997-04-15 | Teijin Ltd | Verwendung von isokarbacyclinen zur vorbeugung oder behandlung von organkrankheiten |
| US5364883A (en) * | 1988-12-23 | 1994-11-15 | Teijin Limited | Isocarbocyclins for the treatment of liver and kidney diseases |
| JPH089544B2 (ja) * | 1989-08-09 | 1996-01-31 | 株式会社上野製薬応用研究所 | 腸内排泄剤 |
| DE4135193C1 (OSRAM) * | 1991-10-22 | 1993-03-11 | Schering Ag Berlin Und Bergkamen, 1000 Berlin, De | |
| DE69228235T2 (de) * | 1991-10-25 | 1999-07-01 | Toray Industries, Inc., Tokio/Tokyo | Verwendung eines Mittels zur Herstellung eines Arzneimittels zur Behandlung von Lebererkrankung |
| DE69426295T2 (de) * | 1993-05-07 | 2001-04-05 | Chugai Seiyaku K.K., Tokio/Tokyo | Organkonservierungsmittel |
| DE10253623B4 (de) * | 2002-11-15 | 2006-03-09 | Justus-Liebig-Universität Giessen | Bioabbaubare kolloidale Partikel, insbesondere für pulmonale Applikationen |
| EP1628654B2 (en) | 2003-05-22 | 2019-12-04 | United Therapeutics Corporation | Compounds and methods for delivery of prostacyclin analogs |
| EP2043629A1 (en) * | 2006-07-18 | 2009-04-08 | Bayer Schering Pharma Aktiengesellschaft | 5-cyano-prostacyclin derivatives as agents for the treatment of autoimmune diseases |
| EP2094273B1 (en) * | 2006-11-16 | 2013-03-06 | Gemmus Pharma Inc. | EP2 and EP4 agonists as agents for the treatment of influenza A viral infection |
| US7776896B2 (en) | 2007-03-28 | 2010-08-17 | Bayer Schering Pharma Aktiengesellschaft | 5-cyano-prostacyclin derivatives as agents for the treatment of influenza a viral infection |
| CA3212313A1 (en) | 2013-03-14 | 2014-10-02 | United Therapeutics Corporation | Solid forms of treprostinil |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0011591A1 (de) * | 1978-10-19 | 1980-05-28 | Schering Aktiengesellschaft | Neue Prostanderivate, ihre Herstellung und sie enthaltende Arzneimittel |
| JPS58164512A (ja) * | 1982-03-25 | 1983-09-29 | Ono Pharmaceut Co Ltd | プロスタグランジン類似化合物を有効成分として含有する肝臓疾患治療剤 |
| JPS58203911A (ja) * | 1982-05-25 | 1983-11-28 | Ono Pharmaceut Co Ltd | プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2753244A1 (de) * | 1977-11-25 | 1979-06-07 | Schering Ag | Neue prostacyclinderivate und verfahren zu ihrer herstellung |
-
1984
- 1984-07-25 DE DE3448257A patent/DE3448257C2/de not_active Expired
- 1984-07-25 DE DE19843427797 patent/DE3427797A1/de active Granted
-
1985
- 1985-07-18 WO PCT/DE1985/000245 patent/WO1986000808A1/de not_active Ceased
- 1985-07-18 EP EP85903809A patent/EP0191792B1/de not_active Expired - Lifetime
- 1985-07-18 DE DE8585903809T patent/DE3585282D1/de not_active Expired - Lifetime
- 1985-07-18 JP JP60503369A patent/JPH0649649B2/ja not_active Expired - Lifetime
-
1989
- 1989-02-27 US US07/315,878 patent/US5049582A/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0011591A1 (de) * | 1978-10-19 | 1980-05-28 | Schering Aktiengesellschaft | Neue Prostanderivate, ihre Herstellung und sie enthaltende Arzneimittel |
| JPS58164512A (ja) * | 1982-03-25 | 1983-09-29 | Ono Pharmaceut Co Ltd | プロスタグランジン類似化合物を有効成分として含有する肝臓疾患治療剤 |
| JPS58203911A (ja) * | 1982-05-25 | 1983-11-28 | Ono Pharmaceut Co Ltd | プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| US5049582A (en) | 1991-09-17 |
| EP0191792A1 (de) | 1986-08-27 |
| JPS61502819A (ja) | 1986-12-04 |
| WO1986000808A1 (fr) | 1986-02-13 |
| DE3427797A1 (de) | 1986-02-06 |
| EP0191792B1 (de) | 1992-01-22 |
| DE3585282D1 (de) | 1992-03-05 |
| DE3448257C2 (en) | 1988-08-18 |
| DE3427797C2 (OSRAM) | 1988-08-11 |
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