JPH06271575A - ９Ｈ−イミダゾ［１，２−ａ］ベンズイミダゾール−３−アセトアミド誘導体、その製法および治療への応用 - Google Patents

９Ｈ−イミダゾ［１，２−ａ］ベンズイミダゾール−３−アセトアミド誘導体、その製法および治療への応用

Info

Publication number
JPH06271575A
JPH06271575A JP6002463A JP246394A JPH06271575A JP H06271575 A JPH06271575 A JP H06271575A JP 6002463 A JP6002463 A JP 6002463A JP 246394 A JP246394 A JP 246394A JP H06271575 A JPH06271575 A JP H06271575A
Authority
JP
Japan
Prior art keywords
group
compound
solvent
general formula
imidazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6002463A
Other languages
English (en)
Japanese (ja)
Inventor
Pascal George
パスカル・ジョルジュ
Peretti Danielle De
ダニエル・ドゥ・ペレッティ
Jocelyne Roy
ジョスリン・ロイ
Jean-Paul Schmitt
ジャン−ポール・シュミット
Mireille Sevrin
ミレーユ・セヴラン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9300337A external-priority patent/FR2700544B1/fr
Priority claimed from FR9309013A external-priority patent/FR2707987B1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of JPH06271575A publication Critical patent/JPH06271575A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP6002463A 1993-01-15 1994-01-14 ９Ｈ−イミダゾ［１，２−ａ］ベンズイミダゾール−３−アセトアミド誘導体、その製法および治療への応用 Pending JPH06271575A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9300337A FR2700544B1 (fr) 1993-01-15 1993-01-15 Dérivés de 9H-imidazo[1,2-a]benzimidazole-3-acétamide, leur préparation et leur application en thérapeutique.
FR9300337 1993-01-15
FR9309013 1993-07-22
FR9309013A FR2707987B1 (fr) 1993-07-22 1993-07-22 Dérivés de 9H-imidazo[1,2-a]benzimidazole-3-acétamide, leur préparation et leur application en thérapeutique .

Publications (1)

Publication Number Publication Date
JPH06271575A true JPH06271575A (ja) 1994-09-27

Family

ID=26230029

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6002463A Pending JPH06271575A (ja) 1993-01-15 1994-01-14 ９Ｈ−イミダゾ［１，２−ａ］ベンズイミダゾール−３−アセトアミド誘導体、その製法および治療への応用

Country Status (16)

Country Link
US (1) US5466706A (https=)
EP (1) EP0607076A1 (https=)
JP (1) JPH06271575A (https=)
CN (1) CN1097743A (https=)
AU (1) AU665137B2 (https=)
CA (1) CA2113490A1 (https=)
CZ (1) CZ9394A3 (https=)
FI (1) FI940186A7 (https=)
HU (1) HUT70407A (https=)
IL (1) IL108343A0 (https=)
NO (1) NO940130L (https=)
NZ (1) NZ250679A (https=)
PL (1) PL301901A1 (https=)
RU (1) RU94000725A (https=)
SK (1) SK4694A3 (https=)
TW (1) TW253886B (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006516139A (ja) * 2002-12-18 2006-06-22 マリンクロッド・インコーポレイテッド ヘテロアリールアセトアミド化合物の合成
JP2007537212A (ja) * 2004-05-11 2007-12-20 サノフイ−アベンテイス ２ｈ−又は３ｈ−ベンゾ［ｅ］インダゾール１−イルカルバメート誘導体、これらの調製及び治療的使用
JP2008503578A (ja) * 2004-06-22 2008-02-07 マリンクロッド・インコーポレイテッド 水分含量を減少させた反応混合物からのヘテロアリールアセトアミドの合成
JP2009530300A (ja) * 2006-03-17 2009-08-27 アムビト ビオスシエンセス コルポラチオン 疾患を治療するためのイミダゾロチアゾール化合物

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2719843B1 (fr) * 1994-05-10 1996-06-07 Synthelabo Dérivés de 5,6-dihydro-4h-imidazo [2',1':2,3] imidazo-[4,5,1-ij] quinoléine et de 4,5-dihydroimidazo [1,2-a] pyrrolo-[1,2,3-cd] benzimidazole, leur préparation et leur application en thérapeutique.
FR2741073B1 (fr) * 1995-11-09 1997-12-12 Synthelabo Derives de 4,5-dihydroimidazo(1,2-a)pyrrolo(1,2,3-cd) benzimidazole, leur preparation et leur application en therapeutique
GB9702524D0 (en) * 1997-02-07 1997-03-26 Merck Sharp & Dohme Therapeutic agents
FR2759698B1 (fr) * 1997-02-20 1999-03-19 Synthelabo Derives de 1,4-diphenylimidazole-5-acetamide, leur preparation et leur application en therapeutique
EP1318988A2 (en) * 2000-09-11 2003-06-18 Sepracor, Inc. Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission)
KR20040034594A (ko) * 2001-01-26 2004-04-28 브리스톨-마이어스스퀴브컴파니 코르티코트로핀 방출 인자 억제제로서의 이미다졸릴 유도체
EP2201018B1 (en) 2007-09-19 2016-03-16 Ambit Biosciences Corporation Solid forms comprising n-(5-tert-butyl-isoxazol-3-yl)-n'-{4-ý7-(2-morpholin-4-yl-ethoxy)imidazoý2,1-b¨ý1,3¨benzothiazol-2-yl¨phenyl}urea, compositions thereof, and uses therewith

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732243A (en) * 1970-06-23 1973-05-08 Sankyo Co 2-(p-bromophenyl)-9-dimethyl-amino-propyl-9h-imidazo(1,2-a)benzimidazole
GB1484615A (en) * 1974-11-23 1977-09-01 Lepetit Spa Tricyclic n-containing derivatives
FR2568879B1 (fr) * 1984-08-07 1986-12-12 Synthelabo Imidazo(1,2-a)quinolines, leur preparation et leur application en therapeutique
US4675323A (en) * 1985-08-06 1987-06-23 Synthelabo Imidazo(1,2-a)quinoline derivatives useful as anxiolytic agents
US5240944A (en) * 1988-12-28 1993-08-31 Kotobuki Seiyaku Co. Ltd. Cyclic guanidine derivatives, anti-ulceratives and method of manufacturing the same

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006516139A (ja) * 2002-12-18 2006-06-22 マリンクロッド・インコーポレイテッド ヘテロアリールアセトアミド化合物の合成
JP2007537212A (ja) * 2004-05-11 2007-12-20 サノフイ−アベンテイス ２ｈ−又は３ｈ−ベンゾ［ｅ］インダゾール１−イルカルバメート誘導体、これらの調製及び治療的使用
JP2008503578A (ja) * 2004-06-22 2008-02-07 マリンクロッド・インコーポレイテッド 水分含量を減少させた反応混合物からのヘテロアリールアセトアミドの合成
JP2009530300A (ja) * 2006-03-17 2009-08-27 アムビト ビオスシエンセス コルポラチオン 疾患を治療するためのイミダゾロチアゾール化合物
JP2011037858A (ja) * 2006-03-17 2011-02-24 Ambit Biosciences Corp 疾患を治療するためのイミダゾロチアゾール化合物

Also Published As

Publication number Publication date
AU665137B2 (en) 1995-12-14
SK4694A3 (en) 1995-02-08
HUT70407A (en) 1995-10-30
NO940130D0 (no) 1994-01-14
RU94000725A (ru) 1997-05-27
FI940186A7 (fi) 1994-07-16
PL301901A1 (en) 1994-07-25
US5466706A (en) 1995-11-14
NZ250679A (en) 1995-07-26
TW253886B (https=) 1995-08-11
CA2113490A1 (en) 1994-07-16
HU9400109D0 (en) 1994-05-30
IL108343A0 (en) 1994-04-12
CN1097743A (zh) 1995-01-25
FI940186A0 (fi) 1994-01-14
EP0607076A1 (fr) 1994-07-20
NO940130L (no) 1994-07-18
AU5317794A (en) 1995-05-25
CZ9394A3 (en) 1994-08-17

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