JPH0615556B2 - ４―カルバモイル―１―β―Ｄ―リボフラノシル―イミダゾリウム―５―オレイト無水結晶 - Google Patents

４―カルバモイル―１―β―Ｄ―リボフラノシル―イミダゾリウム―５―オレイト無水結晶

Info

Publication number
JPH0615556B2
JPH0615556B2 JP1291078A JP29107889A JPH0615556B2 JP H0615556 B2 JPH0615556 B2 JP H0615556B2 JP 1291078 A JP1291078 A JP 1291078A JP 29107889 A JP29107889 A JP 29107889A JP H0615556 B2 JPH0615556 B2 JP H0615556B2
Authority
JP
Japan
Prior art keywords
mizoribine
crystal
crystals
anhydrous
monohydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP1291078A
Other languages
English (en)
Japanese (ja)
Other versions
JPH03157393A (ja
Inventor
真二 尾関
信一 中津川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17764149&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH0615556(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP1291078A priority Critical patent/JPH0615556B2/ja
Priority to TW079108909A priority patent/TW199164B/zh
Priority to DE69025859T priority patent/DE69025859T2/de
Priority to EP90120255A priority patent/EP0428879B1/en
Priority to AT90120255T priority patent/ATE135364T1/de
Priority to CA002028416A priority patent/CA2028416C/en
Priority to AU64939/90A priority patent/AU631256B2/en
Priority to IE381790A priority patent/IE62718B1/en
Priority to KR1019900017154A priority patent/KR960003618B1/ko
Priority to NZ235899A priority patent/NZ235899A/en
Publication of JPH03157393A publication Critical patent/JPH03157393A/ja
Publication of JPH0615556B2 publication Critical patent/JPH0615556B2/ja
Priority to US08/231,011 priority patent/US5442051A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP1291078A 1989-11-10 1989-11-10 ４―カルバモイル―１―β―Ｄ―リボフラノシル―イミダゾリウム―５―オレイト無水結晶 Expired - Lifetime JPH0615556B2 (ja)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP1291078A JPH0615556B2 (ja) 1989-11-10 1989-11-10 ４―カルバモイル―１―β―Ｄ―リボフラノシル―イミダゾリウム―５―オレイト無水結晶
TW079108909A TW199164B (enExample) 1989-11-10 1990-10-22
DE69025859T DE69025859T2 (de) 1989-11-10 1990-10-22 Wasserfreie Kristalle von 4-Carbamoyl-1-beta-D-ribofuranosyl-imidazolium-5-Olat
EP90120255A EP0428879B1 (en) 1989-11-10 1990-10-22 Anhydrous crystal of 4-carbamoyl-1-beta-D-ribofuranosyl imidazolium-5-olate
AT90120255T ATE135364T1 (de) 1989-11-10 1990-10-22 Wasserfreie kristalle von 4-carbamoyl-1-beta-d- ribofuranosyl-imidazolium-5-olat
CA002028416A CA2028416C (en) 1989-11-10 1990-10-23 Anhydrous crystal of 4-carbamoyl-1-.beta.-d-ribofuranosyl imidazolium-5-oleate
IE381790A IE62718B1 (en) 1989-11-10 1990-10-24 Anhydrous crystal of 4-carbomoyl-1-beta-d-ribofuranosyl imidazolium-5-olate
AU64939/90A AU631256B2 (en) 1989-11-10 1990-10-24 Anhydrous crystal of 4-carbamoyl-1-beta-d-ribofuranosyl imidazolium-5-oleate
KR1019900017154A KR960003618B1 (ko) 1989-11-10 1990-10-25 4-카르바모일-1-β-D-리보푸라노실 이미다졸륨-5-올레이트 무수결정
NZ235899A NZ235899A (en) 1989-11-10 1990-10-30 Anhydrous crystals of 4-carbamoyl-1-beta-d-ribofuranosyl imidazolium-5-olate and method of preparation
US08/231,011 US5442051A (en) 1989-11-10 1994-04-21 Anhydrous crystal of 4-carbamoyl-1-β-D-ribofuranosyl imidazolium-5-oleate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1291078A JPH0615556B2 (ja) 1989-11-10 1989-11-10 ４―カルバモイル―１―β―Ｄ―リボフラノシル―イミダゾリウム―５―オレイト無水結晶

Publications (2)

Publication Number Publication Date
JPH03157393A JPH03157393A (ja) 1991-07-05
JPH0615556B2 true JPH0615556B2 (ja) 1994-03-02

Family

ID=17764149

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1291078A Expired - Lifetime JPH0615556B2 (ja) 1989-11-10 1989-11-10 ４―カルバモイル―１―β―Ｄ―リボフラノシル―イミダゾリウム―５―オレイト無水結晶

Country Status (11)

Country Link
US (1) US5442051A (enExample)
EP (1) EP0428879B1 (enExample)
JP (1) JPH0615556B2 (enExample)
KR (1) KR960003618B1 (enExample)
AT (1) ATE135364T1 (enExample)
AU (1) AU631256B2 (enExample)
CA (1) CA2028416C (enExample)
DE (1) DE69025859T2 (enExample)
IE (1) IE62718B1 (enExample)
NZ (1) NZ235899A (enExample)
TW (1) TW199164B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4818994B2 (ja) * 2000-01-26 2011-11-16 旭化成ファーマ株式会社 色調変化の改善されたミゾリビン錠剤
TWI275394B (en) * 2000-01-26 2007-03-11 Asahi Chemical Corp Mizoribin tablet improved with color tone change
JP2001300293A (ja) * 2000-04-25 2001-10-30 Nipro Corp 無機無水物または有機無水物の製造法
CN103450300B (zh) * 2013-09-12 2015-10-28 华北制药集团新药研究开发有限责任公司 一种咪唑立宾的提纯方法
US11365170B2 (en) 2018-07-13 2022-06-21 Kyowa Hakko Bio Co., Ltd. Non-solvate crystal of eucomic acid and method for producing same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888843A (en) * 1973-06-12 1975-06-10 Toyo Jozo Kk 4-carbamoyl-1-' -d-ribofuranosylimidazolium-5-olate
JPS5652038B2 (enExample) * 1974-03-09 1981-12-09
JPS511693A (en) * 1974-06-21 1976-01-08 Toyo Jozo Kk 44 karubamoiru 11 beetaa dd ribofuranoshiiru imidazoriumu 55 oreitonoseizoho
JPS606634B2 (ja) * 1981-07-16 1985-02-19 キッコーマン株式会社 サイクリツク−３′，５′−グアニル酸の製造法
JPH03504728A (ja) * 1989-01-24 1991-10-17 ジェンシア・ファーマシュウティカルズ，インコーポレイテッド Ａｉｃａリボシドの放出および血液グルコースの低減のための化合物および方法
IL99124A (en) * 1990-08-10 1998-02-22 Gensia Pharma Substituted imidazole analogs of aica riboside

Also Published As

Publication number Publication date
KR960003618B1 (ko) 1996-03-20
EP0428879A3 (en) 1991-08-07
US5442051A (en) 1995-08-15
TW199164B (enExample) 1993-02-01
CA2028416A1 (en) 1991-05-11
DE69025859D1 (de) 1996-04-18
AU631256B2 (en) 1992-11-19
ATE135364T1 (de) 1996-03-15
EP0428879B1 (en) 1996-03-13
EP0428879A2 (en) 1991-05-29
IE903817A1 (en) 1991-05-22
CA2028416C (en) 1999-09-07
AU6493990A (en) 1991-05-16
KR910009723A (ko) 1991-06-28
DE69025859T2 (de) 1996-10-31
NZ235899A (en) 1991-12-23
JPH03157393A (ja) 1991-07-05
IE62718B1 (en) 1995-02-22

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