JPH0586951B2 - - Google Patents
Info
- Publication number
- JPH0586951B2 JPH0586951B2 JP86158634A JP15863486A JPH0586951B2 JP H0586951 B2 JPH0586951 B2 JP H0586951B2 JP 86158634 A JP86158634 A JP 86158634A JP 15863486 A JP15863486 A JP 15863486A JP H0586951 B2 JPH0586951 B2 JP H0586951B2
- Authority
- JP
- Japan
- Prior art keywords
- formula
- methyl
- pharmaceutically acceptable
- compound according
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Pyridine Compounds (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858517051A GB8517051D0 (en) | 1985-07-05 | 1985-07-05 | Chemical compounds |
| GB8517051 | 1985-07-05 | ||
| GB868606853A GB8606853D0 (en) | 1986-03-20 | 1986-03-20 | Chemical compounds |
| GB8606853 | 1986-03-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6212765A JPS6212765A (ja) | 1987-01-21 |
| JPH0586951B2 true JPH0586951B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-12-14 |
Family
ID=26289481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61158634A Granted JPS6212765A (ja) | 1985-07-05 | 1986-07-04 | ベンゼン誘導体 |
Country Status (16)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4962110A (en) * | 1985-03-12 | 1990-10-09 | Smith Kline & French Laboratories Limited | Pyridazinone derivatives |
| US4970210A (en) * | 1987-07-17 | 1990-11-13 | Abbott Laboratories | Triazinone lipoxygenase compounds |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3975388A (en) * | 1971-02-22 | 1976-08-17 | Bdh Pharmaceuticals Limited | Pyridazinones |
| US4088762A (en) * | 1971-02-22 | 1978-05-09 | Bdh Pharmaceuticals Limited | 6-(P-PIPERAZINO)-PHENYL-4,5-DIHYDRO-3(2H)pyridazinones |
| BE790106A (fr) * | 1971-10-14 | 1973-04-13 | Basf Ag | Dihydropyridazones, leur preparation et leurs utilisations therapeutiques |
| EP0059688B1 (de) * | 1981-03-04 | 1985-05-15 | Ciba-Geigy Ag | Pyridazinone, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend diese Verbindungen und deren Verwendung |
| HU190412B (en) * | 1981-09-17 | 1986-09-29 | Warner-Lambert Co,Us | Process for producing substituted 4,5-dihiydro-6-bracket-substituted-bracket closed-phenyl-3-bracket-2h-bracket closed-pyridazinones and 6-bracket-substituted-bracket closed-phenyl-3-bracket-2h-bracket closed-pyridazinones |
| US4353905A (en) * | 1981-09-17 | 1982-10-12 | Warner-Lambert Company | Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones |
| IT1171604B (it) * | 1981-10-22 | 1987-06-10 | Roussel Maestretti Spa | Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione |
| JPS58113180A (ja) * | 1981-12-28 | 1983-07-05 | Mitsui Toatsu Chem Inc | ピリダジノン誘導体 |
| JPS58162577A (ja) * | 1982-03-19 | 1983-09-27 | Sankyo Co Ltd | ６−フエニルピリダジノン化合物の製造法 |
| DE3212304A1 (de) * | 1982-04-02 | 1983-10-06 | Nattermann A & Cie | Imidazolylphenyl-tetrahydropyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| ES532337A0 (es) * | 1983-05-11 | 1985-12-01 | Byk Gulden Lomberg Chem Fab | Procedimiento para la preparacion de 6-aril-3 (2h)piridazinonas |
| US4599332A (en) * | 1983-12-07 | 1986-07-08 | Warner-Lambert Company | 4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]-ethenyl]-3(2H)-pyridazinones and related compounds |
| JPS60197672A (ja) * | 1984-03-16 | 1985-10-07 | Mitsubishi Chem Ind Ltd | ビリダジノン誘導体またはその塩類 |
| DE3425632A1 (de) * | 1984-07-12 | 1986-01-16 | Basf Ag, 6700 Ludwigshafen | (pyrrol-1-yl)-phenyl-dihydropyridazinone, ihre herstellung und verwendung |
| US4816454A (en) * | 1984-09-21 | 1989-03-28 | Cassella Aktiengesellschaft | 4,5-dihydro-3(2H)-pyridazinones and their pharmacological use |
| US4631279A (en) * | 1984-10-15 | 1986-12-23 | Eli Lilly And Company | 6-(pyridinylphenyl)dihydropyridazinones as inotropic agents |
-
1986
- 1986-06-30 IL IL79280A patent/IL79280A/xx unknown
- 1986-07-01 PT PT82876A patent/PT82876B/pt unknown
- 1986-07-01 GR GR861719A patent/GR861719B/el unknown
- 1986-07-01 US US06/880,849 patent/US4904664A/en not_active Expired - Fee Related
- 1986-07-02 AU AU59488/86A patent/AU580677B2/en not_active Ceased
- 1986-07-03 DK DK316986A patent/DK316986A/da not_active Application Discontinuation
- 1986-07-03 NZ NZ216741A patent/NZ216741A/xx unknown
- 1986-07-04 AT AT86305187T patent/ATE56440T1/de not_active IP Right Cessation
- 1986-07-04 ES ES8600129A patent/ES2000209A6/es not_active Expired
- 1986-07-04 EP EP86305187A patent/EP0208517B1/en not_active Expired - Lifetime
- 1986-07-04 DE DE8686305187T patent/DE3674094D1/de not_active Expired - Lifetime
- 1986-07-04 FI FI862840A patent/FI862840L/fi not_active Application Discontinuation
- 1986-07-04 JP JP61158634A patent/JPS6212765A/ja active Granted
- 1986-07-04 NO NO862723A patent/NO862723L/no unknown
- 1986-07-04 HU HU862821A patent/HUT41393A/hu unknown
- 1986-07-05 CN CN198686105663A patent/CN86105663A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NZ216741A (en) | 1988-10-28 |
| US4904664A (en) | 1990-02-27 |
| CN86105663A (zh) | 1987-01-21 |
| FI862840A7 (fi) | 1987-01-06 |
| PT82876B (en) | 1988-11-03 |
| ATE56440T1 (de) | 1990-09-15 |
| IL79280A (en) | 1990-07-12 |
| GR861719B (en) | 1986-11-04 |
| DE3674094D1 (de) | 1990-10-18 |
| JPS6212765A (ja) | 1987-01-21 |
| DK316986D0 (da) | 1986-07-03 |
| EP0208517A2 (en) | 1987-01-14 |
| EP0208517A3 (en) | 1988-03-23 |
| PT82876A (en) | 1986-08-01 |
| AU5948886A (en) | 1987-01-08 |
| DK316986A (da) | 1987-01-06 |
| FI862840A0 (fi) | 1986-07-04 |
| AU580677B2 (en) | 1989-01-27 |
| NO862723L (no) | 1987-01-06 |
| EP0208517B1 (en) | 1990-09-12 |
| ES2000209A6 (es) | 1988-01-16 |
| HUT41393A (en) | 1987-04-28 |
| NO862723D0 (no) | 1986-07-04 |
| FI862840L (fi) | 1987-01-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4666908A (en) | 5-Substituted pyrazolo[4,3-d]pyrimidine-7-ones and methods of use | |
| RU2142946C1 (ru) | Производные пиразола и фармацевтическая композиция, содержащая их | |
| RU2007403C1 (ru) | Способ получения пиразолпиридинового производного или его соли | |
| KR920006781B1 (ko) | 디하이드로 피리다진온 유도체를 제조하는 방법 | |
| US4613603A (en) | Compounds with a nitrogen-containing heterocyclic nucleus, and drugs in which they are present | |
| TW200902006A (en) | Fast dissociating dopamine 2 receptor antagonists | |
| JPS5989679A (ja) | ピラゾロ〔３，４−ｂ〕ピリジン誘導体類およびそれらの製造法 | |
| EP0208518B1 (en) | 6-phenyl-pyridazinyl compounds | |
| JPH03170465A (ja) | ピリダジン誘導体、その製造方法及び該誘導体を含有する医薬組成物 | |
| EP0201988B1 (en) | Dihydropyridazinone derivatives | |
| US4652565A (en) | Piperazine derivatives, their production and pharmaceutical compositions containing them | |
| Sircar et al. | Cardiotonic agents. 5. 1, 2-Dihydro-5-[4-(1H-imidazol-1-yl) phenyl]-6-methyl-2-oxo-3-pyridinecarbonitriles and related compounds. Synthesis and inotropic activity | |
| CA1251448A (en) | Pyridazinone derivatives | |
| JPH0586951B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| US4766123A (en) | Methylamidine compounds | |
| US4755511A (en) | Tricyclic pyridazinone compounds | |
| JP4628107B2 (ja) | 置換された１ｈ−ピリジン−２−オン誘導体 | |
| US4962110A (en) | Pyridazinone derivatives | |
| JPS61212583A (ja) | ２‐アミノピリミジノン誘導体 | |
| EP0197664A2 (en) | 2-Aminopyrimidinone derivatives | |
| CA1048496A (en) | Process for preparing 2-oxo-1,2,3,4-tetrahydropyrido (2,3-d) pyrimidines | |
| JPS61212582A (ja) | ジヒドロピリダジノン誘導体 | |
| JPS61129179A (ja) | １−ベンズオキセピン−５−オン誘導体 | |
| JPS61221177A (ja) | シアノアルカンイミドアミド化合物 | |
| JPS6212764A (ja) | ジヒドロピリダジノン誘導体 |