DE3674094D1 - 6-oxo-pyridazinyl-verbindungen. - Google Patents

6-oxo-pyridazinyl-verbindungen.

Info

Publication number
DE3674094D1
DE3674094D1 DE8686305187T DE3674094T DE3674094D1 DE 3674094 D1 DE3674094 D1 DE 3674094D1 DE 8686305187 T DE8686305187 T DE 8686305187T DE 3674094 T DE3674094 T DE 3674094T DE 3674094 D1 DE3674094 D1 DE 3674094D1
Authority
DE
Germany
Prior art keywords
compounds
oxo
methyl
hydrogen
pyridazinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686305187T
Other languages
English (en)
Inventor
Hunter Douglas Prain
Brian Herbert Warrington
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
GlaxoSmithKline LLC
Original Assignee
Smith Kline and French Laboratories Ltd
GlaxoSmithKline LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858517051A external-priority patent/GB8517051D0/en
Priority claimed from GB868606853A external-priority patent/GB8606853D0/en
Application filed by Smith Kline and French Laboratories Ltd, GlaxoSmithKline LLC filed Critical Smith Kline and French Laboratories Ltd
Application granted granted Critical
Publication of DE3674094D1 publication Critical patent/DE3674094D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
DE8686305187T 1985-07-05 1986-07-04 6-oxo-pyridazinyl-verbindungen. Expired - Fee Related DE3674094D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858517051A GB8517051D0 (en) 1985-07-05 1985-07-05 Chemical compounds
GB868606853A GB8606853D0 (en) 1986-03-20 1986-03-20 Chemical compounds

Publications (1)

Publication Number Publication Date
DE3674094D1 true DE3674094D1 (de) 1990-10-18

Family

ID=26289481

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686305187T Expired - Fee Related DE3674094D1 (de) 1985-07-05 1986-07-04 6-oxo-pyridazinyl-verbindungen.

Country Status (16)

Country Link
US (1) US4904664A (de)
EP (1) EP0208517B1 (de)
JP (1) JPS6212765A (de)
CN (1) CN86105663A (de)
AT (1) ATE56440T1 (de)
AU (1) AU580677B2 (de)
DE (1) DE3674094D1 (de)
DK (1) DK316986A (de)
ES (1) ES2000209A6 (de)
FI (1) FI862840A (de)
GR (1) GR861719B (de)
HU (1) HUT41393A (de)
IL (1) IL79280A (de)
NO (1) NO862723L (de)
NZ (1) NZ216741A (de)
PT (1) PT82876B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962110A (en) * 1985-03-12 1990-10-09 Smith Kline & French Laboratories Limited Pyridazinone derivatives
US4970210A (en) * 1987-07-17 1990-11-13 Abbott Laboratories Triazinone lipoxygenase compounds

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975388A (en) * 1971-02-22 1976-08-17 Bdh Pharmaceuticals Limited Pyridazinones
US4088762A (en) * 1971-02-22 1978-05-09 Bdh Pharmaceuticals Limited 6-(P-PIPERAZINO)-PHENYL-4,5-DIHYDRO-3(2H)pyridazinones
BE790106A (fr) * 1971-10-14 1973-04-13 Basf Ag Dihydropyridazones, leur preparation et leurs utilisations therapeutiques
EP0059688B1 (de) * 1981-03-04 1985-05-15 Ciba-Geigy Ag Pyridazinone, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend diese Verbindungen und deren Verwendung
HU190412B (en) * 1981-09-17 1986-09-29 Warner-Lambert Co,Us Process for producing substituted 4,5-dihiydro-6-bracket-substituted-bracket closed-phenyl-3-bracket-2h-bracket closed-pyridazinones and 6-bracket-substituted-bracket closed-phenyl-3-bracket-2h-bracket closed-pyridazinones
US4353905A (en) * 1981-09-17 1982-10-12 Warner-Lambert Company Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones
IT1171604B (it) * 1981-10-22 1987-06-10 Roussel Maestretti Spa Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta' farmacologiche e loro procedimento di preparazione
JPS58113180A (ja) * 1981-12-28 1983-07-05 Mitsui Toatsu Chem Inc ピリダジノン誘導体
JPS58162577A (ja) * 1982-03-19 1983-09-27 Sankyo Co Ltd ６−フエニルピリダジノン化合物の製造法
DE3212304A1 (de) * 1982-04-02 1983-10-06 Nattermann A & Cie Imidazolylphenyl-tetrahydropyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GR82072B (de) * 1983-05-11 1984-12-13 Byk Gulden Lomberg Chem Fab
US4599332A (en) * 1983-12-07 1986-07-08 Warner-Lambert Company 4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]-ethenyl]-3(2H)-pyridazinones and related compounds
JPS60197672A (ja) * 1984-03-16 1985-10-07 Mitsubishi Chem Ind Ltd ビリダジノン誘導体またはその塩類
DE3425632A1 (de) * 1984-07-12 1986-01-16 Basf Ag, 6700 Ludwigshafen (pyrrol-1-yl)-phenyl-dihydropyridazinone, ihre herstellung und verwendung
US4816454A (en) * 1984-09-21 1989-03-28 Cassella Aktiengesellschaft 4,5-dihydro-3(2H)-pyridazinones and their pharmacological use
US4631279A (en) * 1984-10-15 1986-12-23 Eli Lilly And Company 6-(pyridinylphenyl)dihydropyridazinones as inotropic agents

Also Published As

Publication number Publication date
FI862840A0 (fi) 1986-07-04
DK316986A (da) 1987-01-06
ATE56440T1 (de) 1990-09-15
EP0208517A3 (en) 1988-03-23
FI862840A (fi) 1987-01-06
HUT41393A (en) 1987-04-28
PT82876A (en) 1986-08-01
AU5948886A (en) 1987-01-08
IL79280A (en) 1990-07-12
ES2000209A6 (es) 1988-01-16
EP0208517A2 (de) 1987-01-14
CN86105663A (zh) 1987-01-21
JPH0586951B2 (de) 1993-12-14
EP0208517B1 (de) 1990-09-12
NO862723D0 (no) 1986-07-04
DK316986D0 (da) 1986-07-03
PT82876B (en) 1988-11-03
JPS6212765A (ja) 1987-01-21
NZ216741A (en) 1988-10-28
US4904664A (en) 1990-02-27
GR861719B (en) 1986-11-04
NO862723L (no) 1987-01-06
AU580677B2 (en) 1989-01-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee