JPH057996B2 - - Google Patents

Info

Publication number
JPH057996B2
JPH057996B2 JP18730384A JP18730384A JPH057996B2 JP H057996 B2 JPH057996 B2 JP H057996B2 JP 18730384 A JP18730384 A JP 18730384A JP 18730384 A JP18730384 A JP 18730384A JP H057996 B2 JPH057996 B2 JP H057996B2
Authority
JP
Japan
Prior art keywords
ifn
dna
protein
cysteine
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP18730384A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6128384A (ja
Inventor
Efu Maaku Debitsuto
Esu Rin Reo
Yu Ru Shida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of JPS6128384A publication Critical patent/JPS6128384A/ja
Publication of JPH057996B2 publication Critical patent/JPH057996B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP18730384A 1982-10-19 1984-09-08 変形されたインターフェロン―βをコードするＤＮＡ、このＤＮＡを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌 Granted JPS6128384A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43515482A 1982-10-19 1982-10-19
US435154 1982-10-19
US486162 1983-04-15

Publications (2)

Publication Number Publication Date
JPS6128384A JPS6128384A (ja) 1986-02-08
JPH057996B2 true JPH057996B2 (enrdf_load_stackoverflow) 1993-01-29

Family

ID=23727220

Family Applications (4)

Application Number Title Priority Date Filing Date
JP58195931A Granted JPS5993093A (ja) 1982-10-19 1983-10-19 変形されたインターロイキン―２及びその製造方法
JP18730384A Granted JPS6128384A (ja) 1982-10-19 1984-09-08 変形されたインターフェロン―βをコードするＤＮＡ、このＤＮＡを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌
JP18730484A Pending JPS6128394A (ja) 1982-10-19 1984-09-08 部位特定突然変異用オリゴヌクレオチド
JP18730284A Granted JPS6128393A (ja) 1982-10-19 1984-09-08 変形されたインターロイキン―２をコードするｄｎａ、このｄｎａを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP58195931A Granted JPS5993093A (ja) 1982-10-19 1983-10-19 変形されたインターロイキン―２及びその製造方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP18730484A Pending JPS6128394A (ja) 1982-10-19 1984-09-08 部位特定突然変異用オリゴヌクレオチド
JP18730284A Granted JPS6128393A (ja) 1982-10-19 1984-09-08 変形されたインターロイキン―２をコードするｄｎａ、このｄｎａを含有するプラスミド及びこのプラスミドにより形質転換された大腸菌

Country Status (4)

Country Link
JP (4) JPS5993093A (enrdf_load_stackoverflow)
IL (1) IL90047A (enrdf_load_stackoverflow)
IN (1) IN161992B (enrdf_load_stackoverflow)
ZA (1) ZA837789B (enrdf_load_stackoverflow)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL76360A0 (en) 1984-09-26 1986-01-31 Takeda Chemical Industries Ltd Mutual separation of proteins
JP2675294B2 (ja) * 1984-10-15 1997-11-12 カイロン コーポレイション ヒト腫瘍壊死因子
FI862531A0 (fi) * 1984-10-15 1986-06-13 Cetus Corp Tumoernekrosisfaktor.
US4572798A (en) * 1984-12-06 1986-02-25 Cetus Corporation Method for promoting disulfide bond formation in recombinant proteins
JP2721854B2 (ja) * 1984-12-21 1998-03-04 大塚製薬株式会社 抗腫瘍活性物質
JP2583753B2 (ja) * 1984-12-21 1997-02-19 大塚製薬株式会社 抗腫瘍活性物質およびその製造法
EP0199574B1 (en) * 1985-04-22 1991-10-23 Genentech, Inc. Human tissue plasminogen activator mutants, methods and intermediates therefor, and compositions using such mutants
US4818698A (en) * 1985-08-23 1989-04-04 Toyo Jozo Co., Ltd. Polypeptides and preparation process thereof
NZ226543A (en) * 1987-10-22 1992-02-25 Merck & Co Inc Recombinant mutant acidic fibroblast growth factor
ES2085329T3 (es) * 1989-02-17 1996-06-01 Merck & Co Inc Agente anticanceroso proteico.
IL93723A (en) * 1989-03-22 1997-02-18 Merck & Co Inc Cystein modified truncated pseudomonas exotoxin A
US6207798B1 (en) 1989-08-03 2001-03-27 Merck & Co., Inc. Modified PE40 toxin fusion proteins
JPH0751621A (ja) * 1993-08-12 1995-02-28 Kansei Kogyo Kk 静電吸着による管内面更生工法
AR034749A1 (es) * 2001-07-09 2004-03-17 Schering Ag Formulaciones de interferon beta humano
US20050008616A1 (en) * 2003-07-11 2005-01-13 Schering Aktiengesellschaft Recombinant human interferon-beta-1b polypeptides
CN116075523A (zh) * 2020-04-29 2023-05-05 基因制药株式会社 具有融合的干扰素-β突变蛋白和抗体的重组蛋白以及包含其的药物组合物

Also Published As

Publication number Publication date
JPH0380475B2 (enrdf_load_stackoverflow) 1991-12-25
JPS5993093A (ja) 1984-05-29
IL90047A (en) 1992-12-01
ZA837789B (en) 1984-11-28
JPS6128384A (ja) 1986-02-08
JPS6357440B2 (enrdf_load_stackoverflow) 1988-11-11
JPS6128393A (ja) 1986-02-08
IN161992B (enrdf_load_stackoverflow) 1988-03-12
JPS6128394A (ja) 1986-02-08

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