JPH0576954B2 - - Google Patents

Info

Publication number
JPH0576954B2
JPH0576954B2 JP8644903A JP4490386A JPH0576954B2 JP H0576954 B2 JPH0576954 B2 JP H0576954B2 JP 8644903 A JP8644903 A JP 8644903A JP 4490386 A JP4490386 A JP 4490386A JP H0576954 B2 JPH0576954 B2 JP H0576954B2
Authority
JP
Japan
Prior art keywords
platinum
complex
group
fatty acid
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP8644903A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6296A (ja
Inventor
Michikazu Maeda
Takuma Sasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12675703&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH0576954(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Publication of JPS6296A publication Critical patent/JPS6296A/ja
Publication of JPH0576954B2 publication Critical patent/JPH0576954B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP61044903A 1985-03-06 1986-02-28 脂溶性白金(2)錯体 Granted JPS6296A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP60-43869 1985-03-06
JP4386985 1985-03-06

Publications (2)

Publication Number Publication Date
JPS6296A JPS6296A (ja) 1987-01-06
JPH0576954B2 true JPH0576954B2 (enExample) 1993-10-25

Family

ID=12675703

Family Applications (1)

Application Number Title Priority Date Filing Date
JP61044903A Granted JPS6296A (ja) 1985-03-06 1986-02-28 脂溶性白金(2)錯体

Country Status (8)

Country Link
US (1) US6613799B1 (enExample)
EP (1) EP0193936B1 (enExample)
JP (1) JPS6296A (enExample)
AT (1) ATE43605T1 (enExample)
AU (1) AU587235B2 (enExample)
CA (1) CA1261864A (enExample)
DE (1) DE3663667D1 (enExample)
ES (1) ES8704505A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5384127A (en) * 1985-10-18 1995-01-24 Board Of Regents, The University Of Texas System Stable liposomal formulations of lipophilic platinum compounds
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5117022A (en) * 1985-10-18 1992-05-26 The Board Of Regents, The University Of Texas System Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
GB8620917D0 (en) * 1986-08-29 1986-10-08 Davidson B C Platinum derivatives & cancer treatments
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
US4880832A (en) * 1987-03-06 1989-11-14 Sumitomo Pharmaceuticals Company, Ltd. Liposoluble platinum (II) complex and preparation thereof
AU592927B2 (en) * 1988-02-18 1990-01-25 Sumitomo Pharmaceuticals Company, Limited Liposoluble platinum (ii) complex and preparation thereof
CA1339034C (en) * 1988-08-22 1997-04-01 Paul A. Tremblay Platinum complexes of single isomer neoalkyl acids
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
US5434256A (en) * 1988-11-22 1995-07-18 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
ES2097085B1 (es) * 1994-06-30 1997-11-16 Univ Salamanca Nuevos complejos de coordinacion de metales de transicion con actividad citostatica.
US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
US6426367B1 (en) * 1999-09-09 2002-07-30 Efa Sciences Llc Methods for selectively occluding blood supplies to neoplasias
JP5096657B2 (ja) 2000-08-11 2012-12-12 大日本住友製薬株式会社 シスプラチン耐性癌治療剤
AUPR644301A0 (en) * 2001-07-17 2001-08-09 Unisearch Limited Method and composition for treatment of cancer
WO2005023824A2 (en) * 2003-08-13 2005-03-17 University Of South Florida Methods for inhibiting tumor cell proliferation
ITMI20052449A1 (it) * 2005-12-22 2007-06-23 Cell Therapeutics Europe Srl Nuovi bis-platino complessi ad attivita' antitumorale
CN101402655B (zh) * 2008-11-07 2011-06-15 江苏奥赛康药业有限公司 一种米铂的制备方法
CN101830933B (zh) * 2010-05-28 2012-07-25 昆明贵研药业有限公司 一种合成抗肿瘤药物米铂的方法
CN101899067A (zh) * 2010-08-10 2010-12-01 东南大学 米铂的制备方法
CN102516311B (zh) * 2011-11-03 2014-05-28 南京优科生物医药有限公司 一种米铂的制备方法
CN103570766B (zh) * 2012-08-09 2016-04-13 浙江海昶生物医药技术有限公司 一种新型铂类脂质体制剂及其制备方法
JP2016531112A (ja) * 2013-07-25 2016-10-06 ネムコア メディカル イノベーションズ インコーポレイテッド 疎水性白金誘導体のナノエマルジョン
CN103910762A (zh) * 2014-04-16 2014-07-09 北京美迪康信医药科技有限公司 一种米铂的制备方法
WO2015166498A1 (en) * 2014-05-02 2015-11-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Pt (iv) derivatives and nanocarriers comprising them
CN104211734A (zh) * 2014-08-10 2014-12-17 昆明贵研药业有限公司 一种合成抗肿瘤药物庚铂的新方法
CN105153238B (zh) * 2015-09-12 2017-08-15 山东罗欣药业集团股份有限公司 一种米铂的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR898614A (fr) 1942-10-15 1945-04-27 Auergesellschaft Ag Verre à lunettes contenant du néodyme
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
SE447385B (sv) * 1977-10-19 1986-11-10 Johnson Matthey Co Ltd Cis-koordinationsforeningar av platina
SE447902B (sv) * 1977-10-19 1986-12-22 Johnson Matthey Co Ltd Cis-koordinationsforening av platina och komposition innehallande foreningen
US4203912A (en) * 1977-10-19 1980-05-20 Johnson, Matthey & Co., Limited Compositions containing platinum
US4284579A (en) * 1979-07-17 1981-08-18 The United States Of America As Represented By The Of The Department Of Health & Human Services (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex
JPS5716895A (en) * 1980-07-05 1982-01-28 Otsuka Chem Co Ltd Platinum 2 complex and antitumor agent containing the same as active principle
JPS57123198A (en) * 1981-01-23 1982-07-31 Shionogi & Co Ltd Novel platinum complex
EP0113508A1 (en) 1982-11-04 1984-07-18 Inco Research & Development Center, Inc. Hydrophobic platinum compounds and their preparation
EP0130482B1 (en) * 1983-06-20 1988-12-28 Research Corporation Diaminocyclohexane platinum complexes, process for preparing same and pharmaceutical compositions containing same
EP0136012B1 (en) 1983-08-05 1989-04-19 Yoshinori Kidani Cytostatic platinum complexes
US5041581A (en) 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes

Also Published As

Publication number Publication date
US6613799B1 (en) 2003-09-02
AU587235B2 (en) 1989-08-10
EP0193936A1 (en) 1986-09-10
JPS6296A (ja) 1987-01-06
ATE43605T1 (de) 1989-06-15
ES8704505A1 (es) 1987-04-01
EP0193936B1 (en) 1989-05-31
AU5435886A (en) 1986-09-11
ES552722A0 (es) 1987-04-01
CA1261864A (en) 1989-09-26
DE3663667D1 (en) 1989-07-06

Similar Documents

Publication Publication Date Title
JPH0576954B2 (enExample)
US8247445B2 (en) Platinum complexes and methods of use
US5194645A (en) Trans-pt (iv) compounds
JP5385923B2 (ja) N−複素環式カルベン白金誘導体、この調製、およびこの治療用途
JPS6326116B2 (enExample)
HU184922B (en) Process for preparing platinum/iv./-diamine complexes and pharma ceutical compositions containing thereof
US5275827A (en) Cis-platinum complexes with chelating amines and sulphinyl carboxylates
US20050090478A1 (en) Platinum complexes and their use in cancer treatment
HU188035B (en) Process for producing new plantinum-diamine complex
TWI233929B (en) Novel, water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases
US4880832A (en) Liposoluble platinum (II) complex and preparation thereof
US5132323A (en) 1,2-diaminocyclohexane-platinum complexes with antitumor activity
US4739087A (en) Antineoplastic platinum complexes
US7977500B2 (en) Platinum complexes for targeted drug delivery
US4831170A (en) Pharmaceutically active phospino-hydrocarbon-group VIII-metal complexes, antitumor compositions containing these complexes, and a process for preparing said compounds or antitumor compositions
FI83086C (fi) Foerfarande foer framstaellning av komplex med tumormotverkande effekt.
TW302364B (enExample)
US8703756B2 (en) Synthetic procedure and cancer treatment with cisplatin derivatives
JP2005511497A (ja) 光反応性化合物および組成物
GB2147578A (en) Novel organic platinum complex and process for the preparation thereof
KR840000800B1 (ko) 백금 디아민 착염의 제조방법
Kay Platinum complexes for targeted drug delivery
JPH0827174A (ja) 抗腫瘍性シクロヘキサンジアミン誘導体白金(iv)錯体
JPH01163190A (ja) 新規白金(2)錯体および悪性腫瘍治療剤
JPWO1989004319A1 (ja) 新規白金(2)錯体、その製造および悪性腫瘍治療剤

Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees