ATE43605T1 - Lipoloeslicher platin(ii)-komplex und dessen herstellung. - Google Patents

Lipoloeslicher platin(ii)-komplex und dessen herstellung.

Info

Publication number
ATE43605T1
ATE43605T1 AT86102860T AT86102860T ATE43605T1 AT E43605 T1 ATE43605 T1 AT E43605T1 AT 86102860 T AT86102860 T AT 86102860T AT 86102860 T AT86102860 T AT 86102860T AT E43605 T1 ATE43605 T1 AT E43605T1
Authority
AT
Austria
Prior art keywords
platinum
derivatives
complex
fatty acid
ammine
Prior art date
Application number
AT86102860T
Other languages
English (en)
Inventor
Mitsuaki Maeda
Takuma Sasaki
Original Assignee
Sumitomo Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12675703&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE43605(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sumitomo Pharma filed Critical Sumitomo Pharma
Application granted granted Critical
Publication of ATE43605T1 publication Critical patent/ATE43605T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT86102860T 1985-03-06 1986-03-05 Lipoloeslicher platin(ii)-komplex und dessen herstellung. ATE43605T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4386985 1985-03-06
EP86102860A EP0193936B1 (de) 1985-03-06 1986-03-05 Lipolöslicher Platin(II)-Komplex und dessen Herstellung

Publications (1)

Publication Number Publication Date
ATE43605T1 true ATE43605T1 (de) 1989-06-15

Family

ID=12675703

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86102860T ATE43605T1 (de) 1985-03-06 1986-03-05 Lipoloeslicher platin(ii)-komplex und dessen herstellung.

Country Status (8)

Country Link
US (1) US6613799B1 (de)
EP (1) EP0193936B1 (de)
JP (1) JPS6296A (de)
AT (1) ATE43605T1 (de)
AU (1) AU587235B2 (de)
CA (1) CA1261864A (de)
DE (1) DE3663667D1 (de)
ES (1) ES8704505A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5384127A (en) * 1985-10-18 1995-01-24 Board Of Regents, The University Of Texas System Stable liposomal formulations of lipophilic platinum compounds
US5117022A (en) * 1985-10-18 1992-05-26 The Board Of Regents, The University Of Texas System Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
GB8620917D0 (en) * 1986-08-29 1986-10-08 Davidson B C Platinum derivatives & cancer treatments
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
CA1283904C (en) * 1987-03-06 1991-05-07 Mitsuaki Maeda Liposoluble platinum (ii) complex and preparation thereof
AU592927B2 (en) * 1988-02-18 1990-01-25 Sumitomo Pharmaceuticals Company, Limited Liposoluble platinum (ii) complex and preparation thereof
CA1339034C (en) * 1988-08-22 1997-04-01 Paul A. Tremblay Platinum complexes of single isomer neoalkyl acids
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5434256A (en) * 1988-11-22 1995-07-18 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
ES2097085B1 (es) * 1994-06-30 1997-11-16 Univ Salamanca Nuevos complejos de coordinacion de metales de transicion con actividad citostatica.
US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
US6426367B1 (en) * 1999-09-09 2002-07-30 Efa Sciences Llc Methods for selectively occluding blood supplies to neoplasias
EP1319403A4 (de) 2000-08-11 2009-07-08 Dainippon Sumitomo Pharma Co Mittel gegen cisplatin-toleranten krebs
AUPR644301A0 (en) * 2001-07-17 2001-08-09 Unisearch Limited Method and composition for treatment of cancer
CA2535584A1 (en) * 2003-08-13 2005-02-24 University Of South Florida Platinum complexes for the treatment of tumors
ITMI20052449A1 (it) * 2005-12-22 2007-06-23 Cell Therapeutics Europe Srl Nuovi bis-platino complessi ad attivita' antitumorale
CN101402655B (zh) * 2008-11-07 2011-06-15 江苏奥赛康药业有限公司 一种米铂的制备方法
CN101830933B (zh) * 2010-05-28 2012-07-25 昆明贵研药业有限公司 一种合成抗肿瘤药物米铂的方法
CN101899067A (zh) * 2010-08-10 2010-12-01 东南大学 米铂的制备方法
CN102516311B (zh) * 2011-11-03 2014-05-28 南京优科生物医药有限公司 一种米铂的制备方法
CN103570766B (zh) * 2012-08-09 2016-04-13 浙江海昶生物医药技术有限公司 一种新型铂类脂质体制剂及其制备方法
EP3024441A4 (de) * 2013-07-25 2017-04-19 Nemucore Medical Innovations, Inc. Nanoemulsionen aus einem hydrophoben platinderivat
CN103910762A (zh) * 2014-04-16 2014-07-09 北京美迪康信医药科技有限公司 一种米铂的制备方法
PL3137473T3 (pl) * 2014-05-02 2020-06-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Pochodne Pt (iv) i zawierające je nanonośniki
CN104211734A (zh) * 2014-08-10 2014-12-17 昆明贵研药业有限公司 一种合成抗肿瘤药物庚铂的新方法
CN105153238B (zh) * 2015-09-12 2017-08-15 山东罗欣药业集团股份有限公司 一种米铂的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR898614A (fr) 1942-10-15 1945-04-27 Auergesellschaft Ag Verre à lunettes contenant du néodyme
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
SE447385B (sv) * 1977-10-19 1986-11-10 Johnson Matthey Co Ltd Cis-koordinationsforeningar av platina
US4225529A (en) * 1977-10-19 1980-09-30 Johnson, Matthey & Co., Limited Compositions containing platinum
US4203912A (en) * 1977-10-19 1980-05-20 Johnson, Matthey & Co., Limited Compositions containing platinum
US4284579A (en) * 1979-07-17 1981-08-18 The United States Of America As Represented By The Of The Department Of Health & Human Services (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex
JPS5716895A (en) * 1980-07-05 1982-01-28 Otsuka Chem Co Ltd Platinum 2 complex and antitumor agent containing the same as active principle
JPS57123198A (en) * 1981-01-23 1982-07-31 Shionogi & Co Ltd Novel platinum complex
EP0113508A1 (de) 1982-11-04 1984-07-18 Inco Research & Development Center, Inc. Hydrophobische Platinverbindungen und ihre Herstellung
JPS6013795A (ja) * 1983-06-20 1985-01-24 リサ−チ・コ−ポレイシヨン ジアミノシクロヘキサン白金錯体
US4710577A (en) 1983-08-05 1987-12-01 Yoshinori Kidani Cytostatic platinum organic complexes
US5041581A (en) 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes

Also Published As

Publication number Publication date
AU587235B2 (en) 1989-08-10
AU5435886A (en) 1986-09-11
JPH0576954B2 (de) 1993-10-25
EP0193936A1 (de) 1986-09-10
CA1261864A (en) 1989-09-26
ES8704505A1 (es) 1987-04-01
DE3663667D1 (en) 1989-07-06
US6613799B1 (en) 2003-09-02
ES552722A0 (es) 1987-04-01
EP0193936B1 (de) 1989-05-31
JPS6296A (ja) 1987-01-06

Similar Documents

Publication Publication Date Title
ATE43605T1 (de) Lipoloeslicher platin(ii)-komplex und dessen herstellung.
ATE168373T1 (de) Benzofuranyl- und thiophenylalkancarbonsäurederivate
DE3863857D1 (de) Arylthioalkylphenylcarbonsaeuren, diese enthaltende zusammensetzungen und deren verwendung.
DE68911742D1 (de) Substituierte flavonoide Verbindungen, ihre Salze, ihre Herstellung und die enthaltende Arnzeizusammensetzungen.
EP0194161A3 (en) Cyclopentaûd¨pyrimidine derivatives, their preparation and use
MXPA04007068A (es) Derivados de almidon, conjugados de almidon con sustancia activa, metodo para su produccion y su uso como medicamentos.
ATE38991T1 (de) In 2-stellung substituierte 1,3propyledendephosphonat-derivate, ihre herstellung und pharmazeutische zusammensetzungen, die sie enthalten.
DE3882895D1 (de) Imid-derivate, ihre herstellung und verwendung.
DE3877386D1 (de) Antikrebsverbindungen.
GB1386150A (en) 6-acylaminophenyl-4,5-dihydropyridazones
EP0281463A3 (de) Platin-Komplex, Verfahren zu dessen Herstellung und pharamzuetische Zusammensetzung, die diesen Komplex enthält
DE2965701D1 (en) 1-imidazol-2-ylidene-3-thienyl-urea derivatives, processes therefor, and pharmaceutical compositions
ATE61360T1 (de) Antioxidierend wirkende verbindungen, ihre herstellung und ihre verwendung.
GB1394619A (en) Imides
ATE64740T1 (de) Platin enthaltender cytostatischer wirkstoff.
GB1082444A (en) Novel benzdiaz[1,4]epine derivatives and a process for the manufacture thereof
ATE88176T1 (de) 2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung.
ATE61590T1 (de) Rhizoxinderivate, ihre herstellung und pharmazeutische verwendung.
EP0299076A4 (en) 5-hydroxyindole-3-carboxamide compound and medicinal use thereof
DE69511449D1 (de) Octahydro-2-Naphthalincarbonsäure-Derivate, ihre Herstellung und Verwendung
JPS6466138A (en) (6)-gingerol derivative
DE3887612D1 (de) Salicylate, ihre Salze, diese enthaltende pharmazeutische Kompositionen und ihr Herstellungsverfahren.
DE1668887C3 (de) Ca-SaIz der 1,2 -Dithia-cyclopentan - 3- valerian Säure (Thioctsäure)
JPS646290A (en) Fat-soluble platinum ii complex and production thereof
DE3679257D1 (de) 4-cyanopiperidine-derivate, herstellung und anwendung.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee