DE3663667D1 - Liposoluble platinum (ii) complex and preparation thereof - Google Patents

Liposoluble platinum (ii) complex and preparation thereof

Info

Publication number
DE3663667D1
DE3663667D1 DE8686102860T DE3663667T DE3663667D1 DE 3663667 D1 DE3663667 D1 DE 3663667D1 DE 8686102860 T DE8686102860 T DE 8686102860T DE 3663667 T DE3663667 T DE 3663667T DE 3663667 D1 DE3663667 D1 DE 3663667D1
Authority
DE
Germany
Prior art keywords
derivatives
platinum
complex
fatty acid
ammine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8686102860T
Other languages
German (de)
English (en)
Inventor
Mitsuaki Maeda
Takuma Sasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12675703&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3663667(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Application granted granted Critical
Publication of DE3663667D1 publication Critical patent/DE3663667D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8686102860T 1985-03-06 1986-03-05 Liposoluble platinum (ii) complex and preparation thereof Expired DE3663667D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4386985 1985-03-06

Publications (1)

Publication Number Publication Date
DE3663667D1 true DE3663667D1 (en) 1989-07-06

Family

ID=12675703

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686102860T Expired DE3663667D1 (en) 1985-03-06 1986-03-05 Liposoluble platinum (ii) complex and preparation thereof

Country Status (8)

Country Link
US (1) US6613799B1 (enExample)
EP (1) EP0193936B1 (enExample)
JP (1) JPS6296A (enExample)
AT (1) ATE43605T1 (enExample)
AU (1) AU587235B2 (enExample)
CA (1) CA1261864A (enExample)
DE (1) DE3663667D1 (enExample)
ES (1) ES8704505A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5384127A (en) * 1985-10-18 1995-01-24 Board Of Regents, The University Of Texas System Stable liposomal formulations of lipophilic platinum compounds
US5117022A (en) * 1985-10-18 1992-05-26 The Board Of Regents, The University Of Texas System Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
GB8620917D0 (en) * 1986-08-29 1986-10-08 Davidson B C Platinum derivatives & cancer treatments
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
CA1283904C (en) * 1987-03-06 1991-05-07 Mitsuaki Maeda Liposoluble platinum (ii) complex and preparation thereof
AU592927B2 (en) * 1988-02-18 1990-01-25 Sumitomo Pharmaceuticals Company, Limited Liposoluble platinum (ii) complex and preparation thereof
CA1339034C (en) * 1988-08-22 1997-04-01 Paul A. Tremblay Platinum complexes of single isomer neoalkyl acids
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
US5434256A (en) * 1988-11-22 1995-07-18 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
ES2097085B1 (es) * 1994-06-30 1997-11-16 Univ Salamanca Nuevos complejos de coordinacion de metales de transicion con actividad citostatica.
US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
US6426367B1 (en) * 1999-09-09 2002-07-30 Efa Sciences Llc Methods for selectively occluding blood supplies to neoplasias
WO2002013817A1 (en) * 2000-08-11 2002-02-21 Sumitomo Pharmaceuticals Co., Ltd. Remedies for cisplatin-tolerant cancer
AUPR644301A0 (en) * 2001-07-17 2001-08-09 Unisearch Limited Method and composition for treatment of cancer
DE602004015811D1 (de) * 2003-08-13 2008-09-25 Univ South Florida Verfahren zur inhibierung der proliferation von tumorzellen, bei dem platinkomplexe eingesetzt werden
ITMI20052449A1 (it) 2005-12-22 2007-06-23 Cell Therapeutics Europe Srl Nuovi bis-platino complessi ad attivita' antitumorale
CN101402655B (zh) * 2008-11-07 2011-06-15 江苏奥赛康药业有限公司 一种米铂的制备方法
CN101830933B (zh) * 2010-05-28 2012-07-25 昆明贵研药业有限公司 一种合成抗肿瘤药物米铂的方法
CN101899067A (zh) * 2010-08-10 2010-12-01 东南大学 米铂的制备方法
CN102516311B (zh) * 2011-11-03 2014-05-28 南京优科生物医药有限公司 一种米铂的制备方法
CN103570766B (zh) * 2012-08-09 2016-04-13 浙江海昶生物医药技术有限公司 一种新型铂类脂质体制剂及其制备方法
JP2016531112A (ja) * 2013-07-25 2016-10-06 ネムコア メディカル イノベーションズ インコーポレイテッド 疎水性白金誘導体のナノエマルジョン
CN103910762A (zh) * 2014-04-16 2014-07-09 北京美迪康信医药科技有限公司 一种米铂的制备方法
ES2774662T3 (es) * 2014-05-02 2020-07-22 Yissum Research Development Company Of The Herbrew Univ Of Jerusalem Ltd Derivados de Pt (IV) y nanotransportadores que los comprenden
CN104211734A (zh) * 2014-08-10 2014-12-17 昆明贵研药业有限公司 一种合成抗肿瘤药物庚铂的新方法
CN105153238B (zh) * 2015-09-12 2017-08-15 山东罗欣药业集团股份有限公司 一种米铂的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR898614A (fr) 1942-10-15 1945-04-27 Auergesellschaft Ag Verre à lunettes contenant du néodyme
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
US4203912A (en) * 1977-10-19 1980-05-20 Johnson, Matthey & Co., Limited Compositions containing platinum
US4225529A (en) * 1977-10-19 1980-09-30 Johnson, Matthey & Co., Limited Compositions containing platinum
SE447385B (sv) * 1977-10-19 1986-11-10 Johnson Matthey Co Ltd Cis-koordinationsforeningar av platina
US4284579A (en) * 1979-07-17 1981-08-18 The United States Of America As Represented By The Of The Department Of Health & Human Services (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex
JPS5716895A (en) * 1980-07-05 1982-01-28 Otsuka Chem Co Ltd Platinum 2 complex and antitumor agent containing the same as active principle
JPS57123198A (en) * 1981-01-23 1982-07-31 Shionogi & Co Ltd Novel platinum complex
EP0113508A1 (en) * 1982-11-04 1984-07-18 Inco Research & Development Center, Inc. Hydrophobic platinum compounds and their preparation
DE3475782D1 (en) * 1983-06-20 1989-02-02 Research Corp Diaminocyclohexane platinum complexes, process for preparing same and pharmaceutical compositions containing same
DE3477788D1 (en) 1983-08-05 1989-05-24 Yoshinori Kidani Cytostatic platinum complexes
US5041581A (en) 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes

Also Published As

Publication number Publication date
ATE43605T1 (de) 1989-06-15
JPS6296A (ja) 1987-01-06
JPH0576954B2 (enExample) 1993-10-25
CA1261864A (en) 1989-09-26
AU5435886A (en) 1986-09-11
EP0193936B1 (en) 1989-05-31
ES552722A0 (es) 1987-04-01
US6613799B1 (en) 2003-09-02
ES8704505A1 (es) 1987-04-01
AU587235B2 (en) 1989-08-10
EP0193936A1 (en) 1986-09-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee