JPH0564062B2 - - Google Patents
Info
- Publication number
- JPH0564062B2 JPH0564062B2 JP61198983A JP19898386A JPH0564062B2 JP H0564062 B2 JPH0564062 B2 JP H0564062B2 JP 61198983 A JP61198983 A JP 61198983A JP 19898386 A JP19898386 A JP 19898386A JP H0564062 B2 JPH0564062 B2 JP H0564062B2
- Authority
- JP
- Japan
- Prior art keywords
- leg
- laminated
- rubber stopper
- rubber
- container
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229920001971 elastomer Polymers 0.000 claims description 88
- 239000005060 rubber Substances 0.000 claims description 88
- 229920005989 resin Polymers 0.000 claims description 24
- 239000011347 resin Substances 0.000 claims description 24
- 239000003814 drug Substances 0.000 claims description 22
- 230000002093 peripheral effect Effects 0.000 claims description 7
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims description 6
- 229910052731 fluorine Inorganic materials 0.000 claims description 6
- 239000011737 fluorine Substances 0.000 claims description 6
- 150000002221 fluorine Chemical class 0.000 claims description 3
- 238000000034 method Methods 0.000 description 17
- 230000000694 effects Effects 0.000 description 10
- 238000004519 manufacturing process Methods 0.000 description 9
- 229940079593 drug Drugs 0.000 description 8
- 238000001035 drying Methods 0.000 description 6
- 238000001704 evaporation Methods 0.000 description 5
- 230000008020 evaporation Effects 0.000 description 5
- 208000012266 Needlestick injury Diseases 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000000465 moulding Methods 0.000 description 4
- 238000001291 vacuum drying Methods 0.000 description 4
- 238000004073 vulcanization Methods 0.000 description 4
- 229910052782 aluminium Inorganic materials 0.000 description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 229920005549 butyl rubber Polymers 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 229920001038 ethylene copolymer Polymers 0.000 description 2
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 229940127557 pharmaceutical product Drugs 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000009777 vacuum freeze-drying Methods 0.000 description 2
- BQCIDUSAKPWEOX-UHFFFAOYSA-N 1,1-Difluoroethene Chemical compound FC(F)=C BQCIDUSAKPWEOX-UHFFFAOYSA-N 0.000 description 1
- JGZXFYJBOHKPTL-UHFFFAOYSA-N C=C.C=C.F.F.F.Cl Chemical group C=C.C=C.F.F.F.Cl JGZXFYJBOHKPTL-UHFFFAOYSA-N 0.000 description 1
- WQNTXSXCXGWOBT-UHFFFAOYSA-N C=C.C=C.F.F.F.F Chemical group C=C.C=C.F.F.F.F WQNTXSXCXGWOBT-UHFFFAOYSA-N 0.000 description 1
- XPEZVQDSLVQKOT-UHFFFAOYSA-N CC=C.C=C.F.F.F.F.F.F.F.F.F.F Chemical compound CC=C.C=C.F.F.F.F.F.F.F.F.F.F XPEZVQDSLVQKOT-UHFFFAOYSA-N 0.000 description 1
- 229930186147 Cephalosporin Natural products 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 239000005062 Polybutadiene Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 229940124587 cephalosporin Drugs 0.000 description 1
- 150000001780 cephalosporins Chemical class 0.000 description 1
- 229920006026 co-polymeric resin Polymers 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000013583 drug formulation Substances 0.000 description 1
- HQQADJVZYDDRJT-UHFFFAOYSA-N ethene;prop-1-ene Chemical group C=C.CC=C HQQADJVZYDDRJT-UHFFFAOYSA-N 0.000 description 1
- 229920000840 ethylene tetrafluoroethylene copolymer Polymers 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- XUCNUKMRBVNAPB-UHFFFAOYSA-N fluoroethene Chemical compound FC=C XUCNUKMRBVNAPB-UHFFFAOYSA-N 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 229920005555 halobutyl Polymers 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 229920003049 isoprene rubber Polymers 0.000 description 1
- 238000003475 lamination Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229920002857 polybutadiene Polymers 0.000 description 1
- 230000000379 polymerizing effect Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000000935 solvent evaporation Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- 229920001897 terpolymer Polymers 0.000 description 1
- BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical group FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 description 1
- 239000004636 vulcanized rubber Substances 0.000 description 1
Landscapes
- Closures For Containers (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Casting Or Compression Moulding Of Plastics Or The Like (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61198983A JPS62176450A (ja) | 1986-08-27 | 1986-08-27 | 医薬用積層ゴム栓 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61198983A JPS62176450A (ja) | 1986-08-27 | 1986-08-27 | 医薬用積層ゴム栓 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62176450A JPS62176450A (ja) | 1987-08-03 |
| JPH0564062B2 true JPH0564062B2 (enrdf_load_stackoverflow) | 1993-09-13 |
Family
ID=16400163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61198983A Granted JPS62176450A (ja) | 1986-08-27 | 1986-08-27 | 医薬用積層ゴム栓 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS62176450A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005350095A (ja) * | 2004-06-09 | 2005-12-22 | Natl Inst Of Radiological Sciences | 気密蓋 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02114056U (enrdf_load_stackoverflow) * | 1989-02-28 | 1990-09-12 | ||
| JPH0620764B2 (ja) * | 1989-10-23 | 1994-03-23 | 株式会社ニッショー | バイアル用ゴム栓の製造方法 |
| JP2008183556A (ja) * | 1996-11-08 | 2008-08-14 | Moritex Corp | 反応管のシール構造 |
| JP4316706B2 (ja) * | 1998-12-16 | 2009-08-19 | 日本クラウンコルク株式会社 | 加熱殺菌乃至滅菌方法 |
| US6566144B1 (en) * | 2000-03-27 | 2003-05-20 | Atrix Laboratories | Cover plate for use in lyophilization |
| JP3530832B2 (ja) * | 2001-05-11 | 2004-05-24 | 住友ゴム工業株式会社 | 医療用ゴム栓 |
| JP2004216753A (ja) * | 2003-01-16 | 2004-08-05 | Sumitomo Rubber Ind Ltd | 医薬用ゴム栓の製造方法 |
| KR102291620B1 (ko) * | 2021-03-11 | 2021-08-20 | 주식회사 다산씨엔텍 | 용기용 캡 |
-
1986
- 1986-08-27 JP JP61198983A patent/JPS62176450A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005350095A (ja) * | 2004-06-09 | 2005-12-22 | Natl Inst Of Radiological Sciences | 気密蓋 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS62176450A (ja) | 1987-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| EXPY | Cancellation because of completion of term |