JPH0559710B2 - - Google Patents
Info
- Publication number
- JPH0559710B2 JPH0559710B2 JP60037168A JP3716885A JPH0559710B2 JP H0559710 B2 JPH0559710 B2 JP H0559710B2 JP 60037168 A JP60037168 A JP 60037168A JP 3716885 A JP3716885 A JP 3716885A JP H0559710 B2 JPH0559710 B2 JP H0559710B2
- Authority
- JP
- Japan
- Prior art keywords
- dna
- plasmid
- gene
- strain
- threonine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- JGGLZQUGOKVDGS-VYTIMWRQSA-N aspartate semialdehyde Chemical compound O[C@@H]1[C@@H](NC(=O)C)CO[C@H](CO)[C@H]1O[C@@H]1[C@@H](NC(C)=O)[C@H](O)[C@H](O[C@@H]2[C@H]([C@@H](O[C@@H]3[C@@H]([C@H](O)[C@@H](O)[C@H](CO)O3)O[C@@H]3[C@@H]([C@H](O)[C@@H](O)[C@H](CO)O3)O[C@@H]3[C@H]([C@H](O)[C@@H](O)[C@H](CO)O3)O)[C@@H](O)[C@H](CO[C@@H]3[C@H]([C@H](O[C@@H]4[C@H]([C@H](O)[C@@H](O)[C@H](CO)O4)O)[C@@H](O)[C@H](CO)O3)O)O2)O)[C@H](CO)O1 JGGLZQUGOKVDGS-VYTIMWRQSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- ZAYJDMWJYCTABM-UHFFFAOYSA-N beta-hydroxy leucine Natural products CC(C)C(O)C(N)C(O)=O ZAYJDMWJYCTABM-UHFFFAOYSA-N 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 241000186254 coryneform bacterium Species 0.000 description 1
- 238000012136 culture method Methods 0.000 description 1
- 239000012228 culture supernatant Substances 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- 238000012869 ethanol precipitation Methods 0.000 description 1
- 239000013613 expression plasmid Substances 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 229910001410 inorganic ion Inorganic materials 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 description 1
- 229910000357 manganese(II) sulfate Inorganic materials 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 239000011785 micronutrient Substances 0.000 description 1
- 235000013369 micronutrients Nutrition 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 235000013379 molasses Nutrition 0.000 description 1
- 229940056360 penicillin g Drugs 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229940074404 sodium succinate Drugs 0.000 description 1
- ZDQYSKICYIVCPN-UHFFFAOYSA-L sodium succinate (anhydrous) Chemical compound [Na+].[Na+].[O-]C(=O)CCC([O-])=O ZDQYSKICYIVCPN-UHFFFAOYSA-L 0.000 description 1
- 229940001941 soy protein Drugs 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- WPLOVIFNBMNBPD-ATHMIXSHSA-N subtilin Chemical compound CC1SCC(NC2=O)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(=C)C(=O)NC(CCCCN)C(O)=O)CSC(C)C2NC(=O)C(CC(C)C)NC(=O)C1NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1NC(=O)C(=C/C)/NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2NC(=O)CNC(=O)C3CCCN3C(=O)C(NC(=O)C3NC(=O)C(CC(C)C)NC(=O)C(=C)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)CC=4C5=CC=CC=C5NC=4)CSC3)C(C)SC2)C(C)C)C(C)SC1)CC1=CC=CC=C1 WPLOVIFNBMNBPD-ATHMIXSHSA-N 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Description
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Claims (1)
- ïŒ ãã¬ããã¯ããªãŠã å±çŽ°èç±æ¥ã®ãã¢ã»ãªã³
ãããŒãŒãã³ãŒãããéºäŒåãçµèŸŒãŸããŠãã第
ïŒã®ãã©ã¹ããåã³ãã¬ããã¯ããªãŠã å±çŽ°èç±
æ¥ã®ãã¢ã»ãªã³ããããã²ããŒãŒãã³ãŒãããéº
äŒåãçµèŸŒãŸããŠãã第ïŒã®ãã©ã¹ãããæãã
ã³ãªããã«ã 现èãå¹é€ããããšãç¹åŸŽãšããã¹
ã¬ãªãã³åã¯ã€ãœãã€ã·ã³ã®è£œé æ³ã
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3716885A JPS61195695A (ja) | 1985-02-26 | 1985-02-26 | ã¹ã¬ãªãã³åã¯ã€ãœãã€ã·ã³ã®è£œé æ³ |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3716885A JPS61195695A (ja) | 1985-02-26 | 1985-02-26 | ã¹ã¬ãªãã³åã¯ã€ãœãã€ã·ã³ã®è£œé æ³ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61195695A JPS61195695A (ja) | 1986-08-29 |
| JPH0559710B2 true JPH0559710B2 (ja) | 1993-08-31 |
Family
ID=12490068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3716885A Granted JPS61195695A (ja) | 1985-02-26 | 1985-02-26 | ã¹ã¬ãªãã³åã¯ã€ãœãã€ã·ã³ã®è£œé æ³ |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS61195695A (ja) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3966583B2 (ja) * | 1997-06-23 | 2007-08-29 | ååéé µå·¥æ¥æ ªåŒäŒç€Ÿ | çºé µæ³ã«ããïœâã¢ããé žã®è£œé æ³ |
| CA2319283A1 (en) | 1999-09-20 | 2001-03-20 | Kuniki Kino | Method for producing l-amino acids by fermentation |
| JP4245746B2 (ja) | 1999-09-20 | 2009-04-02 | ååçºé µãã€ãªæ ªåŒäŒç€Ÿ | çºé µæ³ã«ããã¢ããé žã®è£œé æ³ |
| JP2009153382A (ja) | 2006-03-30 | 2009-07-16 | Ajinomoto Co Inc | ã¡ã¿ããŒã«è³åæ§çŽ°èãçšããã«ã«ãã³é žã®è£œé æ³ |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57186496A (en) * | 1981-05-11 | 1982-11-16 | Ajinomoto Co Inc | Preparation of l-threonine by fermentation |
| JPS6030693A (ja) * | 1983-07-29 | 1985-02-16 | Kyowa Hakko Kogyo Co Ltd | âã€ãœãã€ã·ã³ã®è£œé æ³ |
-
1985
- 1985-02-26 JP JP3716885A patent/JPS61195695A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57186496A (en) * | 1981-05-11 | 1982-11-16 | Ajinomoto Co Inc | Preparation of l-threonine by fermentation |
| JPS6030693A (ja) * | 1983-07-29 | 1985-02-16 | Kyowa Hakko Kogyo Co Ltd | âã€ãœãã€ã·ã³ã®è£œé æ³ |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS61195695A (ja) | 1986-08-29 |
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| Date | Code | Title | Description |
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| EXPY | Cancellation because of completion of term |