JPH0553378B2 - - Google Patents

Info

Publication number
JPH0553378B2
JPH0553378B2 JP57106294A JP10629482A JPH0553378B2 JP H0553378 B2 JPH0553378 B2 JP H0553378B2 JP 57106294 A JP57106294 A JP 57106294A JP 10629482 A JP10629482 A JP 10629482A JP H0553378 B2 JPH0553378 B2 JP H0553378B2
Authority
JP
Japan
Prior art keywords
vitamin
labeled
monocarboxylic acid
group
item
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP57106294A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58997A (ja
Inventor
Maikuru Hautsu Tomasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Technicon Instruments Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technicon Instruments Corp filed Critical Technicon Instruments Corp
Publication of JPS58997A publication Critical patent/JPS58997A/ja
Publication of JPH0553378B2 publication Critical patent/JPH0553378B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP57106294A 1981-06-22 1982-06-22 ビタミンｂ↓１↓２の検定法およびその検定用のラベル付き誘導体 Granted JPS58997A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8119147 1981-06-22
GB8119147 1981-06-22

Publications (2)

Publication Number Publication Date
JPS58997A JPS58997A (ja) 1983-01-06
JPH0553378B2 true JPH0553378B2 (OSRAM) 1993-08-09

Family

ID=10522711

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57106294A Granted JPS58997A (ja) 1981-06-22 1982-06-22 ビタミンｂ↓１↓２の検定法およびその検定用のラベル付き誘導体

Country Status (5)

Country Link
US (1) US4465775A (OSRAM)
EP (1) EP0069450B1 (OSRAM)
JP (1) JPS58997A (OSRAM)
CA (1) CA1180273A (OSRAM)
DE (1) DE3262956D1 (OSRAM)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8989561B1 (en) 2008-05-29 2015-03-24 Rovi Guides, Inc. Systems and methods for alerting users of the postponed recording of programs
US9021538B2 (en) 1998-07-14 2015-04-28 Rovi Guides, Inc. Client-server based interactive guide with server recording
US9055322B2 (en) 2001-02-21 2015-06-09 Rovi Guides, Inc. Systems and methods for interactive program guides with personal video recording features
US9125169B2 (en) 2011-12-23 2015-09-01 Rovi Guides, Inc. Methods and systems for performing actions based on location-based rules
US9191722B2 (en) 1997-07-21 2015-11-17 Rovi Guides, Inc. System and method for modifying advertisement responsive to EPG information
US9319735B2 (en) 1995-06-07 2016-04-19 Rovi Guides, Inc. Electronic television program guide schedule system and method with data feed access
US9426509B2 (en) 1998-08-21 2016-08-23 Rovi Guides, Inc. Client-server electronic program guide

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ217821A (en) * 1985-10-10 1989-07-27 Biotech Australia Pty Ltd Oral delivery system; complex of active agent and vitamin b12 or analogue thereof
US5807832A (en) * 1987-06-09 1998-09-15 Biotech Australia Pty Limited Oral delivery of biologically active substances bound to vitamin B12
WO1989012826A1 (en) * 1988-06-15 1989-12-28 Beckman Instruments, Inc. Vitamin b12 assay
US4925931A (en) * 1988-07-14 1990-05-15 Mccully Kilmer S N-homocysteine thiolactonyl retinamido cobalamin and methods of use thereof
DE3900648A1 (de) * 1989-01-11 1990-07-12 Boehringer Mannheim Gmbh Neue cobalamin-saeurehydrazide und davon abgeleitete cobalamin-konjugate
WO1990010014A1 (fr) * 1989-02-28 1990-09-07 Teijin Limited Nouveau derive de vitamine b12, sa production et son application
US5405839A (en) * 1989-02-28 1995-04-11 Teijin Limited Vitamin B12 derivative, preparation process thereof, and use thereof
US5506109A (en) * 1989-06-26 1996-04-09 Bayer Corporation Vitamin B12 assay
US5310656A (en) * 1989-06-26 1994-05-10 Tritech Partners Vitamin B12 assay
CA1335707C (en) * 1989-08-15 1995-05-30 Pyare Khanna Drug screening assay
NZ242220A (en) * 1991-04-02 1994-04-27 Biotech Australia Pty Ltd Complex for oral delivery of a substance to the circulatory or lymphatic drainage system comprising microparticle coupled to at least one carrier, the substance being encapsulated by the microparticle
US6942977B1 (en) 1991-04-09 2005-09-13 Bio-Rad Laboratories, Inc. Immunoassays for determining vitamin b12, and reagents and kits therefor
JPH04363659A (ja) * 1991-06-10 1992-12-16 Smithkline Beckman Corp ビタミンｂ１２の分析
JPH10502334A (ja) * 1994-04-08 1998-03-03 レセプタゲン・コーポレーション 受容体調節剤およびこれに関連した方法
US5840880A (en) * 1994-04-08 1998-11-24 Receptagen Corporation Receptor modulating agents
US5739287A (en) * 1994-04-08 1998-04-14 University Of Washington Biotinylated cobalamins
US5739313A (en) * 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
US20010051346A1 (en) * 1998-09-18 2001-12-13 Erling Sundrehagen Assay
GB9820473D0 (en) * 1998-09-18 1998-11-11 Axis Biochemicals Asa Assay
US6806363B1 (en) * 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
JP2003531105A (ja) 1999-10-15 2003-10-21 メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ 造影剤および治療薬として有用なコバラミン結合体
US7591995B2 (en) 1999-10-15 2009-09-22 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
EP1231942A1 (en) * 1999-10-15 2002-08-21 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging agents and as antitumor agents
DE60043942D1 (de) * 1999-10-26 2010-04-15 Univ Utah Res Found Fluoreszierende cobalamine und deren verwendung
US6797521B2 (en) 1999-10-26 2004-09-28 University Of Utah Research Foundation Fluorescent cobalamins and uses thereof
TWI228512B (en) * 2000-10-25 2005-03-01 Mayo Foundation Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
NZ528714A (en) * 2001-03-16 2005-07-29 Univ Utah Res Found Fluorescent cobalamins and uses thereof to detect cancerous cells
AU2002322275A1 (en) * 2001-06-20 2003-01-08 Mayo Foundation For Medical Education And Research Adenosyl-cobalamin fortified compositions
US20060074034A1 (en) * 2001-09-17 2006-04-06 Collins Douglas A Cobalamin mediated delivery of nucleic acids, analogs and derivatives thereof
JP2005508332A (ja) * 2001-09-28 2005-03-31 メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ 薬剤を送達するための、輸送タンパク質とコンジュゲートコバラミンとの同時投与
KR100440725B1 (ko) * 2002-06-20 2004-07-15 주식회사 그린진 바이오텍 비생물성 스트레스에 대한 단자엽 식물의 내성을증가시키는 방법
WO2005061527A1 (en) * 2003-12-22 2005-07-07 Solidago Ag Cobalamine derivatives useful for diagnosis and treatment of abnormal cellular proliferation
CN101222853B (zh) * 2005-05-17 2012-07-18 卡吉尔公司 粒状卵磷脂、粒状溶血卵磷脂、它们的生产方法和包含它们的组合物
US8140141B2 (en) * 2006-05-17 2012-03-20 University Of Utah Research Foundation Devices and methods for fluorescent inspection and/or removal of material in a sample
US9120858B2 (en) 2011-07-22 2015-09-01 The Research Foundation Of State University Of New York Antibodies to the B12-transcobalamin receptor
GB202018713D0 (en) * 2020-11-27 2021-01-13 Quadram Inst Bioscience Methods and compositions utilising vitamin b12 binding

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5372M (OSRAM) * 1966-02-10 1967-10-16
US3989812A (en) * 1974-08-09 1976-11-02 Smithkline Instruments, Inc. Folic acid derivatives and use in radio-assay
US3937799A (en) * 1974-08-26 1976-02-10 Bio-Rad Laboratories Radioassay of vitamin b-12 employing bentonite
US3981863A (en) * 1975-02-25 1976-09-21 Micromedic Diagonistics, Inc. Cyanocobalamin derivatives
US4336185A (en) * 1976-03-02 1982-06-22 Rohm And Haas Company Folic acid derivatives
US4276280A (en) * 1976-09-29 1981-06-30 Becton, Dickinson And Company Radiolabeled derivatives of folic acid
US4209614A (en) * 1978-05-30 1980-06-24 E. R. Squibb & Sons, Inc. Vitamin B12 derivative suitable for radiolabeling
US4298735A (en) * 1979-04-30 1981-11-03 Union Carbide Corporation Folic acid derivatives

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9319735B2 (en) 1995-06-07 2016-04-19 Rovi Guides, Inc. Electronic television program guide schedule system and method with data feed access
US9191722B2 (en) 1997-07-21 2015-11-17 Rovi Guides, Inc. System and method for modifying advertisement responsive to EPG information
US9226006B2 (en) 1998-07-14 2015-12-29 Rovi Guides, Inc. Client-server based interactive guide with server recording
US9055318B2 (en) 1998-07-14 2015-06-09 Rovi Guides, Inc. Client-server based interactive guide with server storage
US9055319B2 (en) 1998-07-14 2015-06-09 Rovi Guides, Inc. Interactive guide with recording
US9118948B2 (en) 1998-07-14 2015-08-25 Rovi Guides, Inc. Client-server based interactive guide with server recording
US9154843B2 (en) 1998-07-14 2015-10-06 Rovi Guides, Inc. Client-server based interactive guide with server recording
US9232254B2 (en) 1998-07-14 2016-01-05 Rovi Guides, Inc. Client-server based interactive television guide with server recording
US9021538B2 (en) 1998-07-14 2015-04-28 Rovi Guides, Inc. Client-server based interactive guide with server recording
US9426509B2 (en) 1998-08-21 2016-08-23 Rovi Guides, Inc. Client-server electronic program guide
US9055322B2 (en) 2001-02-21 2015-06-09 Rovi Guides, Inc. Systems and methods for interactive program guides with personal video recording features
US8989561B1 (en) 2008-05-29 2015-03-24 Rovi Guides, Inc. Systems and methods for alerting users of the postponed recording of programs
US9125169B2 (en) 2011-12-23 2015-09-01 Rovi Guides, Inc. Methods and systems for performing actions based on location-based rules

Also Published As

Publication number Publication date
DE3262956D1 (en) 1985-05-15
EP0069450B1 (en) 1985-04-10
JPS58997A (ja) 1983-01-06
CA1180273A (en) 1985-01-02
US4465775A (en) 1984-08-14
EP0069450A1 (en) 1983-01-12

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