DE3262956D1 - Labelled vitamin b12 derivatives, their preparation and use - Google Patents

Labelled vitamin b12 derivatives, their preparation and use

Info

Publication number
DE3262956D1
DE3262956D1 DE8282302523T DE3262956T DE3262956D1 DE 3262956 D1 DE3262956 D1 DE 3262956D1 DE 8282302523 T DE8282302523 T DE 8282302523T DE 3262956 T DE3262956 T DE 3262956T DE 3262956 D1 DE3262956 D1 DE 3262956D1
Authority
DE
Germany
Prior art keywords
derivatives
preparation
labelled vitamin
labelled
vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282302523T
Other languages
English (en)
Inventor
Thomas Michael Houts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Technicon Instruments Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technicon Instruments Corp filed Critical Technicon Instruments Corp
Application granted granted Critical
Publication of DE3262956D1 publication Critical patent/DE3262956D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE8282302523T 1981-06-22 1982-05-18 Labelled vitamin b12 derivatives, their preparation and use Expired DE3262956D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8119147 1981-06-22

Publications (1)

Publication Number Publication Date
DE3262956D1 true DE3262956D1 (en) 1985-05-15

Family

ID=10522711

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282302523T Expired DE3262956D1 (en) 1981-06-22 1982-05-18 Labelled vitamin b12 derivatives, their preparation and use

Country Status (5)

Country Link
US (1) US4465775A (de)
EP (1) EP0069450B1 (de)
JP (1) JPS58997A (de)
CA (1) CA1180273A (de)
DE (1) DE3262956D1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ217821A (en) * 1985-10-10 1989-07-27 Biotech Australia Pty Ltd Oral delivery system; complex of active agent and vitamin b12 or analogue thereof
US5807832A (en) * 1987-06-09 1998-09-15 Biotech Australia Pty Limited Oral delivery of biologically active substances bound to vitamin B12
JPH03500003U (de) * 1988-06-15 1991-06-06
US4925931A (en) * 1988-07-14 1990-05-15 Mccully Kilmer S N-homocysteine thiolactonyl retinamido cobalamin and methods of use thereof
DE3900648A1 (de) * 1989-01-11 1990-07-12 Boehringer Mannheim Gmbh Neue cobalamin-saeurehydrazide und davon abgeleitete cobalamin-konjugate
US5405839A (en) * 1989-02-28 1995-04-11 Teijin Limited Vitamin B12 derivative, preparation process thereof, and use thereof
WO1990010014A1 (en) * 1989-02-28 1990-09-07 Teijin Limited New vitamin b12 derivative, production thereof, and application thereof
US5310656A (en) * 1989-06-26 1994-05-10 Tritech Partners Vitamin B12 assay
US5506109A (en) * 1989-06-26 1996-04-09 Bayer Corporation Vitamin B12 assay
CA1335707C (en) * 1989-08-15 1995-05-30 Pyare Khanna Drug screening assay
IE921050A1 (en) * 1991-04-02 1992-10-07 Biotech Australia Pty Ltd Oral delivery systems for microparticles
US6942977B1 (en) 1991-04-09 2005-09-13 Bio-Rad Laboratories, Inc. Immunoassays for determining vitamin b12, and reagents and kits therefor
JPH04363659A (ja) * 1991-06-10 1992-12-16 Smithkline Beckman Corp ビタミンｂ１２の分析
US5840880A (en) * 1994-04-08 1998-11-24 Receptagen Corporation Receptor modulating agents
US5739287A (en) * 1994-04-08 1998-04-14 University Of Washington Biotinylated cobalamins
ATE225799T1 (de) * 1994-04-08 2002-10-15 Receptagen Corp Rezeptor modulierendes mitteln und entsprechendes verfahren
US6769128B1 (en) 1995-06-07 2004-07-27 United Video Properties, Inc. Electronic television program guide schedule system and method with data feed access
US5739313A (en) * 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
AU733993B2 (en) 1997-07-21 2001-05-31 Rovi Guides, Inc. Systems and methods for displaying and recording control interfaces
CN1867068A (zh) 1998-07-14 2006-11-22 联合视频制品公司 交互式电视节目导视系统及其方法
US6898762B2 (en) 1998-08-21 2005-05-24 United Video Properties, Inc. Client-server electronic program guide
US20010051346A1 (en) * 1998-09-18 2001-12-13 Erling Sundrehagen Assay
GB9820473D0 (en) * 1998-09-18 1998-11-11 Axis Biochemicals Asa Assay
US6806363B1 (en) * 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
JP2003531105A (ja) 1999-10-15 2003-10-21 メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ 造影剤および治療薬として有用なコバラミン結合体
US7591995B2 (en) 1999-10-15 2009-09-22 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
KR20020059618A (ko) * 1999-10-15 2002-07-13 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 이미지화제 및 항종양제로서 유용한 코발라민 콘쥬게이트
NZ519129A (en) * 1999-10-26 2006-06-30 Univ Utah Res Found Fluorescent cobalamins and uses thereof
US6797521B2 (en) * 1999-10-26 2004-09-28 University Of Utah Research Foundation Fluorescent cobalamins and uses thereof
EP1334114A2 (de) * 2000-10-25 2003-08-13 Mayo Foundation For Medical Education And Research Transcobalamin-bindende konjugate zur behandlung abnormaler zellulärer proliferation
CA3011879C (en) 2001-02-21 2021-10-19 Rovi Guides, Inc. Systems and methods for interactive program guides with personal video recordng features
CA2441146C (en) * 2001-03-16 2011-08-09 University Of Utah Research Foundation Fluorescent cobalamins and uses thereof
AU2002322275A1 (en) * 2001-06-20 2003-01-08 Mayo Foundation For Medical Education And Research Adenosyl-cobalamin fortified compositions
US20060074034A1 (en) * 2001-09-17 2006-04-06 Collins Douglas A Cobalamin mediated delivery of nucleic acids, analogs and derivatives thereof
EP1435973A4 (de) * 2001-09-28 2007-05-02 Mayo Foundation Gleichzeitige verabreichung eines transportproteins mit konjugiertem cobalamin zur abgabe von mitteln
KR100440725B1 (ko) * 2002-06-20 2004-07-15 주식회사 그린진 바이오텍 비생물성 스트레스에 대한 단자엽 식물의 내성을증가시키는 방법
NZ548009A (en) * 2003-12-22 2010-03-26 Solidago Ag Cobalamine derivatives useful for diagnosis and treatment of abnormal cellular proliferation
US8535750B2 (en) * 2005-05-17 2013-09-17 Cargill, Incorporated Granular lecithins, granular lysolecithins, process for their production and compositions containing them
US8140141B2 (en) * 2006-05-17 2012-03-20 University Of Utah Research Foundation Devices and methods for fluorescent inspection and/or removal of material in a sample
US8989561B1 (en) 2008-05-29 2015-03-24 Rovi Guides, Inc. Systems and methods for alerting users of the postponed recording of programs
US9120858B2 (en) 2011-07-22 2015-09-01 The Research Foundation Of State University Of New York Antibodies to the B12-transcobalamin receptor
US8805418B2 (en) 2011-12-23 2014-08-12 United Video Properties, Inc. Methods and systems for performing actions based on location-based rules
GB202018713D0 (en) * 2020-11-27 2021-01-13 Quadram Inst Bioscience Methods and compositions utilising vitamin b12 binding

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5372M (de) * 1966-02-10 1967-10-16
US3989812A (en) * 1974-08-09 1976-11-02 Smithkline Instruments, Inc. Folic acid derivatives and use in radio-assay
US3937799A (en) * 1974-08-26 1976-02-10 Bio-Rad Laboratories Radioassay of vitamin b-12 employing bentonite
US3981863A (en) * 1975-02-25 1976-09-21 Micromedic Diagonistics, Inc. Cyanocobalamin derivatives
US4336185A (en) * 1976-03-02 1982-06-22 Rohm And Haas Company Folic acid derivatives
US4276280A (en) * 1976-09-29 1981-06-30 Becton, Dickinson And Company Radiolabeled derivatives of folic acid
US4209614A (en) * 1978-05-30 1980-06-24 E. R. Squibb & Sons, Inc. Vitamin B12 derivative suitable for radiolabeling
US4298735A (en) * 1979-04-30 1981-11-03 Union Carbide Corporation Folic acid derivatives

Also Published As

Publication number Publication date
US4465775A (en) 1984-08-14
JPS58997A (ja) 1983-01-06
EP0069450A1 (de) 1983-01-12
JPH0553378B2 (de) 1993-08-09
CA1180273A (en) 1985-01-02
EP0069450B1 (de) 1985-04-10

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: TECHNICON INSTRUMENTS CORP. (N.D.GES.D.STAATES DEL

8339 Ceased/non-payment of the annual fee