JPH05504343A - Ｍｒ―診断用の遷移金属錯体 - Google Patents

Ｍｒ―診断用の遷移金属錯体

Info

Publication number
JPH05504343A
JPH05504343A JP50207891A JP50207891A JPH05504343A JP H05504343 A JPH05504343 A JP H05504343A JP 50207891 A JP50207891 A JP 50207891A JP 50207891 A JP50207891 A JP 50207891A JP H05504343 A JPH05504343 A JP H05504343A
Authority
JP
Japan
Prior art keywords
hydrogen
general formula
transition metal
iron
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP50207891A
Other languages
English (en)
Japanese (ja)
Inventor
クリューガー，ウーヴェ
ルップ，ヘルベルト
ベラー，クラウス―ディーター
クレイ，ハンス―ペーター
Original Assignee
ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング filed Critical ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング
Publication of JPH05504343A publication Critical patent/JPH05504343A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP50207891A 1990-01-09 1991-01-08 Ｍｒ―診断用の遷移金属錯体 Pending JPH05504343A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH6290A CH679742A5 (pt) 1990-01-09 1990-01-09
CH62/90-7 1990-01-09

Publications (1)

Publication Number Publication Date
JPH05504343A true JPH05504343A (ja) 1993-07-08

Family

ID=4178448

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50207891A Pending JPH05504343A (ja) 1990-01-09 1991-01-08 Ｍｒ―診断用の遷移金属錯体

Country Status (5)

Country Link
EP (1) EP0510030A1 (pt)
JP (1) JPH05504343A (pt)
AU (1) AU7044791A (pt)
CH (1) CH679742A5 (pt)
WO (1) WO1991010454A1 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016519112A (ja) * 2013-04-25 2016-06-30 バイエル・ファルマ・アクティエンゲゼルシャフト Ｘ線画像化のためのビスアザイノシトールハフニウム錯体

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4028139A1 (de) * 1990-09-05 1992-03-12 Hausmann Ag Labor Verwendung der komplexe radioaktiver metallionen mit all-cis-1,3,5-triamino-2,4,6-cyclohexantriol und seinen derivaten fuer roentgendiagnostische zwecke und in der tumortherapie sowie zur herstellung von mitteln fuer roentgendiagnostische zwecke und fuer die tumortherapie
JP2894879B2 (ja) * 1991-10-04 1999-05-24 日本メジフィジックス株式会社 診断用造影剤
JP5172162B2 (ja) 2006-08-25 2013-03-27 株式会社日立ハイテクノロジーズ 欠陥検査装置
CN104321082A (zh) 2012-05-18 2015-01-28 拜耳医药股份有限公司 用于x射线成像的双氮杂肌醇重金属络合物
EP2873670A1 (en) 2013-11-14 2015-05-20 Bayer Pharma Aktiengesellschaft Bis azainositol zirconium complexes for X-ray imaging

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3129906C3 (de) * 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
DE3503614A1 (de) * 1985-02-02 1986-08-07 Laboratorien Hausmann AG, St. Gallen All-cis-1,3,5-triamino-2,4,6-cyclohexantriol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate
DE3625417C2 (de) * 1986-07-28 1998-10-08 Schering Ag Tetraazacyclododecan-Derivate

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016519112A (ja) * 2013-04-25 2016-06-30 バイエル・ファルマ・アクティエンゲゼルシャフト Ｘ線画像化のためのビスアザイノシトールハフニウム錯体

Also Published As

Publication number Publication date
CH679742A5 (pt) 1992-04-15
WO1991010454A1 (de) 1991-07-25
EP0510030A1 (de) 1992-10-28
AU7044791A (en) 1991-08-05

Similar Documents

Publication Publication Date Title
DK170461B1 (da) Diagnostisk middel til anvendelse ved in vivo NMR-diagnostik, fremgangsmåde til fremstilling heraf samt komplekse salte velegnede til anvendelse i det diagnostiske middel
US5362475A (en) Gadolinium chelates for magnetic resonance imaging
US4916246A (en) Paramagnetic chelates useful for NMR imaging
US4647447A (en) Diagnostic media
CA1321346C (en) Nmr imaging with paramagnetic polyvalent metal salts of poly-(acid-alkylene-amino)-alkanes
US5804163A (en) Contrast agents for magnetic resonance imaging aminosaccharide
US5876695A (en) Metal complex-containing pharmaceutical agents
US5219553A (en) Composition of a n-carboxymethylated tetraazacyclododecane chelating agent, a paramagnetic metal and excess calcium ions for MRI
US5087440A (en) Heterocyclic derivatives of DTPA used for magnetic resonance imaging
US5403572A (en) Macrocyclic polyaza compounds containing 5 or 6 membered rings, process for producing them and pharmaceutical media containing them
JPS5829718A (ja) Ｎｍｒ―診断法において緩和時間に影響を及ぼす薬剤およびその製法
JPH04500964A (ja) キレート組成物
US5348954A (en) Heterocyclic chelating agents
JP3007415B2 (ja) ホスホネート部分と非ホスホネート部分との両者を有するｍｒｉ用のポリアミノ常磁性キレート
JP7145156B2 (ja) 二量体造影剤
JPH07508527A (ja) 錯体形成剤
ZA200501172B (en) Use of metal complexes containing perfluoroalkyl as contrast agents in magnetic resonance imaging for presenting intravascular thrombi
Urbanovský et al. Lanthanide complexes of DO3A–(dibenzylamino) methylphosphinate: effect of protonation of the dibenzylamino group on the water-exchange rate and the binding of human serum albumin
JPH09502198A (ja) コントラスト強化剤としてのキレート化剤
US5560903A (en) Method of enhancing paramagnetism in chelates for MRI
JPH05504343A (ja) Ｍｒ―診断用の遷移金属錯体
JPH06340556A (ja) イメージング剤としての大環状アミノホスホン酸錯体の使用
JPH04225925A (ja) 金属キレート造影剤用賦形剤
BR112021007707A2 (pt) formulação de meios de contraste e processo de preparação da mesma
WO1995017910A2 (en) Paramagnetic diagnostic formulations and their method of use