JPH0528627B2 - - Google Patents
Info
- Publication number
- JPH0528627B2 JPH0528627B2 JP1266234A JP26623489A JPH0528627B2 JP H0528627 B2 JPH0528627 B2 JP H0528627B2 JP 1266234 A JP1266234 A JP 1266234A JP 26623489 A JP26623489 A JP 26623489A JP H0528627 B2 JPH0528627 B2 JP H0528627B2
- Authority
- JP
- Japan
- Prior art keywords
- calcium phosphate
- cement composition
- weight
- cement
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 claims description 62
- 239000004568 cement Substances 0.000 claims description 57
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 37
- 239000001506 calcium phosphate Substances 0.000 claims description 29
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 29
- 235000011010 calcium phosphates Nutrition 0.000 claims description 29
- 239000007788 liquid Substances 0.000 claims description 28
- 150000004676 glycans Chemical class 0.000 claims description 12
- 229920001282 polysaccharide Polymers 0.000 claims description 12
- 239000005017 polysaccharide Substances 0.000 claims description 12
- 239000011575 calcium Substances 0.000 claims description 8
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 6
- 229920001661 Chitosan Polymers 0.000 claims description 6
- 229920002674 hyaluronan Polymers 0.000 claims description 6
- 229960003160 hyaluronic acid Drugs 0.000 claims description 6
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims description 5
- 229920002101 Chitin Polymers 0.000 claims description 5
- 229920001287 Chondroitin sulfate Polymers 0.000 claims description 5
- 229920002527 Glycogen Polymers 0.000 claims description 5
- 229920000084 Gum arabic Polymers 0.000 claims description 5
- 229920002472 Starch Polymers 0.000 claims description 5
- 239000000205 acacia gum Substances 0.000 claims description 5
- 235000010489 acacia gum Nutrition 0.000 claims description 5
- XAAHAAMILDNBPS-UHFFFAOYSA-L calcium hydrogenphosphate dihydrate Chemical compound O.O.[Ca+2].OP([O-])([O-])=O XAAHAAMILDNBPS-UHFFFAOYSA-L 0.000 claims description 5
- 229940059329 chondroitin sulfate Drugs 0.000 claims description 5
- 229940096919 glycogen Drugs 0.000 claims description 5
- 239000008107 starch Substances 0.000 claims description 5
- 235000019698 starch Nutrition 0.000 claims description 5
- 235000019731 tricalcium phosphate Nutrition 0.000 claims description 4
- 239000011812 mixed powder Substances 0.000 claims description 2
- 241000978776 Senegalia senegal Species 0.000 claims 1
- OKJPEAGHQZHRQV-UHFFFAOYSA-N iodoform Chemical compound IC(I)I OKJPEAGHQZHRQV-UHFFFAOYSA-N 0.000 description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 12
- 239000000126 substance Substances 0.000 description 10
- 238000004898 kneading Methods 0.000 description 9
- 239000002202 Polyethylene glycol Substances 0.000 description 7
- 210000000988 bone and bone Anatomy 0.000 description 7
- 229920001223 polyethylene glycol Polymers 0.000 description 7
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 6
- KXKPYJOVDUMHGS-OSRGNVMNSA-N chondroitin sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](OS(O)(=O)=O)[C@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O1 KXKPYJOVDUMHGS-OSRGNVMNSA-N 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 230000000844 anti-bacterial effect Effects 0.000 description 5
- 244000215068 Acacia senegal Species 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 4
- RBLGLDWTCZMLRW-UHFFFAOYSA-K dicalcium;phosphate;dihydrate Chemical compound O.O.[Ca+2].[Ca+2].[O-]P([O-])([O-])=O RBLGLDWTCZMLRW-UHFFFAOYSA-K 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 239000004372 Polyvinyl alcohol Substances 0.000 description 3
- 239000003242 anti bacterial agent Substances 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 239000002872 contrast media Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 3
- 230000007935 neutral effect Effects 0.000 description 3
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 229940036348 bismuth carbonate Drugs 0.000 description 2
- -1 calcium phosphate compound Chemical class 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 210000004262 dental pulp cavity Anatomy 0.000 description 2
- GMZOPRQQINFLPQ-UHFFFAOYSA-H dibismuth;tricarbonate Chemical compound [Bi+3].[Bi+3].[O-]C([O-])=O.[O-]C([O-])=O.[O-]C([O-])=O GMZOPRQQINFLPQ-UHFFFAOYSA-H 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- 235000014469 Bacillus subtilis Nutrition 0.000 description 1
- 241001474374 Blennius Species 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
- 241000238424 Crustacea Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 239000003929 acidic solution Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 229910052586 apatite Inorganic materials 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000003462 bioceramic Substances 0.000 description 1
- 229910052797 bismuth Inorganic materials 0.000 description 1
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 description 1
- JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 description 1
- 229940043256 calcium pyrophosphate Drugs 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000003479 dental cement Substances 0.000 description 1
- AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 description 1
- 235000019821 dicalcium diphosphate Nutrition 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 229910052587 fluorapatite Inorganic materials 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000009036 growth inhibition Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 229910001410 inorganic ion Inorganic materials 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 239000002631 root canal filling material Substances 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000006150 trypticase soy agar Substances 0.000 description 1
Landscapes
- Curing Cements, Concrete, And Artificial Stone (AREA)
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1266234A JPH03128061A (ja) | 1989-10-16 | 1989-10-16 | 水硬性リン酸カルシウムセメント組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1266234A JPH03128061A (ja) | 1989-10-16 | 1989-10-16 | 水硬性リン酸カルシウムセメント組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH03128061A JPH03128061A (ja) | 1991-05-31 |
| JPH0528627B2 true JPH0528627B2 (fr) | 1993-04-26 |
Family
ID=17428135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1266234A Granted JPH03128061A (ja) | 1989-10-16 | 1989-10-16 | 水硬性リン酸カルシウムセメント組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH03128061A (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5467554B2 (ja) | 2008-04-25 | 2014-04-09 | ＨＯＹＡ Ｔｅｃｈｎｏｓｕｒｇｉｃａｌ株式会社 | 粉末状のアパタイト／コラーゲン複合体、形状賦形型の人工骨ペースト、及びそれらの製造方法 |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59217666A (ja) * | 1983-05-26 | 1984-12-07 | 株式会社未来化学研究所 | 水酸化アパタイト焼結体及びその製法 |
| JPS61242968A (ja) * | 1985-04-01 | 1986-10-29 | ティーディーケイ株式会社 | 成形材料 |
| JPS6269823A (ja) * | 1986-09-12 | 1987-03-31 | Mitsubishi Mining & Cement Co Ltd | りん酸カルシウム質フアイバ− |
| JPS63143071A (ja) * | 1986-12-03 | 1988-06-15 | 永瀬 守 | リン酸三カルシウムと酸と多糖類と水を混合する事により硬化生成した人工骨 |
| JPS63201054A (ja) * | 1987-02-10 | 1988-08-19 | 科学技術庁無線材質研究所長 | アパタイト成形焼結体の製造方法 |
| JPH01100048A (ja) * | 1987-10-13 | 1989-04-18 | Asahi Optical Co Ltd | リン酸カルシウム系硬化体の製造方法 |
| JPH01148812A (ja) * | 1988-09-30 | 1989-06-12 | Mitsubishi Mining & Cement Co Ltd | 無機ファイバーの製造方法 |
| JPH01158965A (ja) * | 1987-12-16 | 1989-06-22 | Tokuyama Soda Co Ltd | 硬化性組成物 |
| EP0323632A1 (fr) * | 1987-12-28 | 1989-07-12 | Asahi Kogaku Kogyo Kabushiki Kaisha | Composition pour la fabrication d'un matériau durcissable du type phosphate de calcium et procédé pour la production d'un tel matériau |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6437445A (en) * | 1987-07-31 | 1989-02-08 | Nat Inst Res Inorganic Mat | Calcium phosphate hydraulic cement composition |
-
1989
- 1989-10-16 JP JP1266234A patent/JPH03128061A/ja active Granted
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59217666A (ja) * | 1983-05-26 | 1984-12-07 | 株式会社未来化学研究所 | 水酸化アパタイト焼結体及びその製法 |
| JPS61242968A (ja) * | 1985-04-01 | 1986-10-29 | ティーディーケイ株式会社 | 成形材料 |
| JPS6269823A (ja) * | 1986-09-12 | 1987-03-31 | Mitsubishi Mining & Cement Co Ltd | りん酸カルシウム質フアイバ− |
| JPS63143071A (ja) * | 1986-12-03 | 1988-06-15 | 永瀬 守 | リン酸三カルシウムと酸と多糖類と水を混合する事により硬化生成した人工骨 |
| JPS63201054A (ja) * | 1987-02-10 | 1988-08-19 | 科学技術庁無線材質研究所長 | アパタイト成形焼結体の製造方法 |
| JPH01100048A (ja) * | 1987-10-13 | 1989-04-18 | Asahi Optical Co Ltd | リン酸カルシウム系硬化体の製造方法 |
| JPH01158965A (ja) * | 1987-12-16 | 1989-06-22 | Tokuyama Soda Co Ltd | 硬化性組成物 |
| EP0323632A1 (fr) * | 1987-12-28 | 1989-07-12 | Asahi Kogaku Kogyo Kabushiki Kaisha | Composition pour la fabrication d'un matériau durcissable du type phosphate de calcium et procédé pour la production d'un tel matériau |
| JPH01148812A (ja) * | 1988-09-30 | 1989-06-12 | Mitsubishi Mining & Cement Co Ltd | 無機ファイバーの製造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH03128061A (ja) | 1991-05-31 |
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