JPH05208988A - ３−デオキシマンノサミン誘導体およびそれら誘導体の製法 - Google Patents

３−デオキシマンノサミン誘導体およびそれら誘導体の製法

Info

Publication number
JPH05208988A
JPH05208988A JP4227760A JP22776092A JPH05208988A JP H05208988 A JPH05208988 A JP H05208988A JP 4227760 A JP4227760 A JP 4227760A JP 22776092 A JP22776092 A JP 22776092A JP H05208988 A JPH05208988 A JP H05208988A
Authority
JP
Japan
Prior art keywords
dideoxy
mannopyranose
formula
compound
acetamido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4227760A
Other languages
English (en)
Japanese (ja)
Inventor
Nicola Mongelli
ニコラ・モンゲルリ
Alberto Bargiotti
アルベルト・バルジオッティ
Nuccia Oneto
ヌッチア・オネト
Cristina Geroni
クリスティーナ・ゲローニ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Publication of JPH05208988A publication Critical patent/JPH05208988A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02—Acyclic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP4227760A 1991-08-06 1992-08-05 ３−デオキシマンノサミン誘導体およびそれら誘導体の製法 Pending JPH05208988A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919116896A GB9116896D0 (en) 1991-08-06 1991-08-06 3-deoxymannosamine derivatives and process for their preparation
GB9116896.3 1991-08-06

Publications (1)

Publication Number Publication Date
JPH05208988A true JPH05208988A (ja) 1993-08-20

Family

ID=10699545

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4227760A Pending JPH05208988A (ja) 1991-08-06 1992-08-05 ３−デオキシマンノサミン誘導体およびそれら誘導体の製法

Country Status (16)

Country Link
US (1) US5332756A (enExample)
EP (1) EP0527042A2 (enExample)
JP (1) JPH05208988A (enExample)
KR (1) KR930004325A (enExample)
AU (1) AU646173B2 (enExample)
CA (1) CA2075336A1 (enExample)
FI (1) FI923498A7 (enExample)
GB (1) GB9116896D0 (enExample)
HU (1) HU213208B (enExample)
IL (1) IL102500A (enExample)
MX (1) MX9204395A (enExample)
MY (1) MY108749A (enExample)
NZ (1) NZ243627A (enExample)
RU (1) RU2099333C1 (enExample)
TW (1) TW248564B (enExample)
ZA (1) ZA925871B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010532388A (ja) * 2007-07-03 2010-10-07 チルドレンズ ホスピタル アンド リサーチ センター アット オークランド ポリシアル酸脱ｎ−アセチラーゼの阻害剤及びその使用方法
JP4943839B2 (ja) * 2004-05-26 2012-05-30 株式会社希少糖生産技術研究所 血管新生抑制剤

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
GB9304589D0 (en) * 1993-03-05 1993-04-21 Erba Carlo Spa Biologically active ureido derivatives useful as antimetastic agents
FR2723947B1 (fr) * 1994-08-31 1996-09-27 Adir Nouveaux composes tetrahydropyraniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
RU2266734C2 (ru) * 1999-05-13 2005-12-27 Фарма Мар, С.А. Композиции и применение ет743 для лечения злокачественных опухолей
US8148335B2 (en) 2004-06-23 2012-04-03 Children's Hospital & Research Center Oakland De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy
KR20070060069A (ko) * 2004-06-23 2007-06-12 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 다당류 유도체 및 면역반응의 유도에서의 용도
WO2007106886A2 (en) * 2006-03-15 2007-09-20 Trustees Of Tufts College Fluorinated carbohydrates and their use in tumor visualization, tissue engineering, and cancer chemotherapy
KR100780868B1 (ko) 2006-07-10 2007-11-30 부경대학교 산학협력단 항암효과를 나타내는 4급 아미노 글루코사민 화합물
AU2008272792B2 (en) 2007-07-03 2014-03-06 Children's Hospital & Research Center At Oakland Oligosialic acid derivatives, methods of manufacture, and immunological uses
CA2692417C (en) * 2007-07-03 2017-03-21 Children's Hospital & Research Center At Oakland Polysialic acid derivatives, methods of production, and uses in enhancing cancer antigen production and targeting
FR2930943B1 (fr) * 2008-05-07 2011-03-18 Centre Nat Rech Scient Nouvelles utilisations de derives de d-mannopyranose inhibiteurs de l'angiogenese

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4216208A (en) * 1978-07-31 1980-08-05 Proter S.P.A. N-Acyl derivatives of glucosamines having antitumor chemotherapeutic activity
US4647453A (en) * 1984-10-18 1987-03-03 Peritain, Ltd. Treatment for tissue degenerative inflammatory disease
DE3906174A1 (de) * 1989-02-28 1990-08-30 Forschungszentrum Juelich Gmbh Verfahren zur herstellung von d-mannosaminderivaten

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4943839B2 (ja) * 2004-05-26 2012-05-30 株式会社希少糖生産技術研究所 血管新生抑制剤
JP2010532388A (ja) * 2007-07-03 2010-10-07 チルドレンズ ホスピタル アンド リサーチ センター アット オークランド ポリシアル酸脱ｎ−アセチラーゼの阻害剤及びその使用方法

Also Published As

Publication number Publication date
IL102500A (en) 1996-01-19
KR930004325A (ko) 1993-03-22
IL102500A0 (en) 1993-01-14
HU213208B (en) 1997-03-28
AU2037492A (en) 1993-02-11
EP0527042A2 (en) 1993-02-10
RU2099333C1 (ru) 1997-12-20
CA2075336A1 (en) 1993-02-07
ZA925871B (en) 1993-04-28
EP0527042A3 (enExample) 1994-01-05
US5332756A (en) 1994-07-26
FI923498A0 (fi) 1992-08-03
HU9202329D0 (en) 1992-10-28
FI923498L (fi) 1993-02-07
GB9116896D0 (en) 1991-09-18
AU646173B2 (en) 1994-02-10
FI923498A7 (fi) 1993-02-07
HUT62593A (en) 1993-05-28
NZ243627A (en) 1994-04-27
MX9204395A (es) 1993-02-01
TW248564B (enExample) 1995-06-01
MY108749A (en) 1996-11-30

Similar Documents

Publication Publication Date Title
JP3717512B2 (ja) 新規スフィンゴ糖脂質およびその使用
CA1240989A (en) Homodisaccharide hypoglycemic agents
JPH05208988A (ja) ３−デオキシマンノサミン誘導体およびそれら誘導体の製法
Fuchs et al. Synthesis and antitumor activity of sugar-ring hydroxyl analogs of daunorubicin
WO1991013855A1 (en) Phenanthrene derivative
JP2516769B2 (ja) 新規なアントラサイクリン
JPH0660191B2 (ja) 新規アントラサイクリングリコシド類，それらの製造方法及びそれらを含む抗腫瘍剤
KR100547253B1 (ko) 암 예방 및 치료에 유효한 진세노사이드 유도체
EP2514759A1 (en) Triterpene derivative, and prophylactic or therapeutic agent for chronic hepatitis c
JP4105258B2 (ja) コレスタノール化合物及びこれを含有する医薬
JP4351314B2 (ja) コレスタノール化合物及びこれを含有する医薬
JP3831953B2 (ja) ７−グリコシロキシベンゾピラン誘導体及びそれを有効成分とする抗アレルギー剤
US5514658A (en) Oligosaccharides for inhibiting the mitosis of astrocytes and tumoral cells of the nervous system, and methods for obtaining them
JPH0560478B2 (enExample)
KR100564383B1 (ko) 진세노사이드 유도체의 제조방법
EP0374759A2 (de) Rhodomycine mit einer modifizierten Kohlenhydrat-Einheit
US5958889A (en) Anthracycline derivatives having 4-amino-2,4,6-trideoxy-2-fluoro-mannopyranosyl group
US6184365B1 (en) Anthracycline derivatives having 4-amino-2,4,6-trideoxy-2 fluoro-α-L-talopyranosyl group
JP3775514B2 (ja) ４−グリコシロキシベンゾピラン誘導体及びそれを有効成分とする抗アレルギー剤
JPH05202088A (ja) グリコシド及びこれを含有する抗肝炎剤
JP3775513B2 (ja) ３−グリコシロキシベンゾピラン誘導体及びそれを有効成分とする抗アレルギー剤
AU2523501A (en) Benzophenone glycopyranosides, preparation and therapeutic use
JPH0631297B2 (ja) 新規なアントラサイクリン類およびその製造方法
BG62289B1 (bg) Антрациклинови дизахариди, метод за тяхното получаване ифармацевтични състави на тяхна основа
JP2000086601A (ja) セラミド誘導体