JPH0480027B2 - - Google Patents

Info

Publication number
JPH0480027B2
JPH0480027B2 JP58040825A JP4082583A JPH0480027B2 JP H0480027 B2 JPH0480027 B2 JP H0480027B2 JP 58040825 A JP58040825 A JP 58040825A JP 4082583 A JP4082583 A JP 4082583A JP H0480027 B2 JPH0480027 B2 JP H0480027B2
Authority
JP
Japan
Prior art keywords
carbon atoms
dibenzo
dihydro
azepine
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58040825A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58180471A (ja
Inventor
Pesuterini Bitsutorio
Gerarudoni Mario
Gioritsutei Aresandoro
Borutera Giobana
Furio Maruchino
Meri Aruberutoo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AA MENARIINI Sas
Original Assignee
AA MENARIINI Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AA MENARIINI Sas filed Critical AA MENARIINI Sas
Publication of JPS58180471A publication Critical patent/JPS58180471A/ja
Publication of JPH0480027B2 publication Critical patent/JPH0480027B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP58040825A 1982-03-15 1983-03-14 ５，６−ジヒドロ−１１Ｈ−ジベンゾ（ｂ，ｅ）アゼピン−６−オン誘導体、その製造方法およびこれを含む医薬組成物 Granted JPS58180471A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8209356A IT1207417B (it) 1982-03-15 1982-03-15 Azepina-6-one ad attivita'composti triciclici derivati dalla farmacologica, e procedimenti di 5,6-diidro-11h-dibenzo (b,e)fabbricazione relativi
IT9356A/82 1982-03-15

Publications (2)

Publication Number Publication Date
JPS58180471A JPS58180471A (ja) 1983-10-21
JPH0480027B2 true JPH0480027B2 (en, 2012) 1992-12-17

Family

ID=11128909

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58040825A Granted JPS58180471A (ja) 1982-03-15 1983-03-14 ５，６−ジヒドロ−１１Ｈ−ジベンゾ（ｂ，ｅ）アゼピン−６−オン誘導体、その製造方法およびこれを含む医薬組成物

Country Status (22)

Country Link
US (1) US4551451A (en, 2012)
EP (1) EP0089322B1 (en, 2012)
JP (1) JPS58180471A (en, 2012)
AT (1) ATE27816T1 (en, 2012)
AU (1) AU562360B2 (en, 2012)
CA (1) CA1226282A (en, 2012)
DD (1) DD209452A5 (en, 2012)
DE (1) DE3217236C2 (en, 2012)
DK (1) DK158722C (en, 2012)
ES (1) ES8407479A1 (en, 2012)
GB (1) GB2116539B (en, 2012)
GR (1) GR78455B (en, 2012)
HU (1) HU189671B (en, 2012)
IE (1) IE54859B1 (en, 2012)
IT (1) IT1207417B (en, 2012)
MX (1) MX156434A (en, 2012)
NO (1) NO830877L (en, 2012)
PL (3) PL140327B1 (en, 2012)
PT (1) PT76372B (en, 2012)
SU (1) SU1301830A1 (en, 2012)
YU (1) YU63083A (en, 2012)
ZA (1) ZA831473B (en, 2012)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665664B2 (ja) * 1985-01-18 1994-08-24 大塚製薬株式会社 モルフアントリジン誘導体
IT1233715B (it) * 1989-07-14 1992-04-14 Menarini Farma Ind Uso in terapia della 10-ammino-5,6diidro-11h= dibenzo (b,e) azepina-6,11-dione e derivati, quali farmaci utili per il trattamento dell'incontinenza urinaria
DE4138853A1 (de) * 1991-11-27 1993-06-03 Bayer Ag 5,6-dihydro-dibenz(b,e)azepin-6,11-dion-11- oxime
AU3441193A (en) * 1992-04-14 1993-11-18 Sphinx Pharmaceuticals Corporation Polyhydroxylated dibenz (C,E) azepines as protein kinase C inhibitors
EP1027337A4 (en) * 1997-09-04 2002-04-03 Smithkline Beecham Corp Integrin receptor Antagonist
TWI297685B (en) * 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3084155A (en) * 1963-04-02 Derivatives of dibenzo
GB972082A (en) * 1961-06-07 1964-10-07 Koninklijke Pharma Fab Nv Dihydrodibenzazepinones
GB1062573A (en) * 1963-10-29 1967-03-22 Colgate Palmolive Co Morphanthridine derivatives,and processes of preparing the same
DE1545856A1 (de) * 1965-09-10 1969-11-27 Bayer Ag Verfahren zur Herstellung von basisch substituierten Derivaten des 5,6-Dihydro-dibenz-[b,e]-azepin-6,11-dion-11-oxims
DE1568217A1 (de) * 1966-12-16 1970-01-02 Boehringer Mannheim Gmbh Verfahren zur Herstellung von tricyclischen Derivaten des Acetamids
JPS4934996B1 (en, 2012) * 1969-05-06 1974-09-19
CH569730A5 (en, 2012) * 1972-04-04 1975-11-28 Wander Ag Dr A
CH577975A5 (en, 2012) * 1972-10-20 1976-07-30 Sandoz Ag
DE2361467A1 (de) * 1973-12-10 1975-06-19 Thiemann Chem Pharm Fab 1-amino-5,6-dihydro-morphanthridin5,11-dion-verbindungen und solche verbindungen enthaltende arzneimittel
CH601287A5 (en, 2012) * 1975-08-06 1978-07-14 Sandoz Ag
DE2918832A1 (de) * 1979-05-10 1980-11-20 Basf Ag 5,6-dihydro-11-alkylen-morphantridin- 6-one
DE2918778A1 (de) * 1979-05-10 1980-11-20 Basf Ag 6-substituierte 11-alkylen-morphantridine
DE3113094A1 (de) * 1981-04-01 1982-10-21 Basf Ag, 6700 Ludwigshafen 5,6-dihydro-11-alkylen-morphantridin-6-one, ihre herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
SU1301830A1 (ru) 1987-04-07
CA1226282A (en) 1987-09-01
PL140327B1 (en) 1987-04-30
ZA831473B (en) 1983-11-30
IT8209356A0 (it) 1982-03-15
DE3217236A1 (de) 1983-09-15
EP0089322A1 (en) 1983-09-21
DK158722C (da) 1990-12-03
GB2116539A (en) 1983-09-28
ES520577A0 (es) 1984-10-01
PL241018A1 (en) 1985-07-16
GB2116539B (en) 1986-04-30
EP0089322B1 (en) 1987-06-16
GR78455B (en, 2012) 1984-09-27
ES8407479A1 (es) 1984-10-01
IE54859B1 (en) 1990-02-28
YU63083A (en) 1989-08-31
MX156434A (es) 1988-08-22
DE3217236C2 (de) 1994-04-14
DK86483A (da) 1983-09-16
PT76372A (en) 1983-04-01
PT76372B (en) 1985-12-05
NO830877L (no) 1983-09-16
JPS58180471A (ja) 1983-10-21
IE830542L (en) 1983-09-15
AU1243183A (en) 1983-09-22
PL252303A1 (en) 1985-12-17
HU189671B (en) 1986-07-28
IT1207417B (it) 1989-05-17
DK158722B (da) 1990-07-09
AU562360B2 (en) 1987-06-11
ATE27816T1 (de) 1987-07-15
DK86483D0 (da) 1983-02-24
DD209452A5 (de) 1984-05-09
US4551451A (en) 1985-11-05

Similar Documents

Publication Publication Date Title
US4423044A (en) 3,4-Dihydro-5H-2,3-benzodiazepine derivatives and pharmaceutical use thereof
WO1992007830A2 (en) Oxindole peptide antagonists
JPS6089474A (ja) モルフイナン誘導体，その製造方法，及び該化合物を含有する抗腫瘍剤
US4532344A (en) Fluoranthene derivatives
US4659710A (en) 1,7-Naphthyridine derivatives and pharmaceutical compositions
GB2173195A (en) Pharmaceutical compositions
JPH0480027B2 (en, 2012)
EP0149419B1 (en) Acylindole derivatives and pharmaceutical compositions containing them
EP0093945B1 (en) 1,4-dihydropyridine derivatives
US4785018A (en) Glycine derivatives
HU197746B (en) Process for producing xantin derivatives and pharmaceutical compositions containing them
JP3575610B2 (ja) 新規ベンゾピラノン、それらの製造方法およびそれらの使用
IE55095B1 (en) Substituted iminoderivatives of dihydrobenzopyran and dihydrobenzothiopyran and process for their preparation
EP0038298B1 (en) Isoxazolyl indolamines
US3980674A (en) 2,3-Disubstituted 7-oxabicyclo-[2.2.1]-5-heptene
EP0397210A1 (en) Indole derivative and method of production thereof
EP0663395B1 (de) 3-(Phenylalkylaminoalkyloxy)-5-phenylpyrazol-Derivate, Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung als herzfrequenzsenkendes Mittel
US4048321A (en) Disubstituted azabicycloalkanes
USRE28377E (en) Selected s.substituted-s-phenylalkyl barbituric acids
EP0090275A2 (en) Isoxazole (5,4-b) pyridines
US3635962A (en) 4 - bis-morpholino- and 2
US4841097A (en) Dialkanoyloxybenzylidene dialkanoate
HU191597B (en) Process for producing of 2-/2-indalin/-imadazoline preparates and medical preparates consisting of such substances
US4605660A (en) Indeno[2,1-c]pyridine compounds, and their use as calcium channel blockers
JP2790335B2 (ja) 共役γ―オキシブテノライド化合物およびこれを有効成分とする抗潰瘍剤