JPH0475890B2 - - Google Patents
Info
- Publication number
- JPH0475890B2 JPH0475890B2 JP60164044A JP16404485A JPH0475890B2 JP H0475890 B2 JPH0475890 B2 JP H0475890B2 JP 60164044 A JP60164044 A JP 60164044A JP 16404485 A JP16404485 A JP 16404485A JP H0475890 B2 JPH0475890 B2 JP H0475890B2
- Authority
- JP
- Japan
- Prior art keywords
- present
- cell differentiation
- weight
- promoting
- nerve cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 210000002569 neuron Anatomy 0.000 claims description 35
- 230000024245 cell differentiation Effects 0.000 claims description 18
- 230000001737 promoting effect Effects 0.000 description 18
- 239000003795 chemical substances by application Substances 0.000 description 12
- 230000000694 effects Effects 0.000 description 10
- 230000004069 differentiation Effects 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 239000000284 extract Substances 0.000 description 7
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 6
- 239000000843 powder Substances 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 5
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 description 4
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 4
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 description 4
- 244000273928 Zingiber officinale Species 0.000 description 4
- 235000006886 Zingiber officinale Nutrition 0.000 description 4
- 244000126002 Ziziphus vulgaris Species 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 235000008397 ginger Nutrition 0.000 description 4
- 229940010454 licorice Drugs 0.000 description 4
- 238000001000 micrograph Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 208000024827 Alzheimer disease Diseases 0.000 description 3
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 3
- 244000000626 Daucus carota Species 0.000 description 3
- 235000002767 Daucus carota Nutrition 0.000 description 3
- 206010012289 Dementia Diseases 0.000 description 3
- 241000202807 Glycyrrhiza Species 0.000 description 3
- 206010039966 Senile dementia Diseases 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 235000017803 cinnamon Nutrition 0.000 description 3
- 208000035475 disorder Diseases 0.000 description 3
- 239000008187 granular material Substances 0.000 description 3
- 235000019359 magnesium stearate Nutrition 0.000 description 3
- 230000004031 neuronal differentiation Effects 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 241000208340 Araliaceae Species 0.000 description 2
- 241000736199 Paeonia Species 0.000 description 2
- 235000006484 Paeonia officinalis Nutrition 0.000 description 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 description 2
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 2
- 238000011047 acute toxicity test Methods 0.000 description 2
- 230000002490 cerebral effect Effects 0.000 description 2
- 208000026106 cerebrovascular disease Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 206010015037 epilepsy Diseases 0.000 description 2
- 210000003754 fetus Anatomy 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 235000008434 ginseng Nutrition 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000002241 neurite Anatomy 0.000 description 2
- 229940124597 therapeutic agent Drugs 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 244000303040 Glycyrrhiza glabra Species 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 208000036626 Mental retardation Diseases 0.000 description 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 208000018737 Parkinson disease Diseases 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000002567 autonomic effect Effects 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 210000003710 cerebral cortex Anatomy 0.000 description 1
- 239000008989 cinnamomi cortex Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 231100000517 death Toxicity 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000007902 hard capsule Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 229960002289 nicardipine hydrochloride Drugs 0.000 description 1
- AIKVCUNQWYTVTO-UHFFFAOYSA-N nicardipine hydrochloride Chemical compound Cl.COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN(C)CC=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 AIKVCUNQWYTVTO-UHFFFAOYSA-N 0.000 description 1
- 208000005346 nocturnal enuresis Diseases 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000002636 symptomatic treatment Methods 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60164044A JPS6226229A (ja) | 1985-07-26 | 1985-07-26 | 神経細胞分化促進剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60164044A JPS6226229A (ja) | 1985-07-26 | 1985-07-26 | 神経細胞分化促進剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6226229A JPS6226229A (ja) | 1987-02-04 |
| JPH0475890B2 true JPH0475890B2 (de) | 1992-12-02 |
Family
ID=15785733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60164044A Granted JPS6226229A (ja) | 1985-07-26 | 1985-07-26 | 神経細胞分化促進剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6226229A (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04275224A (ja) * | 1991-03-02 | 1992-09-30 | Kissei Pharmaceut Co Ltd | 痴呆症治療剤 |
| JP5054863B2 (ja) | 1997-11-04 | 2012-10-24 | 帝國製薬株式会社 | 潰瘍性大腸炎治療剤 |
| KR100382564B1 (ko) * | 1998-05-14 | 2003-07-16 | 김기영 | 치매병 예방 및 치료용 생약조성물 |
| KR20000002473A (ko) * | 1998-06-20 | 2000-01-15 | 신민규 | 퇴행성 대뇌 신경계 질환의 예방 및 치료제 |
| WO2003006039A1 (en) * | 2001-07-11 | 2003-01-23 | Regen Biotech, Inc. | A composition for the protection and regeneration of nerve cells containing the extract of scutellaria radix |
| JP2006206584A (ja) * | 2004-12-27 | 2006-08-10 | Tohoku Univ | アミロイドβ蛋白の凝集抑制剤、凝集アミロイドβ蛋白の分解剤、抗痴呆薬および抗痴呆性食品 |
| WO2009055769A1 (en) * | 2007-10-25 | 2009-04-30 | Phytoceutica, Inc. | Use of phy906 as treatment for inflammatory bowel disease and/or irritable bowel syndrome |
| US20110171329A1 (en) * | 2009-07-24 | 2011-07-14 | Henrich Cheng | Method for treatment of neural injuries |
| CN103920112A (zh) * | 2014-03-28 | 2014-07-16 | 徐明秀 | 一种用于治疗震颤麻痹的中药颗粒及其检验方法 |
| CN105169155A (zh) * | 2015-09-06 | 2015-12-23 | 崔红霞 | 治疗小儿遗尿症的中药 |
-
1985
- 1985-07-26 JP JP60164044A patent/JPS6226229A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6226229A (ja) | 1987-02-04 |
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