JPH0460549B2 - - Google Patents
Info
- Publication number
- JPH0460549B2 JPH0460549B2 JP60225439A JP22543985A JPH0460549B2 JP H0460549 B2 JPH0460549 B2 JP H0460549B2 JP 60225439 A JP60225439 A JP 60225439A JP 22543985 A JP22543985 A JP 22543985A JP H0460549 B2 JPH0460549 B2 JP H0460549B2
- Authority
- JP
- Japan
- Prior art keywords
- sensitive body
- substance
- substrate
- detected
- field
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000126 substance Substances 0.000 claims description 33
- 239000000758 substrate Substances 0.000 claims description 23
- 239000004065 semiconductor Substances 0.000 claims description 18
- 230000005669 field effect Effects 0.000 claims description 17
- 150000001875 compounds Chemical class 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims description 2
- 238000001514 detection method Methods 0.000 description 11
- 238000000034 method Methods 0.000 description 9
- 230000035945 sensitivity Effects 0.000 description 9
- 108090000790 Enzymes Proteins 0.000 description 8
- 102000004190 Enzymes Human genes 0.000 description 8
- 229940088598 enzyme Drugs 0.000 description 8
- 238000006243 chemical reaction Methods 0.000 description 7
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 6
- 239000008103 glucose Substances 0.000 description 6
- 239000012528 membrane Substances 0.000 description 5
- 230000003100 immobilizing effect Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000003486 chemical etching Methods 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- 239000013076 target substance Substances 0.000 description 2
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 1
- RGHNJXZEOKUKBD-SQOUGZDYSA-N Gluconic acid Natural products OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 235000012208 gluconic acid Nutrition 0.000 description 1
- 239000000174 gluconic acid Substances 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 230000020169 heat generation Effects 0.000 description 1
- 229920001600 hydrophobic polymer Polymers 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 210000003463 organelle Anatomy 0.000 description 1
- 230000010399 physical interaction Effects 0.000 description 1
- 238000001020 plasma etching Methods 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920005597 polymer membrane Polymers 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K7/00—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements
- G01K7/16—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements using resistive elements
- G01K7/18—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements using resistive elements the element being a linear resistance, e.g. platinum resistance thermometer
- G01K7/183—Measuring temperature based on the use of electric or magnetic elements directly sensitive to heat ; Power supply therefor, e.g. using thermoelectric elements using resistive elements the element being a linear resistance, e.g. platinum resistance thermometer characterised by the use of the resistive element
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/403—Cells and electrode assemblies
- G01N27/414—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS
- G01N27/4145—Ion-sensitive or chemical field-effect transistors, i.e. ISFETS or CHEMFETS specially adapted for biomolecules, e.g. gate electrode with immobilised receptors
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Testing Or Calibration Of Command Recording Devices (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60225439A JPS6283641A (ja) | 1985-10-08 | 1985-10-08 | 電界効果型半導体センサ |
DE19863634132 DE3634132C2 (de) | 1985-10-08 | 1986-10-07 | Biosensoreinrichtung |
GB8624094A GB2183344B (en) | 1985-10-08 | 1986-10-08 | Sensor |
US07/579,195 US5140393A (en) | 1985-10-08 | 1990-09-05 | Sensor device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60225439A JPS6283641A (ja) | 1985-10-08 | 1985-10-08 | 電界効果型半導体センサ |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6283641A JPS6283641A (ja) | 1987-04-17 |
JPH0460549B2 true JPH0460549B2 (sh) | 1992-09-28 |
Family
ID=16829380
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP60225439A Granted JPS6283641A (ja) | 1985-10-08 | 1985-10-08 | 電界効果型半導体センサ |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS6283641A (sh) |
DE (1) | DE3634132C2 (sh) |
GB (1) | GB2183344B (sh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008116210A (ja) * | 2006-10-31 | 2008-05-22 | Mitsumi Electric Co Ltd | センサおよび検出方法 |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4928513A (en) * | 1986-07-29 | 1990-05-29 | Sharp Kabushiki Kaisha | Sensor |
GB2224356A (en) * | 1988-10-31 | 1990-05-02 | Plessey Co Plc | Biosensor device |
EP0390692A3 (en) * | 1989-03-29 | 1991-10-02 | Terumo Kabushiki Kaisha | Method of forming thin film, apparatus for forming thin film and sensor |
FR2652652B1 (fr) * | 1989-10-02 | 1991-12-13 | Commissariat Energie Atomique | Procede et dispositif de detection d'especes chimiques au moyen d'un film mince de semiconducteur inorganique. |
EP0645621A3 (de) * | 1993-09-28 | 1995-11-08 | Siemens Ag | Sensoranordnung. |
USRE40209E1 (en) | 1994-06-13 | 2008-04-01 | Matsushita Electric Industrial Co., Ltd. | Cell potential measurement apparatus having a plurality of microelectrodes |
US5563067A (en) | 1994-06-13 | 1996-10-08 | Matsushita Electric Industrial Co., Ltd. | Cell potential measurement apparatus having a plurality of microelectrodes |
DE4427921C2 (de) * | 1994-08-06 | 2002-09-26 | Forschungszentrum Juelich Gmbh | Chemische Sensoren, insbesondere Biosensoren, auf Siliciumbasis |
DE19859998C2 (de) * | 1998-12-23 | 2000-11-30 | Siemens Ag | Gassensor und Verfahren zu dessen Herstellung |
SE0102426D0 (sv) * | 2001-07-06 | 2001-07-06 | Bioett Ab | Fuktsensor |
ES2347540T3 (es) * | 2001-12-21 | 2010-11-02 | Bae Systems Plc | Sistema sensor. |
US6852996B2 (en) * | 2002-09-25 | 2005-02-08 | Stmicroelectronics, Inc. | Organic semiconductor sensor device |
JP4232108B2 (ja) * | 2005-05-20 | 2009-03-04 | セイコーエプソン株式会社 | 標的物質の検出または定量方法、該方法に用いられる電極基板、装置、およびキット |
EP1767934B1 (en) * | 2005-09-21 | 2007-12-05 | Adixen Sensistor AB | Hydrogen gas sensitive semiconductor sensor |
GB0522461D0 (en) | 2005-11-03 | 2005-12-14 | Immunoclin Ltd | Dactyl detector |
FI20060389L (fi) * | 2006-04-21 | 2007-10-22 | Environics Oy | Sensori |
JP5358061B2 (ja) * | 2007-02-28 | 2013-12-04 | インフィコン エービー | 改良された水素ガス感知半導体センサ |
KR101337673B1 (ko) * | 2007-03-15 | 2013-12-06 | 인피콘 아베 | 향상된 수소 가스 고감도 반도체 센서 |
JP5159453B2 (ja) * | 2008-06-13 | 2013-03-06 | ローム株式会社 | イオンセンサ |
US9134270B2 (en) * | 2010-03-25 | 2015-09-15 | Stichting Imec Nederland | Amorphous thin film for sensing |
US20130214332A1 (en) * | 2011-08-26 | 2013-08-22 | Diagtronix, Inc. | Nanogrid channel fin-fet transistor and biosensor |
JP5903872B2 (ja) * | 2011-12-19 | 2016-04-13 | 大日本印刷株式会社 | トランジスタ型センサ、およびトランジスタ型センサの製造方法 |
DE102014104219B4 (de) * | 2014-03-26 | 2019-09-12 | Heraeus Nexensos Gmbh | Keramikträger sowie Sensorelement, Heizelement und Sensormodul jeweils mit einem Keramikträger und Verfahren zur Herstellung eines Keramikträgers |
JP6569901B2 (ja) * | 2015-08-28 | 2019-09-04 | ラピスセミコンダクタ株式会社 | 半導体装置及び半導体装置の製造方法 |
DE102015220909A1 (de) * | 2015-10-27 | 2017-04-27 | Robert Bosch Gmbh | Verwenden eines ionensensitiven Feldeffekttransistors zum Messen einer Konzentration von Wasserstoffperoxid in einem Fluid |
DE102016101249A1 (de) * | 2015-11-02 | 2017-05-04 | Epcos Ag | Sensorelement und Verfahren zur Herstellung eines Sensorelements |
TWI669496B (zh) * | 2016-09-26 | 2019-08-21 | 美商羅門哈斯電子材料有限公司 | 氣體感測器及其製造方法 |
US11092567B2 (en) | 2017-03-21 | 2021-08-17 | International Business Machines Corporation | Biosensor electrode having three-dimensional structured sensing surfaces |
DE102017209269A1 (de) | 2017-06-01 | 2018-12-06 | Robert Bosch Gmbh | MEMS-Mediensensor |
CN113358608B (zh) * | 2020-03-06 | 2023-03-21 | 中国科学院化学研究所 | 气体传感器及其制备方法 |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51139289A (en) * | 1975-03-12 | 1976-12-01 | Univ Utah | Chemically sensitive fe converter |
JPS52139777A (en) * | 1976-05-14 | 1977-11-21 | Omron Tateisi Electronics Co | Fixed enzyme membrane |
JPS55140142A (en) * | 1979-03-20 | 1980-11-01 | Olympus Optical Co Ltd | Field-effect semiconductor sensor and its manufacture |
JPS56111454A (en) * | 1980-02-06 | 1981-09-03 | Kuraray Co Ltd | Fet sensor |
JPS58179348A (ja) * | 1982-04-14 | 1983-10-20 | Hokuriku Denki Kogyo Kk | Alの陽極酸化薄膜を用いた湿度センサ素子 |
JPS5921756B2 (ja) * | 1979-03-16 | 1984-05-22 | ロボツトグルツペン・エツチ・ビイ | 可撓腕 |
JPS59120945A (ja) * | 1982-12-28 | 1984-07-12 | Shinkosumosu Denki Kk | 水素選択性センサ |
JPS59151051A (ja) * | 1983-02-17 | 1984-08-29 | Matsushita Electric Works Ltd | 生体触媒電極 |
JPS6029653A (ja) * | 1983-07-29 | 1985-02-15 | Hitachi Ltd | ガスセンサ |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE322927B (sh) * | 1967-09-28 | 1970-04-20 | Asea Ab | |
US3616411A (en) * | 1968-09-16 | 1971-10-26 | Gen Electric | Partial pressure sensor |
FR2252041A5 (sh) * | 1973-11-16 | 1975-06-13 | Thomson Csf | |
FR2273276B1 (sh) * | 1974-05-27 | 1978-08-04 | Radiotechnique Compelec | |
GB1490066A (en) * | 1974-10-07 | 1977-10-26 | Johnson Matthey Co Ltd | Gas composition detection apparatus |
US4104605A (en) * | 1976-09-15 | 1978-08-01 | General Electric Company | Thin film strain gauge and method of fabrication |
JPS5825221B2 (ja) * | 1977-12-12 | 1983-05-26 | 株式会社クラレ | Fet比較電極 |
US4313338A (en) * | 1978-08-18 | 1982-02-02 | Matsushita Electric Industrial Co., Ltd. | Gas sensing device |
DE3041952A1 (de) * | 1979-11-13 | 1981-09-03 | Gould Inc., 60008 Rolling Meadows, Ill. | Verfahren zur erzeugung einer duennschicht-sensoranordnung |
US4340564A (en) * | 1980-07-21 | 1982-07-20 | Daryl Laboratories, Inc. | Immunoadsorptive surface coating for solid-phase immunosubstrate and solid-phase immunosubstrate |
ATE30780T1 (de) * | 1981-06-22 | 1987-11-15 | Battelle Memorial Institute | Verfahren zum bestimmen bioaktiver substanzen. |
GB2103786A (en) * | 1981-08-14 | 1983-02-23 | Ici Plc | Fibre optic sensor |
JPS5921756U (ja) * | 1982-08-02 | 1984-02-09 | 三菱レイヨン株式会社 | 酵素電極 |
CA1209681A (en) * | 1982-08-04 | 1986-08-12 | Exxon Research And Engineering Company | Optically enhanced thin film photovoltaic device using lithography defined random surfaces |
JPS59127879A (ja) * | 1983-01-12 | 1984-07-23 | Semiconductor Energy Lab Co Ltd | 光電変換装置およびその作製方法 |
US4515653A (en) * | 1983-04-30 | 1985-05-07 | Sharp Kabushiki Kaisha | Method for production of a moisture sensor |
JPS59206756A (ja) * | 1983-05-11 | 1984-11-22 | Hitachi Ltd | 参照電極を一体化したfet化学センサ− |
GB2142147A (en) * | 1983-06-24 | 1985-01-09 | Standard Telephones Cables Ltd | Gas sensor |
GB2162440B (en) * | 1984-08-02 | 1987-10-14 | Stc Plc | Optical fibres |
GB8423204D0 (en) * | 1984-09-14 | 1984-10-17 | Comtech Res Unit | Assay technique and equipment |
JPS61198040A (ja) * | 1984-12-08 | 1986-09-02 | テストターム・メステヒニーク・ゲー・エム・ベー・ハー・ウント・コンパニー | 光学式露点センサ− |
-
1985
- 1985-10-08 JP JP60225439A patent/JPS6283641A/ja active Granted
-
1986
- 1986-10-07 DE DE19863634132 patent/DE3634132C2/de not_active Expired - Fee Related
- 1986-10-08 GB GB8624094A patent/GB2183344B/en not_active Expired
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51139289A (en) * | 1975-03-12 | 1976-12-01 | Univ Utah | Chemically sensitive fe converter |
JPS52139777A (en) * | 1976-05-14 | 1977-11-21 | Omron Tateisi Electronics Co | Fixed enzyme membrane |
JPS5921756B2 (ja) * | 1979-03-16 | 1984-05-22 | ロボツトグルツペン・エツチ・ビイ | 可撓腕 |
JPS55140142A (en) * | 1979-03-20 | 1980-11-01 | Olympus Optical Co Ltd | Field-effect semiconductor sensor and its manufacture |
JPS56111454A (en) * | 1980-02-06 | 1981-09-03 | Kuraray Co Ltd | Fet sensor |
JPS58179348A (ja) * | 1982-04-14 | 1983-10-20 | Hokuriku Denki Kogyo Kk | Alの陽極酸化薄膜を用いた湿度センサ素子 |
JPS59120945A (ja) * | 1982-12-28 | 1984-07-12 | Shinkosumosu Denki Kk | 水素選択性センサ |
JPS59151051A (ja) * | 1983-02-17 | 1984-08-29 | Matsushita Electric Works Ltd | 生体触媒電極 |
JPS6029653A (ja) * | 1983-07-29 | 1985-02-15 | Hitachi Ltd | ガスセンサ |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008116210A (ja) * | 2006-10-31 | 2008-05-22 | Mitsumi Electric Co Ltd | センサおよび検出方法 |
Also Published As
Publication number | Publication date |
---|---|
GB2183344A (en) | 1987-06-03 |
JPS6283641A (ja) | 1987-04-17 |
DE3634132A1 (de) | 1987-04-16 |
DE3634132C2 (de) | 1993-10-14 |
GB8624094D0 (en) | 1986-11-12 |
GB2183344B (en) | 1990-03-14 |
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