JPH04202116A - Hair growing and trichogenous agent - Google Patents
Hair growing and trichogenous agentInfo
- Publication number
- JPH04202116A JPH04202116A JP2332728A JP33272890A JPH04202116A JP H04202116 A JPH04202116 A JP H04202116A JP 2332728 A JP2332728 A JP 2332728A JP 33272890 A JP33272890 A JP 33272890A JP H04202116 A JPH04202116 A JP H04202116A
- Authority
- JP
- Japan
- Prior art keywords
- hair
- hair growth
- trichogenous
- agent
- hair growing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004209 hair Anatomy 0.000 title abstract description 24
- 239000000284 extract Substances 0.000 claims abstract description 19
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 18
- 239000004615 ingredient Substances 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 230000001737 promoting effect Effects 0.000 claims abstract description 10
- 239000002904 solvent Substances 0.000 claims abstract description 7
- 125000005233 alkylalcohol group Chemical group 0.000 claims abstract description 4
- 241000184329 Evolvulus Species 0.000 claims abstract 3
- 230000003779 hair growth Effects 0.000 claims description 57
- 238000000605 extraction Methods 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract description 17
- 230000000694 effects Effects 0.000 abstract description 17
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract description 6
- 239000006071 cream Substances 0.000 abstract description 5
- 230000001256 tonic effect Effects 0.000 abstract description 5
- 239000006210 lotion Substances 0.000 abstract description 3
- 241000124846 Evolvulus alsinoides Species 0.000 abstract 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 abstract 1
- 240000001549 Ipomoea eriocarpa Species 0.000 description 11
- 235000005146 Ipomoea eriocarpa Nutrition 0.000 description 10
- 239000008213 purified water Substances 0.000 description 7
- 201000004384 Alopecia Diseases 0.000 description 4
- 241000699670 Mus sp. Species 0.000 description 4
- -1 Polyoxyethylene Polymers 0.000 description 4
- 239000003995 emulsifying agent Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000003676 hair loss Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 229940041616 menthol Drugs 0.000 description 3
- 235000015961 tonic Nutrition 0.000 description 3
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 2
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 235000013871 bee wax Nutrition 0.000 description 2
- 239000012166 beeswax Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 229940057995 liquid paraffin Drugs 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 239000004200 microcrystalline wax Substances 0.000 description 2
- 235000019808 microcrystalline wax Nutrition 0.000 description 2
- 239000012188 paraffin wax Substances 0.000 description 2
- 210000004761 scalp Anatomy 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 229940099259 vaseline Drugs 0.000 description 2
- 238000011735 C3H mouse Methods 0.000 description 1
- 208000001840 Dandruff Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 241000748228 Porophyllum gracile Species 0.000 description 1
- 230000006750 UV protection Effects 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 231100000360 alopecia Toxicity 0.000 description 1
- 208000004631 alopecia areata Diseases 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 229940125716 antipyretic agent Drugs 0.000 description 1
- 229940092738 beeswax Drugs 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000011814 protection agent Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 230000003813 thin hair Effects 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明は、新規な育毛・発毛料に関し、更に゛詳しくは
育毛−発毛促進効果の優れた育毛・発毛料を提供せんと
するものである。[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to a novel hair growth/hair growth agent, and more specifically, it is an object of the present invention to provide a hair growth/hair growth agent with an excellent hair growth/hair growth promoting effect. be.
現在、世の中には若禿げ、老人性の禿げ、円形脱毛症等
に代表される禿げが存在する。これらの現象は一般生活
を営むうえで羞恥心を伴うものであり、当該者の治療に
対する興味は尋常ではない。しかるにこれまでに提供さ
れ・る育毛・養毛材には各種の化合物、生薬抽出エキス
等が適用されているが顕著な効果を示すものがほとんど
な（、また、ある程度の効果を有するものには皮膚炎を
起こす程刺激が強く、連続使用が困難である等の欠点が
あった。Currently, there are baldness types such as premature baldness, senile baldness, alopecia areata, etc. in the world. These phenomena are accompanied by a sense of shame in daily life, and the person concerned is unusually interested in treatment. However, although various compounds and crude drug extracts have been applied to the hair growth and hair nourishing materials provided so far, most of them have not shown remarkable effects (and some have some degree of effect). It has drawbacks such as being highly irritating to the point of causing dermatitis and difficult to use continuously.
そのため、長期にわたる使用に十分耐えうる安全性を備
えかつ、養毛・発毛効果に優れた養毛・育毛促進成分を
探索し、これを配合した育毛・発毛料を開発することを
課題とした。Therefore, we set out to find a hair growth/hair growth promoting ingredient that is safe enough to withstand long-term use and has excellent hair growth/growth effects, and to develop a hair growth/hair growth agent containing this ingredient. .
本発明者らは、実用的な効果を有する育毛・発毛料を開
発すべく、長年に渡って研究を重ねてきた結果、アサガ
オカラクサの抽出物を外用することにより、優れた育毛
・発毛効果がもたらされることを見出した。As a result of many years of research in order to develop a hair growth agent with practical effects, the inventors of the present invention have found that by externally applying extracts of morning glory and hair growth, excellent hair growth and hair growth effects can be achieved. was found to be brought about.
本発明はか−る知見にもとづいてなされたものである。The present invention has been made based on this knowledge.
すなわち、本発明はアサガオカラクサを抽出溶媒で抽出
して得られる抽出物を育毛・発毛促進成分として含有す
ることを特徴とする育毛・発毛料であり、抽出溶媒が水
または低級アルキルアルコールから選ばれたものである
。That is, the present invention is a hair growth/hair growth agent characterized by containing an extract obtained by extracting morning glory morning glory with an extraction solvent as a hair growth/hair growth promoting ingredient, wherein the extraction solvent is selected from water or lower alkyl alcohol. It is something that was given.
以下、本発明の詳細な説明する。The present invention will be explained in detail below.
本発明で用いるアサガオカラクサとは、学名Ｅｖｏｌｖ
ｕｌｕｓ ａｌｓｉｎｏｉｄｅｓと呼ばれ１強壮剤、解
熱剤として有効な成分が全草にわたって存在することが
知られているが、これまで化粧料や育毛・発毛料に用い
られたことはない。The scientific name of morning glory odora used in the present invention is Evolv.
Although it is known that the whole plant contains ingredients called ulus alsinoides that are effective as tonics and antipyretics, it has never been used in cosmetics or hair growth agents.
本発明で用いる低級アルキルアルコールとは、メタノー
ル、エタノール、プロパツールなどであ−る。The lower alkyl alcohol used in the present invention includes methanol, ethanol, propatool, and the like.
次に、本発明に係わる育毛・発毛促進成分を得る方法の
事例を示す。Next, an example of a method for obtaining a hair growth/hair growth promoting ingredient according to the present invention will be shown.
アサガオカラクサ５０ｇをエタノール１リツトルで４時
間ずつ３回温浸抽出する。これら抽出物を合わせ、吸引
濾過後、溶媒を除くために減圧上濃縮乾固し、本発明に
係わる粘稠状の抽出物を得る。50g of Morning Glory is digested and extracted with 1 liter of ethanol three times for 4 hours each. These extracts are combined, filtered with suction, and then concentrated to dryness under reduced pressure to remove the solvent to obtain a viscous extract according to the present invention.
本発明の育毛−発毛料の育毛・発毛促進成分として含有
されるアサガオカラクサの抽出物の含有量は全量の０．
００１〜１０重量％、好ましくは０．０５〜５重量％で
ある。含有濃度が０．００１重量％より低濃度では下記
に示すマウスを用いた育毛試験において十分な育毛効果
を示さず、また１０重量％より高濃度では育毛・発毛料
としての安定性が十分でない。The content of extract of Morning Glory, which is contained as a hair growth/hair growth promoting ingredient in the hair growth/hair growth agent of the present invention, is 0.00% of the total amount.
001 to 10% by weight, preferably 0.05 to 5% by weight. If the concentration is lower than 0.001% by weight, sufficient hair growth effect will not be shown in the hair growth test using mice shown below, and if the concentration is higher than 10% by weight, the stability as a hair growth agent will not be sufficient.
本発明の育毛・発毛料で使用される他の原料成分として
は、通常、育毛・発毛料に適用される炭化水素類、ロウ
類、油脂類、エステル類、高級脂肪酸類、高級アルコー
ル類、界面活性剤、香料、色素、防腐剤、抗酸化剤、紫
外線防御剤、アルコール類、ｐＨ調整剤、および本発明
の目的にあった薬効成分などが適宜選択され、調製され
る。Other raw materials used in the hair growth/growth agent of the present invention include hydrocarbons, waxes, fats and oils, esters, higher fatty acids, higher alcohols, and interfaces that are usually applied to hair growth/growth agents. Activators, fragrances, pigments, preservatives, antioxidants, UV protection agents, alcohols, pH adjusters, medicinal ingredients suitable for the purpose of the present invention, and the like are appropriately selected and prepared.
また、本発明の発毛・育毛料としては、種種の様態たと
えばクリーム、ヘアトニック、ヘアローション、ヘアク
リームなどがあげられる。Further, the hair growth/hair growth agent of the present invention may be in various forms such as cream, hair tonic, hair lotion, hair cream, etc.
くマウスを用いた育毛試験〉
（検 体）
本発明に適用されるアサガオカラクサよりの抽出物を０
．５重量％含有した無水エタノール溶液及び従来から育
毛・発毛促進成分として知られているビタミンＥを０．
５重量％含有した無水エタノール溶液、並びにコントロ
ールとしてのエタノール及び水の４検体。Hair growth test using mice
．． Anhydrous ethanol solution containing 5% by weight and 0.0% vitamin E, which is conventionally known as a hair growth promoting ingredient.
Absolute ethanol solution containing 5% by weight, and 4 samples of ethanol and water as controls.
（育毛試験法）
９週令のＣ３Ｈマウスを用いて、１群を１０匹とし、４
群作り、これらの背部の２．ＯＸ ２．０ の広さに
除毛した部位に除鳴後翌日検体を０．０２ｇ塗布した後
、５白目、１４日日目当該部位の毛成長の密度を色差計
を用いてＬ値を測定し、Ｌ値の減少を黒色増加度とした
。(Hair growth test method) Using 9-week-old C3H mice, 10 mice per group, 4
Grouping, these dorsal 2. After applying 0.02g of the sample on the area of OX 2.0 on the day after removal of the hair, measure the density of hair growth in the area on the 5th and 14th day using a color difference meter to measure the L value. The decrease in the L value was defined as the degree of increase in black color.
（以下余白）
（結 果）
表１ 黒色増加度
表１より明らかなように、本発明に係わるアサガオカラ
クサよりの抽出物を含有する無水エタノ−ル溶液の方が
色差計のＬ値が小さ（なっており、黒色度が大きくなっ
ていることがわかる。(The following is a blank space) (Results) Table 1 Black increase degree As is clear from Table 1, the anhydrous ethanol solution containing the extract from Morning Glory of the Invention according to the present invention has a smaller L value on the color difference meter ( It can be seen that the degree of blackness has increased.
これは、本発明に係わる抽出物が、毛根を刺激し、毛包
周囲の血行を盛んにし代謝を活発にしたものと推測され
、育毛・発毛促進成分として非常に優れていることを示
すものである。This indicates that the extract according to the present invention stimulates the hair roots, increases blood circulation around the hair follicles, and activates metabolism, indicating that it is an extremely excellent ingredient for promoting hair growth. It is.
以下、実施例と比較例にて本発明を説明する。 The present invention will be explained below with reference to Examples and Comparative Examples.
尚、配合量は重量部である。In addition, the blending amount is in parts by weight.
実施例１． ヘアローシロン
（処 方）
アサガオカラクサ抽出物 ２．５９−メント
ール ０．２エタノール
３２．５ポリオキシエチレン硬化ヒマ
シ油 ０．５精製水 ６
４．３（製 法）
上記処方物を４５°Ｃに加温して十分撹拌し均一に溶解
した後、常温まで冷却して製品とする。Example 1. Hairo Shiron (prescription) Morning glory extract 2.59-menthol 0.2 ethanol
32.5 Polyoxyethylene hydrogenated castor oil 0.5 Purified water 6
4.3 (Manufacturing method) The above formulation is heated to 45°C and sufficiently stirred to dissolve uniformly, and then cooled to room temperature to form a product.
く人による育毛・発毛効果試験〉
（ｉ）発毛効果試験
（試験法）
薄毛症、脱毛症を訴える１９名のパネラ−に実施例−１
に示すヘアローションを連続６ケ月使用させることによ
る発毛効果試験を実施した。使用方法は通常のヘアロー
ジョイ使用法と同様−日２回、頭部にまんべんなく塗布
する方法を用いた。Hair growth/hair growth effect test by people > (i) Hair growth effect test (test method) Example 1 was given to 19 panelists complaining of thinning hair and alopecia.
A hair growth effect test was conducted by using the hair lotion shown in Figure 2 for 6 consecutive months. The method of use was the same as the usual method of using Hair Lojo - apply it evenly to the head twice a day.
評価は使用開始後３ケ月目と６ケ月目に行ない、うぶ毛
、硬毛が増えてきたと感じた対象者がどの程度増えたか
を計測した。Evaluations were conducted 3 months and 6 months after the start of use, and the extent to which the number of subjects who felt that downy hair and terminal hair had increased was measured.
（結 果）
表２ 発毛効果
表２から明らかなように、本発明品は、うぶ毛硬毛を増
やし、発毛効果が認められた。(Results) Table 2 Hair Growth Effect As is clear from Table 2, the product of the present invention increased downy terminal hair, and a hair growth effect was observed.
（ｉｉ）育毛効果試験
前記テスト終了時に白髪の減少を申告したものが４名い
た。(ii) Hair growth effect test At the end of the test, four people reported a decrease in gray hair.
また、頭皮の状態も改善され、ふけの発生の減少を申告
したものが７名いた。In addition, the condition of the scalp improved, and seven people reported a decrease in the occurrence of dandruff.
この結果から本発明品には育毛効果があることが証明さ
れた。This result proved that the product of the present invention has a hair growth effect.
また、この使用テスト期間中に頭皮の状態の悪化、炎症
性の反応等は全（観察されなかった。Furthermore, no deterioration of the scalp condition, inflammatory reactions, etc. were observed during this usage test period.
実施例２． ヘアトニック
（処 方）
アサガオカラクサ抽出物 ２．０メントー
ル ０．２エタノール
６０．０精製水
３７．８（製 法）
エタノールにアサガオカラクサ抽出エキス、メントール
を溶解しておき、精製水を加えて製品とする。Example 2. Hair tonic (prescription) Morning glory extract 2.0 Menthol 0.2 Ethanol
60.0 Purified water
37.8 (Manufacturing method) Dissolve morning glory extract and menthol in ethanol, and add purified water to prepare the product.
Ｑ−
実施例３． ヘアクリーム
（処 方） −
アサガオカラクサ抽出物 １．０ワセリン
７．０ミツロウ
８．０流動パラフイン
３７．０乳化剤
５．０精製水 ４１．５
（製 法）
アサガオカラクサ抽出エキス、ワセリン、ミツロウ、流
動パラフィン、乳化剤を温度調整器付きのホモミキサー
の容器にとり、８０°Ｃにて混合溶解し、あらかじめ８
０℃に加熱しておいた精製水を徐々に加えて乳化する。Q- Example 3. Hair cream (prescription) - Morning glory extract 1.0 Vaseline 7.0 Beeswax
8.0 liquid paraffin
37.0 Emulsifier
5.0 Purified water 41.5
(Manufacturing method) Place morning glory extract, vaseline, beeswax, liquid paraffin, and emulsifier in a homomixer container equipped with a temperature controller, mix and dissolve at 80°C, and mix and dissolve at 80°C in advance.
Gradually add purified water heated to 0°C to emulsify.
常温まで冷却し、製品とする。Cool to room temperature and use as a product.
実施例４． ポマード
（処 方）
アサガオカラクサ抽出物 ３．５イソプロ
ピルミリステート １０．０セタノール
２．０パラフィンロウ
６．０マイクロクリスタリンワツクス
１０．０乳化剤 １０．
０精製水 ５８．５（製
法）
アサガオカラクサ抽出物、イソプロピルミリステート、
セタノール、パラフィンロウ、マイクロクリスタリンワ
ックス、乳化剤を８０″Ｃにて加熱溶解し、あらかじめ
８０℃に加熱しておいた精製水を加えて撹拌する。Example 4. Pomade (formulation) Morning glory extract 3.5 isopropyl myristate 10.0 cetanol
2.0 paraffin wax
6.0 microcrystalline wax
10.0 Emulsifier 10.
0 Purified water 58.5 (manufactured by
method) morning glory extract, isopropyl myristate,
Setanol, paraffin wax, microcrystalline wax, and emulsifier are dissolved by heating at 80"C, and purified water previously heated to 80"C is added and stirred.
４０°Ｃまで撹拌しながら冷却し、製品とする。Cool to 40°C with stirring to obtain a product.
本発明に係わるアサガオカラクサの抽出物には、マウス
の育毛試験において育毛効果が認められた。The extract of Morning Glory according to the present invention was found to have a hair growth effect in a hair growth test on mice.
また、本発明のアサガオカラクサの抽出を配合した育毛
・発毛料には、ヒトを対象とした実使用試験において育
毛・発毛効果が認められた。In addition, the hair growth/hair growth agent containing the morning glory extract of the present invention was found to have hair growth/hair growth effects in practical use tests on humans.
更に、長期連用による皮膚障害が認められなかった。Furthermore, no skin disorders due to long-term use were observed.
Claims (1)
ｎｏｉｄｅｓ：アサガオカラクサ属）を抽出溶媒で抽出
して得られる抽出物を育毛・発毛促進成分として含有す
ることを特徴とする育毛・発毛料。 ２）前記の抽出溶媒が、水または低級アルキルアルコー
ルから選ばれたものである請求項１）記載の育毛・発毛
料。[Claims] 1) Evolvulus alsi
1. A hair growth/hair growth agent characterized by containing an extract obtained by extracting P. noides (genus Morning Glory) with an extraction solvent as a hair growth/promoting ingredient. 2) The hair growth agent according to claim 1, wherein the extraction solvent is selected from water or lower alkyl alcohol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2332728A JP2801962B2 (en) | 1990-11-29 | 1990-11-29 | Hair growth and hair growth |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2332728A JP2801962B2 (en) | 1990-11-29 | 1990-11-29 | Hair growth and hair growth |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH04202116A true JPH04202116A (en) | 1992-07-22 |
| JP2801962B2 JP2801962B2 (en) | 1998-09-21 |
Family
ID=18258202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2332728A Expired - Lifetime JP2801962B2 (en) | 1990-11-29 | 1990-11-29 | Hair growth and hair growth |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2801962B2 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001181171A (en) * | 1999-12-27 | 2001-07-03 | Pola Chem Ind Inc | Cosmetic |
| JP2003221314A (en) * | 2002-01-25 | 2003-08-05 | Kunio Tsuji | Skin care preparation for external use to be used for hair growth |
| JP2003221313A (en) * | 2002-01-25 | 2003-08-05 | Kunio Tsuji | Skin care preparation for external use for hair growth comprising crude drug extracts having body-fluid action and vascularization action |
-
1990
- 1990-11-29 JP JP2332728A patent/JP2801962B2/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001181171A (en) * | 1999-12-27 | 2001-07-03 | Pola Chem Ind Inc | Cosmetic |
| JP2003221314A (en) * | 2002-01-25 | 2003-08-05 | Kunio Tsuji | Skin care preparation for external use to be used for hair growth |
| JP2003221313A (en) * | 2002-01-25 | 2003-08-05 | Kunio Tsuji | Skin care preparation for external use for hair growth comprising crude drug extracts having body-fluid action and vascularization action |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2801962B2 (en) | 1998-09-21 |
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