JPS61207321A - Hair tonic - Google Patents

Hair tonic

Info

Publication number
JPS61207321A
JPS61207321A JP4835385A JP4835385A JPS61207321A JP S61207321 A JPS61207321 A JP S61207321A JP 4835385 A JP4835385 A JP 4835385A JP 4835385 A JP4835385 A JP 4835385A JP S61207321 A JPS61207321 A JP S61207321A
Authority
JP
Japan
Prior art keywords
hair
higher aliphatic
hair tonic
effect
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4835385A
Other languages
Japanese (ja)
Inventor
Mizuo Yajima
瑞夫 矢嶋
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asama Chemical Co Ltd
Original Assignee
Asama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asama Chemical Co Ltd filed Critical Asama Chemical Co Ltd
Priority to JP4835385A priority Critical patent/JPS61207321A/en
Publication of JPS61207321A publication Critical patent/JPS61207321A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

PURPOSE:To provide a hair-grower containing a specific higher aliphatic alcohol. CONSTITUTION:A hair tonic having excellent effect compared with conventional hair tonics and absolutely free from hormonic action is obtained by compounding a 22-36C higher aliphatic monohydric alcohol (e.g.docosanol, tetracosanol, hexacosanol, octacosanol, etc.). The above higher aliphatic monohydric alcohol may be the one produced by chemical synthesis or the one extracted from a natural source (e.g. alfalfa, skin of apple, skin of grape, sugar cane, etc.: existing in extremely small amount mainly in vegetable wax). The hair tonic can be used in various bases (e.g. milky lotion, cream, lotion, etc.) and used also in combination of other components having hair tonic effect.

Description

【発明の詳細な説明】 本発明は養毛料に関する。[Detailed description of the invention] The present invention relates to a hair nourishing agent.

従来より各種の薬効成分を配合した養毛料が知られてい
る。例えばビタミンEなどのビタミン類、セリン、メチ
オニンなどのアミノ酸類、アセチルコリン誘導体などの
血管拡張剤。
BACKGROUND ART Hair tonics containing various medicinal ingredients have been known for some time. For example, vitamins such as vitamin E, amino acids such as serine and methionine, and vasodilators such as acetylcholine derivatives.

架板エキス等の抗炎症剤、などが配合された養毛料が公
知であるが、真に養毛効果があるものはなく、十分満足
できるものではない。
Although hair nourishing agents containing anti-inflammatory agents such as veneer extract are known, none of them truly have a hair nourishing effect and are not fully satisfactory.

また男性型の禿頭や脂漏などの生理学上の徴候な男性ホ
ルモンの過剰蓄積に基づく男性ホルモン刺激の増大によ
ることが知られ、それを防止するため1女性ホルモンが
使用されている。しかしながら副作用として全身的に作
用し、男性の女性化など好ましくないホルモン作用を有
しているという欠点があった。
It is also known that male pattern baldness and seborrhea are caused by increased stimulation of male hormones due to excessive accumulation of male hormones, and female hormones are used to prevent this. However, it has the disadvantage that it acts systemically as a side effect and has undesirable hormonal effects such as feminization of men.

本発明者は、上記の事情に鑑み、ホルモン作用を有せず
、安全で養毛効果のすぐれた養毛料を得るべく、鋭意研
究の結果、炭素数22〜あの高級脂肪族−価アルコール
を配合することにより、上記の目的を達成できることを
見出し2本発明に至った。すなわち本発明は炭素数22
〜34個の高級脂肪族−価アルコールを配合してなる養
毛料で、ホルモン作用は全く有せず、かつ従来の養毛料
よりもすぐれた効果を有する養毛料を提供するものであ
る。
In view of the above circumstances, the inventor of the present invention, as a result of intensive research, has formulated a higher aliphatic alcohol with a carbon number of 22 or more in order to obtain a hair nourishing agent that does not have hormonal effects, is safe, and has an excellent hair nourishing effect. The inventors have found that the above object can be achieved by doing so, and have arrived at the present invention. That is, the present invention has 22 carbon atoms.
This hair care product is a hair care product containing ~34 higher aliphatic alcohols, has no hormonal action, and has a superior effect to conventional hair care products.

以下本発明の構成について詳述する。The configuration of the present invention will be explained in detail below.

本発明で用いられる炭素数22〜36の高級脂肪族−価
アルコールとして、ドフサノール(C22H4,0)、
テトラコサノール(C24H480)。
As the higher aliphatic alcohol having 22 to 36 carbon atoms used in the present invention, dofusanol (C22H4,0),
Tetracosanol (C24H480).

ヘキサコサノール(C211H5□0)、オクタコサノ
ール(c2sH,60)、 トリアフンタノール(C3
0H6oO)。
Hexacosanol (C211H5□0), octacosanol (c2sH,60), triafuntanol (C3
0H6oO).

ドトリアコンタノール(C3□h<o)、テトラ、トリ
7コンタノール(C34H6110)などをあげること
ができる。これらの高級脂肪族−価アルコールの中では
、特にドコサノールCC22H45O)が好ましい。こ
れらの高級脂肪族−価アルコールは。
Examples include dotriacontanol (C3□h<o), tetracontanol, and tri7contanol (C34H6110). Among these higher aliphatic alcohols, docosanol (CC22H45O) is particularly preferred. These higher aliphatic alcohols.

化学合成で得られたものでも良いし、あるいは天然から
抽出したものでもよい。これらの天然脂肪族−価アルコ
ールは、天然中にはアルファルファ、リンゴの果皮、ブ
ドウの果皮。
It may be obtained by chemical synthesis or may be extracted from nature. These natural aliphatic alcohols are found naturally in alfalfa, apple skin, and grape skin.

砂糖キビ等、植物ワックスを中心として極微1含まれて
おり、天然可食物質である。
It is a natural edible substance that contains microscopic amounts of plant waxes such as sugar cane.

本発明に係る養毛料は種々のタイプの基剤。The hair nourishment according to the present invention includes various types of bases.

たとえば乳液、クリーム5 ローシ冒ンなどの種々のタ
イプにおいて使用することができる。
For example, it can be used in various types such as emulsion, cream 5, and lotion.

もちろん他の養毛効果を有する成分と併用することもで
きる。
Of course, it can also be used in combination with other ingredients that have a hair-nourishing effect.

実施例1.比較例 (製造法) 実施例1の養毛料:第1表に示す処方で製造した。まず
95%エタノールに硬化ヒマシ、油(EO)40モル付
加物と第2表に示す組成を有する高級脂肪族−価アルコ
ールを添加し、加温して溶解した後、攪拌しながら交換
水を添加して懸濁液とした。
Example 1. Comparative Example (Manufacturing Method) Hair nourishing agent of Example 1: Manufactured according to the formulation shown in Table 1. First, hydrogenated castor, a 40 mol adduct of oil (EO), and a higher aliphatic alcohol having the composition shown in Table 2 are added to 95% ethanol, and after heating and dissolving, exchange water is added while stirring. A suspension was obtained.

比較例の養毛料:実施例1の養毛料に準じ゛ て製造し
′た。ただし、高級脂肪族−価アル−コールが添加され
ていないので、透明液状となる。
Comparative hair nourishing agent: Manufactured in accordance with the hair nourishing agent of Example 1. However, since no higher aliphatic alcohol is added, it becomes a transparent liquid.

第1表 (重量ラノ 実施例1  比較例 高級脂肪族−価71レコール   0.5−95% エ
タノール  6060 硬化ヒマシ油(EO)40モル     22付加物 イオン交換水 37.5 38.0 第2表 (養毛効果試験法) 養毛料使用前後の洗髪時脱毛、本数の変、化で養毛効果
を判定した。
Table 1 (Weight Rano Example 1 Comparative example Higher aliphatic value 71 Recol 0.5-95% Ethanol 6060 Hydrogenated castor oil (EO) 40 mol 22 Adduct Ion exchanged water 37.5 38.0 Table 2 ( Hair nourishing effect test method) The hair nourishing effect was determined by the amount of hair removed during hair washing before and after using the hair nourishing agent, and the change in the number of strands.

被験者は、実施例1および比較例の各々の群ごとに10
名とした。測定期間は、4ケ月間とし、最初の2ケ月間
は養毛料無塗布の期間とし、この間、2日おきに洗髪し
1週間に1変波毛を回収しその本数を数えた。各期間の
抜毛本数の表示は、養毛料無塗布の2ケ月間、計8回の
抜毛本数のデータと養毛料塗布の2ケ月間、計8回の抜
毛本数のデータをそれぞれの期間ごとにまとめ、平均値
上a(イ)の型で1回当りの抜毛本数として表示した。
Subjects were tested 10 times in each group of Example 1 and Comparative Example.
The name was given. The measurement period was 4 months, and the first 2 months were a period in which no hair tonic was applied.During this period, the hair was washed every 2 days, and one variable wave hair was collected per week and the number of hairs was counted. The number of hairs pulled out for each period is summarized for each period, data on the number of hairs pulled out 8 times in total for 2 months without hair growth agent application, and data on the number of hairs pulled out 8 times in total for 2 months with hair growth agent applied. , the average value was expressed as the number of hairs pulled per session in the form of A (A).

養毛効果の判定は。How to judge the hair growth effect.

養毛料無塗布期間の平均値の差から次のように表示した
The difference in the average value of the period without application of hair tonic was expressed as follows.

一二抜毛木数の減少が10本未満であり効果ありとはい
えない。
The reduction in the number of hairs pulled was less than 10, so it cannot be said to be effective.

±:抜毛木数が10本以上減りておつ やや効果が認められた。±: The number of hairs removed has decreased by 10 or more. A slight effect was observed.

十二抜毛木数が40本以上減っており かなりの効果が認められた。The number of twelve-haired trees has decreased by more than 40. A considerable effect was observed.

+:抜毛木数が70本以上減っており 著しい効果を認めた。+: The number of hair-pulled trees has decreased by more than 70. A significant effect was observed.

(結果) 第3表 第3表から明らかのように1本発明である実施例1の養
毛材は、対照区(比較例)に比べて、著しい養毛効果を
有することがわかる。
(Results) As is clear from Table 3, the hair nourishing material of Example 1, which is the present invention, has a remarkable hair nourishing effect compared to the control group (comparative example).

実施例2.(ローションタイプ養毛材)下記の処方でロ
ーシコンタイプの養毛材を製造した。
Example 2. (Lotion type hair nourishing material) A lotion type hair nourishing material was manufactured using the following formulation.

95%エタノール          60%(重量)
イオン交換水     37 硬化ヒマシ油(Eo) 40モル付加物     2製
造方法は、実施例1と同じ方法で行った。
95% ethanol 60% (weight)
Ion exchange water 37 Hydrogenated castor oil (Eo) 40 mol adduct 2 The manufacturing method was the same as in Example 1.

また養毛効果も実施例1と同じように認められた。In addition, the same hair growth effect as in Example 1 was observed.

実施例3.(クリームタイプ養毛材) 下記の処方でクリームタイプ養毛材を製造した。Example 3. (Cream type hair nourishing material) A cream type hair nourishing material was manufactured using the following formulation.

% ^ 流動パラフィン      38.5(重量)ステ
アリン酸       2 白ワセリン       10 ビタミンEニコチネート       0.1フルビタ
ンモノステアレート      4.2エチルパラベン
         微 量(81トリエタノールアミン
        lポリエチレングリコール1500 
    2イオン交換水        37.9香 
  料             適 量上記油相(2
)、水相(81とそれぞれ85″′Cに加熱し、同温度
で同成分を攪拌しながら混合乳化し、常温まで冷却し、
養毛材を得た。養毛効果は、実施例1と同様に著しい効
果が認められた。
% ^ Liquid paraffin 38.5 (weight) Stearic acid 2 White petrolatum 10 Vitamin E Nicotinate 0.1 Fulvitan monostearate 4.2 Ethylparaben Trace amount (81 Triethanolamine l Polyethylene glycol 1500
2 ion exchange water 37.9 fragrance
Appropriate amount of the above oil phase (2
), aqueous phase (81 and 85''C respectively, mixed and emulsified with stirring the same components at the same temperature, cooled to room temperature,
I got hair nourishing material. Similar to Example 1, a remarkable hair growth effect was observed.

実施例4、(乳液タイプ養毛材す 下記の処方で乳液タイプ養毛材を製造した。Example 4 (Emulsion type hair nourishing material) An emulsion type hair nourishing material was manufactured using the following formulation.

(2)精製ホホバ油      10%ニコチン酸ベン
ジル     2 ラ  ノ   リ  ン              
         2イソプロピルミリステート2.5 ポリオ牛ジエチレンセチルアルコール    1.8ソ
ルビタンモノステアレート          0.8
エチルパラベン           微量U3)トリ
エタノールアミン        1グリセリン   
  4 イオン交換水    75.4 香    料            適 量実施例3
と同じ方法で製造した。
(2) Refined jojoba oil 10% benzyl nicotinate 2 lanolin
2 Isopropyl myristate 2.5 Polio bovine diethylene cetyl alcohol 1.8 Sorbitan monostearate 0.8
Ethylparaben Trace amount U3) Triethanolamine 1 Glycerin
4 Ion-exchanged water 75.4 Fragrance Appropriate amount Example 3
manufactured in the same manner as.

養毛効果は実施例1と同様のすぐれた効果が認められた
As for the hair growth effect, the same excellent effect as in Example 1 was observed.

Claims (1)

【特許請求の範囲】[Claims] 炭素数22〜34の高級脂肪族アルコールを含有するこ
とを特徴とする発毛料
A hair growth agent characterized by containing a higher aliphatic alcohol having 22 to 34 carbon atoms.
JP4835385A 1985-03-13 1985-03-13 Hair tonic Pending JPS61207321A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4835385A JPS61207321A (en) 1985-03-13 1985-03-13 Hair tonic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4835385A JPS61207321A (en) 1985-03-13 1985-03-13 Hair tonic

Publications (1)

Publication Number Publication Date
JPS61207321A true JPS61207321A (en) 1986-09-13

Family

ID=12801003

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4835385A Pending JPS61207321A (en) 1985-03-13 1985-03-13 Hair tonic

Country Status (1)

Country Link
JP (1) JPS61207321A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0488928A2 (en) * 1990-11-30 1992-06-03 Centro Nacional De Investigaciones Cientificas Pharmaceutical formulations containing a mixture of higher primary aliphatic alcohols in the treatment of hypercholesterolaemia and hyperlypoproteinaemia type II and stimulation of sexual behavior in animals and humans
GR910100346A (en) * 1990-08-16 1992-08-31 Colgate Palmolive Co Stabilized liquid fiber and skin treating compositions
US5236950A (en) * 1988-02-18 1993-08-17 Toyama Chemical Co., Ltd. Process for hair growth
US5587174A (en) * 1992-02-28 1996-12-24 Wella Aktiengsellschaft Cosmetic composition for treating skin and hair containing apple wax and methods of making them
EP0813859A3 (en) * 1996-06-22 1998-09-09 Wella Aktiengesellschaft Hair care sustained release composition
EP1314417A4 (en) * 2000-08-31 2004-09-22 Shiseido Co Ltd Hair growers

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236950A (en) * 1988-02-18 1993-08-17 Toyama Chemical Co., Ltd. Process for hair growth
GR910100346A (en) * 1990-08-16 1992-08-31 Colgate Palmolive Co Stabilized liquid fiber and skin treating compositions
JPH04244009A (en) * 1990-08-16 1992-09-01 Colgate Palmolive Co Composition for treating hair, fiber and skin
EP0488928A2 (en) * 1990-11-30 1992-06-03 Centro Nacional De Investigaciones Cientificas Pharmaceutical formulations containing a mixture of higher primary aliphatic alcohols in the treatment of hypercholesterolaemia and hyperlypoproteinaemia type II and stimulation of sexual behavior in animals and humans
US5587174A (en) * 1992-02-28 1996-12-24 Wella Aktiengsellschaft Cosmetic composition for treating skin and hair containing apple wax and methods of making them
EP0813859A3 (en) * 1996-06-22 1998-09-09 Wella Aktiengesellschaft Hair care sustained release composition
EP1314417A4 (en) * 2000-08-31 2004-09-22 Shiseido Co Ltd Hair growers

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