JPS6041046B2 - Anti-dandruff hair cosmetics - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an anti-dandruff hair cosmetic containing vitamin E acetate and pantothenylethyl ether.

In general, dandruff consists of secretions from sebaceous glands, secretions from sweat glands, detachment from the surface cortex, etc., and is usually caused by redness of sebaceous glands, but when the skin is infected with bacteria or yeast, It is said that the development of dandruff is pathologically promoted. For this reason, hair cosmetics containing antibacterial agents have traditionally been used to prevent dandruff. However, some antibacterial agents have safety issues, and cosmetics containing antibacterial agents can disrupt the delicate balance of resident bacteria on the skin when used on a daily basis, sometimes resulting in unfavorable situations from an ecological point of view. Therefore, there is a demand for anti-dandruff cosmetics that do not use antibacterial agents, but so far, Q-tocopherol vitamin A acid ester ( Special Publication No. 51-73137) and vitamin E nicotinic acid ester (German Patent No. 2301)
No. 585 and No. 2301660) have been reported. However, these esters of vitamin E (same as Q tocopherol) have some problems with their safety on the skin, and in addition, they have the disadvantage of being expensive. Therefore, the present inventors searched extensively for substances with anti-dandruff effects among vitamin E derivatives, and found that vitamin E acetate, which has a relatively simple structure, is extremely useful.
Then, they discovered that when this product is combined with pantothenylethyl ether, which does not exhibit an anti-dandruff effect by itself, the anti-dandruff effect can be further enhanced and the amount of vitamin E acetate can be reduced accordingly, and the present invention has been made. I came to do this.

That is, the present invention provides vitamin E acetate (hereinafter "
Also called "VEA".

) and pantothenylethyl ether (hereinafter also referred to as "PEE"). It is preferable to contain VEA in an amount of 0.1% by weight or more and PEE in an amount of 0.01% by weight or more. When the hair cosmetic of the present invention is used, the metabolic reaction within the scalp tissue is appropriately adjusted, and the occurrence of dandruff can be effectively prevented, and the effect is greater than when vitamin E acetate is used alone.

Of course, the product of the present invention is safe for the skin, unlike when antibacterial agents are used. Vitamin E acetate (VEA) in the present invention is a known substance, a sticky amorphous oily substance, and is generally soluble in oils and fats, paraffin, organic solvents, etc. It is insoluble or soluble in organic solvents.

This product can be blended into cosmetics in accordance with the method for blending general oily substances. Pantothenylethyl ether (PEE) is a known substance that is sticky steel, hygroscopic, and soluble in water, alcohol, and the like.

It is preferable that the hair cosmetic of the present invention contains 0.1% by weight or more of VEA and 0.01% by weight or more of PEE.

When using VEA alone, the desired dandruff prevention effect can be achieved at 0.5% by weight or more, preferably 1.0% by weight or more, but depending on the form of the product, if VEA is contained at 1.0% or more, Problems such as oil separation and cloudiness may occur, which may impair the product's shape, or the product may become oily, resulting in problems in usability. Therefore, when we investigated methods to reduce the VEA content, we found that it did not show any dandruff-preventing effect by itself. It was found that when PEE is added to about 1/10 of VEA, VEA is effective in preventing dandruff even at a concentration of 0.1% by weight.

The hair cosmetics of the present invention broadly refer to those applied to the hair or scalp, and include, for example, hair tonics, hair liquids, scalp emulsions, hair creams, hair shampoos, and the like.

The hair cosmetic of the present invention includes VEA, which is the essential ingredient,
In addition to PEE, usual components such as oily components, surfactants, heat insulating agents, alcohols, thickeners, preservatives, ultraviolet absorbers, color filters, fragrances, etc. may be added in appropriate amounts. Test example V
The anti-dandruff effect was investigated by varying the blending amounts of EA and PEE.

Hair tonics having the formulations shown in Table 1 were prepared as samples. Notes to Table 1 VEA: Vitamin Nippon Acetic Acid Ethyl Able PEE: Bantotenyl Ethyl Able 40 men with ages 22 to 367 were randomly selected as subjects, and a total of 40 men, 5 men for each sample, were tested.

The hair tonic was to be used once only after washing the hair, and the amount of dandruff after the start of the test was compared with the amount of dandruff 3 days after washing the hair at the end of the test, and if the amount of dandruff at the end of the test was small, it was considered to have a dandruff suppressing effect. If the amount of dandruff did not change or if it increased, it was determined that there was no dandruff suppressing effect. The head was suctioned using a vacuum cleaner, and the weight of the collected dandruff was measured to obtain the test results shown in Table 2. Table 2 A hair tonic containing 0.1% vitamin E acetate (sample 1) showed no dandruff suppressing effect on 5 subjects, but it also contained 0.01% pantothenylethyl ether.
% added hair tonic (sample 3) showed dandruff suppressing effects in 4 out of 5 subjects.

In the case of hair tonic containing 0.5% vitamin E acetate (sample 5), dandruff suppressing effects were observed in 3 out of 5 subjects, but when 0.0% pantothenylethyl ether was added
When 5% was added (sample 6), the dandruff suppressing effect was recognized by all subjects.

None of the subjects who used the hair tonic containing 0.1% pantothenylethyl ether (Sample 8) showed any effect on suppressing fleas. Next, examples of the present invention will be shown. Example 1 55% ethyl alcohol, 0% vitamin E acetate.
1 night, pantothenyl ethyl ether 0.01 night, polyoxyethylene (8 mol) oleyl alcohol ether 2
Appropriate amounts of alcohol and fragrance were dissolved at room temperature to obtain an alcohol phase.

Separately, an appropriate amount of purified water, 37.89 g of glycerin, and a pigment were dissolved at room temperature, and the alcohol phase was added to the aqueous phase to obtain a hair tonic. Example 2 Ethyl alcohol 54.89 hours, vitamin E acetate 0.1 night, pantothenyl ethyl ether 0.01 night,
An appropriate amount of purified water containing a pigment was added to an alcohol phase in which 20 days of polyoxypropylene butyl ether and an appropriate amount of fragrance were dissolved at room temperature, and the mixture was mixed to obtain a hair liquid.

Example 3 Stearic acid 2 nights, cetyl alcohol 1.5 nights, vaseline 3 nights, liquid paraffin 12 nights, polyoxyethylene (
10 moles) Monooleic acid ester 2 times, Vitamin E acetate 0.1 time, Pantothenylethyl ether 0.
Appropriate amounts of 100g and fragrance were added and heated to 80°C to obtain an oil phase.

Separately, 5 nights of propylene glycol, 1 night of triethanolamine, and 73.39 nights of purified water were heated to 80°C to obtain an aqueous phase. The oil phase was gradually added to the aqueous phase while stirring, emulsified, and cooled to obtain a scalp emulsion. Example 4 2 parts of stearic acid, 7 parts of stearyl alcohol, 2 parts of reduced lanolin, 5 parts of squalane, 6 parts of octyldodecanol
Evening, polyoxyethylene (10 mol) cetyl ether 3
evening, glyceryl monostearate 2 evenings, vitamin E acetate 0.1 evening, pantothenylethyl ether 0.0 evening
After one night, an appropriate amount of fragrance was added and heated to 80°C to obtain an oil phase.

Separately, to an aqueous phase obtained by heating propylene glycol 59 and purified water 67.89 to 8000, the oil phase was gradually added while stirring, emulsified, and cooled to obtain a hair cream. Example 5 Purified water: 79.89% Triethanolamine lauryl sulfate: 15%, Coconut oil fatty acid monoethanolamide: 5%
Then, 0.1 g of vitamin E acetate, 0.01 g of pantothenylethyl ether, and appropriate amounts of pigments and fragrances were added, and after heating and mixing, the mixture was cooled to obtain a hair shampoo.

Claims (1)

[Scope of Claims] 1. A hair cosmetic containing vitamin E acetate and pantothenyl ethyl ether. 2. The hair cosmetic according to claim 1, which contains 0.1% by weight or more of vitamin E acetate and 0.01% by weight or more of pantothenyl ethyl ether.