JPH0338276B2 - - Google Patents

Info

Publication number
JPH0338276B2
JPH0338276B2 JP27204285A JP27204285A JPH0338276B2 JP H0338276 B2 JPH0338276 B2 JP H0338276B2 JP 27204285 A JP27204285 A JP 27204285A JP 27204285 A JP27204285 A JP 27204285A JP H0338276 B2 JPH0338276 B2 JP H0338276B2
Authority
JP
Japan
Prior art keywords
substance
streptomyces
strain
culture
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP27204285A
Other languages
English (en)
Japanese (ja)
Other versions
JPS61148181A (ja
Inventor
Masakuni Okuhara
Hirokazu Tanaka
Toshio Goto
Tooru Kino
Hiroshi Hatanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS61148181A publication Critical patent/JPS61148181A/ja
Publication of JPH0338276B2 publication Critical patent/JPH0338276B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP27204285A 1984-12-03 1985-12-03 Ｆｒ―９００５０６物質およびその製造法 Granted JPS61148181A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB848430455A GB8430455D0 (en) 1984-12-03 1984-12-03 Fr-900506 substance
GB8430455 1984-12-03
GB8502869 1985-02-05
GB8508420 1985-04-01

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2204518A Division JPH0372483A (ja) 1984-12-03 1990-07-31 免疫抑制剤
JP2204519A Division JPH0720970B2 (ja) 1984-12-03 1990-07-31 トリシクロ化合物

Publications (2)

Publication Number Publication Date
JPS61148181A JPS61148181A (ja) 1986-07-05
JPH0338276B2 true JPH0338276B2 (enExample) 1991-06-10

Family

ID=10570610

Family Applications (1)

Application Number Title Priority Date Filing Date
JP27204285A Granted JPS61148181A (ja) 1984-12-03 1985-12-03 Ｆｒ―９００５０６物質およびその製造法

Country Status (3)

Country Link
JP (1) JPS61148181A (enExample)
GB (1) GB8430455D0 (enExample)
ZA (1) ZA858867B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007020853A1 (ja) 2005-08-12 2007-02-22 Astellas Pharma Inc. 薬剤の標的蛋白質を同定する方法及び標的蛋白質を用いた糖尿病治療薬のスクリーニング方法
WO2014007362A1 (ja) 2012-07-06 2014-01-09 合同酒精株式会社 環状マクロライド系化合物の分離方法

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
JP2822389B2 (ja) * 1987-06-05 1998-11-11 藤沢薬品工業株式会社 抗ｆｒ−９００５０６物質抗体、および高感度酵素免疫測定法
EP0323865A1 (en) * 1988-01-07 1989-07-12 Merck & Co. Inc. Novel immunosuppressant agent
BR8907766A (pt) * 1988-11-21 1991-08-27 Du Pont Processo para a interconversao de duas formas cristalinas distintas de uma piridina sulfonamida herbicida
AU635286B2 (en) * 1989-07-05 1993-03-18 Astellas Pharma Inc. Aqueous liquid composition for external use
IE904050A1 (en) * 1989-11-13 1991-05-22 Merck & Co Inc Aminomacrolides and derivatives having immunosuppressive¹activity
KR0177158B1 (ko) * 1990-03-01 1999-03-20 후지사와 도모기찌로 면역억제 활성을 갖는 트리사이클릭 화합물 함유 용액 제제
US5260301A (en) * 1990-03-01 1993-11-09 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical solution containing FK-506
IE65341B1 (en) * 1990-11-08 1995-10-18 Fujisawa Pharmaceutical Co Suspensions containing tricyclic compounds
US5250678A (en) * 1991-05-13 1993-10-05 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
KR100253492B1 (ko) * 1991-10-31 2000-05-01 후지야마 아키라 트리사이클로화합물함유 리포솜제제(liposome preparation containing tricyclic compound)
EP0647625A1 (en) * 1992-06-23 1995-04-12 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Novel antibiotics with immunosuppressive activity, delaminomycins, and production thereof
CA2138129A1 (en) * 1992-06-24 1994-01-06 Masato Satoh Novel benzodiazepine derivative
ATE183083T1 (de) * 1992-11-18 1999-08-15 Fujisawa Pharmaceutical Co Pharmazeutische zubereitung mit verlängerter wirkung
JPH06345646A (ja) * 1993-06-08 1994-12-20 Fujisawa Pharmaceut Co Ltd ローション剤
EP0978288A4 (en) * 1997-04-11 2006-07-12 Astellas Pharma Inc DRUG COMPOSITION
GB0012383D0 (en) * 2000-05-22 2000-07-12 Novartis Ag Organic compounds
ITMI20042098A1 (it) * 2004-11-03 2005-02-03 Antibioticos Spa Processo per la purificazione di tacrolimus
MX2007006119A (es) * 2005-01-05 2007-07-19 Teva Gyogyszergyar Zartkoruen Tacrolimus amorfo y preparacion de el.
ITMI20051549A1 (it) * 2005-08-05 2007-02-06 Antibioticos Spa Purificazione del tacrolimus su supporti dimorigine vegetale
JPWO2008026781A1 (ja) 2006-08-31 2010-01-21 直人 奥 逆標的化脂質小胞体
TW200932240A (en) 2007-10-25 2009-08-01 Astellas Pharma Inc Pharmaceutical composition containing lipophilic substance which inhibits IL-2 production
CN102176913B (zh) 2008-10-08 2014-08-13 高田制药株式会社 外用的他克莫司制剂

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007020853A1 (ja) 2005-08-12 2007-02-22 Astellas Pharma Inc. 薬剤の標的蛋白質を同定する方法及び標的蛋白質を用いた糖尿病治療薬のスクリーニング方法
EP2124062A1 (en) 2005-08-12 2009-11-25 Astellas Pharma Inc. Method for identifying target protein of drug and method for screening therapeutic agent for diabetes using the target protein.
WO2014007362A1 (ja) 2012-07-06 2014-01-09 合同酒精株式会社 環状マクロライド系化合物の分離方法

Also Published As

Publication number Publication date
ZA858867B (en) 1986-09-24
JPS61148181A (ja) 1986-07-05
GB8430455D0 (en) 1985-01-09

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