JPH0256409A - Cosmetic containing bi-and trivalent iron salt blended therein - Google Patents

Abstract

PURPOSE:To obtain a cosmetic, usable even for rough, sensitive skin, etc., without anxiety and capable of recovering physiological function, such as phylactic, respiratory, excretory or secretory function, of the skin into a normal state by blending a specific bi-and trivalent iron salt with other ingredients. CONSTITUTION:A cosmetic containing a bi- and trivalent iron salt including a carrier in an amount of 10<-9> to 10<-12>g based on 100g cosmetic base. Although the bi- and trivalent iron salt includes chlorides, sulfates, acetates, etc., of iron capable of exhibiting intermediate properties of bivalent iron salts and trivalent iron salts, a compound expressed by the formula Fe2Cl5.XH2O is most preferred. When the bi-and trivalent iron salt is dissolved in water or inuncted on a hydrous surface, such as skin surface, normal metabolic function, such as promotion of skin function, enhancing regeneration ability, strengthening of resistance to irritants due to environmental pollution, etc., prevention of microbial contamination, prevention of toxic ionic reaction, etc., essential to the skin can be carried out. The cosmetic can be applied to nearly all the cosmetics, such as basic, hairdressing and makeup cosmetics.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to cosmetics containing divalent and trivalent iron salts that have extremely biologically interesting effects such as biologically active effects, ionization suppressing effects, and antiseptic effects. It is.

[Conventional technology]

According to the Pharmaceutical Affairs Law, cosmetics are defined as ``cosmetics that are applied by rubbing, spraying, or similar methods on the human body to cleanse, beautify, increase attractiveness, change appearance, or maintain healthy skin or hair. The product is intended to be used to naturally or artificially improve the appearance of the skin and hair, and is defined as having a mild effect on the human body. For this purpose, a wide variety of products are commercially available, such as lotions, milk creams, shampoos, conditioners, hair tonics, lipsticks, and foundation soaps. In addition, various moisturizers are used to clarify the effects of each cosmetic product.

Natural products such as oil and fat components, surfactants, fragrances, and pigments.

Synthetic raw materials are used, and the O effect has been obtained to some extent depending on each compounded ingredient.

However, due to recent environmental pollution and the accumulation of social stress, the natural physiological functions of the skin have deteriorated, resulting in problematic skin such as rough, dry, and sensitive skin, as well as hair abnormalities such as hair loss and graying. It's booming. If conventional cosmetics are used in such a condition, the physiological functions of the skin will further deteriorate, and the number of problems caused by cosmetics has increased significantly.

[The problem that the invention attempts to solve]

In view of these aspects of cosmetics, there is a desire to develop cosmetics that can restore the skin's natural physiological functions while also fully satisfying the definition of cosmetics set forth by the above-mentioned Pharmaceutical Affairs Pope. To solve this problem, it is rarely possible to solve this problem by relying solely on the direct effects of the individual ingredients of cosmetics, which have been studied to date.

For example, moisturizers such as hyaluronic acid and water-soluble proteins to replenish moisture to dry skin, or vitamin C derivatives for spot removal and whitening, can achieve some desired effect, but in reality, However, there are still various problems with K, such as the durability of its effects and skin irritation due to deterioration of the ingredients after application, and K has not been able to improve the effect of restoring the skin's natural physiological functions. .

[Means to solve the problem]

In view of the above-mentioned circumstances, the present inventor has discovered that it can be used safely on troubled skin such as rough skin and sensitive skin, and that it can also be used to maintain normal physiological functions such as the skin's natural defense functions, respiratory function, and excretory and secretory functions. He has conducted extensive research on cosmetics that can help restore the body's health. As a result, only cosmetics containing specific divalent and trivalent iron salts have the efficacy and effectiveness of conventional cosmetics.
In addition, conventional cosmetics have the ability to improve skin function, enhance regenerative ability, strengthen resistance to irritants caused by environmental pollution, prevent microbial contamination, and inhibit harmful ionic reactions, which are impossible to achieve with conventional cosmetics. It has been found that it is possible to perform normal functions of the body.

That is, the present invention relates to a cosmetic trap characterized by containing a divalent and trivalent iron salt having the above-mentioned purpose.

The present invention will be explained in detail below.

The divalent and trivalent iron salt used in the cosmetics of the present invention is an iron hydrochloride that exhibits intermediate properties between divalent iron salts and divalent iron salts.

inorganic salts such as sulfates, phosphates, nitrates and formates;
There are organic salts such as acetate and propionate. For example, the known ones are F・8C4□・XH2O, F@5
Examples include complex salts of =valent iron and trivalent iron such as CJ8'' F@2C described in No. 60-186581
Examples include J, .XH, and O.

When these divalent iron salts are dissolved in water or rubbed on water-containing surfaces such as the skin surface, they suppress various ionic reactions. It is thought to induce a reaction, and by applying the cosmetics containing iron salts of the present invention, the normal non-ionic reaction system in the body can be restored and the body can be returned to its normal state. .

When blending the above divalent and trivalent iron salts into cosmetics, depending on the properties of the cosmetic, the type of compounding agent, and the intended effect, it is not advisable to blend the divalent and trivalent iron salts alone, but rather, for example, Sodium chloride, sodium sulfate, ammonium chloride, ammonium sulfate, magnesium chloride, diatomaceous earth, bentonite,
Inorganic substances such as silica and alumina, and vegetable fibers,
pulp.

It is most preferable to use organic substances such as vitamins, hormones, proteins, and lipids as carriers to support the divalent and trivalent iron salts.

Cosmetics &ll5 including the carrier with 4% divalent iron salt
al 00 gJ>1(r'-xr"gT6Js
Preferably, t L (F110' to 1r''g) is in the range. Whether the amount added is greater or less than this range, the effect of the divalent and trivalent iron salt is attenuated.

Cosmetics to which the present invention can be applied by incorporating divalent and trivalent iron salts include basic cosmetics such as lotions, milky lotions, creams, and para-cosmetic oils, hair cosmetics such as shampoos, hair tonics, and hair growth agents; lipstick.

It can be applied to almost all cosmetics, such as foundation cosmetics and makeup cosmetics such as blusher. However, it is necessary to select and use water-soluble or water-dispersible carriers, oil-dispersible carriers, and powder carriers in consideration of the shape and uniform dispersibility of the cosmetic product.

The pH of the cosmetics used can range from 8 to 11, but the most preferred PR range is pH 5 to 8.

The cosmetics of the present invention include solvents, oils and fats, surfactants, and preservatives that are commonly used in cosmetics.

The fragrance contains one colorant, but since the amount of divalent iron salt is extremely small, it is mixed with iron salt and a spreading agent.
If phenols, mercaptans, cation activators, etc. are mixed as raw materials or as impurities,
Since it will be impossible to add the effects of the divalent and trivalent iron salt of the present invention to cosmetics, it is necessary to thoroughly check in advance.

As a method for checking the ability of the divalent and trivalent iron salt of the present invention to inhibit ionic reactions, there are various methods such as the Pioaf method, but the following method is the simplest method.

For the ion reaction inhibition test for cosmetics, use the cosmetic base as it is, dilute it with purified water, or use the aqueous phase extracted with purified water as a sample, add an appropriate amount of reagent copper powder, disperse it, and then add nitric acid test solution. In the case of ordinary cosmetics, copper powder and nitric acid naturally react, generating H2 gas and turning the liquid blue due to the formation of copper nitrate, but due to the ion reaction with divalent and trivalent iron salts. In the case of cosmetics with blocking ability, the liquid is colorless and no H2 gas is observed to be generated, but this is probably because the dissolution of the copper powder and the ionic reaction force do not progress.

Similarly, by adding an appropriate amount of divalent and trivalent iron salts to an aqueous solution of cosmetic raw materials or a solution extracted with purified water for insoluble raw materials to cause a color reaction of copper ions, the divalent and trivalent components of cosmetic raw materials can be extracted. It is possible to test iron salt compatibility.

By the above method, cosmetics are manufactured after checking the compatibility of the raw materials with divalent and trivalent iron salts, and the manufactured cosmetics are checked again for the steel ion generation reaction. The effect of divalent and trivalent iron salts can be confirmed.

〔Effect of the invention〕

As described above, when the cosmetics containing iron salts of the present invention are applied to the skin, the following effects are observed due to the action of normalizing the functions of the living body.

(11 Enhancement of skin functions) Control of the shape of the skin surface by normalizing the physiological functions of the skin tissue, normal keratinization metabolism of the epidermis, sebum secretion, and normalization of water evaporation; It is possible to directly promote the normalization of the skin that is naturally present in the body, such as normal hair growth due to normal metabolism of pigment cells and appropriate distribution of pigments.

(2) Enhancement of regenerative ability Skin tissue originally has the ability to normalize and recover from deterioration of the skin surface due to malfunctions in the regenerative function, damage to the stratum corneum caused by the external environment, and abnormalities in sebum and moisture levels. Although,
By applying the cosmetics of the present invention, this regeneration function can be strengthened and recovered more quickly. For example, regeneration of hair loss, darkening of white hair, prognosis of inflammation, normalization of hyperkeratin abnormalities such as progressive palmar keratosis, removal of spots due to pigmentation, and cracks.

Recovery from epidermal abnormalities caused by lack of sebum membrane, such as red rash, is quickly achieved.

(8) Enhancement of adaptability to environmental changes The adaptability of the skin to external stimulants, cold, heat, and ultraviolet irradiation can be strengthened to maintain the skin's original protective function. For example, by suppressing the infiltration of antigenic substances from the outside, sensitizing skin disorders can be prevented.

In addition, it can promote the formation of a sebum film according to the external environment and protect the skin in a beautiful condition.

(4) Prevention of abnormal growth of microorganisms Skin troubles such as inflammation and suppuration due to abnormal growth of microorganisms attached from the outside and bacteria resident on the skin can be removed and prevented. For example, acne.

It can prevent skin abnormalities caused by the proliferation of microorganisms, such as armpit irritation, dandruff on the scalp, and itching.

It also eliminates the need for preservatives that are normally added to cosmetics.

Sensitized skin disorders caused by preservatives can also be prevented.

(5) Inhibition of harmful ion reactions Suppressing harmful ion reactions and free radical reactions, such as skin irritation reactions caused by external chemicals and the formation of peroxidized lipids in sebum components caused by ultraviolet irradiation, reduces skin aging. , can prevent hair loss, hair graying, etc.

By incorporating divalent iron salts, it is possible to prevent oxidative deterioration in cosmetics containing oils and fats, so there is no need for antioxidants for oils and fats, which tend to cause sensitized skin disorders. .

The cosmetics according to the present invention have extremely excellent effects not found in conventional cosmetics, in that, in addition to the efficacy and effect of individual cosmetics due to the various ingredients, they can be expected to have essential benefits for the six points listed above for the body's busyness. can demonstrate.

〔Example〕

Next, Examples and Comparative Examples will be given to concretely demonstrate the effects of the present invention, but the present invention is not limited to these Examples.

In addition, the compounding amount in the following examples is weight %.

Example 1゜ Lotion■Ethyl alcohol 5.0%■Glycerin 5.0%■Pyrrolidonka A
→'41 Sodium liquid 0.5% - ■Niracol bifumin 0.2% (amino acid mixture manufactured by Nikko Chemical) ■Fragrance, appropriate amount @F@2
C1, -XH20C neutral lipid carrier') 1(f”
91; (h, C1,, h shite) ■ Add purified water to make a total of 1
00.0%.

Add ① to ② to manufacturing method ②, stir and dissolve, and filter this to obtain a lotion.

Comparative Example 1゜A lotion was prepared using the same formulation as in Example 1, excluding the divalent and trivalent iron salts.

Copper powder and copper powder were used as samples for the lotions of Examples and Comparative Examples, respectively.
When an ionization reaction test is performed by adding nitric acid, in the comparative example, H2 gas is generated and a blue coloring reaction of copper nitrate is observed, but in the example, the reaction does not proceed and ions due to divalent and trivalent iron salts are generated. It was recognized that this lotion has a reaction inhibiting effect.

The results of a panel test of this lotion by 50 monitors showed that it had a higher moisturizing effect than the comparative example and showed a significant improvement in dry skin.

Rush example 9 Milky low scene■Liquid paraffin λG%■Squalane 8,0%■Glycerin
7.0% ■ Polyoxyethylene monostearate 1.0% ■ Sorbitan sesquioleate
0.8%■ Carbo medium dividivinyl polymer
0.2% ■ Potassium hydroxide 0
．． 1%■Fragrance Appropriate amount■Fe2
CJ5-XH,0 (neutral lipid carrier) 1 ft
2X (FI!2'4 tL7) [Phase] Add purified water to make the total volume 100.0%.

Production method ■Disperse ■ in ◎, add ■ to neutralize it, then add ■ to homogeneously dissolve and disperse the mixture, heat it to 70℃, and add ■ to ■ to it by heating and dissolving it at 0℃. Add and emulsify,
After preparing the emulsified particles with a homogenizer, stir and cool, and
After adding ■ at 0°C, stir to room temperature to obtain milky low sheen.

Comparative Example: Using the same formulation and manufacturing method as in Example 2, ■Milky Low Sheen was prepared without the divalent and trivalent iron salts.

Regarding the Milky Roshe of Examples and Comparative Examples, an ionization reaction test with copper powder and nitric acid was conducted on the aqueous phase after acidifying both the oil and fat components and free resin components.・N was found to be a milky low sheen with no coloration due to copper ions and an ionic reaction inhibiting effect due to the divalent and trivalent iron base.

As a result of a panel test conducted by 50 monitors, the Milky Low Sheen of the example was found to be non-irritating to dry skin such as xerosis, to have a high moisturizing effect, and to reduce dryness and itching of the skin.

Example 8゜Cosmetic cream ■Polyoxyethylene monostearate 10
．． 0%■Glyceryl monostearate 5.0
%■Beeswax 1.0%■Liquid paraffin to%■Silicone oil 4.0%■Glycerin
15.0%■Aminomethylpropanol
0.2% ■Fragrance Appropriate amount @F@8C1, -XH20C Neutral fat 'JR carrier)
1 (r12X%Q!-vomit) ■ Add purified water to make the total volume Zoo, 0%.

Production methods ■~■ were heated to 70°C, and added to a solution of ■, ■, and [phase] heated and dissolved at 0°C to emulsify. After preparing emulsified particles with a homogenizer, stir and cool. After adding ■ at ℃ r! Cool and stir until A to obtain a cosmetic cream.

Comparative Example 8゜A cosmetic cream was prepared using the same treatment and manufacturing method as in the example except for excluding divalent and trivalent iron salts.

When we conducted an ionization reaction test with copper powder and nitric acid on the aqueous phase of the creams of Examples and Comparative Examples, which had been acidified to separate the oil and fat components, we found that the creams of Examples had no coloration due to copper ions, and showed no coloration due to copper ions. The cream was found to have the effect of inhibiting ion reactions caused by salt.

As a result of a panel test conducted by 50 monitors, the cosmetic cream of the example did not cause irritation even when rubbed on sensitive skin with inflammation such as atopic dermatitis, and the healing of the inflamed area was promoted.

Example 4 Cosmetic oil ■ Natural vitamin E oil 5.0% ■ α-bisabolol 0.1% ■ Olive oil makes the total amount 100.0%.

Production method ■ and ■ are added to ■, dissolved, and divalent and trivalent iron salt (neutral lipid carrier) iFg/j! Add a 10.0% aqueous solution, shake well, remove the separated aqueous phase, and dehydrate with anhydrous sodium sulfate to obtain a cosmetic oil.

As a comparative example, a cosmetic oil was prepared using the same treatment as in Example 4, but without the shaking treatment using divalent and trivalent iron salts. .

In both Examples and Comparative Examples, the same amount of M-made water was added and shaken well, and the separated aqueous phase was subjected to an ionization reaction test with copper powder and nitric acid.
It was observed that ionic reactions were suppressed.

As a result of a panel test conducted by 80 monitors, it was found to be effective in alleviating xeroderma and pruritus, as well as removing foul odors, crabs, and irritation caused by microorganisms in areas with thin stratum corneum and mucous membranes.

Example 5゜Cosmetic pack■Polyvinyl alcohol 15.0%■Glycerin 5.0%■Water-soluble polysiloxane copolymer 8.0%■Ethylene glycol
1.0% monostearate F・8C718・XH20 (neutral lipid carrier)
1 F' 2X (as F・8C18) ■Fragrance
Add an appropriate amount of purified water to make the total volume 100.0%.

Add ■ and ■ to manufacturing method ■, heat and dissolve, add the heated melt of ■ to ■, mix uniformly, cool, and heat to 40℃.
Add (■) below, stir, and cool to room temperature to obtain a pack.

Comparative Example 5 A pack was made using the same formulation as in Example 5, but without the addition of divalent and trivalent iron salts.

When the 10% aqueous solutions of the packs of Example 5 and Comparative Example were subjected to an ionization reaction test using copper powder and nitric acid, it was found that there was no coloring of copper ions in Examples, and that the ionic reaction was suppressed.

The results of a panel test conducted by 50 monitors showed that dry skin,
There was an improvement in oily skin, and there was no irritation in inflamed and eczema areas, and a healing effect was observed.

Example 6゜Shampoo ■Alkyl sulfate triethanolamine solution 20.
0%■Polyoxyethylene/alkyl ether 2
5.0% sodium sulfate solution■ Coconut oil fatty acid jetanolamide 5.0
%■Glycerin 10.0%■Fragrance
Appropriate amount @F@, (J,,X
H2O (4) IJ, 7M carrier) ltr”%5
'hf: 16) ■ Add purified water to total volume 100.0
%.

Add ① to ② in order to manufacturing method ② and heat and dissolve to obtain shampoo.

Comparative Example 6゜A shampoo is made using the same formulation as in Example 6, except that ■ divalent and trivalent iron salts are excluded.

When an ionization reaction test using copper powder and nitric acid was performed on a 10% aqueous solution of both, it was found that in the example, there was no coloration of copper ions, and the ionic reaction was suppressed.

As a result of an 8-month continuous use test conducted by 50 monitors, a clear reduction in the occurrence of dandruff and itching was observed with regular hair washing.

Example? .

Hair tonic■Ethanol 65. ON'■Resorcinol 0.1%■Capsicum 5.0%■! −Menthol
0.5% ■ Glycerin
5.0% ■ Polyoxyethylene monostearate
2.0%■Fragrance Appropriate amount■F・2C16α valve P (neutral lipid carrier) 11~
(As ``2'4'') ■Add purified water to make 100.0% total amount
shall be.

Add (1) to (2) in sequence to Production Method (2), heat and dissolve, cool and filter to obtain a hair tonic.

Comparative Example 7゜A hair tonic was prepared using the same formulation as in Example 7, but without the addition of divalent and trivalent iron salts.

When an ionization reaction test using copper powder and nitric acid was performed on both samples, it was confirmed that the ion reaction was suppressed without any coloration of copper ions observed in the example.

In a 6-month long-term continuous use test conducted by 50 monitors, 80 people found a clear reduction in hair loss, a hair growth effect, and a reduction in dandruff and itching.

Example 8゜Foundation scene■Titanium oxide 5.0%■Mica 50.0%■Talc
20.0% ■ Stear food Aluminum 5.0% ■ Silicic anhydride
6.0% ■ Phytosterol
20% ■ Polyoxyethylene monostearate
0.5%■Silicone oil
7.0% ■Vaseline 8.
5% ■ Inorganic pigment appropriate amount ■ Fragrance appropriate amount @ F @ 2C1, -X
H, O (medium performance [carrier)] 11"J, (as σS 4) Manufacturing method ■ ~ ■ and 0 were mixed and heated and melted ■ ~ ■ and ■
, ■, mix thoroughly, and press this into whole blood to obtain foundation sheen.

Comparative Example 8゜Foundage Yukin was prepared using the same recipe as in Example 8 except that ■ = iron salt was excluded.

When an ionization reaction test using copper powder and nitric acid was performed on the aqueous phase obtained by extracting both with purified water, no coloration of copper ions was observed in the example, and it was recognized that the ion reaction was suppressed.

As a result of a panel test conducted by 80 monitors with sensitive skin, none of the monitors felt that the Foundation Sheen of the Example was irritating to the skin, and it was observed that the longevity of makeup was improved.

Example 9゜Lipstick■Carnauba wax 10.0%■Candelilla wax 5.0%■Setanol
5.0% ■ Phytosterol
10.0% ■ Squalane
10.0% ■ Pigment appropriate amount ■ Fragrance appropriate amount ■ Add castor oil to make the total amount 100.0%.

Manufacturing method castor oil f F*2CJ5 ・XH2O (neutral fat J
ii body) If”g/j aqueous solution (as F@, C4,)
10% is added and shaken, the separated aqueous phase is removed, and 1 to 2 are added to castor oil dehydrated with anhydrous sodium sulfate, dissolved by heating, poured into a mold, cooled and solidified to obtain a lipstick.

Comparative Example 9 Example 9 using castor oil not treated with divalent and trivalent iron salts
Make lipstick using the same formula.

When an ionization reaction test using copper powder and nitric acid was performed on the aqueous phase portion of both samples, which were heat-treated with the same amount of purified water and then cooled, there was no coloration of copper ions in the example, and it was confirmed that the ionic reaction was suppressed.

The results of a panel test conducted by 50 female monitors showed that there was no irritation and the condition of the oral cavity surface, which tends to dry, was greatly improved.

Patent applicant: IBM Ltd. Reason Man u Sa look Tadashi Man

Claims (1)

[Claims] A cosmetic product characterized by containing divalent and trivalent iron salt.