JPH02108612A - Divalent and trivalent complex iron salt-compounded cosmetic - Google Patents

Abstract

PURPOSE:To provide a cosmetic having activities such as the promotion of skin physiological functions, the strengthening of regenerating ability, the increase of adaptability to environmental changes, the inhibition of the abnormal multiplication of microorganisms, the inhibition of injurious ionic reactions, etc., in addition to conventional potencies and activities by compounding a divalent and trivalent complex iron salt. CONSTITUTION:A divalent and trivalent complex iron salt, preferably a spinel type compound composed from divalent and trivalent iron ions, is preferably carried on an inorganic carrier such as diatomaceous earth or titanium dioxide or an organic carrier such as vegetable fibers or pulp and subsequently added to one of various cosmetics in a carrier-containing amount of 1.0-10<-10>g, preferably 10<-1>-10<-5>g, per 100g of the basic materials of the cosmetic to provide a cosmetic which allows living bodies to recover the non-ionic reaction systems thereof to normalize the functions of the living bodies and exhibits the above-mentioned activities having not appeared in conventional cosmetics in addition to the respective potencies and activities of the compounding components. Since the iron salt can prevent the oxidative changes of cosmetics compounded with fats and oils, the cosmetic does not require any antioxidant for the fats and oils liable to cause sensitized skin diseases.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to cosmetics containing bivalent and trivalent complex iron salts that have extremely unique physiological effects such as biological activity, ionization suppressing effect, and antiseptic effect. It is.

[Conventional technology] Cosmetics are defined in the Pharmaceutical Affairs Law.

There are a wide variety of products on the market that are used to condition the skin and hair naturally or artificially, such as lotions, milky lotions, creams, shampoos, conditioners, hair tonics, lipsticks, and 7-underwear. has been done. In order to further clarify the effects of each of these cosmetics, natural and synthetic raw materials such as various moisturizing agents, oil and fat components, surfactants, fragrances and pigments are used, and each ingredient has its own effects. It has been obtained.

However, due to recent environmental pollution and the accumulation of social stress, the skin's natural physiological functions have weakened, causing skin problems such as rough, dry, and sensitive skin, and hair abnormalities such as hair loss and graying to become very noticeable. It's coming. If conventional cosmetics are used in such a condition, the physiological functions of the skin will further deteriorate, and the number of problems caused by cosmetics has increased significantly.

[Problems to be Solved by the Invention] In view of the actual state of cosmetics, there is a desire to develop cosmetics that restore the natural physiological functions of the skin while fully satisfying the definition of cosmetics under the Pharmaceutical Affairs Law. To solve this problem, it has not been possible to solve this problem by relying solely on the direct effects of individual ingredients in cosmetics, which have been studied to date.For example, moisturizers for the purpose of rehydrating dry skin Hyaluronic acid, water-soluble protein, stain removal, whitening vitamins (J-conductor, etc.) can achieve some desired effect, but in reality, the durability of the effect or the deterioration of the ingredients after application can cause skin irritation. Problems such as 1.v remain in terms of irritation, and the effect of restoring the skin's natural physiological functions has not yet been achieved.

Considering the above facts, it can be used with confidence even on troubled skin such as rough skin and sensitive skin, and it can also be used with confidence due to the skin's natural defenses against a.
Raw J such as m function, respiratory function 1 secretion function! We have conducted extensive research into cosmetics that can restore JAL function to its normal state. As a result, only cosmetics containing specific bivalent and trivalent complex iron salts have the benefits of conventional cosmetics, as well as the ability to improve skin function, enhance regeneration ability, and provide resistance to irritants caused by environmental pollution. strengthening, prevention of microbial contamination,
Conventional cosmetics, such as blocking harmful ion reactions, can protect the skin from its natural normal state! # It has been discovered that it is possible to perform a function.

That is, the present invention has been researched and developed in view of the above-mentioned problems, and its purpose is to provide cosmetics containing divalent and trivalent complex iron salts having the stated purpose. Means for Solving J The divalent and trivalent complex iron salts used in the cosmetics of the present invention are iron hydrochlorides, sulfates, and
Inorganic salts such as phosphates and nitrates and formates, vinegar salts,
Examples include complex salts of divalent iron and trivalent iron such as organic salts such as propionate. The most preferable divalent and trivalent composite iron salt is a spinel-type compound composed of divalent and trivalent iron ions. An aqueous solution of an aqua complex of partially oxidized divalent and trivalent iron salts is optimal.

When these divalent and trivalent composite iron salts are dissolved in water or applied to a composite surface such as the skin surface, they suppress various ionic reactions due to changes in physical properties such as structuring of water.
It has been found that it induces reactions that are significantly different from ionic reactions in normal aqueous systems. All normal reactions in the body.

Since it is the same type of reaction system as the nonionic reaction system using the above divalent and trivalent complex iron salt, cosmetics containing this divalent and trivalent complex iron salt can be applied to abnormal biological systems.

The normal nonionic reaction system within the body is restored, allowing the body to return to its normal state.

When blending the above bivalent and trivalent complex iron salts, depending on the properties of the cosmetic, the type of compounding agent, and the desired effect, not only the divalent and trivalent complex iron salts may be blended alone, but also sodium chloride, sodium chloride, etc. Sodium oxide, ammonium chloride, ammonium sulfate, magnesium chloride, diatomaceous earth 1m titanium,
Inorganic substances such as silica and alumina, and vegetable miscellaneous substances,
It is most preferable to use organic substances such as pulp, vitamins, hormones, proteins, and lipids as a carrier to support the divalent and trivalent complex iron salt.

In order to obtain the divalent and trivalent composite iron salt of the present invention, the following method is preferable. Then, some of the divalent iron ions are oxidized into trivalent iron ions by blowing air or by forced stirring. After that, after removing the excess hydroxide or hydrated oxide of divalent and trivalent iron,
Neutralize the mother liquor with an acid such as sulfuric acid and concentrate under reduced pressure to 80%
By-product inorganic salts are fractionated and purified using (w/w)% hydrous alcohol such as an isopropyl alcohol solution to obtain a divalent and trivalent composite iron salt.

Also, as an alternative.

11m An aqueous solution of magnetite powder (Fe - Fe2 ・O,) dissolved in a strong acid is poured into an alkaline solution, and after removing the excess iron salt precipitate, it is neutralized, concentrated, and the by-product inorganic salts are removed using hydroalcohol. The divalent and trivalent composite iron salt of the present invention can be obtained by repeating the removal operation.

In this manufacturing method, sodium hydroxide is used as the alkali and 11! If an acid is used, a complex iron salt with a sodium chloride carrier is obtained, and if sulfuric acid is used for neutralization, a complex iron salt with a sodium sulfate carrier is obtained.

In addition, by adding an appropriate surfactant and fats and oils such as olive oil and squalane to an aqueous solution of purified bivalent and trivalent complex iron salts and concentrating the emulsified or solubilized solution, complex iron salts as lipid carriers can be prepared. is obtained.

Furthermore, if diatoms or titanium oxide are soaked in an aqueous solution of bivalent and trivalent complex iron salts and then dried, a complex iron salt with an inorganic carrier can be obtained.If vegetable fiber or pulp powder is soaked and dried, organic A fibrous carrier composite iron salt can be obtained.

The amount of divalent and trivalent composite iron salt should include the carrier.

1. per 100g of cosmetic base material. og-10-''g, preferably in the range of 10 to 10-5g.If the amount is greater or less than this range, the effect of the nonionic reaction system will be weakened.

Cosmetics that can be formulated with bivalent and trivalent complex iron salts include basic cosmetics such as lotions, emulsions, creams, packs, and cosmetic oils, hair cosmetics such as shampoos, hair tonics, and hair restorers, and lipsticks. It can be applied to almost all cosmetics, including makeup cosmetics such as foundation and blusher. However, it is necessary to select and use water-soluble or water-dispersible carriers, oil-dispersible carriers, and powder carriers in consideration of the shape and uniform dispersibility of the cosmetic product.

The pH of the cosmetics used can range from 3 to 11, but pH 5 to 8 is the most preferable range.

The cosmetics of the present invention contain 1 solvents, oils and fats, surfactants, and preservatives that are commonly used in cosmetics.

It can be used in combination with fragrances, pigments, etc., but since the amount of divalent and trivalent complex iron salts is small, it is reactive with iron salts.
When some raw materials such as chelating agents, phenols, mercaptans, and cationic activators are mixed as raw materials or as impurities, they can suppress the various ionic reactions that were originally intended to produce cosmetics with the same effect as biological moisture. It is necessary to check carefully in advance.

Various methods can be used to check the ability of the divalent and trivalent complex iron salt of the present invention to inhibit ionic reactions, such as nuclear magnetic resonance method and bioacceleration method, but the following method is the most practical method. It can be raised.

For the ionic reaction inhibition test of cosmetics, use the cosmetic base as it is, dilute it with purified water, or use the aqueous phase extracted with purified water as a sample, add an appropriate amount of reagent copper powder, disperse it, and then add nitric acid test solution. Then, in the case of regular cosmetics,
Naturally, copper powder and nitric acid react, H2 gas is generated, and the liquid takes on the blue color of copper ions due to the production of copper nitrate, but in the case of cosmetics that have the ability to inhibit ionic reactions due to divalent and trivalent complex iron salts, Because the dissolution and ionization of the copper powder does not proceed, the liquid is colorless and no H2 gas is generated.As a result, a reaction system similar to the normal nonionic reaction system in living organisms is generated in cosmetics. I can confirm that there is.

Similarly, to check the formation of nonionic systems in cosmetic raw materials, add Tekmon's divalent and trivalent complex iron salt to an aqueous solution of the raw material or, in the case of insoluble raw materials, to a solution extracted with purified water to cause a color reaction of copper ions. By carrying out this test, it is possible to test the compatibility of cosmetic raw materials with divalent and trivalent composite iron salts.

By the above method, cosmetics are manufactured after checking the compatibility of the raw materials with bivalent and trivalent complex iron salts, and then the manufactured cosmetics are subjected to the copper ion generation reaction again to ensure normal in-vivo production. Cosmetics having a reaction system similar to a nonionic reaction system can be obtained.

〔Effect of the invention〕

As described below, when applied to the skin, the cosmetics containing bivalent and trivalent complex iron salts of the present invention restore the nonionic reaction system of the biological system and normalize the functions of the biological system, resulting in the following effects: The following effects are observed.

(1) Enhancement of skin physiological functions The physiological functions that skin tissues have, namely, normal keratinization and metabolism of the epidermis, sebum secretion, and normalization of water evaporation, control of the skin surface condition, and furthermore, hair matrix. Normal growth of hair through normal metabolism of cells and pigment cells, proper distribution of pigments, and normalization of the skin that is naturally present in living bodies can be directly promoted.

(2) Enhanced regenerative ability Skin tissue originally has the ability to normalize and recover from deterioration of the skin surface due to metabolic dysfunction, damage to the stratum corneum caused by the external environment, and abnormalities in sebum and moisture levels. There is 1
By applying the cosmetics of the present invention, this regeneration function can be strengthened and recovered more quickly. For example,
Prognosis such as regeneration of hair loss, darkening of white hair, and inflammation, normalization of hyperkeratin abnormalities such as progressive palmar keratosis, removal of spots due to pigmentation, and lack of sebum membrane such as cracks and red spots. Recovery of the resulting epidermal abnormalities is quickly achieved.

(3) Enhancement of adaptability to environmental changes The adaptability of the skin to external irritants, cold, heat, heat, and ultraviolet irradiation can be strengthened and the skin's original protective function can be maintained. By inhibiting the invasion of antigenic substances, sensitizing skin disorders can be prevented.

In addition, it can promote the formation of a sebum film according to the external environment and protect the skin in a beautiful state.

(4) Prevention of abnormal growth of microorganisms Removes and prevents skin problems such as inflammation and suppuration caused by abnormal growth of microorganisms attached from the outside and some bacteria resident on the skin. It can prevent skin abnormalities caused by the proliferation of microorganisms, such as scalp dandruff and itching.

Furthermore, by blending the bivalent and trivalent complex iron salt, preservatives that are normally blended in cosmetics become unnecessary, and sensitizing skin disorders caused by preservatives can be prevented.

(5) Suppression of harmful ion reactions Suppressing harmful ion reactions and free radical reactions, such as skin irritation reactions caused by external chemicals and the formation of peroxidized lipids in sebum components due to ultraviolet irradiation, reduces skin aging and hair loss. , can prevent hair graying, etc.

Furthermore, by incorporating divalent and trivalent complex iron salts, it is possible to prevent oxidative deterioration of cosmetics containing oils and fats, thereby eliminating the need for oil-based antioxidants that tend to cause sensitized skin disorders.

The cosmetics according to the present invention have extremely excellent benefits not found in conventional cosmetics in that, in addition to the effectiveness of individual cosmetics due to the various ingredients, they can be expected to have the above five essential benefits for living organisms. It can be effective.

[Example 1] Next, Examples and Comparative Examples will be given to concretely demonstrate the effects of the present invention, but the present invention is not limited to these Examples.

In addition, the compounding amount in the following examples is weight %.

X Agriculture■Production method of divalent and trivalent composite iron salt l 100ml of 1% aqueous solution of ferrous sulfate (F e SO 7 H20)! l to 2.0% sodium hydroxide solution l
In addition to stirring, air is blown into the solution while stirring to oxidize some of the divalent iron ions. After oxidation, excess iron hydroxide or hydrated oxide is filtered off, and the pH is adjusted to 6.5-7 with sulfuric acid.
．． After neutralizing to 0, the solution was concentrated to dryness under reduced pressure. Furthermore, the white residue is leached with 80% isopropyl alcohol solution, the leaching mother liquor and washing liquid are evaporated, and the leaching mother liquor and washing solution are evaporated and dissolved in 100 mJ1 of purified water to obtain a composite iron salt aqueous solution.
00 times diluted solution and 10 ml each of 1% sodium sulfate solution as a control were placed in a 50 mM Nessler tube, 0.1 g of electrolytic copper powder was added, and the mixture was shaken well. When 5 mJ1 of 10% nitric acid test solution was added, sulfuric acid The sodium solution immediately generates hydrogen gas and the reaction solution takes on the blue color of copper ions, but the reaction does not proceed with the aqueous solution even if it is left at room temperature for 24 hours, demonstrating the ability of the aqueous solution of the present invention to inhibit the ionization reaction. It is recognized that there is.

Production method of divalent and trivalent composite iron salt 2 fI m Hydrochloric acid 8m of magnetite powder (Fa ・Fe 2 04)
2. Dissolved in Jl. Add to θ% sodium hydroxide aqueous solution 1M and stir. After standing for about 1 hour, the washed product is filtered, neutralized with hydrochloric acid to a P) of 16.5 to 7.0, and then evaporated to dryness under reduced pressure. The residue is leached with 80% aqueous alcohol, and the leaching mother liquor and wash liquor are combined and evaporated to dryness. Furthermore, by repeating this alcohol treatment, approximately 0
．． 1 g of white crystals are obtained. When this crystalline powder was dissolved in a small amount of purified water, divalent and trivalent iron salts were confirmed by color reaction with potassium ferricyanide and orthophenanthroline.

Example 3 Lotion ■ Ethyl alcohol 5.0% ■ Glycerin 5.0% ■ Sodium pyrrolidone carboxylate solution, 5% ■ Appropriate amount of fragrance ■ Divalent and trivalent composite iron salt aqueous solution of Example 1 0.1% ■ Purification Make water ioo, o.

Add ① to ② to manufacturing method ②, stir and dissolve, and filter this to obtain a lotion.

Comparative Example A lotion was prepared using the same formulation as in Example 3, excluding the divalent and trivalent complex iron salt.

Copper powder and copper powder were used as samples for the lotions of Examples and Comparative Examples, respectively.
When an ionization reaction test is performed by adding nitric acid, H2 gas is generated in the comparative example, and a blue coloring reaction of copper nitrate is observed, but in the example, the reaction does not proceed, and the reaction is caused by divalent and trivalent composite iron salt. It was confirmed that this lotion has an ionic reaction blocking effect.

The results of a panel test of this lotion by 50 monitors showed that it had a higher moisturizing effect than the comparative example, and showed a significant improvement in dry skin.

X Noh 1 Milky Rosy, N ■Liquid paraffin ■Squalane ■Glycerin ■Polyoquine ethylene monostearate 2.0% 3.0% 7.0% 1.0% ■Sorbitan sesquioleate 0.3% ■Carboxyvinyl Polymer 0.2% ■ Potassium hydroxide 0.1% ■ Fragrance
Appropriate amount ■ Bivalent and trivalent composite iron salt of Example 2 i
o" 3% [phase] purified ice plus 100.0
Ru.

Disperse the manufacturing method (B) into cicadas, add ■ to neutralize it, and make coarse Φ
was added, uniformly dissolved and dispersed, and heated to 70°C.
To this, add and emulsify a solution of ■~■ heated to 70℃, prepare the emulsified particles with a homogenizer, stir and cool, add ■ at 40℃, stir to room temperature, and make a milky lotion. get.

Comparative Example A milky lotion with the same formulation and manufacturing method as in Example 4 except for the divalent and trivalent complex iron salt is prepared.

For the milky lotions of Examples and Comparative Examples, an ionization reaction test with copper powder and nitric acid was performed on the aqueous phase after acidifying both oil and fat components and free resin components. It was confirmed that the milky lotion had no coloration caused by the divalent and trivalent complex iron salt and had the effect of inhibiting the ionic reaction caused by the divalent and trivalent complex iron salt.

As a result of a panel test conducted by 50 monitors, the milky lotion of the example was found to be non-irritating to dry skin such as xerosis, to have a high moisturizing effect, and to reduce dryness and itching of the skin.

Shaku Wataru 1 Cosmetic cream (shi) Polyoxyethylene 10.0% Monostearate ■ Glycerin monostearate 5.0% ■ Beeswax 1.0% C) Liquid paraffin 4JO% ■ Silicone oil
4.0% ■ Glycerin
15. o%■ Aminomethyl propatool 0
．． 2% ■Fragrance Appropriate amount φ) Divalent and trivalent complex iron salt (squalane carrier) 10" 3% 0 fine wood Add 100.0%.

Manufacturing method ■~■ and ■ are heated to 70°C. ■, [phase] is heated and dissolved at 70°C, and emulsified by stirring. After preparing the emulsified particles with a homogenizer, stirring and cooling to 40°C. After adding ■, cool to room temperature and stir to obtain a cosmetic cream.

Comparative Example A cosmetic cream was prepared using the same formulation and manufacturing method as in Example 5, excluding the divalent and trivalent complex iron salt.

An ionization reaction test using copper powder and nitric acid was conducted on the creams of Examples and Comparative Examples on the aqueous phase from which the oil and fat components had been acidified and the oil and fat components had been separated. It was confirmed that the cream has the effect of inhibiting ion reactions caused by iron salts.

As a result of a panel test conducted by 50 monitors, the cosmetic cream of the example did not cause irritation even when applied to sensitive skin with inflammation such as atopic dermatitis, and healing of the inflamed area was promoted.

Xoyu 1 Cosmetic oil ■Natural vitamin E oil 5.0%■α-Bisabolol o, i%■With olive oil
Set to 100.0%.

Production method ■ and ■ are added to ■, dissolved, and 0.5% of anhydrous sodium sulfate containing a divalent and trivalent complex iron salt obtained by scouring the by-product of Example 1 is added and stirred well. A cosmetic oil is obtained by filtering off the anhydrous sodium sulfate.

Comparative Example A cosmetic oil is prepared using the same formulation as in Example 6 using anhydrous sodium sulfate containing a divalent and trivalent complex iron salt without undergoing the shaking treatment.

In both Examples and Comparative Examples, the same amount of purified water was added, shaken well, and the separated aqueous phase was subjected to an ionization reaction test using copper powder, v+m. It was observed that the reaction was suppressed.

The results of a panel test conducted by 30 monitors showed that xeroderma and pruritus were reduced, and it was found to reduce odor and itching caused by microorganisms in areas with thin stratum corneum and mucous membranes.

It was found to have the effect of removing irritation.

Fire Mu Al Cosmetic Pack■Polyvinyl alcohol 15.0%■Glycerin 5.0%■Water-soluble polysiloxane Symbiotic hardware 3.0%■Ethylene glycol
1.0% monostearate (bivalent and trivalent composite iron of Example 2 + lf!10-3%■
Then it becomes 100.0.

Add ■ and ■ to manufacturing method ■, heat and dissolve, and add ip to ■
Add heated and melted solution, mix uniformly and cool.
Add (■) at below ℃, stir, and cool to room temperature to obtain a pack.

Comparative Example A pack is prepared using the same formulation as in Example 7, but does not contain divalent and trivalent complex iron salt.

When the 10% aqueous solutions of the packs of Examples and Comparative Examples were subjected to an ionization reaction test using copper powder and nitric acid, it was found that there was no coloration of copper ions in Examples and that the ion reaction was suppressed.

The results of a panel test conducted by 50 monitors showed that dry skin and oily skin were improved, and there was no irritation on inflamed and eczema areas, and a healing effect was observed.

Example 8 Shampoo■Fragrance Appropriate amount■Alkyl sulfate triethanol 20.0% Amine solution■Polyoxyethylene alkyl 25.0% Sodium ether sulfate Lotion Coconut oil fatty acid jetanolamide 5.0%■Glycerin 10.0%■Fragrance
Appropriate amount■ Divalent and trivalent composite iron salt aqueous solution of Example 1 0.1%■ Separate addition 100.0
That's what I mean.

Add ① to ② in order to manufacturing method ② and heat and dissolve to obtain shampoo.

Comparative Example A shampoo was prepared using the same formulation as in Example 8 except for the following: (1) divalent and trivalent complex iron salts were excluded.

When an ionization reaction test using copper powder and nitric acid was performed on 10% aqueous solutions of both, it was found that in the example, there was no coloration of copper ions, and the ionic reaction was suppressed.

As a result of a 3-month continuous use test conducted by 50 monitors, a clear reduction in the occurrence of dandruff and itching was observed with the normal number of hair washes.

X Mu Yuyu Hair Tonic ■ Ethanol 65.0% ■ Resorcinol O01% ■ Capsicum + 5.0% ■ Text - Menthol
0.5% ■ Glycerin
5.0% (I3) Polyoxyethylene monostearate 2.0% ■Fragrance Suitable I■Made by divalent and trivalent complex iron salt (vitamin E carrier) io'''%■ Add 100.0%.

Steps 1 to Φ) were added to method 1 and dissolved by heating, and after cooling, the mixture was filtered to obtain Hair Tony 2.

Comparative Example Using the same formulation as in Example 9, ■Do not include divalent and trivalent complex iron salt.\ Atonic is made.

When an ionization reaction test using copper powder and nitric acid was conducted for both, no coloration of copper ions was observed in the example, and it was recognized that the ion reaction was suppressed.

In a 6-month long-term continuous use test conducted by 50 monitors, 30 people found a clear reduction in hair loss, a hair growth effect, and a reduction in dandruff and itching.

Example 10 Foundation ■ Titanium oxide ■ Mica ■ Talc ■ Stearin Ugly aluminum ■ Silicic anhydride ■ Phytosterol ■ Polyoxyethylene monostearate ■ Silicone oil ■ Vaseline @ inorganic pigment ■ Fragrance 5% 0% 0% 0% 0% 0% 5% 7.0% 3.5% Appropriate amount of divalent trivalent titanium 0.5' Manufacturing method ■～■ and [Co.], mixed with O and heated and melted ■～■
Add and ■, mix thoroughly, and press it all over the country to obtain a foundation.

Comparative Example A foundation is made using the same formulation as in Example 1O, except for the divalent and trivalent complex iron salt.

When an ionization reaction test using copper powder and nitric acid was performed on the aqueous phase obtained by extracting both with purified water, no coloration of copper ions was observed in the examples, and it was recognized that the ion reaction was suppressed.

As a result of a panel test conducted by 30 monitors with sensitive skin, none of the monitors found the foundation of the example to be irritating to the skin, and it was observed that the longevity of makeup was improved.

L Mu A Yuyu Lipstick ■ Carnauba wax 10.0% ■ Sheep Yanderilla wax 5.0% 0) Setanol
5.0% ■ Phytosterol
10.0% ■ Squalane
1000% Pigment
Appropriate amount■Fragrance Appropriate amount■) Add human oil to 100.0%.

Production method Castor oil is obtained by adding 1.0% of anhydrous sodium sulfate containing bivalent and trivalent complex iron salt obtained by refining the by-product sodium sulfate of Example 1, shaking the castor oil, and filtering off the anhydrous salt. Add ■ to ■, heat and dissolve, pour into a mold, cool and solidify to form a lipstick for 4 times.

Comparative Example A lipstick is made with the same formulation as χ flow side 11 using castor oil that is not treated with a divalent and trivalent complex iron salt.

When we conducted an ionization reaction test using copper powder and nitric acid on the aqueous phase that had been heat-treated with the same amount of purified water and then cooled, we found that in Example, there was no coloration of copper ions, indicating that the ionic reaction was suppressed. .

The results of a panel test conducted by 50 female monitors showed that there was no irritation and the condition of the lip surface, which tends to dry out, was greatly improved.

Patent applicant: Shizen Co., Ltd. Agent: Patent attorney Yoshiharu Yoshida

Claims (1)

[Claims] A cosmetic product characterized by containing a divalent and trivalent composite iron salt.