KR100461085B1 - Hair cosmetics composition - Google Patents

Abstract

The present invention relates to a hair cosmetic composition for increasing the anti-dandruff and itching treatment effect of the scalp by using a mixture of alpha-hydroxy acid and pyroxtonolamine.

Description

Hair cosmetic composition

The present invention relates to a hair cosmetic composition for increasing the anti-dandruff and itching treatment effect of the scalp by using a mixture of alpha-hydroxy acid and pyroxtonolamine.

In general, dandruff refers to a mass of dead cells of the scalp that come off in a hard keratin form and merged with sebum, sweat, etc. secreted from the scalp. And dandruff is usually irritated by the scalp, such as sebum and accompanied by itching. At this time, if you scratch the scalp hard, it will hurt and eventually cause inflammation, causing eczema and hair loss.

Conventionally, zinc pyrithione is used in hair cosmetics for the purpose of preventing dandruff and treating itching. However, this material is insoluble in water and has a high specific gravity, which makes it difficult to uniformly disperse it in the composition, and in particular, because it has high eye irritation, Usage limits are limited when used (see Gene A. Hyde and Mark M. Auerbach, Formulation Techniques for Zinc Pyrithione Antidandruff Shampoos, Cosmetics and Toiletries, 94, 57, April 1979 and Fred H. Snyder, etc.) Pyridiethiol 1-Oxide in Shampoo Formulation Toxicology and Applied Pharmacology, 7, 425-437, 1965).

Recently, in order to compensate for the drawbacks of the zinc pyrithione, pyroctonolamine has been used in the hair cosmetic composition, and in the case of this component, the use of 0.5 to 2.0% by weight is required to show a sufficient effect. However, this ingredient is also regulated due to safety issues on the human body (Cosmetics and Toiletries, 102, 6, Dec., 1987).

Japanese Patent JP 06234618 (Kao), previously published, uses zinc pyrithione and pyrotonolamine as a rinse for anti-dandruff purposes, and Japanese Patent JP 08012535, previously applied, is a shampoo that provides anti-dandruff, good dispersibility, and conditioning effect. Zinc pyrithione was used as a composition for the purpose of preventing dandruff. Although zinc pyrithione and pyroxtonolamine are recognized for their anti-dandruff effects, they have problems in terms of safety to the human body.

Therefore, the present inventors while researching how to give an anti-dandruff, itching treatment effect effectively without stimulation to the human body, when applying the hair cosmetic composition containing alpha-hydroxy acid to the hair anti-dandruff and itching treatment effect And it was found that the synergistic effect is further obtained when used in combination with the pyrotonolamine used in the hair cosmetic composition for the same purpose to complete the present invention.

The present invention relates to a hair cosmetic composition, characterized by containing al-hydroxy acid and pyrotonolamine.

Alpha-hydroxy acid is a generic name for straight-chain acids having 2 to 6 carbon atoms with a hydroxy group in the alpha position. Specific examples include malic acid, citric acid, tartaric acid, glycolic acid, and lactic acid (Figure 1). In, tartaric acid was extracted from grapes, glycolic acid was extracted from sugar cane, and lactose was extracted from milk.

Figure 1. Alpha-hydroxy acid

Alpha-hydroxy acid and its derivatives are effective in treating dry skin because they increase the water retention of the stratum corneum.

In the May 1995 issue of the Journal of Drugs & Cosmetics & Industries and the December 1994 issue of the Fragrance Journal, alpha-hydroxyacids reduce the binding capacity of cells bound to the stratum corneum, helping dead cells fall off, resulting in overly keratinized skin. Have been reported to have excellent cell renewal effects (see Bernade Inson, Retinoids and AH As, Drugs & Cosmetics & Industries, 24, May, 1995, Teruhisa Kaneko and Nahoko Nakashima, Grico-Lu / 乳酸 の 角質 改善).效果, Fragrance Journal, 30, Dec, 1994).

In the September 1995 issue of the journal Soap Cosmetics Chemical Specialties, alpha-hydroxyacids were reported to have excellent effects on cell renewal, wrinkle reduction and skin smoothness (Walter P. Smith, Hydroxy Acids and Skin Aging).

The present invention uses a mixture of 1 to 10% by weight of alpha-hydroxy acid and pyroxtonolamine in conventional ingredients such as shampoo, hair conditioner and hair tonic, which are hair cosmetics, to provide synergistic effects in the prevention of dandruff and itching. It relates to a cosmetic composition. When using less than 1% by weight of the alpha-hydroxy acid is difficult to expect the effect, when using more than 10.0% by weight may cause problems in terms of human safety, limit the content of alpha-hydroxy acid to 1 to 10% by weight. . At this time, the ratio of alpha-hydroxy acid and pyroxtonolamine is not limited.

When using less than 0.1% by weight of pyrotonolamine it is difficult to expect the effect, when using more than 1.0% by weight there is a possibility of problems in terms of human safety, limit the content of pyrotonolamine to 0.1 to 1.0% by weight.

Hereinafter, the present invention will be described in more detail with reference to Examples, but these Examples do not limit the technical scope of the present invention.

Example 1-2 and Comparative Example 1-3

30% sodium lauryl sulfate, 30% polyoxyethylene lauryl sulfate, palm oil fatty acid diethanolamide, concentrated glycerin and alpha-hydroxy acid (glycolic acid having 2 carbon atoms) and pyrotonolamine After the addition, the mixture was warmed to a temperature of 60 ° C., dissolved uniformly, and cooled to 40 ° C. Subsequently, a dye (blue No. 1), paraoxybenzoate, fragrance, and triethanolamine were added to the mixture, followed by cooling to room temperature to prepare a shampoo.

Table 1.

Efficacy and effect experiments against dandruff and itching for the composition thus prepared were carried out according to the following test example and the results are shown in Table 2 and Table 4, respectively.

Antidandruff effect test example (1)

A total of 25 men and 50 women with dandruff were selected as test subjects and the shampoos of Table 1 were tested for 1 month. Before the start of the test, the weight of the dandruff collected by collecting the dandruff accumulated for three days and collecting the dandruff, and the weight of the dandruff accumulated three days after the end of the test by trituration every three days with the shampoo composition shown in Table 1 Comparative evaluation.

At this time, the accumulated dandruff was collected directly from the scalp using a vacuum suction device, and the rate of dandruff reduction was calculated according to the following equation. The dandruff prevention effect was judged to be effective only when the dandruff reduction rate is 25% or more.

In addition, a questionnaire for the anti-dandruff effect was administered to the test subjects.

Table 2.

Itching test (1)

50 people were selected from 25 men and women who felt itching as usual, and the products of Examples 1 and 2 and Comparative Examples 1 to 3 were used once every 2 days for 8 weeks, and then evaluated through the interview according to the following evaluation criteria. It was.

Table 3. Evaluation criteria for reducing itching

Table 4.

As shown in Table 2 and Table 4, the shampoo composition of Examples 1 to 2 using a mixture of alpha-hydroxy acid and pyrotonolamine according to the present invention has superior anti-dandruff and itching effect than Comparative Examples 1 to 3. Appeared.

Example 3-4 and Comparative Example 4-6

Fluid paraffin, self-emulsifying monostearic acid ester, paraoxybenzoic acid ester, 50% cetyltrimethylammonium chloride, concentrated glycerin, alpha-hydroxy acid, pyroxtoneolamine (glycol having 2 carbon atoms) Acid) was warmed up to 75 ° C. to dissolve, and the mixture was poured into purified water heated to 75 ° C., emulsified, and cooled to 40 ° C. Subsequently, a dye, a fragrance, and triethanolamine were added to the mixture, followed by cooling to room temperature to prepare a hair conditioner.

Thus prepared products were tested for efficacy and effects on dandruff and itching according to the following test examples and the results are shown in Tables 6 and 8, respectively.

Table 5.

Antidandruff effect test example (2)

A total of 25 men and 50 women with relatively high dandruff were selected as test subjects and the hair conditioners of Table 5 were tested for 1 month. Before starting the test, wash with a conventional shampoo and rinse with a conventional hair conditioner, and then collect the dandruff accumulated for three days, and the weight of the collected dandruff, and use it once every two days with the hair conditioner composition shown in Table 5 and after the end of the test 3 The weight of dandruff accumulated over the day was evaluated. The shampoo used during this test period was the shampoo used before the start of the test.

The results were determined to be effective only when the rate of dandruff reduction is 25% or more, and the dandruff collection and dandruff reduction rate were carried out in the same manner as in Test Example 1.

In addition, a questionnaire for the anti-dandruff effect was administered to the test subjects.

Table 6.

Itching removal effect test example (2)

Twenty five men and women each having an itching in general were selected as test subjects, and the products of Examples 3 to 4 and Comparative Examples 4 to 6 were used once every two days for 8 weeks, and then evaluated through interviews. During this test, the shampoo was made to use the usual shampoo.

Table 7. Evaluation criteria for reducing itching

Table 8.

As shown in Table 6 and Table 8, the hair conditioner composition of Examples 3 to 4 using the alpha-hydroxy acid and pyroxtonolamine according to the present invention is superior to the hair conditioner composition of Comparative Examples 4 to 6, itching and itching It has been shown to have a reducing effect.

Example 5-6 and Comparative Example 7-9

After mixing and dissolving l-menthol, D-panthenol, concentrated glycerin, pigment and flavor in ethanol at the composition ratio as shown in Table 9, polyoxyethylene hardened castor oil and alpha-hydroxy acid p (having 2 carbon atoms) in water Glycolic acid) and pyrotonolamine were dissolved to prepare a hair tonic.

Thus prepared products were tested for efficacy and effects on dandruff and itching according to the following test examples and the results are shown in Table 10 and Table 12.

Table 9.

Antidandruff effect test example (3)

50 men were selected from 25 men and women who had a lot of dandruff for 1 month. Before starting the test, the hair shampoo used in the prescription of Table 9 was used once a day while triturating the weight of the dandruff accumulated by 3 days and collecting the dandruff accumulated for 3 days and the conventional shampoo once every 2 days. The weight of the dandruff accumulated three days after the end of the test was evaluated. The shampoo used during this test period was the shampoo used before the start of the test.

The results were determined to be effective only when the rate of dandruff reduction is 25% or more, and the collection and dandruff reduction rates of dandruff were carried out in the same manner as in Test Example (1).

In addition, a questionnaire for the anti-dandruff effect was administered to the test subjects.

Table 10.

Itching elimination effect test (3)

50 people were selected as test subjects each of 25 men and women who usually felt itching, and the products of Examples 5 to 6 and Comparative Examples 7 to 9 were used once a day for 4 weeks, and then evaluated through interviews. During this test, the shampoo was made to use the usual shampoo.

Table 11.Evaluation Criteria for Itching Reduction

Table 12.

As shown in Table 10 and Table 12, the hair tonic composition of Examples 5 to 6 using a mixture of alpha-hydroxy acid and pyrotonolamine according to the present invention is more resistant to dandruff and less itching than the comparative examples 7 to 9 hair tonic composition. The synergistic effect of was found to be excellent.

Claims (3)

Hair cosmetic composition, characterized in that it contains 1.0 to 10.0% by weight of alpha-hydroxy acid and 0.1 to 1.0% by weight of pyrotonolamine. The hair cosmetic composition according to claim 1, wherein the alpha-hydroxy acid is malic acid, citric acid, tartaric acid, glycolic acid or lactic acid. The composition of claim 1 wherein the hair cosmetic is a shampoo, hair conditioner or hair tonic.