JPH02500327A - マイコバクテリアに対する遺伝子操作ワクチン - Google Patents
マイコバクテリアに対する遺伝子操作ワクチンInfo
- Publication number
- JPH02500327A JPH02500327A JP62505677A JP50567787A JPH02500327A JP H02500327 A JPH02500327 A JP H02500327A JP 62505677 A JP62505677 A JP 62505677A JP 50567787 A JP50567787 A JP 50567787A JP H02500327 A JPH02500327 A JP H02500327A
- Authority
- JP
- Japan
- Prior art keywords
- virus
- antigen
- recombinant
- box
- vaccinia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 229910052792 caesium Inorganic materials 0.000 description 1
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- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
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- ZJYYHGLJYGJLLN-UHFFFAOYSA-N guanidinium thiocyanate Chemical compound SC#N.NC(N)=N ZJYYHGLJYGJLLN-UHFFFAOYSA-N 0.000 description 1
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- ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 description 1
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- 238000007912 intraperitoneal administration Methods 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
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- 239000003607 modifier Substances 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 229940031348 multivalent vaccine Drugs 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
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- DFCXLPXOMCCXKM-UHFFFAOYSA-N phenylmethanesulfonic acid;hydrofluoride Chemical compound F.OS(=O)(=O)CC1=CC=CC=C1 DFCXLPXOMCCXKM-UHFFFAOYSA-N 0.000 description 1
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- 239000002157 polynucleotide Substances 0.000 description 1
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- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
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- 238000011002 quantification Methods 0.000 description 1
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- 238000012163 sequencing technique Methods 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- FHHPUSMSKHSNKW-SMOYURAASA-M sodium deoxycholate Chemical compound [Na+].C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC([O-])=O)C)[C@@]2(C)[C@@H](O)C1 FHHPUSMSKHSNKW-SMOYURAASA-M 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90466186A | 1986-09-08 | 1986-09-08 | |
US904,661 | 1986-09-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH02500327A true JPH02500327A (ja) | 1990-02-08 |
Family
ID=25419526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62505677A Pending JPH02500327A (ja) | 1986-09-08 | 1987-09-04 | マイコバクテリアに対する遺伝子操作ワクチン |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0323480A1 (fr) |
JP (1) | JPH02500327A (fr) |
AU (1) | AU8020387A (fr) |
IL (1) | IL83810A0 (fr) |
WO (1) | WO1988002027A1 (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7767449B1 (en) | 1981-12-24 | 2010-08-03 | Health Research Incorporated | Methods using modified vaccinia virus |
US5833975A (en) * | 1989-03-08 | 1998-11-10 | Virogenetics Corporation | Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence |
US5174993A (en) * | 1981-12-24 | 1992-12-29 | Health Research Inc. | Recombinant avipox virus and immunological use thereof |
EP0345021B1 (fr) * | 1988-06-02 | 1994-04-27 | Nippon Zeon Co., Ltd. | Antigènes des mycoplasmes aviaires et vecteurs recombinants contenant le gène ainse que diagnostics et vaccinsy le utilisant |
NZ231429A (en) * | 1989-11-17 | 1992-12-23 | Univ Massey | Diagnostic probes and their use in detecting mycobacterium paratuberculosis |
US5330754A (en) | 1992-06-29 | 1994-07-19 | Archana Kapoor | Membrane-associated immunogens of mycobacteria |
US7300660B2 (en) | 1993-11-23 | 2007-11-27 | The Regents Of The University Of California | Abundant extracellular products and methods for their production and use |
US6752993B1 (en) | 1993-11-23 | 2004-06-22 | The Regents Of The University Of California | Abundant extracellular product vaccines and methods for their production and use |
AU1097795A (en) | 1993-11-23 | 1995-06-13 | Regents Of The University Of California, The | Abundant extracellular products and methods for their production and use |
US6013660A (en) * | 1996-10-02 | 2000-01-11 | The Regents Of The University Of California | Externally targeted prophylactic and chemotherapeutic method and agents |
US6229001B1 (en) | 1997-01-03 | 2001-05-08 | Southern Research Institute | Mycobacterium fol a gene that encodes for the enzyme dihydrofolate reductase |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984002077A1 (fr) * | 1982-11-30 | 1984-06-07 | Us Health | Procede de production de recombinants du virus de la variole pour l'expression de genes etrangers |
-
1987
- 1987-09-04 WO PCT/US1987/002245 patent/WO1988002027A1/fr not_active Application Discontinuation
- 1987-09-04 AU AU80203/87A patent/AU8020387A/en not_active Abandoned
- 1987-09-04 JP JP62505677A patent/JPH02500327A/ja active Pending
- 1987-09-04 EP EP87906259A patent/EP0323480A1/fr not_active Withdrawn
- 1987-09-06 IL IL83810A patent/IL83810A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU8020387A (en) | 1988-04-07 |
WO1988002027A1 (fr) | 1988-03-24 |
EP0323480A1 (fr) | 1989-07-12 |
IL83810A0 (en) | 1988-02-29 |
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