JPH0242465B2 - - Google Patents
Info
- Publication number
- JPH0242465B2 JPH0242465B2 JP57081150A JP8115082A JPH0242465B2 JP H0242465 B2 JPH0242465 B2 JP H0242465B2 JP 57081150 A JP57081150 A JP 57081150A JP 8115082 A JP8115082 A JP 8115082A JP H0242465 B2 JPH0242465 B2 JP H0242465B2
- Authority
- JP
- Japan
- Prior art keywords
- aspartame
- maltitol
- sweetener
- granulation
- granules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 34
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 32
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims description 28
- 239000000845 maltitol Substances 0.000 claims description 28
- 235000010449 maltitol Nutrition 0.000 claims description 28
- 229940035436 maltitol Drugs 0.000 claims description 28
- 235000003599 food sweetener Nutrition 0.000 claims description 22
- 239000003765 sweetening agent Substances 0.000 claims description 22
- 239000008187 granular material Substances 0.000 claims description 21
- 239000011230 binding agent Substances 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000004519 manufacturing process Methods 0.000 claims description 8
- 238000000748 compression moulding Methods 0.000 claims description 6
- 238000005550 wet granulation Methods 0.000 claims description 3
- 108010011485 Aspartame Proteins 0.000 description 31
- 239000000605 aspartame Substances 0.000 description 31
- 235000010357 aspartame Nutrition 0.000 description 31
- 229960003438 aspartame Drugs 0.000 description 31
- 235000019441 ethanol Nutrition 0.000 description 25
- 238000005469 granulation Methods 0.000 description 16
- 230000003179 granulation Effects 0.000 description 16
- 239000000843 powder Substances 0.000 description 15
- 238000000034 method Methods 0.000 description 14
- 239000002994 raw material Substances 0.000 description 12
- 239000000546 pharmaceutical excipient Substances 0.000 description 9
- 239000007864 aqueous solution Substances 0.000 description 8
- 230000000704 physical effect Effects 0.000 description 7
- 238000001035 drying Methods 0.000 description 6
- 238000003756 stirring Methods 0.000 description 5
- 150000001298 alcohols Chemical class 0.000 description 4
- 238000007906 compression Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000000465 moulding Methods 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 239000006185 dispersion Substances 0.000 description 3
- 238000001125 extrusion Methods 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 229920001353 Dextrin Polymers 0.000 description 2
- 239000004375 Dextrin Substances 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 239000003125 aqueous solvent Substances 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 235000019425 dextrin Nutrition 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- -1 etc. Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 238000004898 kneading Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 235000013615 non-nutritive sweetener Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
Landscapes
- Seasonings (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57081150A JPS58198268A (ja) | 1982-05-14 | 1982-05-14 | 甘味料顆粒又はキユ−ブの製造法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57081150A JPS58198268A (ja) | 1982-05-14 | 1982-05-14 | 甘味料顆粒又はキユ−ブの製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58198268A JPS58198268A (ja) | 1983-11-18 |
| JPH0242465B2 true JPH0242465B2 (ko) | 1990-09-21 |
Family
ID=13738398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57081150A Granted JPS58198268A (ja) | 1982-05-14 | 1982-05-14 | 甘味料顆粒又はキユ−ブの製造法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58198268A (ko) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63251042A (ja) * | 1987-04-07 | 1988-10-18 | Yakult Honsha Co Ltd | 低カロリ−ヨ−グルト |
| DE69712332T2 (de) * | 1996-02-29 | 2002-10-02 | Fujisawa Pharmaceutical Co | Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung |
-
1982
- 1982-05-14 JP JP57081150A patent/JPS58198268A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58198268A (ja) | 1983-11-18 |
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